메뉴 건너뛰기




Volumn 21, Issue 4, 2000, Pages 557-561

Risk assessment in first degree female relatives of breast cancer patients using the alkaline Comet assay

Author keywords

[No Author keywords available]

Indexed keywords

ALKALI; METHYLNITRONITROSOGUANIDINE; MUTAGENIC AGENT;

EID: 0034007114     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.4.557     Document Type: Article
Times cited : (95)

References (49)
  • 4
    • 0028358348 scopus 로고
    • MDA-MD-453, an androgen-responsive human breast carcinoma cell line with high level of androgen receptor expression
    • Hall, R.E., Birrell, S.N., Tiley, W.D. and Sutherland, R.L. (1994) MDA-MD-453, an androgen-responsive human breast carcinoma cell line with high level of androgen receptor expression. Eur. J. Cancer, 30A, 484-490.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 484-490
    • Hall, R.E.1    Birrell, S.N.2    Tiley, W.D.3    Sutherland, R.L.4
  • 9
    • 0032579165 scopus 로고    scopus 로고
    • Risk assessment in cervical dysplasia patients by single cell gel electrophoresis assay: A study of DNA damage and repair
    • Udumudi, A., Jaiswal, M., Rajeswari, N., Desai, N., Jain, S.N., Balakrishna, N., Rao, K.V. and Ahuja, Y.R. (1998) Risk assessment in cervical dysplasia patients by single cell gel electrophoresis assay: a study of DNA damage and repair. Mutat. Res., 412, 195-205.
    • (1998) Mutat. Res. , vol.412 , pp. 195-205
    • Udumudi, A.1    Jaiswal, M.2    Rajeswari, N.3    Desai, N.4    Jain, S.N.5    Balakrishna, N.6    Rao, K.V.7    Ahuja, Y.R.8
  • 10
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N.P., McCoy, M.T., Tice, R.R. and Schneider, E.L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 12
    • 0023883022 scopus 로고
    • Increased frequency of sister chromatid exchanges in lymphocytes of breast cancer patients
    • Adhvaryu, S.C., Rawal, U.M., Patel, J.V., Patel, D.D. and Balar, D.B. (1988) Increased frequency of sister chromatid exchanges in lymphocytes of breast cancer patients. Int. J. Cancer, 41, 394-398.
    • (1988) Int. J. Cancer , vol.41 , pp. 394-398
    • Adhvaryu, S.C.1    Rawal, U.M.2    Patel, J.V.3    Patel, D.D.4    Balar, D.B.5
  • 13
    • 0029875191 scopus 로고    scopus 로고
    • Screening for genetic predisposition to mutagens in cancer patients
    • Gupta, R.S., Gupta, R. and Goldstein, S. (1996) Screening for genetic predisposition to mutagens in cancer patients. Exp. Gerontol., 31, 267-280.
    • (1996) Exp. Gerontol. , vol.31 , pp. 267-280
    • Gupta, R.S.1    Gupta, R.2    Goldstein, S.3
  • 14
    • 0026315962 scopus 로고
    • Heterogeneity of breast cancer risk in families of young breast cancer patients and controls
    • Schwartz, A.G., Kaufmann, R. and Moll, P.P. (1991) Heterogeneity of breast cancer risk in families of young breast cancer patients and controls. Am. J. Epidemiol., 134, 1325-1334.
    • (1991) Am. J. Epidemiol. , vol.134 , pp. 1325-1334
    • Schwartz, A.G.1    Kaufmann, R.2    Moll, P.P.3
  • 15
    • 0030925921 scopus 로고    scopus 로고
    • Two potential clinical applications of the alkaline single cell gel electrophoresis assay: (1) human bladder washings and transitional cell carcinoma of the bladder; and (2) human sperm and male infertility
    • McKelvey-Martin, Melia, N., Walsh, I.K., Johnston, S.R., Hughes, C.M., Lewin, S.E.M. and Thompson, W. (1997) Two potential clinical applications of the alkaline single cell gel electrophoresis assay: (1) human bladder washings and transitional cell carcinoma of the bladder; and (2) human sperm and male infertility. Mutat. Res., 375, 93-104.
    • (1997) Mutat. Res. , vol.375 , pp. 93-104
    • McKelvey-Martin1    Melia, N.2    Walsh, I.K.3    Johnston, S.R.4    Hughes, C.M.5    Lewin, S.E.M.6    Thompson, W.7
  • 16
    • 0025458633 scopus 로고
    • Chromosomal abnormalities in human breast cancer
    • Mars, W.M. and Saunders, G.F. (1990) Chromosomal abnormalities in human breast cancer. Cancer Metastasis Rev., 9, 35-43.
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 35-43
    • Mars, W.M.1    Saunders, G.F.2
  • 17
    • 0026724578 scopus 로고
    • Cytogenetic damage in peripheral blood lymphocytes of cancer patients prior to radiotherapy
    • Ramesh, K.H. and Bhargava, M.K. (1992) Cytogenetic damage in peripheral blood lymphocytes of cancer patients prior to radiotherapy. Cancer Genet. Cytogenet., 60, 86-88.
    • (1992) Cancer Genet. Cytogenet. , vol.60 , pp. 86-88
    • Ramesh, K.H.1    Bhargava, M.K.2
  • 18
    • 0023272175 scopus 로고
    • Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer
    • Kovacs, E. and Almendral, A. (1987) Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer. Eur. J. Cancer Clin. Oncol., 23, 1051-1057.
    • (1987) Eur. J. Cancer Clin. Oncol. , vol.23 , pp. 1051-1057
    • Kovacs, E.1    Almendral, A.2
  • 20
    • 0026566088 scopus 로고
    • Systemic genotoxic effect to tobacco-related nitrosamines following oral and inhalational administration to Sprague Dawley rats
    • Pool-Zobel, B.L., Brendler, S.Y., Liegibel, U.M., Tompa, A. and Schmezer, P. (1992) Systemic genotoxic effect to tobacco-related nitrosamines following oral and inhalational administration to Sprague Dawley rats. Clin. Invest., 70, 299-306.
    • (1992) Clin. Invest. , vol.70 , pp. 299-306
    • Pool-Zobel, B.L.1    Brendler, S.Y.2    Liegibel, U.M.3    Tompa, A.4    Schmezer, P.5
  • 21
    • 0342940808 scopus 로고    scopus 로고
    • Detection of MNNG-induced DNA lesions in mammalian cells: Validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations
    • Slamenova, D., Gabelova, A., Ruzekova, L., Chalupa, I., Horvathova, E., Farkasova, T., Bozsakyova, E. and Stetina, R. (1997) Detection of MNNG-induced DNA lesions in mammalian cells: validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations. Mutat. Res., 399, 243-252.
    • (1997) Mutat. Res. , vol.399 , pp. 243-252
    • Slamenova, D.1    Gabelova, A.2    Ruzekova, L.3    Chalupa, I.4    Horvathova, E.5    Farkasova, T.6    Bozsakyova, E.7    Stetina, R.8
  • 22
    • 0344624874 scopus 로고    scopus 로고
    • Bleomycin-induced DNA damage and its removal in lymphocytes of breast cancer patients studied by comet assay
    • Jaloszynski, P., Kujawski, M., Czub-Swierczek, M., Markowska, J. and Szyfter, K. (1997) Bleomycin-induced DNA damage and its removal in lymphocytes of breast cancer patients studied by comet assay. Mutat. Res., 385, 223-233.
    • (1997) Mutat. Res. , vol.385 , pp. 223-233
    • Jaloszynski, P.1    Kujawski, M.2    Czub-Swierczek, M.3    Markowska, J.4    Szyfter, K.5
  • 23
    • 0026935108 scopus 로고
    • Losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild type chromosome
    • Smith, A.A., Eston, D.F., Evans, D.G.R. and Ponder, B.A.J. (1992) Losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild type chromosome. Nature Genet., 2, 128-131.
    • (1992) Nature Genet. , vol.2 , pp. 128-131
    • Smith, A.A.1    Eston, D.F.2    Evans, D.G.R.3    Ponder, B.A.J.4
  • 24
    • 0031060263 scopus 로고    scopus 로고
    • Chromosome instability syndromes: Lessons for carcinogenesis
    • Meyn, M.S. (1997) Chromosome instability syndromes: lessons for carcinogenesis. Curr. Topics Microbiol. Immunol., 221, 71-148.
    • (1997) Curr. Topics Microbiol. Immunol. , vol.221 , pp. 71-148
    • Meyn, M.S.1
  • 25
    • 0027749437 scopus 로고
    • Abnormal chromosome repair and risk of developing cancer
    • Au, W.W. (1993) Abnormal chromosome repair and risk of developing cancer. Environ. Health Perspect., 101, 303-308.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 303-308
    • Au, W.W.1
  • 26
    • 0024342809 scopus 로고
    • Factors affecting and significance of G2 chromatin radiosensitivity in predisposition to cancer
    • Sanford, K.K., Parshad, R., Gantt, R., Tarone, R.E., Jones, G.M. and Price, F.M. (1989) Factors affecting and significance of G2 chromatin radiosensitivity in predisposition to cancer. Int. J Radiat. Biol., 55, 963-981.
    • (1989) Int. J Radiat. Biol. , vol.55 , pp. 963-981
    • Sanford, K.K.1    Parshad, R.2    Gantt, R.3    Tarone, R.E.4    Jones, G.M.5    Price, F.M.6
  • 27
    • 0021176251 scopus 로고
    • Age related variation in the DNA repair synthesis after UV-C irradiation in unstimulated lymphocytes of healthy blood donors
    • Kovacs, E., Weber, W. and Muller, H.J. (1984) Age related variation in the DNA repair synthesis after UV-C irradiation in unstimulated lymphocytes of healthy blood donors. Mutat. Res., 131, 231-237.
    • (1984) Mutat. Res. , vol.131 , pp. 231-237
    • Kovacs, E.1    Weber, W.2    Muller, H.J.3
  • 29
    • 0032054436 scopus 로고    scopus 로고
    • Reduced DNA repair capacity in breast cancer patients and unaffected individuals from breast cancer families
    • Rao, N.M., Pai, S.A., Shinde, S.R. and Gosh, S.N. (1998) Reduced DNA repair capacity in breast cancer patients and unaffected individuals from breast cancer families. Cancer Genet. Cytogenet., 102, 65-73.
    • (1998) Cancer Genet. Cytogenet. , vol.102 , pp. 65-73
    • Rao, N.M.1    Pai, S.A.2    Shinde, S.R.3    Gosh, S.N.4
  • 30
    • 0022364961 scopus 로고
    • Evidence for chromosome instability in vivo in Bloom syndrome: Increased numbers of micronuclei in exfoliated cells
    • Rosin, M.P. and German, J. (1985) Evidence for chromosome instability in vivo in Bloom syndrome: increased numbers of micronuclei in exfoliated cells. Hum. Genet., 71, 187-191.
    • (1985) Hum. Genet. , vol.71 , pp. 187-191
    • Rosin, M.P.1    German, J.2
  • 31
    • 0026457889 scopus 로고
    • Heterozygous manifestations in four autosomal recessive human cancer prone syndromes: Ataxia telengiectasia, xeroderma pigmentosum. Fanconi anemia and Bloom syndrome
    • Heim, R.A., Lench, N.J. and Swift, M. (1992) Heterozygous manifestations in four autosomal recessive human cancer prone syndromes: ataxia telengiectasia, xeroderma pigmentosum. Fanconi anemia and Bloom syndrome. Mutat. Res., 284, 25-36.
    • (1992) Mutat. Res. , vol.284 , pp. 25-36
    • Heim, R.A.1    Lench, N.J.2    Swift, M.3
  • 32
    • 0021864535 scopus 로고
    • Differential mutagen susceptibility in cultured lymphocytes of normal individuals and cancer patients
    • Hsu, T.S., Cherry, L.M. and Samaan, N.A. (1985) Differential mutagen susceptibility in cultured lymphocytes of normal individuals and cancer patients. Cancer Genet. Cytogenet, 17, 307-313.
    • (1985) Cancer Genet. Cytogenet , vol.17 , pp. 307-313
    • Hsu, T.S.1    Cherry, L.M.2    Samaan, N.A.3
  • 33
    • 0027215352 scopus 로고
    • X-ray induced chromatid damage in relation to DNA repair and cancer incidence in family members
    • Knight, R.D., Parshad, R., Price, F.M., Tarone, R.E. and Sanford, K.K. (1993) X-ray induced chromatid damage in relation to DNA repair and cancer incidence in family members. Int. J. Cancer, 54, 589-593.
    • (1993) Int. J. Cancer , vol.54 , pp. 589-593
    • Knight, R.D.1    Parshad, R.2    Price, F.M.3    Tarone, R.E.4    Sanford, K.K.5
  • 34
    • 0025087025 scopus 로고
    • Inter-individual variation in chromosome aberration response to treatment with uphidicolin and folate deficiency
    • Saritha, B.T. and Ahuja, Y.R. (1990) Inter-individual variation in chromosome aberration response to treatment with uphidicolin and folate deficiency. Med. Sci. Res., 18, 785-787.
    • (1990) Med. Sci. Res. , vol.18 , pp. 785-787
    • Saritha, B.T.1    Ahuja, Y.R.2
  • 35
    • 0024576760 scopus 로고
    • Cell kinetics and radiation pathology
    • Denekamp, J. and Rojas, A. (1989) Cell kinetics and radiation pathology. Experientia, 45, 33-41.
    • (1989) Experientia , vol.45 , pp. 33-41
    • Denekamp, J.1    Rojas, A.2
  • 36
    • 0025029088 scopus 로고
    • DNA damage and repair following treatment with ionising radiation
    • Powell, S. and McMillan, T.J. (1990) DNA damage and repair following treatment with ionising radiation. Radiother. Oncol., 19, 95-108.
    • (1990) Radiother. Oncol. , vol.19 , pp. 95-108
    • Powell, S.1    McMillan, T.J.2
  • 39
    • 0028986735 scopus 로고
    • O(6)-alkylguanine DNA alkyltransferase activity levels in normal, benign and malignant human female breast
    • Musarrat, J., Wilson, J.A., Abou-Issa, H. and Wani, A.A. (1995) O(6)-alkylguanine DNA alkyltransferase activity levels in normal, benign and malignant human female breast. Biochem. Biophys. Res. Commun., 208, 688-696.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 688-696
    • Musarrat, J.1    Wilson, J.A.2    Abou-Issa, H.3    Wani, A.A.4
  • 40
    • 0343309721 scopus 로고
    • Biology of disease. DNA repair and its pathogenic implications
    • Bohr, V.A., Evans, M.K. and Fornace, A.J.Jr (1989) Biology of disease. DNA repair and its pathogenic implications. Lab. Invest., 50, 945-950.
    • (1989) Lab. Invest. , vol.50 , pp. 945-950
    • Bohr, V.A.1    Evans, M.K.2    Fornace A.J., Jr.3
  • 41
    • 0001543765 scopus 로고
    • Cancer-prone hereditary diseases with DNA processing abnormalities
    • Hanawalt, P. and Sarasin, A. (1986) Cancer-prone hereditary diseases with DNA processing abnormalities. Trends Genet., 2, 124-129.
    • (1986) Trends Genet. , vol.2 , pp. 124-129
    • Hanawalt, P.1    Sarasin, A.2
  • 42
    • 0024348174 scopus 로고
    • DNA repair and cancer: Speculations based on studies with xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy
    • Lehmann, A.R. and Norris, P.G. (1989) DNA repair and cancer: speculations based on studies with xeroderma pigmentosum, Cockayne's syndrome and trichothiodystrophy. Carcinogenesis, 10, 1353-1356.
    • (1989) Carcinogenesis , vol.10 , pp. 1353-1356
    • Lehmann, A.R.1    Norris, P.G.2
  • 43
    • 0342874684 scopus 로고
    • Methods for studying excision repair of eukaryotic DNA damaged by physical and chemical mutagens
    • Kilbey, B.J., Legator, M., Nichols, W. and Ramel, C. (eds) Karger Publishers, Basel, Switzerland
    • Cleaver, J.E. (1984) Methods for studying excision repair of eukaryotic DNA damaged by physical and chemical mutagens. In Kilbey, B.J., Legator, M., Nichols, W. and Ramel, C. (eds) A Laboratory Manual of Research Procedures. Karger Publishers, Basel, Switzerland. Vol. 1, Part B, pp. 403-418.
    • (1984) A Laboratory Manual of Research Procedures , vol.1 , Issue.PART B , pp. 403-418
    • Cleaver, J.E.1
  • 44
    • 0032519766 scopus 로고    scopus 로고
    • Nonconservative aminoacid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans
    • Shen, M.R., Jones, I.M. and Mohrenweiser, H. (1998) Nonconservative aminoacid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res., 58, 604-608.
    • (1998) Cancer Res. , vol.58 , pp. 604-608
    • Shen, M.R.1    Jones, I.M.2    Mohrenweiser, H.3
  • 46
    • 0028242630 scopus 로고
    • Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage
    • Hagmar, L., Brogger, A., Hansteen, I.L., Heim, S., Hogstedt, B., Knudsen, L., Lambert, B., Linnainmaa, K., Mitelman, F., Nordenson, I. et al. (1994) Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage. Cancer Res., 54, 2919-2922.
    • (1994) Cancer Res. , vol.54 , pp. 2919-2922
    • Hagmar, L.1    Brogger, A.2    Hansteen, I.L.3    Heim, S.4    Hogstedt, B.5    Knudsen, L.6    Lambert, B.7    Linnainmaa, K.8    Mitelman, F.9    Nordenson, I.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.