Modulation of GABA(A) receptor subunit mRNA levels in olivocerebellar neurons of Purkinje cell degeneration and weaver mutant mice

Journal of Neurochemistry

Volumn 74, Issue 5, 2000, Pages 2190-2200

  Rotter, A ^a   Rath, S ^a   Evans, J E ^a   Frostholm, A ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Deep cerebellar nuclei; GABA(A); Inferior olive; pcd pcd mice; wv wv mice

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; MESSENGER RNA; RECEPTOR SUBUNIT;

ANIMAL TISSUE; ARTICLE; CEREBELLUM; CEREBELLUM NUCLEUS; EFFERENT NERVE; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; INFERIOR OLIVE; MALE; MOUSE; MOUSE MUTANT; NERVE CELL DEGENERATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; SENSORY NERVE;

ANIMALS; CEREBELLAR NUCLEI; FEMALE; MALE; MICE; MICE, NEUROLOGIC MUTANTS; NERVE DEGENERATION; NEURONS; OLIVARY NUCLEUS; PROTEIN ISOFORMS; PURKINJE CELLS; RECEPTORS, GABA-A; RNA, MESSENGER;

ANIMALIA; EUKARYOTA;

EID: 0034006044     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0742190.x     Document Type: Article

References (74)

1. Alvarado-Mallart R.-M. and Sotelo C. (1993) Cerebellar grafting in murine heredodegenerative ataxia. Current limitations for a therapeutic approach, in Advances in Neurology, Vol. 61: Inherited Ataxias (Harding A. E. and Deufel T., eds), pp. 181-192. Raven Press, New York.
2. Ashwell K. W. S. and Zhang L.-L. (1992) Ontogeny of afferents to the fetal rat cerebellum. Acta Anat. (Basel) 145, 17-23.
3. A receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50, 291-313.
4. A receptor subunit mRNAs in rat cerebellar granule neurons: importance of environmental cues. J. Neurochem. 66, 1347-1353.
5. Blatt G. J. and Eisenman L. M. (1985) A qualitative and quantitative light microscopic study of the inferior olivary complex of normal, weaver and reeler mutant mice. J. Comp. Neurol. 232, 117-128.
6. Bourrat F. and Sotelo C. (1984) Postnatal development of the inferior olivary complex in the rat. III. A morphometric analysis of the volumetric growth and neuronal cell number. Dev. Brain Res. 16, 241-251.
7. A/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J. Comp. Neurol. 356, 615-628.
8. Chen S.-C, Ehrherd P., Goldowitz D., and Smeyne R. (1997) Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse. Brain Res. 778, 251-264.
9. Cherubini E., Gaiursa J. L., and Ben-Ari Y. (1991) GABA: an excilttory transmitter in early postnatal life. Trends Neurosci. 14, 515-519.
10. Chetodal A. and Sotelo C. (1993) The 'creeper stage' in cerebellar climbing fiber synaptogenesis precedes the 'pericellular nest' -ultrastructural evidence with parvalbumin immunocyochemistry. Dev. Brain Res. 76, 207-220.
11. Crepel F. J. (1982) Regression of functional synapses in the immature mammalian cerebellum. Trends Neurosci. 5, 266-270.
12. Crepel F. J., Mariani J., and Delhaye-Bouchaud N. (1976) Evidence for a multiple innervation of Purkinje cells by climbing fibers in the immature rat cerebellum. J. Neurobiol. 7, 567-578.
13. Desclin J. C. (1974) Histological evidence supporting the inferior olive as the major source of cerebellar climbing fibers in the rat. Brain Res. 77, 365-384.
14. De Zeeuw C. I., Van Alphen A. M., Hawkins R. K., and Ruigrok T. J. H. (1997) Climbing fibre collaterals contact neurons in the cerebellar nuclei that provide a GABAergic feedback to the inferior olive. Neuroscience 80, 981-986.
15. Dumesnil-Bousez N. and Sotelo C. (1992) Early development of the lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis. J. Neurocytol. 21, 506-529.
16. Farrant M., Feldmeyer D., Takahashi T., and Cull-Candy S. G. (1994) NMDA-receptor channel diversity in the developing cerebellum. Nature 368, 235-239.
17. Fernandez A. M., Gonzalez de la Vega A., Planas B., and Torres-Aleman I. (1999) Neuroprotective actions of peripherally administered insulin-like growth factor I in the injured olivocerebellar pathway. Eur. J. Neurosci. 11, 2019-2030.
18. Fredette B. J. and Mugnaini E. (1991) The GABAergic cerebello-olivary projection in the rat. Anat. Embryol. (Berl.) 184, 225-243.
19. A-receptor subtypes during postnatal development: an immunohistochemical study. J. Neurosci. 14, 5302-5324.
20. 1 subunit mRNA expression in reeler mouse cerebellar Purkinje cells during postnatal development. Dev. Brain Res. 64, 121-128.
21. 3H]muscimol binding sites. Mol. Brain Res. 16, 246-254.
22. Galli-Resta L. and Resta G. (1992) A quantitative model for the regulation of naturally occurring cell death in the developing vertebrate nervous system. J. Neurosci. 12, 4586-4594.
23. A receptor messenger RNA expression in the deep cerebellar nuclei of Purkinje cell degeneration mutants is maintained following the loss of innervating Purkinje neurons. Neuroscience 52, 63-71.
24. Gardette R., DeBono M., Dupont J.-L., and Crepel F. (1985) Electrophysiological studies on the postnatal development of the intracerebellar nuclei neurons in rat cerebellar slices maintained in vitro. I. Postsynaptic potentials. Dev. Brain Res. 19, 47-55.
25. Ghetti B., Norton J., and Triarhou L. C. (1987) Nerve cell atrophy and loss in the olivary complex of "Purkinje cell degeneration" mutant mice. J. Comp. Neurol. 260, 409-422.
26. Gotow T. and Sotelo C. (1987) Postnatal development of the inferior olivary complex in the rat: IV. Synaptogenesis of GABAergic afferents, analyzed by glutamic acid decarboxylase immunocytochemistry. J. Comp. Neurol. 263, 526-552.
27. Gu Y. and Hall Z. W. (1988) Immunological evidence for a change in subunits of the acetylcholine receptor in developing and denervated rat muscle. Neuron 1, 117-125.
28. A receptor subunits. Mol. Brain Res. 28, 338-342.
29. Heckroth J., Hohart N. J. H., and Summers D. (1998) Transplanted neurons alter the course of neurodegenerative disease in lurcher mutant mice. Exp. Neurol. 154, 336-352.
30. Herrup K. and Trenker E. (1987) Regional differences in cytoarchitecture of the weaver cerebellum suggests a new model for weaver gene action. Neuroscience 23, 871-855.
31. Herrup K., Shojaeian-Zanjani H., Panzini L., Sunter K., and Mariani J. (1996) The numerical matching of source and target populations in the CNS: the inferior olive to Purkinje cell projection. Dev. Brain Res. 96, 28-35.
32. Ike J., Canton H., and Sanders-Bush E. (1995) Developmental switch in the hippocampal serotonin receptor linked to phosphoinositide hydrolysis. Brain Res. 678, 49-54.
33. 6 subunit gene inactivation inhibits δ subunit expression. J. Neurosci. 17, 1350-1362.
34. Kidokoro Y. (1993) Developmental changes of transmitter gated channels. Jpn. J. Physiol. 43, 727-743.
35. A receptor mRNAs and increases ligand binding. J. Neurochem. 61, 2334-2337.
36. + channel and rescue of weaver granule cells. Neuron 16, 941-952.
37. Landis S. C. and Mullen R. J. (1978) The development and degeneration of Purkinje cells in pcd mutant mice. J. Comp. Neurol. 177, 125-144.
38. Larramendi L. M. H. (1969) Analysis of synaptogenesis in the cerebellum of the mouse, in Neurobiology of Cerebellar Evolution and Development (Llinas R., ed), pp. 803-843. American Medical Association Education Research Foundation, Chicago.
39. 2 subunit gene expression in the developing normal and mutant mouse cerebellum. Mol. Brain Res. 19, 9-21.
40. Mariani J. (1982) Extent of multiple innervation of Purkinje cells by climbing fibers in the olivocerebellar system of weaver, reeler and staggerer mutant mice. J. Neurobiol. 13, 119-126.
41. Mariani J., Knopfel T., and Gahwiler B. H. (1991) Co-cultures of inferior olive and cerebellum: electrophysiological evidence for multiple innervation of Purkinje cells by olivary axons. J. Neurobiol. 22, 865-872.
42. Maricich S. M., Soha J., Trenkner E., and Herrup K. (1997) Failed cell migration and death of Purkinje cells and deep nuclear neurons in the weaver cerebellum. J. Neurosci. 17, 3675-3683.
43. Mason C. A. (1987) Development of cerebellar mossy fibers and climbing fibers: embryonic and postnatal features, in New Concepts in Cerebellar Neurobiology (King J. S., ed), pp. 57-88. Alan R. Liss, New York.
44. Mason C. A., Christakos S., and Catalano S. M. (1990) Early climbing fiber interactions with Purkinje cells in the postnatal mouse cerebellum. J. Comp. Neurol. 297, 77-90.
45. Meier E., Belhage B., Drejer J., and Schousboe A. (1987) The expression of GABA receptors on cultured cerebellar granule cells is influenced by GABA, in Neurotrophic Activity of GABA During Development (Redburne D. A. and Schousboe A., eds), pp. 139-159. Alan R. Liss, New York.
46. Mishina M., Takai T., Imoto K., Noda M., Takahashi T., Numa S., Methfessel C., and Sakmann B. (1986) Molecular distinction between fetal and adult forms of muscle acetylcholine receptor. Nature 321, 406-411.
47. Monyer H., Burnashev N., Laurie D. J., Sakmann B., and Seeburg P. H. (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
48. Mullen R. (1977) Site of pcd action and Purkinje cell mosaicism in cerebella of chimaeric mice. Nature 270, 245-247.
49. Mullen R. J., Eicher E. M., and Sidman R. L. (1976) Purkinje cell degeneration, a new neurological mutation in the mouse. Proc. Natl. Acad. Sci. USA 73, 208-212.
50. Mullen R. J., Hamre K. M., and Goldowitz D. (1997) Cerebellar mutant mice and chimeras revisited. Perspect. Dev. Neurobiol. 5, 43-55.
51. Patil N., Cox D. R., Bhat D., Faham M., Myers R. M., and Peterson A. S. (1995) A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat. Genet. 11, 126-129.
52. Patterson P. H. and Nawa H. (1993) Neuronal differentiation factors/cytokines and synaptic plasticity. Neuron 10 (Suppl.), 123-137.
53. Rabacchi S., Bailly Y., Delhaye-Bouchaud N., and Herrup K. (1992) Role of the target in synapse elimination: studies in the cerebellum of developing lurcher, mutants and adult chimeric mice. J. Neurosci. 12, 4712-4720.
54. Rieff H. I., Raetzman L., Sapp D. W., Yen H. H., Siegel R. E., and Corfas G. (1999) Neuregulin induces GABAA receptor subunit expression and neurite outgrowth in cerebellar granule cells. J. Neurosci. 19, 10757-10766.
55. Riva-Depaty I., LeMaigre Dubreuil Y., Mariani J., and Delhaye-Bouchaud N. (1998) Eradication of cerebellar granule cells alters the developmental expression of trk receptors in the rat inferior olive. Int. J. Dev. Neurosci. 16, 49-62.
56. Roffler-Tarlov S., Beart P. M., O'Gorman S., and Sidman R. L. (1979) Neurochemical and morphological consequences of axon terminal degeneration in deep cerebellar nuclei of mice with inherited Purkinje cell degeneration. Brain Res. 168, 75-95.
57. Rossi F., Jankovski A., and Sotelo C. (1995) Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice. J. Neurosci. 15, 2040-2056.
58. Rotter A., Birdsall N. J. M., Burgen A. S. V., Field P. M., and Raisman G. (1977) Axotomy causes loss of muscarinic receptors and loss of synaptic contacts in the hypoglossal nucleus. Nature 266, 734-735.
59. 3H]propylbenzilyl choline mustard and associated synaptic changes in the hypoglossal and pontine nuclei. Brain Res. Rev. 1, 207-224.
60. Rotter A., Schultz C., and Frostholm A. (1984) Regulation of glycine receptor binding in the mouse hypoglossal nucleus in response to axotomy. Brain Res. Bull. 13, 487-492.
61. Schwartz-Levey M., Brumwell C. L., Dryer S. E., and Jacob M. H. (1995) Innervation and target tissue interactions differentially regulate acetylcholine receptor subunit mRNA levels in developing neurons in situ. Neuron 14, 153-162.
62. Sheng M., Cummings J., Roldan L. A., Jan Y. N., and Jan L. Y. (1994) Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368, 144-147.
63. Shojaeian H., Delhaye-Bouchaud N., and Mariani J. (1985) Neuronal death and synapse elimination in the olivocerebellar system: II. Cell counts in the inferior olive of adult X-irradiated rats and weaver and reeler mutant mice. J. Comp. Neurol. 232, 309-318.
64. Shojaeian H., Delhaye-Bouchaud N., and Mariani J. (1988) Stability of inferior olivary neurons in rodents. I. Moderate cell loss in adult Purkinje cell degeneration mutant mouse. Dev. Brain Res. 38, 211-218.
65. Shojaeian-Zanjani H., Mariani J., and Herrup K. (1990) Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene. J. Neurogenet. 6, 229-241.
66. Sotelo C., Gotow T., and Wassef M. (1986) Localization of glutamic acid decarboxylase-immunoreactive axon terminals in the inferior olive of the rat, with special emphasis on anatomical relations between GABAergic synapses and dendritic gap junctions. J. Comp. Neurol. 252, 32-50.
67. Takahashi T., Momiyama A., Hirai K., Hishinuma F., and Akagi H. (1992) Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels. Neuron 9, 1155-1161.
68. Triarhou L. C. and Ghetti B. (1991) Stabilization of neurone number in the inferior olivary complex of aged 'Purkinje cell degeneration' mutant mice. Acta Neuropathol. (Berl.) 81, 597-602.
69. Vogel M. W., McInnes M., Zanjani H. S., and Herrup K. (1991) Cerebellar Purkinje cells provide target support over a limited spatial range: evidence from lurcher mice. Dev. Brain Res. 64, 87-94.
70. Wassef M., Simons J., Tappaz M. L., and Sotelo C. (1986) Non-Purkinje cell GABAergic innervation of the deep cerebellar nuclei: a quantitative immunocytochemical study in C57BL and in Purkinje cell degeneration mutant mice. Brain Res. 399, 125-135.
71. Wetts R. and Herrup K. (1982) Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimaeric mice. I. Qualitative studies. J. Embryol. Exp. Morphol. 68, 87-98.
72. Wolff J. R., Joó F., and Kasa P. (1993) Modulation by GABA of neuroplasticity in the central and peripheral nervous system. Neurochem. Res. 18, 453-461.
73. 3H]flunitrazepam binding sites during postnatal development of the mouse cerebellum. Dev. Brain Res. 61, 63-71.
74. 3 subunit mRNAs in the developing mouse cerebellum. J. Comp. Neurol. 326, 580-594.