Synthesis of benzimidazole derivatives as antiallergic agents with 5- lipoxygenase inhibiting action

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 11, 1999, Pages 1573-1578

  Nakano, Hiroyuki ^a   Inoue, Tsutomu ^a   Kawasaki, Nobuhide ^b   Miyataka, Hideki ^b   Matsumoto, Hitoshi ^b   Taguchi, Takeo ^c   Inagaki, Naoki ^d   Nagai, Hiroichi ^d   Satoh, Toshio ^b  

^a Fuji Yakuhin Co Ltd   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

5 lipoxygenase; Antiallergic agent; Antioxidative action; Benzimidazole; Histamine

Indexed keywords

1 [2 [2 (4 HYDROXY 2,3,5 TRIMETHYLPHENOXY)ETHOXY]ETHYL] 2 (4 METHYL 1 HOMOPIPERAZINO)BENZIMIDAZOLE; ANTIALLERGIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; BENZIMIDAZOLE DERIVATIVE; HISTAMINE; LIPOXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; GUINEA PIG; HISTAMINE RELEASE; ILEUM; LIPID PEROXIDATION; LIVER MICROSOME; MALE; NONHUMAN; PERITONEUM MAST CELL; RAT; SMOOTH MUSCLE RELAXATION;

EID: 0033428686     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1573     Document Type: Article

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