Characterization, chromosomal localization, and the complete 30-kb DNA sequence of the human Jagged2 (JAG2) gene

Genomics

Volumn 63, Issue 1, 2000, Pages 133-138

  Deng, Yu ^a   Madan, Anup ^a   Banta, Amy B ^a   Friedman, Cynthia ^a   Trask, Barbara J ^a   Hood, Leroy ^a   Li, Linheng ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ADULT; ARTICLE; BINDING SITE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 14Q; DNA SEQUENCE; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE ISOLATION; GENE MAPPING; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS;

EID: 0034005166     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.6045     Document Type: Article

References (54)

1. Artavanis-Tsakonas S., Matsuno K., Fortini M. E. Notch signaling. Science. 268:1995;225-232.
2. Artavanis-Tsakonas S., Simpson P. Choosing cell fate: A view from the Notch locus. Trends Genet. 7:1991;403-408.
3. Artavanis-Tsakonas S., Rand M. D., Lake R. J. Notch signaling: Cell fate control and signal integration in development. Science. 284:1999;770-776.
4. Baker N. E., Mlodzik M., Rubin G. M. Spacing differentiation in the Drosophila eye: A fibrinogen-related lateral inhibitor encoded by scabrous. Science. 250:1990;1270-1377.
5. Bettenhausen B., de Angelis M. H., Simon D., Guenet J. L., Gossler A. Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development. 121:1995;2407-2418.
6. Birnstiel M. L., Busslinger M., Strub K. Transcription termination and 3′ processing: The end is in site. Cell. 41:1985;349-359.
7. Coffman C. R., Harris W., Kinter C. Xotch, the Xenopus homolog of Drosophila Notch. Science. 249:1990;1438-1441.
8. Cuoso J. P., Martinez-Arias A. Notch is required for wingless signaling in the epiderm differentiation. Cell. 67:1994;311-323.
9. Ellisen L. W., Bird J., West D. C., Soreng A. L., Reynolds T. C., Smith S. D., Sklar J. TAN-1, the human homolog of Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell. 66:1991;649-661.
10. Ewing B., Hillier L., Wendl M., Green P. Basecalling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8:1998;175-185.
11. Ewing B., Green P. Basecalling of automated sequencer traces using phred. II. Error probabilities. Genome Res. 8:1998;186-194.
12. Fortini M. E., Artavanis-Tsakonas S. Notch: Neurogenesis is only part of the picture. Cell. 75:1993;1245-1247.
13. Franco del Amo F., Smith D. E., Swiatek P. J., Gendron-Maguire M., Greenspan R. J., McMahon A. P., Gridley T. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 115:1992;737-744.
14. Gordon D., Abajian C., Green P. Consed: A graphical tool for sequence finishing. Genome Res. 8:1998;195-202.
15. Greenwald I. Structure/function studies of lin-12/Notch proteins. Curr. Opin. Genet. Dev. 4:1994;556-562.
16. Greenwald I., Rubin G. M. Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells. Cell. 68:1992;271-281.
17. Gruneberg H. Genetic studies on the skeleton of the mouse XXIX. Genet. Res. 2:1961;384-393.
18. Hamada Y., Kadokawa Y., Okabe M., Ikawa M., Coleman J. R., Tsujimoto Y. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development. 126:1999;3415-3424.
19. Hrabe de Angelis M. M. J. N., Gossler A. Maintenance of somite borders in mice requires the Delta homologue DII1. Nature. 386:1997;717-721.
20. Hunkapiller T., Kaiser R. J., Koop B. F., Hood L. Large-scale and automated DNA sequence determination. Science. 254:1991;59-67.
21. Jhappan C., Gallahan D., Stahle C., Chu E., Smith G. H., Merline G., Callahan R. Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev. 6:1992;345-355.
22. Jiang R., Lan Y., Chapman H. D., Schawber C., Norton R., Serreze D. V., Weinmaster G., Gridley T. Defects in limb, craniofacial, and thymic development in JAG2 mutant mice. Genes Dev. 12:1998;1046-1057.
23. Joutel A., Corpechot C., Ducros A., Vahedi K., Chabriat H., Mouton P., Alamowitch S., Domenga V., Cecillion M., Marechal E., Maciazak J., Vayssiere C., Cruaud C., Cabanis E. A., Ruchoux M. N., Weissenbach J., Bach J. F., Bousser M. G., Tournier-Lasserve E. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature. 383:1996;707-710.
24. Kimble J., Simpson P. The Lin-12/Notch signaling pathway and its regulation. Annu. Rev. Cell. Dev. Biol. 13:1997;333-361.
25. Kopan R., Cagan R. Notch on the cutting edge. Trends Genet. 13:1997;465-467.
26. Kopan R., Weintraub H. Mouse Notch: Expression in hair follicles correlates with cell fate determination. J. Cell Biol. 121:1993;631-641.
27. Kusumi K. S. E., Kerrebrock A. W., Bronson R. T., Chi D. C., Bulotsky M. S., Spencer J. B., Birren B. W., Frankel W. N., Lander E. S. The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nat. Genet. 19:1998;274-278.
28. Lanford P. J., Lan Y., Jiang R., Lindsell C., Weinmaster G., Gridley T., Kelley M. W. Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat. Genet. 21:1999;289-292.
29. Lardeli M., Dahlstrand J., Lendahl U. The novel Notch homolog mouse Notch3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech. Dev. 46:1994;123-136.
30. Li L., Huang G., Banta A., Deng Y., Friedman C., Trask B., Rowen L., Hood L. Cloning, characterization, and the complete 57-kilobase DNA sequence of the human Notch4 gene. Genomics. 51:1998a;45-58.
31. Li L., Krantz I. D., Deng Y., Genin A., Banta A., Collins C., Qi M., Trask B. J., Kuo W., Cochran J., Costa T., Ella M., Pierpont M., Rand E., Piccoli D., Hood L., Spinner N. Alagille syndrome is caused by mutations in JAG1 (JAG1), which encodes a ligand for Notch1. Nat. Genet. 16:1997;243-251.
32. Li L., Milner L., Deng Y., Iwata M., Banta A., Graf L., Marcovina S., Friedman C., Trask B., Hood L., Torok-Storb B. Human homolog of rat JAG1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity. 8:1998b;43-55.
33. Lindsell C. E., Shawber C. J., Boulter J., Weinmaster G. JAG: A mammalian ligand that activates Notch1. Cell. 80:1995;909-917.
34. Luo B., Aster J. C., Hasser J. R. P., Kuo F., Sklar J. Isolation and functional analysis of a cDNA for human JAG2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17:1997;6057-6067.
35. Muskavitch M. A. T., Hoffman F. M. Homologs of vertebrate growth factors in Drosophila melanogaster and other vertebrates. Curr. Top. Dev. Biol. 24:1990;289-328.
36. Myat A., Henrique D., Ish-Horowicz, Lewis J. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev. Biol. 174:1996;233-247.
37. Oda T., Elkahloun A. G., Pike B. L., Okajima K., Krantz I. D., Genin A., Piccoli D. A., Meltzer P. S., Spinner N. B., Collins F. S., Chandrasekharappa S. C. Mutations in the human JAG1 gene are responsible for Alagille syndrome. Nat. Genet. 16:1997;235-242.
38. Reaume A. G., Conlon R. A., Zirngibl R., Yamaguchi T. P., Rossant J. Expression analysis of a Notch homologue in the mouse embryo. Dev. Biol. 154:1992;377-387.
39. Robbins J., Blondel B. J., Gallahan D., Callahan R. Mouse mammary tumor gene int-3, a member of the Notch gene family transforms mammary epithelial cells. J. Virol. 66:1992;2594-2599.
40. Rowen L., Koop B. F. Zen and the art of large-scale genomic sequencing. Adams M. D., Fields C., Venter J. C. Automated DNA Sequencing and Analysis. 1994;167-174 Academic Press, San Diego.
41. Shawber C. J., Boulter J., Lindsell C. E., Weinmaster G. JAG2: A Serrate-like gene expressed during rat embryogenesis. Dev. Biol. 180:1996;370-376.
42. Sidow A., Bulotsky M. S., Kerrebrock A. W., Bronson R. T., Daly M. J., Reeve M. P., Hawkins T. L., Birren B. W., Jaenisch R., Lander E. S. Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature. 389:1997;722-725.
43. Smith T. M., Lee M. K., Szabo C. I., Jerome N., McEuen M., Taylor M., Hood L., King M-C. Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res. 6:1996;1029-1049.
44. Swiatek P. J., Linfsell C. E., Del Amo F. F., Weinmaster G., Gridley T. Notch1 is essential for postimplantation development in mice. Genes Dev. 8:1994;707-719.
45. Trask B. J. Fluorescence in situ hybridization. Birren B., Green E., Heiter P., Klapholz S., Myers R., Reithman H., Roskams J. Genome Analysis: A Laboratory Manual. 1999;303-413 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
46. Trask B. J., Massa H. F., Brand-Arpon V., Chan K., Friedman C., Nguyen O. T., Eichler E., Van den Engh G., Rouquier S., Shizuya H., Giorgi D. Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome. Hum. Mol. Genet. 7:1998;2007-2020.
47. Uyttendaele H., Marazzi G., Wu G., Yan Q., Sassoon D., Kitajewski J. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development. 122:1996;2251-2259.
48. Weinmaster G. Notch signaling: Direct or what. Curr. Opin. Genet. Dev. 8:1998;436-442.
49. Weinmaster G., Roberts V. J., Lemke G. A homolog of Drosophila Notch expressed during mammalian development. Development. 113:1991;199-205.
50. Weinmaster G., Roberts V. J., Lemke G. Notch2: A second mammalian Notch gene. Development. 116:1992;931-941.
51. Xu Y., Mural R. J., Uberbacher E. C. Constructing gene models from accurately predicted exons: An application of dynamic programming. Comput. Appl. Biosci. 10:1994;613-623.
52. Xue Y., Gao X., Lindsell C. E., Norton C. R., Chang B., Hicks C., Gendron-Maguire M., Rand E. B., Weinmaster G., Gridley T. Embryonic lethality and vascular defects in mice lacking the notch ligand jagged1. Hum. Mol. Genet. 8:1999;723-730.
53. Yochen J., Greenwald I. glp-1 and lin-12, genes implicated in distal cell-cell interactions in C. elegans, encodes similar transmembrane proteins. Cell. 58:1989;553-563.
54. Zimier A. B., Pepper M., McMahon G. A., Nguyen F., Montesano R., Maciag T. An antisense oligonucleotide to the Notch ligand JAG enhances fibroblast growth factor-induced angiogenesis in vitro. J. Biochem. 211:1996;32499-32502.