H-NS is a repressor of the Proteus mirabilis urease transcriptional activator gene ureR

Journal of Bacteriology

Volumn 182, Issue 9, 2000, Pages 2649-2653

  Coker, Christopher ^a   Bakare, Olubunmi O ^a   Mobley, Harry L T ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE;

ARTICLE; BINDING SITE; DNA SEQUENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEUS MIRABILIS; REPRESSOR GENE; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; DNA-BINDING PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; POLY A; PROMOTER REGIONS (GENETICS); PROTEUS MIRABILIS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; UREASE;

ESCHERICHIA COLI; MIRABILIS; NEGIBACTERIA; PROKARYOTA; PROTEUS MIRABILIS;

EID: 0034002290     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.9.2649-2653.2000     Document Type: Article

References (38)

1. Atlung, T., and H. Ingmer. 1997. H-NS: a modulator of environmentally regulated gene expression. Mol. Microbiol. 24:7-17.
2. Braud, A. I., and J. Siemienski. 1960. Role of bacterial urease in experimental pyelonephritis. J. Bacteriol. 80:171-179.
3. D'Orazio, S. E. F., V. Thomas, and C. M. Collins. 1996. Activation of transcription at divergent urea-dependent promoters by the urease gene regulator UreR. Mol. Microbiol. 21:643-655.
4. D'Orazio, S. E. F., and C. M. Collins. 1995. UreR activates transcription at multiple promoters within the plasmid-encoded urease locus of the Enterobacteriaceae. Mol. Microbiol. 21:145-155.
5. D'Orazio, S. E. F., and C. M. Collins. 1993. The plasmid-encoded urease gene cluster of the Enterobacteriaceae is positively regulated by UreR, a member of the AraC family of transcriptional regulators. J. Bacteriol. 175: 3459-3467.
6. Fletcher, S. A., and L. N. Csonka. 1995. Fine-structure deletion analysis of the transcriptional silencer of the proU operon of Salmonella typhimurium. J. Bacteriol. 177:4508-4513.
7. Gorril, R. H. 1965. The fate of Pseudomonas aeruginosa, Proteus mirabilis, and Escherichia coli in the mouse kidney. J. Pathol. Bacteriol. 89:81-88.
8. Griffith, D. P., D. M. Musher, and C. Itin. 1976. Urease: the primary cause of infection-induced urinary stones. Investig. Urol. 13:346-350.
9. Griffith, D. P. 1979. Urease stones. Urol. Res. 7:215-221.
10. Hamilton-Miller, J. M. T., and R. A. Gargan. 1979. Rapid screening for urease inhibitors. Investig. Urol. 16:327-328.
11. Island, M. D., and H. L. T. Mobley. 1995. Proteus mirabilis urease: operon fusion and linker insertion analysis of ure gene organization, regulation, and function. J. Bacteriol. 177:5653-5660.
12. Jones, B. D., C. V. Lockatell, D. E. Johnson, J. W. Warren, and H. L. T. Mobley. 1990. Construction of a urease-negative mutant of Proteus mirabilis: analysis of virulence in a mouse model of ascending urinary tract infection. Infect. Immun. 58:1120-1123.
13. Jones, B. D., and H. L. T. Mobley. 1988. Proteus mirabilis urease: genetic organization, regulation, and expression of structural genes. J. Bacteriol. 170: 3342-3349.
14. Jones, B. D., and H. L. T. Mobley. 1987. Genetic and biochemical diversity of ureases of Proteus, Providencia, and Morganella species isolated from urinary tract infection. Infect. Immun. 55:2198-2203.
15. Jordi, B. J. A. M., B. Dagberg, L. A. M. de Haan, A. M. Hamers, V. A. M. van der Zeijst, W. Gaastra, and B. E. Uhlin. 1992. The positive regulator CfaD overcomes the repression mediated by histone-like protein H-NS (H1) in the CFA/I fimbrial operon of Escherichia coli. EMBO J. 11:2627-2632.
16. Koo, H. S., H. M. Wu, and D. M. Crothers. 1986. DNA bending at adeninethymine tracts. Nature 320:501-506.
17. La Teana, A., M. Falconi, V. Scarletto, M. Lammi, and C. L. Pon. 1989. Characterization of the structural genes for the DNA-binding protein H-NS in Enterobacteriaceae. FEBS Lett. 244:34-38.
18. Lucht, J. M., P. Dersch, B. Kempf, and E. Bremer. 1994. Interactions of the nucleoid-associated DNA binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli. J. Biol. Chem. 269:6578-6586.
19. Maniatis, T., E. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Maurelli, A. T., and P. J. Sansonetti. 1988. Identification of a chromosomal gene controlling temperature-regulated expression of Shigella virulence. Proc. Natl. Acad. Sci. USA 85:2820-2824.
21. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
22. Mobley, H. L. T., M. D. Island, and R. P. Hausinger. 1995. Molecular biology of microbial ureases. Microbiol. Rev. 59:451-480.
23. Mobley, H. L. T., and J. W. Warren. 1987. Urease-positive bacteriuria and obstruction of long-term urinary catheters. J. Clin. Microbiol. 25:2216-2217.
24. Mobley, H. L. T., B. D. Jones, and A. E. Jerse. 1986. Cloning of urease gene sequences from Providencia stuartii. Infect, Immun. 54:161-169.
25. Murphree, D., B. Froehlich, and J. R. Scott. 1997. Transcriptional control of genes encoding CS1 pili: negative regulation by a silencer and positive regulation by Rns. J. Bacteriol. 179:5736-5743.
26. Nicholson, E. B., E. A. Concaugh, P. A. Foxall, M. D. Island, and H. L. T. Mobley. 1993. Proteus mirabilis urease: transcriptional regulation by ureR. J. Bacteriol. 175:465-473.
27. Owen-Hughes, T. A., G. D. Pavitt, D. S. Santos, J. M. Sidebotham, C. S. J. Hulton, J. C. D. Hinton, and C. F. Higgens. 1992. The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Cell 71:255-265.
28. Reeder, T., and R. Scleif. 1993. AraC protein can activate transcription from only one position and when pointed in only one direction. J. Mol. Biol. 231: 205-218.
29. Rosenstein, I., J. M. T. Hamilton-Miller, and W. Brumfitt. 1980. The effect of acetohydroxamic acid on the induction of bacterial ureases. Investig. Urol. 18:112-114.
30. Sanger, R., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
31. Shapira, S. K., J. Chou, F. V. Richard, and M. J. Casadaban. 1983. New and versatile plasmid vectors for expression of hybrid proteins coded by a cloned gene fused to lacZ gene sequences encoding an enzymatically active carboxyterminal portion of β-galactosidase. Gene. 25:71-82.
32. Silhavey, T. J., M. L. Berman, and L. W. Enquist. 1984. Experiments with gene fusions. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
33. Simons, R. W., F. Houman, and N. Kleckner. 1987. Improved single and multicopy lar-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
34. Thomas, V. J., and C. M. Collins. 1999. Identification of UreR binding sites in the Enterobacteriaceae plasmid-encoded and Proteus mirabilis urease gene operons. Mol. Microbiol. 31:1417-1428.
35. Tobe, T., M. Yoshikawa, T. Mizuno, and C. Sasakawa. 1993. Transcriptional control of the invasion regulatory gene virB of Shigella flexneri: activation by VirF and repression by H-NS. J. Bacteriol. 175:6142-6149.
36. Wang, R. F., and S. R. Kushner. 1991. Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli. Gene. 100:195-199.
37. Yamada, H., T. Yoshida, K. I. Tanaka, C. Sasakawa, and T. Mizuno. 1991. Molecular analysis of the Escherichia coli hns gene encoding a DNA-binding protein which preferentially recognizes curved DNA sequences. Mol. Gen. Genet. 230:332-336.
38. Zhang, A., S. Rimsky, M. E. Reaben, H. Buc, and M. Belfort. 1996. Escherichia coli protein analogs StpA and H-NS: regulatory loops, similar and disparate effects on nucleic acid dynamics. EMBO J. 15:1340-1349.