-
1
-
-
0026800606
-
Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation and evolution
-
Aharonowitz, Y., Cohen, G., and Martin, J.F. 1992. Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation and evolution. Annu. Rev. Microbiol. 46: 461-495.
-
(1992)
Annu. Rev. Microbiol.
, vol.46
, pp. 461-495
-
-
Aharonowitz, Y.1
Cohen, G.2
Martin, J.F.3
-
2
-
-
0023996141
-
The biosynthesis of penicillins and cephalosporins
-
Baldwin, J.E., and Abraham, E.P. 1988. The biosynthesis of penicillins and cephalosporins. Nat. Prod. Rep. 5: 129-145.
-
(1988)
Nat. Prod. Rep.
, vol.5
, pp. 129-145
-
-
Baldwin, J.E.1
Abraham, E.P.2
-
4
-
-
0023180606
-
Purification and characterization of cloned isopenicillin N synthase
-
Baldwin, J.E., Killin, S.J., Patt, A.J., Sutherland, J.D., Turner, N.J., Crabbe, M.J.C., Abraham, E.P., and Willis, A.C. 1987. Purification and characterization of cloned isopenicillin N synthase. J. Antibiot. 40: 652-659.
-
(1987)
J. Antibiot.
, vol.40
, pp. 652-659
-
-
Baldwin, J.E.1
Killin, S.J.2
Patt, A.J.3
Sutherland, J.D.4
Turner, N.J.5
Crabbe, M.J.C.6
Abraham, E.P.7
Willis, A.C.8
-
5
-
-
0030032150
-
Ferrous active site of Isopenicillin N synthase: Genetic and sequence analysis of the endogenous ligands
-
Borovok, I., Landman, O., Kreisberg-Zakarin, R., Aharonowitz, Y., and Cohen, G. 1996. Ferrous active site of Isopenicillin N synthase: Genetic and sequence analysis of the endogenous ligands. Biochemistry, 35: 1981-1987.
-
(1996)
Biochemistry
, vol.35
, pp. 1981-1987
-
-
Borovok, I.1
Landman, O.2
Kreisberg-Zakarin, R.3
Aharonowitz, Y.4
Cohen, G.5
-
6
-
-
0029998881
-
Purification and characterization of recombinant Streptomyces clavuligerus isopenicillin N synthase produced in Escherichia coli
-
Durairaj, M., and Jensen, S.E. 1996. Purification and characterization of recombinant Streptomyces clavuligerus isopenicillin N synthase produced in Escherichia coli. J. Ind. Microbiol. 16: 197-203.
-
(1996)
J. Ind. Microbiol.
, vol.16
, pp. 197-203
-
-
Durairaj, M.1
Jensen, S.E.2
-
7
-
-
0003728297
-
-
John Innes Foundation, Norwich
-
Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith, C.P., and Shrempf, H. 1985. Genetic manipulation of Streptomyces : a Laboratory Manual. John Innes Foundation, Norwich.
-
(1985)
Genetic Manipulation of Streptomyces : A Laboratory Manual
-
-
Hopwood, D.A.1
Bibb, M.J.2
Chater, K.F.3
Kieser, T.4
Bruton, C.J.5
Kieser, H.M.6
Lydiate, D.J.7
Smith, C.P.8
Shrempf, H.9
-
8
-
-
0030444264
-
Engineering antibiotic producers to overcome the limitations of classical strain improvement programme
-
Lal, R., Khanna, R., Kaur, H., Khanna, M., Dhingra, N., Lal, S., Gartermann, K.-H., Eichenlaub, R., and Ghosh, P.K. 1996. Engineering antibiotic producers to overcome the limitations of classical strain improvement programme. Crit. Rev. Microbiol. 22: 201-255.
-
(1996)
Crit. Rev. Microbiol.
, vol.22
, pp. 201-255
-
-
Lal, R.1
Khanna, R.2
Kaur, H.3
Khanna, M.4
Dhingra, N.5
Lal, S.6
Gartermann, K.-H.7
Eichenlaub, R.8
Ghosh, P.K.9
-
9
-
-
0023649836
-
High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12
-
Levinson, G., and Gutman, G.A. 1987. High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12. Nucleic Acids Res. 15: 5323-5338.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 5323-5338
-
-
Levinson, G.1
Gutman, G.A.2
-
10
-
-
0031408344
-
Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium Isopenicillin N synthase
-
Loke, P., Sim, J., and Sim, T.S. 1997. Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium Isopenicillin N synthase. FEMS Microbiol. Lett. 157: 137-140.
-
(1997)
FEMS Microbiol. Lett.
, vol.157
, pp. 137-140
-
-
Loke, P.1
Sim, J.2
Sim, T.S.3
-
11
-
-
0024375676
-
Cloning and characterization of beta-lactam biosynthetic genes
-
Miller, J.R., and Ingolia, T.D. 1989. Cloning and characterization of beta-lactam biosynthetic genes. Mol. Microbiol. 3: 689-695.
-
(1989)
Mol. Microbiol.
, vol.3
, pp. 689-695
-
-
Miller, J.R.1
Ingolia, T.D.2
-
12
-
-
0015211523
-
Beta-lactam antibiotics from streptomycetes
-
Nagarajan, R., Boeck, L.D., Gorman, M., Hamill, R.L., Higgens, C.E., Hoehn, M.M., Stark, W.M., and Whitney, J.G. 1971. Beta-lactam antibiotics from streptomycetes. J. Am. Chem. Soc. 93: 2308-2310.
-
(1971)
J. Am. Chem. Soc.
, vol.93
, pp. 2308-2310
-
-
Nagarajan, R.1
Boeck, L.D.2
Gorman, M.3
Hamill, R.L.4
Higgens, C.E.5
Hoehn, M.M.6
Stark, W.M.7
Whitney, J.G.8
-
13
-
-
0029038392
-
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes
-
Roach, P.L., Clifton, I.J., Fulop, V., Harlos, K., Barton, G.J., Hadju, J., Anderson, I., Schofield, C.J., and Baldwin, J.E. 1995. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature, 375: 700-704.
-
(1995)
Nature
, vol.375
, pp. 700-704
-
-
Roach, P.L.1
Clifton, I.J.2
Fulop, V.3
Harlos, K.4
Barton, G.J.5
Hadju, J.6
Anderson, I.7
Schofield, C.J.8
Baldwin, J.E.9
-
14
-
-
0024116545
-
Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces
-
Shiffman, D., Mevarech, M., Jensen, S.E., Cohen, G., and Aharonowitz, Y. 1988. Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces. Mol. Gen. Genet. 214: 562-569.
-
(1988)
Mol. Gen. Genet.
, vol.214
, pp. 562-569
-
-
Shiffman, D.1
Mevarech, M.2
Jensen, S.E.3
Cohen, G.4
Aharonowitz, Y.5
-
15
-
-
0029552707
-
Biophysical factors affecting the expression of isopenicillin N synthase isozymes in Escherichia coli
-
Sim, T.S., and Tan, S.H.D. 1995. Biophysical factors affecting the expression of isopenicillin N synthase isozymes in Escherichia coli. Biochem. Mol. Biol. Internl. 35: 1069-1078.
-
(1995)
Biochem. Mol. Biol. Internl.
, vol.35
, pp. 1069-1078
-
-
Sim, T.S.1
Tan, S.H.D.2
-
16
-
-
0030569495
-
Production of high levels of soluble recombinant Streptomyces clavuligerus isopenicillin N synthase in Escherichia coli
-
Sim, B.J., Tan, D.S.H., Liu, X., and Sim, T.S. 1996. Production of high levels of soluble recombinant Streptomyces clavuligerus isopenicillin N synthase in Escherichia coli. J. Mol. Catal. B: Enzym. 2: 71-83.
-
(1996)
J. Mol. Catal. B: Enzym.
, vol.2
, pp. 71-83
-
-
Sim, B.J.1
Tan, D.S.H.2
Liu, X.3
Sim, T.S.4
-
17
-
-
0030025142
-
Functional analysis of conserved histidine residues in Cephalosporium acremonium Isopenicillin N synthase by site-directed mutagenesis
-
Tan, S.H.D., and Sim, T.S. 1996. Functional analysis of conserved histidine residues in Cephalosporium acremonium Isopenicillin N synthase by site-directed mutagenesis. J. Biol. Chem. 271: 889-894.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 889-894
-
-
Tan, S.H.D.1
Sim, T.S.2
-
18
-
-
0027968068
-
CLUSTAL w: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice
-
Thompson, J.D., Higgins, D.G., and Gibson, T.J. 1994. CLUSTAL w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22: 4673-4680.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
19
-
-
0024590380
-
δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans - The 1st enzyme in penicillin biosynthesis is a multifunctional peptide synthetase
-
Van Liempt, H., Von Dohren, H., and Klienkauf, H. 1989. δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans - the 1st enzyme in penicillin biosynthesis is a multifunctional peptide synthetase. J. Biol. Chem. 264: 3860-3864.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 3860-3864
-
-
Van Liempt, H.1
Von Dohren, H.2
Klienkauf, H.3
-
20
-
-
0023774770
-
Cloning and expression in Escherichia coli of Isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans
-
Weigel, J., Burgett, S.G., Chen, V.J., Skatrud, P.L., Frolik, C.A., Queener, S.W., and Ingolia, T.D. 1988. Cloning and expression in Escherichia coli of Isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans. J. Bacteriol. 170: 3817-3826.
-
(1988)
J. Bacteriol.
, vol.170
, pp. 3817-3826
-
-
Weigel, J.1
Burgett, S.G.2
Chen, V.J.3
Skatrud, P.L.4
Frolik, C.A.5
Queener, S.W.6
Ingolia, T.D.7
-
21
-
-
0023184331
-
Bacterial evolution
-
Woese, C.R. 1987. Bacterial evolution. Microbiol. Rev. 51: 2211-2271.
-
(1987)
Microbiol. Rev.
, vol.51
, pp. 2211-2271
-
-
Woese, C.R.1
|