Pharmacological effects of novel quinone compounds, 6-(fluorinated- phenyl)amino-5,8-quinolinediones, on inhibition of drug-induced relaxation of rat aorta and their putative action mechanism

General Pharmacology

Volumn 34, Issue 1, 2000, Pages 33-42

  Lee, Jung Ah ^a   Jung, Sung Hee ^a   Bae, Mee Kyung ^a   Ryu, Chung Kyu ^a   Lee, Joo Young ^b   Chung, Jin Ho ^b   Kim, Hwa Jung ^a  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Acetylcholine; Endothelium; Lipopolysaccharide; OQ1; OQ21; Quinones; Sodium nitroprusside; Superoxide; Vasorelaxation

Indexed keywords

6 (2,3,4 TRIFLUOROPHENYL)AMINO 5,8 QUINOLINEDIONE; 6 (4 FLUOROPHENYL)AMINO 5,8 QUINOLINEDIONE; 6 ANILINO 5,8 QUINOLINEQUINONE; ACETYLCHOLINE; ARGININE; BENZOQUINONE DERIVATIVE; CYCLIC GMP; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; OQ 1; OQ 21; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTERY DILATATION; ARTICLE; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYLCHOLINE; AMINOQUINOLINES; ANIMALS; AORTA; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VASODILATION; VASODILATOR AGENTS;

EID: 0033994146     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(00)00044-6     Document Type: Article

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