Antigen-presenting cells recruited by Brugia malayi induce Th2 differentiation of naive CD4+ T cells

European Journal of Immunology

Volumn 30, Issue 4, 2000, Pages 1127-1135

  Loke, P'ng ^a   MacDonald, Andrew S ^a,b   Allen, Judith E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

Antigen presenting cell; Helminth; Macrophage; Naive T cell; Transforming growth factor

Indexed keywords

CARBOXYFLUORESCEIN; CD4 ANTIGEN; CYTOCHROME C; CYTOKINE ANTIBODY; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; BRUGIA MALAYI; CONTROLLED STUDY; CYTOKINE PRODUCTION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; PARASITE IMMUNITY; PERITONEAL EXUDATE CELL; PIGEON; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH2 CELL; TRANSGENIC MOUSE;

EID: 0033993917     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-4141(200004)30:4<1127::aid-immu1127>3.0.co;2-%23     Document Type: Article

References (44)

1. O'Garra, A., Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 1998. 8:275-283.
2. Abbas, A. K., Murphy, K. M. and Sher, A., Functional diversity of helper T lymphocytes. Nature 1996. 383:787-793.
3. Sabin, E. A., Kopf, M. A. and Pearce, E. J., Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils. J. Exp. Med. 1996. 184:1871-1878.
4. Osborne, J. and Devaney, E., The L3 of Brugia induces a Th2-polarized response following activation of an IL-4-producing CD4-CD8-αβ T cell population. Int. Immunol. 1998. 10:1583-1590.
5. + T cell responses: the alternative approaches. Annu. Rev. Immunol. 1997. 15:297-322.
6. Goerdt, S. and Orfanos, C. E., Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 1999. 10:137-142.
7. Rissoan, M. C., Soumelis, V., Kadowaki, N., Grouard, G., Briere, F., Malefyt, R. D. and Liu, Y. J., Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999. 283:1183-1186.
8. Maizels, R. M., Bundy, D. A. P., Selkirk, M. E., Smith, D. F. and Anderson, R. M., Immunological modulation and evasion by helminth parasites in human populations. Nature 1993. 365:797-805.
9. Piesens, W. F., McGreevy, P. B., Piessens, P. W., McGreevy, M., Koiman, I., Saroso, J. S. and Dennis, D. T., Immune responses in human infections with Brugia malayi. Specific cellular unresponsiveness to filarial antigens. J. Clin. Invest. 1980. 65:172-179.
10. Yazdanbakhsh, M., Paxton, W. A., Kruize, Y. C. M., Sartono, E., Kurniawan, A., van het Wout, A., Selkirk, M. E., Partono, F. and Maizels, R. M., T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis. J. Infect. Dis. 1993. 167:925-931.
11. Allen, J. E., Lawrence, R. A. and Maizels, R. M., APC from mice harboring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int. Immunol. 1996. 8:143-151.
12. MacDonald, A. S., Maizels, R. M., Lawrence, R. A., Dransfield, I. and Allen, J. E., Requirement for in vivo production of IL-4, but not IL-10, in the production of proliferative suppression by filarial parasites. J. Immunol. 1998. 160:4124-4132.
13. Beverly, B., Kang, S. M., Lenardo, M. J. and Schwartz, R. H., Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Int. Ilmmunol. 1992. 4:661-671.
14. Jenkins, M. K., The role of cell division in the induction of clonal anergy. Immunol. Today 1992. 13:69-73.
15. Powell, J. D., Lerner, C. G. and Schwartz, R. H., Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation. J. Immunol. 1999. 162:2775-2784.
16. Harding, F. A., McArthur, J. G., Gross, J. A., Raulet, D. H. and Allison, J. P., CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T cell clones. Nature 1992. 356:607-609.
17. Hayashi, R. J., Loh, D. Y., Kanagawa, O. and Wang, F. P., Differences between responses of naive and activated T cells to anergy induction. J. Immunol. 1998. 160:33-38.
18. + T cells from T cell receptor transgenic mice. J. Exp. Med. 1992. 176:1091-1098.
19. Stockinger, B., Zal, T., Zal, A. and Gray, D., B cells solicit their own help from T cells. J. Exp. Med. 1996. 183:891-899.
20. Takeuchi, M., Alard, P. and Streilein, J. W., TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells. J. Immunol. 1998. 160:1589-1597.
21. Bird, J. J., Brown, D. R., Mullen, A. C., Moskowitz, N. H., Mahowald, M. A., Sider, J. R., Gajewski, T. F., Wang, C. R. and Reiner, S. L., Helper T cell differentiation is controlled by the cell cycle. Immunity 1998. 9:229-237.
22. Gett, A. V. and Hodgkin, P. D., Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl. Acad. Sci. USA 1998. 95:9488-9493.
23. Cua, D. J. and Stohlman, S. A., In vivo effects of T helper cell type 2 cytokines on macrophage antigen-presenting cell induction of T helper subsets. J. Immunol. 1997. 159:5834-5840.
24. Armant, M., Avice, M. N., Hermann, P., Rubio, M., Kiniwa, M., Delespesse, G. and Sarfati, M., CD47 ligation selectively down-regulates human interleukin 12 production. J. Exp. Med. 1999. 190:1175-1182.
25. Sutterwala, F. S., Noel, G. J., Clynes, R. and Mosser, D. M., Selective suppression of interleukin-12 induction after macrophage receptor ligation. J. Exp. Med. 1997. 185:1977-1985.
26. Osborne, J. and Devaney, E., Interleukin-10 and antigen-presenting cells actively suppress Th1 cells in BALB/c mice infected with the filarial parasite Brugia pahangi. Infect. Immun. 1999. 67:1599-1605.
27. Iwasaki, A. and Kelsall, B. L., Freshly isolated Payer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 1999. 190:229-239.
28. + T cells requires the coordinate action of interleukin-12 and interferon-γ and is inhibited by transforming growth factor-β. Eur. J. Immunol. 1994. 24:793-798.
29. Howard, M. and Ogarra, A., Biological properties of interleukin-10. Immunol. Today 1992. 13:198-200.
30. Letterio, J. J. and Roberts, A. B., Regulation of the immune response by TGF-β. Annu. Rev. Immunol. 1998. 16:137-161.
31. Stumbles, P. A., Thomas, J. A., Pimm, C. L., Lee, P. T., Venaille, T. J., Proksch, S. and Holt, P. G., Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J. Exp. Med. 1998. 188:2019-2031.
32. King, C., Davies, J., Mueller, R., Lee, M. S., Krahl, T., Yeung, B., O'Connor, E. and Sarvetnick, N., TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype. Immunity 1998. 8:601-613.
33. Gorham, J. D., Güler, M. L., Fenoglio, D., Gubler, U. and Murphy, K. M., Low dose TGF-β attenuates IL-12 responsiveness in murine Th2 cells. J. Immunol. 1998. 161:1664-1670.
34. Barral-Netto, M., Barral, A., Brownell, C. E., Skeiky, Y. A. W., Ellingsworth, L. R., Twardzik, D. R. and Reed, S. G., Transforming growth factor β in leishmanial infection: a parasite escape mechanism. Science 1992. 257:545-548.
35. Nagelkerken, L., Gollob, K. J., Tielemans, M. and Coffman, R. L., Role of transforming growth factor-beta in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B. Eur. J. Immunol. 1993. 23:2306-2310.
36. Swain, S. L., Huston, G., Tonkonogy, S. and Weinberg, A., Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 1991. 147:2991-3000.
37. Sad, S. and Mosmann, T. R., Single IL-2 secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J. Immunol. 1994. 153:3514-3522.
38. Lingnau, K., Hoehn, P., Kerdine, S., Koelsch, S., Neudoerfl, C., Palm, N., Ruede, E. and Schmitt, E., IL-4 in combination with TGF-beta favors an alternative pathway of Th1 development independent of IL-12. J. Immunol. 1998. 161:4709-4718.
39. + T cells isolated from different mouse strains. J. Immunol. 1995. 155:3788-3793.
40. Takeuchi, M., Kosiewicz, M. M., Alard, P. and Streilein, J. W., On the mechanisms by which transforming growth factor-beta 2 alters antigen-presenting abilities of macrophages on T cell activation. Eur. J. Immunol. 1997. 27:1648-1656.
41. Desmedt, M., Rottiers, P., Dooms, H., Fiers, W. and Grooten, J., Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses. J. Immunol. 1998. 160:5300-5308.
42. Horowitz, J. B., Kaye, J., Conrad, P. J., Katz, M. E. and Janeway, C. A. Jr., Autocrine growth inhibition of a cloned line of helper T cells. Proc. Natl. Acad. Sci. USA 1986. 83:1886-1890.
43. Dasch, J. R., Pace, D. R., Waegell, W., Inenaga, D. and Ellingsworth, L., Monoclonal antibodies recognizing transforming growth factor-β. Bioactivity neutralization and transforming growth factor β2 affinity purification. J. Immunol. 1989. 142:1536-1541.
44. Lyons, A. B. and Parish, C. R., Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 1994. 171:131-137.