Interaction between the bHLH-PAS protein Trachealess and the POU-domain protein Drifter, specifies tracheal cell fates

Mechanisms of Development

Volumn 91, Issue 1-2, 2000, Pages 163-173

  Zelzer, Elazar ^a   Shilo, Ben Zion ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

bHLH; Drifter; Drosophila; PAS; POU; Tracheal development; Trachealess

Indexed keywords

DNA BINDING PROTEIN; HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CELL FATE; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION; GENE INDUCTION; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRACHEA;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; POU DOMAIN FACTORS; TRACHEA; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0033993558     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(99)00295-6     Document Type: Article

References (47)

1. Ambrosetti D.C., Basilico C., Dailey L. Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol. Cell Biol. 17:1997;6321-6329.
2. Anderson M.G., Perkins G.L., Chittick P., Shrigley R.J., Johnson W.A. drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia. Genes Dev. 9:1995;123-137.
3. Anderson M.G., Certel S.J., Certel K., Lee T., Montell D.J., Johnson W.A. Function of the Drosophila POU domain transcription factor Drifter as an upstream regulator of breathless receptor tyrosine kinase expression in developing trachea. Development. 122:1996;4169-4178.
4. Bacon N.C., Wappner P., O'Rourke J.F., Bartlett S.M., Shilo B., Pugh C.W., Ratcliffe P.J. Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha. Biochem. Biophys. Res. Commun. 249:1998;811-816.
5. Bier E., Jan L.Y., Jan Y.N. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev. 4:1990;190-203.
6. Bonini N.M., Bui Q.T., Gray-Board G.L., Warrick J.M. The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates. Development. 124:1997;4819-4826.
7. Burbach K.M., Poland A., Bradfield C.A. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl. Acad. Sci. USA. 89:1992;8185-8189.
8. Certel K., Anderson M.G., Shrigley R.J., Johnson W.A. Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea. Mol. Cell Biol. 16:1996;1813-1823.
9. Damert A., Ikeda E., Risau W. Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells. Biochem. J. 327:1997;419-423.
10. de Celis J.F., Llimargas M., Casanova J. ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster. Development. 121:1995;3405-3416.
11. Ema M., Morita M., Ikawa S., Tanaka M., Matsuda Y., Gotoh O., Saijoh Y., Fujii H., Hamada H., Kikuchi Y., Fujii-Kuriyama Y. Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis. Mol. Cell Biol. 16:1996;5865-5875.
12. Ema M., Taya S., Yokotani N., Sogawa K., Matsuda Y., Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxia- inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc. Natl. Acad. Sci. USA. 94:1997;4273-4278.
13. Golembo M., Raz E., Shilo B.-Z. The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development. 122:1996;3363-3370.
14. Gstaiger M., Georgiev O., van Leeuwen H., van der Vliet P., Schaffner W. The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J. 15:1996;2781-2790.
15. Gu Y.Z., Moran S.M., Hogenesch J.B., Wartman L., Bradfield C.A. Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit. HIF3alpha. Gene Expr. 7:1998;205-213.
16. Halder G., Callaerts P., Flister S., Walldorf U., Kloter U., Gehring W.J. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development. 125:1998;2181-2191.
17. Hogenesch J.B., Chan W.K., Jackiw V.H., Brown R.C., Gu Y.Z., Pray-Grant M., Perdew G.H., Bradfield C.A. Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J. Biol. Chem. 272:1997;8581-8593.
18. Huang Z.J., Edery I., Rosbash M. PAS is a dimerization domain common to Drosophila period and several transcription factors. Nature. 364:1993;259-262.
19. Ip Y.T., Park R.E., Kosman D., Bier E., Levine M. The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes Dev. 6:1992;1728-1739.
20. Isaac D.D., Andrew D. Tubulogenesis in Drosophila: a requirement for the trachealess gene product. Genes Dev. 10:1996;103-117.
21. King D.P., Zhao Y., Sangoram A.M., Wilsbacher L.D., Tanaka M., Antoch M.P., Steeves T.D., Vitaterna M.H., Kornhauser J.M., Lowrey P.L., Turek F.W., Takahashi J.S. Positional cloning of the mouse circadian clock gene. Cell. 89:1997;641-653.
22. Lindebro M.C., Poellinger L., Whitelaw M.L. Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex. EMBO J. 14:1995;3528-3539.
23. Llimargas M., Casanova J. Ventral veinless, a POU domain transcription factor, regulates different transduction pathways required for tracheal branching in Drosophila. Development. 124:1997;3273-3281.
24. Maxwell P.H., Pugh C.W., Ratcliffe P.J. Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism. Proc. Natl. Acad. Sci. USA. 90:1993;2423-2427.
25. Michaud J.L., Rosenquist T., May N.R., Fan C.M. Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. Genes Dev. 12:1998;3264-3275.
26. Nambu J.R., Franks R.G., Hu S., Crews S.T. The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell. 63:1990;63-75.
27. Nambu J.R., Lewis J.O., Wharton J.K.A., Crews S.T. The Drosophila single-minded Gene encodes a Helix-Loop-Helix Protein that acts as a Master Regulator of CNS Midline Development. Cell. 67:1991;1157-1167.
28. Nambu J.R., Chen W., Hu S., Crews S.T. The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1 alpha and Drosophila single-minded. Gene. 172:1996;249-254.
29. Ohshiro T., Saigo K. Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea. Development. 124:1997;3975-3986.
30. Probst M.R., Fan C.M., Tessier-Lavigne M., Hankinson O. Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein. J. Biol. Chem. 272:1997;4451-4457.
31. Ryan A.K., Rosenfeld M.G. POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev. 11:1997;1207-1225.
32. Schweitzer R., Shaharabany M., Seger R., Shilo B.-Z. Secreted spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9:1995;1518-1529.
33. Sonnenfeld M., Ward M., Nystrom G., Mosher J., Stahl S., Crews S. The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. Development. 124:1997;4571-4582.
34. Soriano N.S., Russell S. The Drosophila SOX-domain protein Dichaete is required for the development of the central nervous system midline. Development. 125:1998;3989-3996.
35. Tian H., McKnight S.L., Russell D.W. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 11:1997;72-82.
36. Tian H., Hammer R.E., Matsumoto A.M., Russell D.W., McKnight S.L. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev. 12:1998;3320-3324.
37. Turner E.E. Similar DNA recognition properties of alternatively spliced Drosophila POU factors. Proc. Natl. Acad. Sci. USA. 93:1996;15097-15101.
38. Wang G.L., Semenza G.L. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc. Natl. Acad. Sci. USA. 90:1993;4304-4308.
39. 2 tension. Proc. Natl. Acad. Sci. USA. 92:1995;5510-5514.
40. Wappner P., Gabay L., Shilo B.-Z. Interactions between the EGF receptor and Dpp pathways establish distinct cell fates in the tracheal placodes. Development. 124:1997;4707-4716.
41. Ward M., Mosher J., Crews S. Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis. Development. 125:1998;1599-1608.
42. Wharton K.A. Jr, Crews S.T. CNS midline enhancers of the Drosophila slit and Toll genes. Mech. Dev. 40:1993;141-154.
43. Wharton K.A., Franks R.G., Kasai Y., Crews S.T. Control of CNS midline transcription by asymetric E-box-like elements: similarity to xenobiotic responsive regulation. Development. 120:1994;3563-3569.
44. Wilk R., Weizman I., Shilo B.-Z. trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila. Genes Dev. 10:1996;93-102.
45. Zelzer E., Wappner P., Shilo B.-Z. The PAS domain confers target-gene specificity of Drosophila bHLH/PAS proteins. Genes Dev. 11:1997;2079-2089.
46. Zelzer E., Levy Y., Kahana C., Shilo B.-Z., Rubinstein M., Cohen B. Insulin induces transcription of target genes through the hypoxia- inducible factor HIF-1alpha/ARNT. EMBO J. 17:1998;5085-5094.
47. Zhou L., Xiao H., Nambu J.R. CNS midline to mesoderm signaling in Drosophila. Mech. Dev. 67:1997;59-68.