Distribution of ABL and BCR genes in cell nuclei of normal and irradiated lymphocytes

Blood

Volumn 89, Issue 12, 1997, Pages 4537-4545

  Kozubek, S ^a   Lukasova E ^b   Ryznar L ^b   Kozubek, M ^b   Liskova A ^b   Govorun, R D ^b   Krasavin, E A ^b   Horneck, G ^b  

^a INSTITUTE OF MATHEMATICS   (Czech Republic)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE G1 PHASE; CELL NUCLEUS; CELLULAR DISTRIBUTION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE INSERTION; GENE MUTATION; GENE REARRANGEMENT; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INTERPHASE; IRRADIATION; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL;

EID: 1842404178     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.12.4537     Document Type: Article

References (42)

1. Rabbitts TH: Chromosomal translocations in human cancer. Nature 372:143, 1994
2. Pui CH, Crist WM, Look AT: Biology and clinical significance of cytogenic abnormalities in childhood acute lymphoblastic leukemia. Blood 76:1449, 1990
3. Melo JV: The molecular biology of chronic myeloid leukaemia. Leukemia 10:751, 1996
4. Kurzrock R, Gutterman JL, Talkpaz M: The molecular genetics of Philadelphia chromosome-positive leukemias. N Engl J Med 319:990, 1988
5. Ben-Neriah Z, Daley GQ, Mes-Masson AM, Witte ON, Baltimore D: The chronic myelogenous leukemia-specific P210 protein is the product of the bcr-abl hybrid gene. Science 233:212, 1986
6. Groffen J, Stephenson JR, Heisterkamp N, de Klein A, Bartram CR, Grosveld G: Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 36:93, 1984
7. Gishizky ML, Witte ON: Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro. Science 256:836, 1992
8. Daley GQ, VanEtten RA, Baltimore D: Induction of chronic myelogenous leukemia in mice by the P210 bcr-abl gene of the Philadelphia chromosome. Science 247:824, 1990
9. 2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents. Blood 86:1148, 1995
10. Heisterkamp N, Groffen J: Molecular insight into the Philadelphia translocation. Hematol Pathol 5:1, 1991
11. Preston DL, Kusumi S, Tomonaga M, Izumi S, Ron E, Kuramoto A, Kamada N, Dohy H, Matsui T, Nonaka H, Thompson DE, Soda M, Mabuchi K: Cancer incidence in atomic bomb survivors. Part III: Leukemia, lymphoma and multiple myeloma, 1950-1987. Radiat Res 137:S68, 1994
12. Ito T: Induction of BCR-ABL fusion genes by in vitro Xirradiation. Jpn J Cancer Res 84:105, 1995
13. Nelson WG, Pienta KJ, Barrack ER, Coffey DS: The role of nuclear matrix in the organization and function of DNA. Annu Rev Biophys Chem 15:457, 1986
14. Laemmli UK, Kas E, Poljak L, Adachi Y: Scaffold-associated regions: cis-acting determinants of chromatin sructural loops and functional domains. Curr Opin Genet Dev 2:275, 1992
15. Garrard WT: Chromosomal loop organization in eucaryotic genomes, in Eckstein F, Lilley DM (eds): Nucleic Acids Molecular Biology. Heidelberg, Germany, Springer-Verlag, 1990, p 163
16. Lichter P, Cremer T, Borden J, Manuelidis L, Ward DC: Delineation of individual human chromosomes in metaphase and interphase cells by in situ hybridization using recombinant DNA libraries. Hum Genet 80:304, 1988
17. Manuelidis L: A view of interphase chromosomes. Science 250:1533, 1990
18. Haaf T, Schmid M: Chromosome topology in mammalian interphase nuclei. Exp Cell Res 192:325, 1990
19. Hochstrasser M, Sedat JW: Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and regulation. J Cell Biol 104:1471, 1987
20. Fox MH, Arndt-Jovin DJ, Jovin TM, Baumann PH, Robert-Nicaud M: Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts. J Cell Sci 99:247, 1991
21. Höfers C, Baumann P, Hummer G, Jovin TM, Amdt-Jovin DJ: The localization of chromosome domains in human interphase nuclei. Three-dimensional distance determinations of fluorescence in situ hybridization signals from confocal laser scanning microscopy. Bioimaging 1:96, 1993
22. Popp S, Scholl HP, Loos P, Jauch A, Stelzer E, Cremer C, Cremer T: Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells. Exp Cell Res 189:1, 1990
23. De Boni V, Mintz AH: Curvilinear, three-dimensional motion of chromatin domains and nucleoli in neuronal interphase nuclei. Science 14:863, 1986
24. Bartholdi MF: Nuclear distribution of centromeres during the cell cycle of human diploid fibroblasts. J Cell Sci 99:255, 1991
25. Höfers C, Jovin TM, Hummer G, Arndt-Jovin DJ: The localization of chromosome domains in human interphase nuclei. Semiautomated two-dimensional image acquisition and analysis of fluorescence in situ hybridization signals. Bioimaging 1:107, 1993
26. Taniwaki M, Nishida K, Ueda Y, Misawa S, Nagai M, Tagawa S, Yamagami T, Sugiyama H, Abe M, Fukuhura S, Kashima K: Interphase and metaphase detection of the breakpoint of 14q32 translocations in B cell malignancies by double-color fluorescence in situ hybridization. Blood 85:3223, 1995
27. Height SE, Swansbury GJ, Matutes E, Treleaven JG, Catovsky D, Dyer MJS: Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia. Blood 87:5242, 1996
28. Davi F, Gocke F, Smith S, Sklar J: Lymphocytic progenitor cell origin and clonal evolution of human B-lineage acute lymphoblastic leukemia. Blood 88:609, 1996
29. Strachman T, Read AP: Somatic mutations and cancer, in Human Molecular Genetics. Oxford, UK, BIOS Scientific, 1996, p 457
30. Dernburg AF, Broman KW, Fung JC, Marshall WF, Philips J, Agard DA, Sedat JW: Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 85:745, 1996
31. 1 and early S phase in human lymphocytes. Hum Genet 88:673, 1992
32. Lichter P, Cremer T: Chromosome analysis by non-isotopic in situ hybridization, in Rooney DE, Czepulkowski BH (eds): Human Cytogenetics - A Practical Approach, Vol I. Oxford, UK, IRL, 1992, p 157
33. Kozubek M: Analysis of images obtained by fluorescence in situ hybridization. MSc thesis. Brno, Czech Republic, Masaryk University, 1995
34. Serra J: Image Analysis and Mathematical Morphology, Vol I. London, UK, Academic, 1994
35. Lukášová E, Kozubek S, Kozubek M, Kjeronská J, Rýznar L, Horáková J, Krahulcová E, Horneck G: Localization and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukemia. Hum Genet (in press)
36. Natarajan AT: Mechanisms for induction of mutations and chromosome alterations. Environ Health Persp Suppl 101:225, 1993
37. Goodhead DT: Radiation tracks in biological materials: Initial damage in cells, DNA and associated structures, in Mendelson ML (ed): Genes, Cancer and Radiation Protection. Bethesda, MD, National Council on Radiation Protection and Measurements, 1992, p 25
38. Van Zeeland AA: DNA repair, in Obe G (ed): Mutations in Man. Berlin, Germany, Springer-Verlag, 1980, p 35
39. Goodhead DT, Thacker J, Cox R: Effects of radiations of different qualities on cells: Molecular mechanisms of damage and repair. Int J Radiat Biol 63:543, 1993
40. Simpson PJ, Savage JRK: Estimating the true frequency of X-ray-induced complex chromosome exchanges using fluorescence in situ hybridization. Int J Radiat Biol 67:37, 1995
41. Malyapa RS, Wright WD, Roti JLR: Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese hamster cell lines. Radiat Res 140:312, 1994
42. Woudstra EC, Roesink JM, Rosemann M, Brunsting JF, Driessen C, Orta R, Konings AWT, Peacock JH, Kampinga HH: Chromatin structure and cellular radiosensitivity: A comparison of two human tumour cell lines. Int J Radiat Biol 70:693, 1996