Large T-antigen double hexamers imaged at the simian virus 40 origin of replication

Molecular and Cellular Biology

Volumn 20, Issue 1, 2000, Pages 34-41

  Valle, Mikel ^a   Gruss, Claudia ^b   Halmer, Lothar ^b   Carazo, José M ^a   Donate, Luis Enrique ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; VIRUS LARGE T ANTIGEN;

ARTICLE; DNA BINDING; ELECTRON MICROSCOPY; IMAGE PROCESSING; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN STRUCTURE; SIMIAN VIRUS 40; STRUCTURE ANALYSIS; VIRUS REPLICATION;

ANIMALIA; DNA VIRUSES; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0033988190     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.1.34-41.2000     Document Type: Article

References (34)

1. Arthur, A. K., A. Höss, and E. Fanning. 1998. Expression of simian virus 40 T antigen in Escherichia coli: localization of T-antigen origin DNA-binding domain to within 129 amino acids. J. Virol. 62:2204-2208.
2. Borowiec, J. A., and J. Hurwitz. 1998. ATP stimulates the binding of simian virus 40 (SV40) large tumour antigen to the SV40 origin of replication. Proc. Natl. Acad. Sci. USA 85:64-68.
3. Borowiec, J. A., F. B. Dean, P. A. Bullock, and J. Hurwitz. 1990. Binding and unwinding. How T antigen engages the SV40 origin of DNA replication. Cell 60:181-184.
4. Braithwaite, A., H. Stürzbeches, C. Addison, C. Palmer, K. Rudge, and J. R. Jenkins. 1987. Mouse p53 inhibits SV40 origin-dependent DNA replication. Nature 329:458-460.
5. Dean, F. B., M. Dodson, H. Echols, and J. Hurwitz. 1987. ATP-dependent formation of a specialized nucleoprotein structure by simian virus 40 (SV40) large tumor antigen at the replication origin. Proc. Natl. Acad. Sci. USA 84:8981-8985.
6. Dean, F. B., and J. Hurwitz. 1991. Simian virus 40 large T antigen untwist DNA at the origin of DNA replication. J. Biol. Chem. 266:5062-5071.
7. Dean, F. B., J. A. Borowiec, T. Eki, and J. Hurwitz. 1992. The simian virus T antigen double hexamer assembles around the DNA at replication origin. J. Biol. Chem. 267:14129-14137.
8. Deb, S., A. L. De Lucía, C.-P. Banr, A. Koff, and P. Tegtmeyer. 1986. Domain structure of the simian virus 40 core origin of replication. Mol. Cell. Biol. 6:1663-1670.
9. De Caprio, J. A., J. W. Ludlow, J. Figge, J. Y. Shew, C. M. Huang, W. H. Lee, E. Marsillo, E. Pancha, and D. M. Livingston. 1988. SV40 large tumour antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54:275-283.
10. De Lucia, A. L., S. Deb, K. Partin, and P. Tegtmeyer. 1986. Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J. Virol. 57:138-144.
11. Dodson, M., F. B. Dean, P. Bullock, H. Echols, and J. Hurwitz. 1987. Unwinding of duplex DNA from the SV40 origin of replication by T antigen. Science 238:964-967.
12. Fanning, E., and R. Knippers. 1992. Structure and function of simian virus 40 large tumour antigen. Annu. Rev. Biochem. 61:55-85.
13. Gurney, E. G., R. O. Harrison, and J. Fenno. 1980. Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct subclasses of large T antigens and for similarities among nonviral T antigens. J. Virol. 34:752-763.
14. Gurney, E. G., D. Tamowsky, and W. Deppert. 1986. Antigenic binding sites of monoclonal antibodies specific for simian virus large T antigen. J. Virol. 57:1168-1172.
15. Joo, W. S., X. Luo, D. Dennis, H. Y. Kim, G. J. Rainey, C. Jones, K. R. Sreekumar, and P. A. Bullock. 1997. Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin. J. Virol. 71:3972-3985.
16. Joo, W. S., H. Y. Kim, J. D. Purviance, K. R. Sreekumar, and P. A. Bullock. 1998. Assembly of T-antigen double hexamers on the simian virus 40 core origin requires only a subset of the available binding sites. Mol. Cell. Biol. 18:2677-2687.
17. Kohonen, T. 1990. The self-organizing map. Proc. IEEE 78:1464-1480.
18. Lewine, A. J. 1992. The DNA tumour viruses, p. 87-111. In Viruses. Scientific American Library, New York, N.Y.
19. Li, J. J., and T. J. Kelly. 1985. Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication. Mol. Cell. Biol. 11:2108-2115.
20. Li, J. J., K. W. C. Peden, R. A. F. Dixon, and T. Kelly. 1986. Functional organization of the simian virus 40 origin of DNA replication. Mol. Cell. Biol. 6:1117-1128.
21. Luo, X., D. G. Sanford, P. A. Bullock, and W. W. Bachovchin. 1996 Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat. Struct. Biol. 3:1034-1039.
22. Marabini, R., and J. M. Carazo. 1994. Pattern recognition and classification of images of biological macromolecules using artificial neural networks. Biophys. J. 66:1804-1814.
23. Marabini, R., I. M. Masegosa, M. C. San Martín, S. Marco, J. J. Fernández, L. G. de la Fraga, C. Vaquerizo, and J. M. Carazo. 1996. XMIPP: an image processing package for electron microscopy. J. Struct. Biol. 116:237-240.
24. Marco, S., M. Chagoyen, L. G. de la Fraga, J. M. Carazo, and J. L. Carrascosa. 1996. A variant to the random approximation of the reference-free alignment algorithm. Ultramicroscopy 66:5-10.
25. Mastrangelo, I. A., P. V. C. Hough, J. S. Wall, M. Dodson, F. B. Dean, and J. Hurwitz. 1989. ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature 338:658-662.
26. Mastrangelo, I. A., M. Bezanilla, P. K. Hansma, P. V. C. Hough, and H. G. Hanstna. 1994. Structures of large T antigen at the origin of SV40 DNA replication by atomic force microscopy. Biophys. J. 66:293-298.
27. Mole, S. E., J. V. Gannon, M. J. Ford, and D. P. Lane. 1987. Structure and function of large T antigen. Philos. Trans. R. Soc. Lond. Ser. B 317:455-469.
28. Penzeck, P., M. Radermacher, and J. Frank. 1992. Three-dimensional reconstructions of single particle embedded in ice. Ultramicroscopy 40:33-53.
29. San Martín, M. C., C. Gruss, and J. M. Carazo. 1997. Six molecules of SV40 large T antigen assemble in a propeller-shaped particle around a channel. J. Mol. Biol. 268:15-20.
30. Simanis, V., and D. P. Lane. 1985. An immunoaffinity purification procedure for SV40 large tumour antigen. Virology 144:88-100.
31. Tsurimoto, T., T. Melendy, and B. Stillman. 1990. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 346:534-539.
32. Unser, M., B. Trus, and A. C. Steven. 1987. A new resolution criterion based on spectral signal-to-noise ratios. Ultramicroscopy 23:39-52.
33. Weisshart, K., P. Taneja, A. Jenne, U. Herbig, D. T. Simmons, and E. Fanning. 1999. Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. J. Virol. 73:2201-2211.
34. Wessel, R., J. Schweizer, and H. Stahl. 1992. Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication. J. Virol. 66:804-815.