Effects of iron salts and haemosiderin from a thalassaemia patient on oxygen radical damage as measured in the Comet assay

Teratogenesis Carcinogenesis and Mutagenesis

Volumn 20, Issue 1, 2000, Pages 11-26

  Anderson, D ^a,c   Yardley Jones, A ^a   Hambly, R J ^a   Vives Bauza, C ^a   Smykatz Kloss, V ^a   Chua Anusorn, W ^b   Webb, J ^a  

^a BIBRA INTERNATIONAL   (United Kingdom)

^b MURDOCH UNIVERSITY   (Australia)

^c TNO BIBRA International Ltd   (United Kingdom)

Author keywords

Chelating agents; Free radical damage; Haemoglobin synthesis; Haemosiderin; Iron overload; Thalassaemia

Indexed keywords

CHELATING AGENT; DEFEROXAMINE; FERRIC CHLORIDE; FERROUS CHLORIDE; FERROUS SULFATE; FREE RADICAL; HEMOSIDERIN; HYDROGEN PEROXIDE; IRON CHELATE; IRON SALT; OXYGEN RADICAL;

ARTICLE; CASE REPORT; CELL STRAIN CACO 2; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IRON OVERLOAD; LYMPHOCYTE; MALE; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; THALASSEMIA;

CACO-2 CELLS; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FERRIC COMPOUNDS; FERROUS COMPOUNDS; HEMOSIDERIN; HUMANS; HYDROGEN PEROXIDE; IRON COMPOUNDS; LYMPHOCYTES; MALE; REACTIVE OXYGEN SPECIES; THALASSEMIA;

EID: 0033987968     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6866(2000)20:1<11::AID-TCM2>3.0.CO;2-1     Document Type: Article

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