α subunit isoform influences GABA(A) receptor modulation by propofol

Neuropharmacology

Volumn 36, Issue 7, 1997, Pages 941-949

  Krasowski, M D ^a   O'Shea, S M ^a   Rick, C E M ^a   Whiting, P J ^b   Hadingham, K L ^b   Czajkowski, C ^c   Harrison, N L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Merck Sharp & Dohme Limited   (United Kingdom)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Anesthesia; GABA; GABA(A) receptor; Methohexital; Propofol; Trichloroethanol

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ION CHANNEL; METHOHEXITAL; MUSCIMOL; PROPOFOL; RECEPTOR SUBTYPE; TRICHLOROETHANOL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; FIBROBLAST CULTURE; ION CURRENT; MODULATION; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

ANESTHETICS, INTRAVENOUS; ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLENE CHLOROHYDRIN; METHOHEXITAL; MICE; MUSCIMOL; PATCH-CLAMP TECHNIQUES; PROPOFOL; RECEPTORS, GABA-A; STEREOISOMERISM;

EID: 0030839059     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00074-9     Document Type: Article

References (41)

1. Breimer D. D. (1977) Clinical pharmacokinetics of hypnotics. Clinical Pharmacokinetics 2: 93-109.
2. A receptor subtypes: from pharmacology to molecular biology. FASEB Journal 5: 2916-2923.
3. A receptors. Journal of Pharmacology and Experimental Therapeutics 272: 438-445.
4. Franks N. P. and Lieb W. R. (1994) Molecular and cellular mechanisms of general anaesthesia. Nature 367: 607-614.
5. Gage P. W. and Robertson B. (1985) Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane, and ketamine in CA1 pyramidal cells in rat hippocampus. British Journal of Pharmacology 85: 675-681.
6. Garrett E. R. and Lambert H. J. (1973) Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters. Journal of Pharmaceutical Science 62: 550-572.
7. Hadingham K. L., Harkness P. C., McKernan R. M., Quirk K., Le Bourdelles B., Home A., Kemp J. A., Barnard E. A., Ragan C. I. and Whiting P. J. (1992) Stable expression of mammalian type A γ-aminobutyric acid receptors in mouse cells: demonstration of functional assembly of benzodiazepine-responsive sites. Proceedings of the National Academy of Sciences of the U.S.A. 89: 6378-6382.
8. Hales T. G. and Lambert J. J. (1991) The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. British Journal of Pharmacology 104: 619-628.
9. A and glycine receptors by chlormethiazole. European Journal of Pharmacology 210: 239-246.
10. A response in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 81: 988-994.
11. Harrison N. L. and Simmonds M. A. (1984) Modulation of the GABA receptor complex by a steroid anaesthetic. Brain Research 323: 287-292.
12. A receptor complex. Journal of Pharmacology and Experimental Therapeutics 241: 346-353.
13. A receptor activation. British Journal of Pharmacology 108: 711-716.
14. - currents in cultured rat hippocampal neurones by three volatile anesthetics. Journal of Physiology 449: 279-293.
15. A receptor by propofol is independent of the y subunit. Journal of Pharmacology and Experimental Therapeutics 274: 962-968.
16. A receptor α subunit is expressed only in cerebellar granule cells. Journal of Molecular Biology 214: 619-624.
17. Kleingoor C., Wieland H. A., Korpi E. R., Seeburg P. H. and Kettenmann H. L. (1993) Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue. Neuroreport 4: 187-190.
18. A/glycine receptors: expression and barbiturate pharmacology. Neuropharmacology 35: 1445-1456.
19. A receptor subunit mRNAs in the rat brain II. Olfactory bulb and cerebellum. Journal of Neuroscience 12: 1063-1076.
20. A receptor subunit mRNAs in the rat brain III. Embryonic and postnatal development. Journal of Neuroscience 12: 4151-4172.
21. Lauven P. M., Schwilden H. and Stoeckel H. (1987) Threshold hypnotic concentration of methohexitone. European Journal of Clinical Pharmacology 33: 261-265.
22. A receptors in hippocampal neurons. Journal of Pharmacology and Experimental Therapeutics 264: 1097-1103.
23. A receptor selective for a behavioural alcohol antagonist. Nature 346: 648-651.
24. A receptor channels. Annual Reviews in Neuroscience 17: 569-602.
25. A receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification. Journal of Biological Chemistry 268: 5965-5973.
26. Nicoll R. A., Eccles J. C., Oshima T. and Rubia C. (1975) Prolongation of hippocampal inhibitory post-synaptic potentials by barbiturates. Nature 258: 625627.
27. A receptors. FASEB Journal 4: 1469-1480.
28. A receptors by general anesthetics. Society for Neuroscience Abstracts 26: 511-512.
29. Peoples R. W. and Weight F. F. (1994) Trichloroethanol potentiation of γ-aminobutyric acid-activated chloride current in mouse hippocampal neurons. British Journal of Pharmacology 113: 555-563.
30. A receptor subunit for benzodiazepine pharmacology. Nature 338: 582-585.
31. A receptor research. Synapse 21: 189-274.
32. A receptors: influence of receptor subunits. Journal of Pharmacology and Experimental Therapeutics 274: 353-360.
33. Sanna E., Garau F. and Harris R. A. (1995b) Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital. Molecular Pharmacology 47: 213-217.
34. Study R. E. and Barker J. L. (1981) Diazepam and (-)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of γ-aminobutyric acid responses in cultured central neurons. Proceedings of the National Academy of Sciences of the U.S.A. 78: 7180-7184.
35. Thompson S. A., Whiting P. J. and Wafford K. A. (1996) Alpha subunits influence the action of pentobarbital on recombinant GABA-A receptors. British Journal of Pharmacology 117: 521-527.
36. A receptors. In: The Handbook of Receptors and Channels: Ligand and Voltage-gated Ion Channels (North R. A., Ed.), pp. 265-290. CRC Press, Boca Raton, FL.
37. A receptors containing the α4 subunit. Molecular Pharmacology 50: 670-678.
38. Wakamori M., Ikemoto Y. and Akaike N. (1991) Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat. Journal of Neurophysiology 66: 2014-2021.
39. A receptor subunit mRNAs in rat lumbar spinal cord. Brain Research and Molecular Brain Research 10: 179-183.
40. A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. Journal of Neuroscience 12: 1040-1062.
41. A receptor CP current correlates with in vivo anesthetic potency. Journal of Pharmacology and Experimental Therapeutics 270: 987-991.