Local and downstream effects of excitotoxic lesions in the rat medial prefrontal cortex on in vivo 1H-MRS signals

Neuropsychopharmacology

Volumn 22, Issue 4, 2000, Pages 430-439

  Roffman, Joshua L ^a,b   Lipska, Barbara K ^a   Bertolino, Alessandro ^a   Van Gelderen, Peter ^c   Olson, Alan W ^c   Khaing, Zin Z ^a   Weinberger, Daniel R ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Glutamic acid decarboxylase 67; Ibotenic acid; Locomotor activity; N acetylaspartate; Prefrontal cortex; Striatum

Indexed keywords

AMPHETAMINE; GLUTAMATE DECARBOXYLASE; N ACETYLASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; LOCOMOTION; MALE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SCHIZOPHRENIA;

AMPHETAMINE; ANIMALS; ASPARTIC ACID; CORPUS STRIATUM; DENERVATION; DOPAMINE AGENTS; EFFERENT PATHWAYS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; IN SITU HYBRIDIZATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOTOR ACTIVITY; NEURONS; NEUROTOXINS; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0033984458     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00143-8     Document Type: Article

References (43)

1. Andreasen N.C., Flashman L., Flaum M., Arndt S., Swayze V.N., O'Leary D.S., Ehrhardt J.C., Yuh W.T. Regional brain abnormalities in schizophrenia measured with magnetic resonance imaging. JAMA. 272:1994;1763-1769.
2. Baca S.M., Lipska B.K., Egan M.F., Bachus S.E., Ferguson J.N., Hyde T.M. Effects of prefrontal cortical lesions on neuropeptide and dopamine receptor gene expression in the striatum-accumbens complex. Brain Res. 797:1998;55-64.
3. Bertolino A., Callicott J.H., Nawroz S., Mattay V.S., Duyn J.H., Tedeschi G., Frank J.A., Weinberger D.R. Reproducibility of proton magnetic resonance spectroscopic imaging in patients with schizophrenia. Neuropsychopharmacology. 18:1998;1-9.
4. Bertolino A., Knable M.B., Saunders R.C., Callicott J.H., Kolachana B., Mattay V.S., Bachevalier J., Frank J.A., Egan M.F., Weinberger D.R. The relationship between dorsolateral prefrontal N-acetylaspartate measures and striatal dopamine activity in schizophrenia. Biol Psychiatry. 45:1999;660-667.
5. Bertolino A., Nawroz S., Mattay V.S., Barnett A.S., Duyn J.H., Moonen C.T.W., Frank J.A., Tedeschi G., Weinberger D.R. Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging. Am J Psychiatry. 153:1996;1554-1563.
6. Callicott J.H., Ramsey N.F., Tallent K., Bertolino A., Knable M.B., Coppola R., Goldberg T., van Gelderen P., Mattay V.S., Frank J.A., Moonen C.T., Weinberger D.R. Functional magnetic resonance brain mapping in psychiatry. Methodological issues illustrated in a study of working memory in schizophrenia Neuropsychopharmacology. 18:1998;186-196.
7. Carter C.S., Perlstein W., Ganguli R., Brar J., Mintun M., Cohen J.D. Functional hypofrontality and working memory dysfunction in schizophrenia. Am J Psychiatry. 155:1998;1285-1287.
8. Cooper J.R., Bloom F.E., Roth R.H. The Biochemical Basis of Neuropharmacology. 6th ed:1991;Oxford University Press, New York.
9. Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia. A review and reconceptualization Am J Psychiatry. 148:1991;1474-1486.
10. 1-like receptors in the ventral tegmental area. Eur J Pharmacol. 336:1997;155-158.
11. Fletcher P.C., McKenna P.J., Frith C.D., Crasby P.M., Friston K.J., Dolan R.J. Brain activations in schizophrenia during a graded memory task studied with functional neuroimaging. Arch Gen Psychiatry. 55:1998;1001-1008.
12. Gerfen C.R., Wilson C.J. The basal ganglia. Swanson L.W., Björklund A., Hökfelt T. Handbook of Chemical Neuroanatomy. Vol 12. 1996;371-468 Part III. New York, Elsevier, Integrated Systems of the CNS.
13. Goldberg T.E., Gold J.M. Neurocognitive deficits in schizophrenia. Hirsch S.R., Weinberger D.R. Schizophrenia. 1995;146-162 Blackwell Science Ltd, Oxford.
14. Gorelova N., Yang C.R. The course of neural projection from the prefrontal cortex to the nucleus accumbens in the rat. Neuroscience. 76:1997;689-706.
15. Grace A.A. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity. A hypothesis for the etiology of schizophrenia Neuroscience. 41:1991;1-24.
16. 1H nuclear magnetic resonance spectroscopic imaging of neuronal loss in rat brain. Neuroscience. 69:1995;1095-1101.
17. Jaskiw G.E., Karoum F., Freed W.J., Phillips I., Kleinman J.E., Weinberger D.R. Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat. Brain Res. 534:1990;263-272.
18. Karreman M., Moghaddam B. The prefrontal cortex regulates the basal release of dopamine in the limbic striatum. An effect mediated by ventral tegmental area J Neurochem. 66:1996;589-598.
19. Laprade N., Soghomonian J.J. Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum. Mol Brain Res. 34:1995;65-74.
20. Lieberman J., Kane J., Alvir J. Provocative tests with psychostimulant drugs in schizophrenia. Psychopharmacology. 91:1987;415-433.
21. Manoach D.S., Press D.Z., Thangaraj V., Searl M.M., Goff D.C., Halpern E., Saper C.B., Warach S. Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biol Psychiatry. 45:1999;1128-1137.
22. Murase S., Grenhoff J., Chouvet G., Gonon F.G., Svensson T.H. Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons studied in vivo. Neurosci Lett. 157:1993;53-56.
23. Nasrallah H.A., Skinner T.E., Schmalbrock P., Robitaille P.M. Proton magnetic resonance spectroscopy of the hippocampal formation in schizophrenia. A pilot study Br J Psychiatry. 165:1994;481-485.
24. Pakkenberg B. Post-mortem study of chronic schizophrenic brains. Br J Psychiatry. 151:1987;744-752.
25. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates, Compact. 3rd ed:1986;Orlando, Academic Press, Sydney.
26. Peroutka S.J., Snyder S.H. Relationship between neuroleptic effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency. Am J Psychiatry. 137:1980;1518-1522.
27. 1H magnetic resonance spectroscopy study Magn Reson Med. 33:1995;595-600.
28. Saunders R.C., Kolachana B.S., Bachevalier J., Weinberger D.R. Neonatal lesions of the medial temporal lobe disrupt prefrontal cortical regulation of striatal dopamine. Nature. 393:1998;169-171.
29. Selemon L.D., Rajkowska G., Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area. 9(and occipital area 17. Arch Gen Psychiatry 52):1995;805-818.
30. Sesack S.R., Deutch A.Y., Roth R.H., Bunney B.S. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat. An anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin J Comp Neurol. 290:1989;213-242.
31. Sesack S.R., Pickel V.M. Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J Comp Neurol. 320:1992;145-160.
32. 67 expression in various regions of rat brain. J Neurosci Res. 52:1998;736-741.
33. Shim S.S., Bunney B.S., Shi W.-X. Effects of lesions in the medial prefrontal cortex on the activity of midbrain dopamine neurons. Neuropsychopharmacology. 15:1996;437-441.
34. 1H magnetic resonance spectroscopic imaging analysis of quinolinic acid-induced damage to the rat striatum. Magn Reson Med. 37:1997;24-33.
35. Taber M.T., Das S., Fibiger H.C. Cortical regulation of subcortical dopamine release. Mediation via the ventral tegmental area J Neurochem. 65:1995;1407-1410.
36. Taber M.T., Fibiger H.C. Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat. Modulation by metabotropic glutamate receptors J Neurosci. 5:1995;3896-3904.
37. Takagishi M., Chiba T. Efferent projections of the infralimbic (area 25) region of the medial prefrontal cortex in the rat. An anterograde tracer PHA-L study Brain Res. 566:1991;26-39.
38. Tsai G., Coyle J.T. N-acetylaspartate in neuropsychiatric disorders. Prog Neurobiol. 46:1995;531-540.
39. Tsai G., Passani L.A., Slusher B.S., Carter R., Kleinman J.E., Coyle J.T. Changes of excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry. 52:1995;829-836.
40. Urenjak J., Williams S.R., Gadian D.G., Noble M. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci. 13:1993;981-989.
41. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry. 44:1987;660-669.
42. Weinberger D.R., Berman K.F., Zec R.F. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry. 43:1986;114-125.
43. Yurgelun-Todd D.A., Renshaw P.F., Gruber S.A., Waternaux C.M., Cohen B.M. Proton magnetic resonance spectroscopy of the temporal lobes in schizophrenics and normal controls. Schizophr Res. 19:1996;55-59.