Excitotoxic lesions of the prefrontal cortex reduce dopamine D1-like receptors in the ventral tegmental area

European Journal of Pharmacology

Volumn 336, Issue 2-3, 1997, Pages 155-158

  Dewar, Karen M ^a   Rompré, Pierre Paul ^a,b   Stewart, Jane ^c   Warren, Richard A ^a  

^a CENTRE DE RECHERCHE FERNAND SEGUIN   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c and Applied Physiology   (Canada)

Author keywords

Dopamine D1 receptor; Medial prefrontal cortex; Substantia nigra; Ventral tegmental area

Indexed keywords

DOPAMINE 1 RECEPTOR; IBOTENIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN INJURY; CONTROLLED STUDY; DOSE RESPONSE; MALE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; VENTRAL TEGMENTUM;

ANIMALS; AUTORADIOGRAPHY; EXCITATORY AMINO ACID AGONISTS; FUNCTIONAL LATERALITY; IBOTENIC ACID; INJECTIONS, INTRAVENTRICULAR; MALE; PREFRONTAL CORTEX; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1; SUBSTANTIA NIGRA; VENTRAL TEGMENTAL AREA;

EID: 0030668413     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01256-9     Document Type: Article

References (11)

1. 2 receptor gene expression in the rat frontal cortex: Cellular localization in different classes of efferent neurons. Eur. J. Neurosci. 7:1995;1050.
2. 1 receptors modulate glutamate transmission in the ventral tegmental area. J. Neurosci. 15(7):1995;5379.
3. Kalivas P.W., Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Rev. 16:1991;223.
4. Karler R., Clader L.D., Chaudhry I.A., Turkanis S.A. Blockade of 'reverse tolerance' to cocaine and amphetamine by MK-801. Life Sci. 45(7):1989;599.
5. 1 receptor mRNA in projections from the forebrain to the ventral tegmental area. Synapse. 25(2):1997;205-214.
6. 3 receptor mRNAs in human and rat brain. Neurochem. Int. 20:1992;33S.
7. Paxinos G., Watson, C., 1986. The Rat Brain in Stereotaxic Coordinates. Academic, New York.
8. Sesack S.R., Pickel V.M. Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J. Comp. Neurol. 320:1992;145.
9. Sesack S.R., Deutch A.Y., Roth R.H., Bunney B.S. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin. J. Comp. Neurol. 290:1989;213.
10. 1 dopamine receptor activation is necessary for the induction of sensitization by amphetamine in the ventral tegmental area. J. Neurosci. 16(7):1996;2411.
11. Wolf M.E., Dahlin S.L., Hu X.T., Xue C.J., White F.J. Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-D-aspartate antagonists. Neuroscience. 69:1995;417.