24R,25-(OH)2D3 mediates its membrane receptor-dependent effects on protein kinase C and alkaline phosphatase via phospholipase A2 and cyclooxygenase-1 but not cyclooxygenase-2 in growth plate chondrocytes

Journal of Cellular Physiology

Volumn 182, Issue 3, 2000, Pages 390-401

  Schwartz, Z ^a,b   Sylvia, V L ^a   Del Toro, F ^a   Hardin, R R ^a   Dean, D D ^a   Boyan, B D ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

24,25 DIHYDROXYCOLECALCIFEROL; ALKALINE PHOSPHATASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INDOMETACIN; LIPOXYGENASE; MEPACRINE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHOSPHOLIPASE A2; RESVERATROL;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH PLATE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

24,25-DIHYDROXYVITAMIN D 3; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CHONDROCYTES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GROWTH PLATE; INDOMETHACIN; ISOENZYMES; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; MALE; MEMBRANE PROTEINS; NITROBENZENES; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEROID HYDROXYLASES; SULFONAMIDES; SULFUR RADIOISOTOPES; THYMIDINE; TRANSCRIPTION, GENETIC; TRITIUM; UMBELLIFERONES;

EID: 0033984090     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200003)182:3<390::AID-JCP10>3.0.CO;2-T     Document Type: Article

References (53)

1. Atkin I, Pita JC, Ornoy A, Agundez A, Castiglione G, Howell DS. 1985. Effects of vitamin D metabolites on healing of low phosphate, vitamin D-deficient induced rickets in rats. Bone 6:113-123.
2. Atkin I, Dean DD, Muniz OE, Agundez A, Castiglione G, Cohen G, Howell DS, Ornoy A. 1992. Enhancement of osteoinduction by vitamin D metabolites in rachitic host rats. J Bone Miner Res 7:863-875.
3. Bell RM, Hannun Y, Loomis C. 1986. Mixed micelle assay of protein kinase C. Methods Enzymol 124:353-359.
4. Bocos C, Gottlicher M, Gearing K, Banner C, Enmark E, Teboul M, Crickmore A, Gustafsson J. 1995. Fatty acid activation of peroxisome proliferator-activated receptor (PPAR). J Steroid Biochem Mol Biol 53:467-473.
5. 3 responsive alkaline phosphatase in osteoblast-like cells (ROS 17/2.8, MG 63, and MC 3T3) and growth cartilage cells in culture. J Biol Chem 264:11879-11886.
6. Boyan BD, Schwartz Z, Swain LD. 1992. In vitro studies on the regulation of endochondral ossification by vitamin D. Crit Rev Oral Biol Med 3:15-30.
7. 3. In: Feldman D, Glorieux FH, Pike JW, editors. Vitamin D. San Diego, CA: Academic Press. p 395-421.
8. 2 and arachidonic acid. In: Norman AW, Bouillon R, Thomasset M, editors. Vitamin D: chemistry, biology, and clinical applications of the steroid hormone. Riverside, CA: University of California at Riverside. p 353-360.
9. 3 on growth plate chondrocytes. J Cell Physiol 176:516-524.
10. 2 activation, platelet-activating factor generation and prostacyclin release in spontaneously beating rat cardiomyocytes. Biochem J 290:477-482.
11. 3 alters chondrocyte proliferation and differentiation by regulating EP1 receptor signaling. Trans Orthop Res Soc 24:719.
12. 3-mediated effects on resting zone chondrocytes. J Cell Physiol (in press).
13. DeWitt DL, Smith WL. 1988. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA 85:1412-1416.
14. Dziak RM. 1985. Prostaglandins as mediators of bone cell metabolism. In: Rubin RP, Weiss GB, Putney JW, editors. Calcium in biological systems. New York: Plenum Publishing. p 533-539.
15. Fletcher JR. 1993. Eicosanoids. Critical agents in the physiological process and cellular injury. Arch Surg 128:1192-1196.
16. Futaki N, Takahashi S, Yokoyama M, Arai I, Higuchi S, Otomo S. 1994. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins 47:55-59.
17. Garabedian M, DuBois MB, Corvol MT, Pezant E, Balsan S. 1978. Vitamin D and cartilage. I. In vitro metabolism of 25-hydroxycholecalciferol by cartilage. Endocrinology 102:1262-1268.
18. Giaume C, Randriamampita C, Trautmann A. 1997. Arachidonic acid closes gap junction channels in rat lacrimal glands. Eur J Physiol 413:273-279.
19. Habermann E. 1972. Bee and wasp venoms. Science 177:314-322.
20. Hale LV, Kemick ML, Wuthier RE. 1986. Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture. J Bone Miner Res 1:489-495.
21. 3 regulates protein kinase C through two distinct phospholipid-dependent mechanisms. J Cell Physiol 169:509-521.
22. Hope WC, Welton AF, Fiedler-Nagy C, Batula-Bernardo C, Coffey JW. 1983. In vitro inhibition of the biosynthesis of slow reacting substance of anaphylaxis (SRS-A) and lipoxygenase activity by quercetin. Biochem Pharmacol 32:367-371.
23. Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275:218-220.
24. Kaplan MD, Olschowska JA, O'Banion MK. 1997. Cyclooxygenase-1 behaves as a delayed response gene in PC12 cells differentiated by nerve growth factor. J Biol Chem 272:18534-18537.
25. 3: evidence for a nonnuclear membrane receptor in the chick tibial fracture-healing callus. Bone 23:141-146.
26. 3 on calcium ion fluxes in costochondral chondrocyte cultures. Calcif Tissue Int 47: 230-236.
27. Lopez-Ruiz MP, Choi MS, Rose MP, West AP, Cooke BA. 1992. Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C. Endocrinology 130: 1122-1130.
28. Neichi T, Koshihara Y, Murota S. 1983. Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis. Biochim Biophys Acta 753:130-132.
29. O'Keefe RJ, Puzas JE, Brand JS, Rosier RN. 1988. Effects of transforming growth factor-beta on matrix synthesis by chick growth plate chondrocytes. Endocrinology 122:2953-2961.
30. Otto JC, Smith WL. 1995. Prostaglandin endoperoxide synthases-1 and -2. J Lipid Mediat Cell Sig 12:139-156.
31. 3 1-and 24-hydroxylase activity in cultured growth plate chondrocytes in a maturation-dependent manner. Calcif Tissue Int 64:50-56.
32. 3. J Bone Miner Res 14:856-867.
33. Raisz LG, Pilbeam CC, Fall PM. 1993. Prostaglandins: mechanisms of action and regulation of production in bone. Osteoporosis Int 3:136-140.
34. 2 activity of growth zone and resting zone cartilage cells in vitro. Endocrinology 122:2191-2198.
35. 2 specific activities. Endocrinology 123:2878-2884.
36. Schwartz Z, Schlader DL, Ramirez V, Kennedy MB, Boyan BD. 1989. Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro. J Bone Miner Res 4:199-207.
37. 3 in growth zone and resting zone chondrocyte cultures. Biochim Biophys Acta 1027:278-286.
38. 3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors. Endocrinology 130: 2495-2504.
39. 2 production by vitamin D metabolites in growth zone and resting zone chondrocyte cultures is dependent on cell maturation. Bone 13:395-401.
40. 3-responsive phenotype characteristic of growth zone chondrocytes. Endocrinology 136:402-411.
41. 2 on costochondral chondrocyte differentiation is mediated by cAMP and protein kinase C. Endocrinology 139:1825-1834.
42. 3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. Endocrinology (in press).
43. 3 in growth plate cartilage of rats. Endocrine 5:147-155.
44. 3. J Biol Chem 270:6639-6643.
45. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150:76-85.
46. St-Arnaud R, Glorieux FH. 1998. Editorial: 24,25-dihydroxyvitamin D - active metabolite or inactive catabolite. Endocrinology 139:3371-3374.
47. 2. Biochim Biophys Acta 1136:45-51.
48. 3 is dependent on cell maturation. Bone 14:609-617.
49. 3 metabolites in chondrocyte cultures. J Cell Physiol 157:271-278.
50. 3. J Cell Physiol 167:380-393.
51. 3 regulation of matrix vesicle protein kinase C occurs both during biosynthesis and in the extracellular matrix. Calcif Tissue Int 61:313-321.
52. Vane JR. 1971. Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs. Nature 231:232-235.
53. Vane JR, Bakhle YS, Botting RM. 1998. Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 38:97-120.