24,25-(OH)2D3 regulates protein kinase C through two distinct phospholipid-dependent mechanisms

Journal of Cellular Physiology

Volumn 169, Issue 3, 1996, Pages 509-521

  Helm, S ^a,b   Sylvia, V L ^a   Harmon, T ^a   Dean, D D ^a   Boyan, B D ^a   Schwartz, Z ^a,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b WILFORD HALL MEDICAL CENTER   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 24,25 DIHYDROXYCOLECALCIFEROL; 6 [2 [4 [(4 FLUOROPHENYL)PHENYLMETHYLENE] 1 PIPERIDYL]ETHYL] 7 METHYL 5H THIAZOLO[3,2 A]PYRIMIDIN 5 ONE; CHELERYTHRINE; CHOLERA TOXIN; DIACYLGLYCEROL; DIOCTANOIN; ENZYME INHIBITOR; GENISTEIN; INDOMETACIN; MEPACRINE; PERTUSSIS TOXIN; PROSTAGLANDIN E2; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

24,25-DIHYDROXYVITAMIN D 3; ALKALOIDS; BENZOPHENANTHRIDINES; CYCLOOXYGENASE INHIBITORS; DIACYLGLYCEROL KINASE; DIGLYCERIDES; ENZYME INHIBITORS; GTP-BINDING PROTEINS; PHENANTHRIDINES; PHOSPHOLIPASE C; PHOSPHOLIPASES A; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

ANIMALIA; CANIS FAMILIARIS;

EID: 0030453094     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199612)169:3<509::AID-JCP11>3.0.CO;2-0     Document Type: Article

References (37)

1. Anderson, H.C. (1969) Vesicles associated with calcification in the matrix of epiphyseal cartilage. J. Cell. Biol., 41:59-72.
2. Azarani, A., Goltzman, D., and Orlowski, J. (1995) Parathyroid hormone and parathyroid hormone-related peptide inhibit the apical Na+/H+ exchanger NHE-3 isoform in renal cells (OK) via a dual signaling cascade involving protein kinase A and C. J. Biol. Chem., 270:20004-20010.
3. Barg, J., Belcheva, M.M., and Coscia, C.J. (1992) Evidence for the implication of phosphoinositol signal transduction in mu-opioid inhibition of DNA synthesis. J. Neurochem., 59:1145-1152.
4. Bell, R.M., Hannun, Y., and Loomis, C. (1986) Mixed micelle assay of protein kinase C. Methods Enzymol., 124:353-359.
5. Billah, M.M., and Anthes, J.C. (1990) The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem. J., 269:281-291.
6. Bleasdale, J., Bundy, G.L., Bunting, S., Fitzpatrick, F.A., Huff, R.M., Sun, F.F., and Pike, J.E. (1989) Inhibition of phospholipase C-dependent processes by U73,122. Adv. Prostaglandin Thromboxane Leukot. Res., 19:590-593.
7. Boskey, A.L. (1981) Current concepts of the physiology and biochemistry of calcification. Clin. Orthop. Rel. Res., 157:225-255.
8. Boyan, B.D., Schwartz, Z., Swain, L.D., Carnes, D.L. Jr., and Zislis, T. (1988a) Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro. Bone, 9:185-194.
9. Boyan, B.D., Schwartz, Z., Carnes, D.L., and Ramirez, V. (1988b) The effects of vitamin D metabolites on the plasma and matrix vesicle membranes of growth and resting cartilage cells in vitro. Endocrinology, 122:2851-60.
10. Boyan B.D., Schwartz, Z, Swain, L.D. (1992) In vitro studies on the regulation of endochondral ossification by vitamin D. Crit. Rev. Oral Biol. Med., 3:15-30.
11. 2 activation, platelet-activating factor generation and prostacyclin release in spontaneously beating rat cardiomyocytes. Biochem. J., 290:477-482.
12. 3 signal transduction in chick myoblasts involves phosphatidylcholine hydrolysis. J. Biol. Chem., 269:8675-8679.
13. 2 regulation of chondrocyte proliferation and differentiation. J. Dental Res., 72:299.
14. Godfrey, P.P. (1989) Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol. Biochem. J., 258:621-624.
15. Herbert, J.M., Augereau, J.M., Gleye, J., and Maffrand, J.P. (1990) Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun., 172:993-999.
16. 2 activation in intact human platelets. FEBS Lett., 381:244-248.
17. 2 alpha activates phospholipase D independently from activation of protein kinase C in osteoblast-like cells. J. Cell. Biochem., 55:373-379.
18. 3 on calcium ion fluxes in costochondral chondrocyte cultures. Calcif. Tissue Int., 47:230-236.
19. Lapetina, E.G., Reep, B., Ganong, B.R., and Bell, R.M. (1985) Exogenous sn-1,2-diacylglycerol containing fatty acids function as bioregulators of protein kinase C in human platelets. J. Biol. Chem., 260:1358-1361.
20. 2 inhibitors. J. Cell. Biochem., 40:371-386.
21. 2 in Chinese hamster ovary cells. Eur. J. Biochem., 230:164-169.
22. Newton, A.C. (1995) Protein Kinase C: Structure, function and regulation. J. Biol. Chem., 270:28495-28498.
23. Nishibe, S., Wahl, M.I., Hernandez-Sotomayor, S.M., Tonks, N.K., Rhee, S.G., and Carpenter, G. (1990) Increase of the catalytic activity of phospholipase C-gamma by tyrosine phosphorylation. Science, 250:1253-1256.
24. Nishizuka, Y. (1995) Protein Kinase C and lipid signaling for sustained cellular responses. FASEB J., 9:484-496.
25. Perez, D.M., DeYoung, M.B., and Graham, R.M. (1993) Coupling of expressed alpha 1B- and alpha 1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific. Molec. Pharmacol., 44:784-795.
26. 2 activity on growth zone and resting zone cartilage cells in vitro. Endocrinology, 122:2191-2198.
27. 2 specific activities. Endocrinology, 123:2878-2884.
28. Schwartz, Z., Schlader, D.L., Ramirez, V., Kennedy, M.B. and Boyan, B.D. (1989) Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro. J. Bone Min. Res., 4:199-207.
29. 3 in growth zone and resting zone chondrocyte cultures. Biochim. Biophys. Acta, 1027:278-286.
30. 2 production by vitamin D is dependent on cell maturation. Bone, 13:395-401.
31. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., and Klenk, D.C. (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem., 150:76-85.
32. 2. Biochemistry, 32:5935-5940.
33. 2. Biochim. Biophys. Acta, 1136:45-51.
34. 3 is dependent on cell maturation. Bone, 14:609-617.
35. 3 metabolites in chondrocyte cultures. J. Cell. Physiol., 157:271-278.
36. Sylvia, V.L., Mackey, S., Schwartz, Z., Schuman, L., Gomez, R. and Boyan, B.D. (1994) Regulation of protein kinase C by transforming growth factor 1 in rat costochondral chondrocyte cultures. J. Bone Min. Res., 9:1477-1487.
37. 3. J. Cell. Physiol., 167:380-393.