Metalloprotease activity in a small heat shock protein of the human malaria parasite Plasmodium vivax

Infection and Immunity

Volumn 68, Issue 3, 2000, Pages 1202-1206

  Fakruddin, J Mohamed ^a   Biswas, Sukla ^b   Sharma, Yagya D ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; METALLOPROTEINASE; PROTOZOAL PROTEIN;

ARTICLE; ENZYME ACTIVITY; NONHUMAN; PLASMODIUM VIVAX; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ZYMOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; HEAT-SHOCK PROTEINS; HUMANS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PLASMODIUM VIVAX; PROTEASE INHIBITORS;

EID: 0033982190     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.3.1202-1206.2000     Document Type: Article

References (42)

1. Barale, J. C., T. Blisnick, H. Fujioka, P. M. Alzari, M. Aikawa, C. Braun-Breton, and G. Langsley. 1999. Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase. Proc. Natl. Acad. Sci. USA 96:6445-6450.
2. Blackman, M. J., J. A. Chappel, S. Shai, and A. A. Holder. 1993. A conserved parasite serine protease processes the Plasmodium falciparum Merozoite Surface Protein-1. Mol. Biochem. Parasitol. 62:103-114.
3. Blackman, M. J., H. Fujioka, W. H. L. Stafford, M. Sajid, B. Clough, S. L. Fleck, M. Aikawa, M. Grainger, and F. Hackett. 1998. A subtilisin-like protein in secretory organelles of Plasmodium falciparum merozoites. J. Biol. Chem. 273:23398-23409.
4. Bonnefoy, S., G. Attal, G. Langsley, F. Tekaia, and O. Mercereau-Puijalon. 1994. Molecular characterization of the heat shock protein 90 gene of the human malaria parasite Plasmodium falciparum. Mol. Biochem. Parasitol. 67:157-170.
5. Braun-Breton, C., T. Blisnick, H. Jouin, J. C. Barale, T. Rabilloud, G. Langsley, and L. H. Pereira Da Silva. 1988. Activation of a Plasmodium falciparum protease correlated with merozoite maturation and erythrocyte invasion. Proc. Natl. Acad. Sci. USA 89:9647-9651.
6. Braun-Breton, C., and L. H. Pereira da Silva. 1993. Malarial proteases and red blood cell invasion. Parasitol. Today 9:92-96.
7. Bukau, B., and A. Horwich. 1998. The HSP70 and HSP60 chaperone machines. Cell 92:351-366.
8. Chaudhuri, G., M. Chaudhuri, A. Pan, and K. P. Chang. 1989. Surface acid proteinase (gp63) of Leishmania maxicana. A metalloenzyme capable of protecting liposome encapsulated proteins from phagolysosomal degradation by macrophages. J. Biol. Chem. 264:7483-7489.
9. Dreyfus, L. A., and B. H. Iglewski. 1986. Purification and characterization of an extra cellular protease of Legionella pneumophila. Infect. Immun. 51:736-743.
10. Dulzewski, A. R., K. Rangachari, R. J. M. Wilson, and W. B. C. Gratzer. 1986. Plasmodium falciparum: protease inhibitors and inhibition of erythrocyte invasion. Exp. Parasitol. 62:416-422.
11. Dutta, G. P., and H. S. Banyal. 1981. In vitro susceptibility of erythrocytes of Presbytisentellus (Indian Langur) to Plasmodium knowlesi and blocking of merozoite invasion process by certain protease inhibitors. Indian J. Exp. Biol. 19:9-11.
12. Eakin, A. E., A. A. Mills, G. Harth, J. H. McKerrow, and C. S. Craik. 1992. The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi. J. Biol. Chem. 267:7411-7420.
13. Fakruddin, J. M., S. Biswas, and Y. D. Sharma. 1997. Identification of Plasmodium vivax heat shock protein which contains a metalloprotease sequence motif. Mol. Biochem. Parasitol. 90:387-390.
14. Florent, I., Z. Derhy, M. Allary, M. Monsigny, R. Mayer, and J. Schrevel. 1998. A Plasmodium falciparum aminopeptidase gene belonging to the M1 family of zinc-metallopeptidases is expressed in erythrocytic stages. Mol. Biochem. Parasitol. 97:149-160.
15. Francis, S. E., I. Y. Gluzman, A. Oksman, A. Knickerbocker, R. Muller, M. I. Bryant, D. R. Sherman, D. G. Russel, and D. E. Goldberg. 1994. Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase. EMBO J. 13:306-317.
16. Fujimura-Kamada, K., F. J. Nouvet, and S. Michaelis. 1997. A novel membrane-associated metalloprotease, Ste 24P, is required for the first step of NH2-terminal processing of the yeast alpha factor precursor. J. Cell Biol. 136:271-285.
17. Gantt, S. M., J. M. Myung, M. R. Briones, W. D. Li, E. J. Corey, S. Omura, V. Nussenzweig, and P. Sinnis. 1998. Proteosome inhibitors block development of Plasmodium spp. Antimicrob. Agents Chemother. 42:2731-2738.
18. Gluzman, I. Y., S. E. Francis, A. Oksman, C. E. Smith, K. L. Duffin, and D. E. Goldberg. 1994. Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway. J. Clin. Investig. 93:1602-1608.
19. Gottesman, M. M., and F. Cabral. 1981. Purification and characterization of a transformation-dependent protein secreted by cultured murine fibroblasts. Biochemistry 20:1659-1665.
20. Gottesman, S. 1996. Proteases and their targets in Escherichia coli. Annu. Rev. Genet. 30:465-506.
21. Hase, C. C., and R. A. Finkelstein. 1991. Cloning and nucleotide sequence of the Vibrio cholerae hemagglutinin/protease (HA/protease) gene and construction of an HA/protease-negative strain. J. Bacteriol. 173:3311-3317.
22. Heussen, C., and E. B. Dowdle. 1980. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal. Biochem. 102:196-202.
23. Holloway, S. P., W. Min, and J. S. Inselburg. 1994. Isolation and characterization of a chaperonin-60 gene of the human malaria parasite Plasmodium falciparum. Mol. Biochem. Parasitol. 64:25-32.
24. Jongeneel, C. V., J. Bouvier, and A. Bairoch. 1989. A unique signature identifies a family of zinc-dependent metallopeptidases. FEBS Lett. 242:211-214.
25. Kumar, N., C. A. Syin, R. Carter, I. Quakyi, and L. H. Miller. 1988. Plasmodium falciparum gene encoding a protein similar to the 78-kDa rat glucose-regulated stress protein. Proc. Natl. Acad. Sci. USA 85:6277-6281.
26. Lindquist, S., and E. Craig. 1988. The heat-shock proteins. Annu. Rev. Genet. 22:631-677.
27. Makinen, P. L., D. B. Clewell, F. An, and K. K. Makinen. 1989. Purification and substrate specificity of a strongly hydrophobic extracellular metalloendopeptidase ("gelatinase") from Streptococcus faecalis (strain OGI-10). J. Biol. Chem. 264:3325-3334.
28. Morihara, K. 1995. Pseudolysin and other pathogen endopeptidases of thermolysin family. Methods Enzymol. 248:242-253.
29. Nankya-Kitaka, M. F., G. P. Curley, C. S. Gavigan, A. Bell, and J. P. Dalton. 1998. Plasmodium chabaudi chabaudi and P. falciparum: inhibition of aminopeptidase and parasite growth by bestatin and nitrobestatin. Parasitol. Res. 84:552-558.
30. Olliaro, P. L., M. Gottlieb, and D. F. Wirth. 1996. Plasmodium falciparum proteinases: targeted drug development. Parasitol. Today 12:413.
31. Rawlings, N. D., and A. J. Barrett. 1995. Evolutionary families of metallopeptidases. Methods Enzymol. 248:183-228.
32. Ray, P., M. A. Ansari, and Y. D. Sharma. 1994. Plasmodium vivax immune responses in a cross-section of the population in the Delhi area of India. Am. J. Trop. Med. Hyg. 51:436-443.
33. Rosenthal, P. J., J. H. McKarrow, M. Aikawa, H. Nagasawa, and J. H. Leech. 1988. A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum. J. Clin. Investig. 82:1560-1566.
34. Rosenthal, P. J., and R. G. Nelson. 1992. Isolation and characterization of a cysteine protease gene of Plasmodium falciparum. Mol. Biochem. Parasitol. 51:143-152.
35. Salas, F., J. Fichmann, G. K. Lee, M. D. Scott, and P. J. Rosenthal. 1995. Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase. Infect. Immun. 63:2120-2125.
36. Sharma, Y. D., V. P. Sharma, P. Ray, S. Laal, S. D. Sawant, and S. Verma. 1991. Isolation and serological characterization of a Plasmodium vivax recombinant antigen. Infect. Immun. 59:1922-1926.
37. Spiess, C., A. Beil, and M. Ehrmann. 1999. A temperature-dependent switch from chaperone to protease in a widely conserved heat-shock protein. Cell 97:339-347.
38. Tardieux, I., I. Baines, M. Mossakowska, and G. E. Ward. 1998. Actin-binding proteins of invasive malaria parasites and the regulation of actin polymerization by a complex of 32/34-kDa proteins associated with heat-shock protein 70kDa. Mol. Biochem. Parasitol. 93:295-308.
39. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
40. Walsh, J. A. 1989. Disease problem in the Third World. Ann. N.Y. Acad. Sci. 569:1-16.
41. Watanabe, J. 1997. Cloning and characterization of heat-shock protein Dnaj homologues from Plasmodium falciparum and comparison with ring infected erythrocyte surface antigen. Mol. Biochem. Parasitol. 88:253-258.
42. Yang, Y. F., P. Tan-ariya, Y. D. Sharma, and A. Kilejian. 1987. The primary structure of a Plasmodium falciparum polypeptide related to heat shock proteins. Mol. Biochem. Parasitol. 26:61-67.