Detection of loss of heterozygosity in the p53 tumor-suppressor gene with PCR in the urine of patients with bladder cancer

Journal of Urology

Volumn 163, Issue 3, 2000, Pages 1039-1042

  Friedrich, Martin G ^a,b   Erbersdobler, Andreas ^a   Schwaibold, Hartwig ^a   Conrad, Stefan ^a   Huland, Edith ^a   Huland, Hartwig ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Bladder cancer; LOH; p53; Urinary sediment

Indexed keywords

AGAR GEL ELECTROPHORESIS; ARTICLE; BLADDER BIOPSY; BLADDER CANCER; BLADDER MUCOSA; CANCER SCREENING; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; GENE AMPLIFICATION; HETEROZYGOSITY; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRANSITIONAL CELL CARCINOMA; TUMOR DIAGNOSIS; TUMOR SUPPRESSOR GENE; VARIABLE NUMBER OF TANDEM REPEAT;

EID: 0033980871     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)67878-0     Document Type: Article

References (26)

1. Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C. C.: p53 mutations in human cancers. Science, 253: 49, 1991
2. Caron de Fromentel, C. and Soussi, T.: TP 53 tumor suppressor gene: A model for investigating human mutagenesis. Genes, Chromosomes and Cancer, 4: 1, 1992
3. Miller, C. W., Simon, K., Aslo, A., Kok, K., Yokota, J., Buys, C. H. C. M., Terada, M. and Koeffler, H. P.: p53 in human lung tumors. Cancer Res, 52: 1695, 1992
4. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F. S., Weston, A., Modali, R., Harris, C. C. and Vogelstein, B.: Mutations of the p53 gene occur in diverse human tumour types. Nature, 342: 705, 1989
5. Horio, Y., Takahashi, T., Kuroishi, T., Hibi, K., Suyama, M., Niimi, T., Shimokata, K., Yamakawa, K., Nakamura, Y., Ueda, R. and Takahashi, T.: Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer. Cancer Res, 53: 1, 1993
6. Andersen, T. I., Holm, R., Nesland, J. M., Heimdahl, K. R., Ottestad, L. and Børresen, A-L.: Prognostic significance of TP53 alterations in breast cancer. Br J Cancer, 68: 540, 1993
7. Hamelin, R., Laurent-Puig, P., Olschwang, S., Jego, N., Asselein, B., Remvikos, Y., Girodet, J., Salmon, R. J. and Thomas, G.: Association of p53 mutations with short survival in colorectal cancer. Gastroenterology, 106: 42, 1994
8. Kakeji, Y., Korenaga, D., Tsujitani, S., Baba, H., Anai, H., Maehara, Y. and Sugimachi, K., Gastric cancer with p53 over-expression has a high potential for metastasizing to lymph nodes. Br J Cancer, 67: 589, 1993
9. Soini, Y., Turpeenniemi-Hujanen, T., Kamel, D., Autio-Harmainen, H., Risteli, J., Risteli, L., Nuorva, K., Nuorva, K., Pääkkö, P. and Vähäkangas, K.: p53 immunohistochemistry in transitional cell carcinoma and dysplasia of the urinary bladder correlates with disease progression. Br J Cancer, 68: 1029, 1993
10. Jeffreys, A. J.: DNA sequence variants in the Gγ-,. Aα-, δ- and β-globin genes of man. Cell, 18: 1, 1979
11. Ganly, P. S., Jarad, N., Rudd, R. M. and Rabbits, P. H.: PCR-based analysis allows genotyping of the short arm of chromosome 3 in small biopsies from patients with lung cancer. Genomics, 12: 221, 1992
12. Meltzer, S. J., Yin, J., Huang, Y., McDaniel, T. K., Newkirk, C., Iseri, O., Vogelstein, B. and Resau, J. H.: Reduction of homozygosity involving p53 in esophageal cancer demonstrated by polymerase chain reaction. Proc Natl Acad Sci USA, 88: 4976, 1991
13. Sugano, K., Tsutsui, M., Nakashima, Y., Yamaguchi, K., Ohkura, H., Kakizoe, T. and Sekiya, T.: Diagnosis of bladder cancer by analysis of the allelic loss of the p53 gene in urine samples using blunt-end single-strand conformation polymorphism. Int J Cancer, 74: 403, 1997
14. Steiner, G., Schoenberg, M. P., Linn, J., Mio, L. and Sidransky, D.: Detection of bladder cancer by microsatellite analysis of urine. Nature Medicine, 3: 621, 1997
15. Mao, L., Schoenberg, M. P., Scicchitano, M., Erozna, Y. S., Merlo, A., Schwab, D. and Sidransky, D.: Molecular detection of primary bladder cancer by microsatellite analysis. Science, 271: 659, 1996
16. Ridenpää, M., Antilla, S. and Husgafvel-Pursianen, K.: Detection of loss of heterozygosity in the p53 tumor suppressor gene using a PCR-based assay. Path Res Pract, 191: 399, 1995
17. Hahn, M., Serth, J., Fislage, R., Wolfes, H., Allhof, R., Jonas, U. and Pingoud, A.: Polymerase chain reaction detection of a highly polymorphic VNTR segment in intron 1 of the human p53 gene. Clin Chem, 39: 549, 1993
18. th edition). Wiley and Sons: New York, 1997
19. Rolfs, A., Schuller, I., Finckh, U. and Weber-Rolfs, I.: PCR: Clinical Diagnostics and Research. Springer Verlag: Berlin, 1992
20. Harris, C. C. and Hollstein, M.: Clinical implications of the p53 tumor suppressor gene. New Engl J Med, 329: 1318, 1993
21. Tsutsumi, M., Sugano, K., Yamaguchi, K. and Akaza, H.: Correlation of allelic loss of the p53 gene and tumor grade, stage and malignant progression in bladder cancer. Int J Urol, 4: 74, 1997
22. Kuczyk, M. A., Serth, J., Hervatin, C., Arndt, H., Derendorf, L., Thon, W. F. and Jonas, U.: Detection of p53 tumor-suppressorgene protein in bladder tumors and prostate cancer: possible clinical implications. World J Urol, 12: 345, 1994
23. Kuczyk, M. A., Serth, J., Bokemeyer, C., Jonassen, J., Arndt, H., Paeslak, U., Werner, M., Tan, H. T. and Jonas, U., Detection of p53 gene alteration in renal cell cancer by micropreparation techniques of tumor specimens. Int J Cancer, 64: 399, 1995
24. Linn, J. F., Lango, M., Halachmi, S., Schoenberg, M. P. and Sidransky, D.: Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients. Int J Cancer, 74: 625, 1997
25. Schneider, A., Borgnat, S., Regine, O., Saussine, C., Gaub, M. P., Oudet, P. and Jacqmin, D.: Allelotypes in urine sediment for the diagnosis of transitional cell carcinomas. J Urol, 159: 942A, 1998
26. Erbersdobler, A., Friedrich, M. G., Schwaibold, H., Henke, R-P. and Huland, H.: Allelic imbalance at chromosome 9p, 13q and 17p in non-muscle-invasive transitional-cell-carcinoma of the urinary bladder. Oncol Res, 10: 415, 1998