Diagnosis of bladder cancer by analysis of the allelic loss of the p53 gene in urine samples using blunt-end single-strand conformation polymorphism

International Journal of Cancer

Volumn 74, Issue 4, 1997, Pages 403-406

  Sugano, Kokichi ^a   Tsutsumi, Masakazu ^a   Nakashima, Yuki ^a   Yamaguchi, Kensei ^a   Ohkura, Hisanao ^a   Kakizoe, Tadao ^a   Sekiya, Takao ^b  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; PROTEIN P53;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST; FEMALE; GENETIC MARKER; HETEROZYGOSITY LOSS; HUMAN; MALE; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; URINALYSIS;

ALLELES; CHROMOSOME DELETION; DNA; DNA PRIMERS; DNA, NEOPLASM; EXONS; GENES, P53; HETEROZYGOTE DETECTION; HUMANS; INTRONS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; URINARY BLADDER NEOPLASMS;

EID: 0030799868     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970822)74:4<403::AID-IJC7>3.0.CO;2-Z     Document Type: Article

References (19)

1. CAIRNS, P., SHAW, M.E. and KNOWLES, M.A., Initiation of bladder cancer may involve deletion of a tumour-suppressor gene on chromosome 9. Oncogene, 8, 1083-1085 (1993).
2. CLARK, J.M., Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases. Nucleic Acids Res., 16, 9677-9686 (1988).
3. CORDON-CARDO, C., DALBAGNI, G., SAEZ, G.T., OLIVA, M.R., ZHANG, Z.-F., ROSAI, J., REUTHR, V.E. and PELLICER, A., A., p53 mutations in human bladder cancer: genotypic vs. phenotypic patterns. Int. J. Cancer, 56, 347-353 (1994).
4. DALBAGNI, G., PRESTI, J., REUTER, V., FAIR, W.R. and CORDON-CARDO, C., Genetic alterations in bladder cancer. Lancer, 342, 469-471 (1993).
5. ESRIG, D., ELMAJIAN, D., GROSHEN, S., FREEMAN, J.A., STEIN, J.P., CHEN, S.-C., NICHOLS, P.W., SKINNER, D.G., JONES, P.A. and COTE, R.J., Accumulation of nuclear p53 and tumor progression in bladder cancer. New Engl. J. Med., 331, 1259-1264 (1994).
6. GANLY, P.S., JARAD, N., RUDD, R.M. and RABBITTS, P.H., PCR-based analysis allows genotyping of the short arm of chromosome 3 in small biopsies from patients with lung cancer. Genomics, 12, 221-228 (1992).
7. HAHN, S.A., SEYMOUR, A.B., HOQUE, A.T.M.S., SCHUTTE, M., DA COSTA, L.T., REDSTON, M.S., CALDAS, C., WEINSTEIN, C.L., FISHER, A., YEO, C.J., HRUBAN, R.H. and KERN, S.E., Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res., 55, 74670-4675 (1995).
8. γ-, δ- and β-globin genes of man. Cell, 18, 1-10 (1979).
9. KNOWLES, M.A., ELDER, P.A., WILLIAMSON, M., CAIRNS, J.P., SHAW, M.E. and LAW, M.G., Allelotype of human bladder cancer. Cancer Res., 54, 531-538 (1994).
10. LEVI, S., URBANO-ISPIZUA, S., GILL, R., THOMAS, D.M., GILBERTSON, J., FOSTER, C. and MARSHALL, C.J., Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique. Cancer Res., 51, 3497-3502 (1991).
11. MAO, L., SCHOENBERG, M.P., SCICCHITANO, M., EROZAN, Y.S., MERLO, A., SCHWAB, D. and SIDRANSKY, D., Molecular detection of primary bladder cancer by microsatellite analysis. Science, 271, 659-662 (1996).
12. MELTZER, S.J., YIN, J., HUANG, Y., MCDANIEL, T.K., NEWKIRK, C., ISERI, O., VOGELSTEIN, B. and RESAU, J.H., Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction. Proc. nat. Acad. Sci. (Wash.), 88, 4976-4980 (1991).
13. MIESFELD, R., KRYSTAL, M. and AMHEIM, N., A member of a new repeated sequence family which is conserved throughout eucaryotic evolution is found between the human delta and beta globin genes. Nucleic Acids Res., 9, 5931-5947 (1981).
14. OLUMI, A.F., TSAI, Y.C., NICHOLS, P.W., SKINNER, D.G., CAIN, D.R., BENDER, L.I. and JONES, P.A., Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder. Cancer Res., 50, 7081-7083 (1990).
15. SIDRANSKY, D., ESCHENBACH, A.V., TSAI, Y.C., JONES, P., SUMMERHAYES, I., MARSHALL, F., PAUL, M., GREEN, P., HAMILTON, S.R., FROST, P. and VOGELSTEIN, B., Identification of p53 gene mutations in bladder cancers and urine samples. Science, 252, 706-709 (1991).
16. SPRUCK III, C.H. and 16 OTHERS, Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res., 54, 784-788 (1994).
17. SUGANO, K., KYOGOKU, A., FUKAYAMA, N., OHKURA, H., SHIMOSATO, Y., SEKIYA, T. and HAYASHI, K., Rapid and simple detection of c-Ki-ras2 gene codon 12 mutations by nonradioisotopic single-strand conformation polymorphism analysis. Lab. Invest., 68, 361-3661 (1993).
18. SUGANO, K., NAKASHIMA, Y., YAMAGUCHI, K., FUKAYAMA, N., MAEKAWA, M., OHKURA, H., KAKIZOE, T. and SEKIYA, T., Sensitive detection of loss of heterozygosity in the TP53 gene in pancreatic adenocarcinoma by fluorescence-based single-strand conformation polymorphism analysis using blunt-end DNA fragment. Genes Chromosomes Cancer, 15, 157-164 (1996).
19. YAMAGUCHI, K., SUGANO, K., KYOGOKU, A., NAKASHIMA, Y., SAOTOME, K., YOKOYAMA, T., YOKOTA, T., and OHKURA, H., PCR-based approaches for detection of allelic loss in the p53 tumor suppressor gene in colon neoplasms. Amer. J. Gastroenterol., 92, 307-312 (1997).