Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo

Journal of Cerebral Blood Flow and Metabolism

Volumn 17, Issue 2, 1997, Pages 153-160

  Bhardwaj, Anish ^a,b   Northington, Frances J ^a   Martin, Lee J ^a   Hanley, Daniel F ^a   Traystman, Richard J ^a   Koehler, Raymond C ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Metabotropic glutamate receptors; Microdialysis; Nitric oxide; Rat, Hippocampus

Indexed keywords

METABOTROPIC RECEPTOR; NITRIC OXIDE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN METABOLISM; BRAIN PERFUSION; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0031045483     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199702000-00004     Document Type: Article

References (46)

1. 2+ signal transduction. J Biol Chem 267:13,361-13,368
2. Adamson P, Hajimohammadreza I, Brammer MJ, Campbell IC, Meldrum BS (1990) Presynaptic glutamate/quisqualate receptors: Effects on synaptosomal free calcium concentrations. J Neurochem 55:1,850-1,854
3. Bhardwaj A, Northington FJ, Kochler RC, Hanley DF, Traystman RJ (1994) In-vivo characterization of nitric oxide (NO) production in the hippocampus with N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor stimulation and blockade [Abstract). Neurosci Abstr 20:278.7
4. Bhardwaj A, Northington FJ, Traystman RJ, Hanley DF, Koehler RC (1995a) Characterization of N-Methyl-D-Aspartate induced nitric oxide production: An in vivo microdialysis study [Abstract] Neurology 45:A391
5. Bhardwaj A, Northington FJ, Koehler RC, Stiefel T, Hanley DF, Traystman RJ (1995b) Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo. Stroke 26:1,627-1,633
6. Bilcioglu A, Maher TJ (1993) Determination of kainic acid-induced release of NO using a novel hemoglobin trapping technique with microdialysis. J Neurochem 61:2,311-2,313
7. Bolshakov VY, Siegelbaum SA (1994) Postsynaptic induction and presynaptic expression of hippocampal long-term depression. Science 264:1,148-1,152
8. Boss V, Conn JP (1992) Metabotropic excitatory amino acid receptor activation stimulates phospholipase D in hippocampal slices. J Neurochem 59:2,340-2,343
9. 2+ influx. Exp Brain Res 76:281-291
10. Bredt DS, Snyder SH (1990) Isolation of nitric oxide synthase, a calmodulin-requiring enzyme. Proc Natl Acad Sci U S A 87:682-685
11. Bredt DS, Glatt CE, Hwang PM, Fotuhi M, Dawson TM, Snyder SH (1991) Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of mammalian CNS together with NADPH diaphorase. Neuron 7:615-624
12. Dinerman JL, Dawson TM, Schell MJ, Snowman A, Snyder SH (1994) Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity. Proc Natl Acad Sci 91:4,214-4,218
13. Dun NJ, Dun SL, Wong RKS, Forstermann U (1994) Co-localization of nitric oxide synthase and somatostatin immunoreactivity in rat dentate hilar neurons. Proc Natl Acad Sci U S A 91:2,955-2,959
14. Eaton SA, Jane DE, Jones P, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Roberts PJ (1993) Competitive antagonism at metabotropic receptors by (S)-4-carboxyphenylglycine and (RS)-α-methyl-4-carboxyphenylglycine. Eur J Pharmacol 244: 195-197
15. Endoh M, Maiese K, Wagner J (1994) Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res 651:92-100
16. 2+ release from intracellular stores in cultured cerebral cortical neurons. J Neurochem 56:1,075-1,078
17. Frandsen A, Schousboe A (1992) Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3(3-hydroxy-5-methylisoxazole-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc Natl Acad Sci U S A 89:2,590-2,594
18. Frandsen A, Schousboe A (1993) Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons. J Neurochem 60:1,202-1,211
19. Garthwaite J, Garthwaite G, Palmer RMJ, Moncada S (1989a) NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 172:413-416
20. Garthwaite J, Southam E, Anderton M (1989b) A kainate receptor linked to nitric oxide synthesis from arginine. J Neurochem 53:1,952-1,954
21. Holler T, Cappel E, Klein J, Loffelholz K (1993) Glutamate activates phospholipase D in hippocampal slices of newborn and adult rats. J Neurochem 61:1,569-1,572
22. Johnson RD, Justice JB (1983) Model studies for brain dialysis. Brain Res Bull 10:567-571
23. Katz B, Miledi R (1967) A study of synaptic transmission in the absence of nerve impulses. J Physiol (London) 192:407-436
24. Lacaille J, Mueller AL, Kunkel DD, Schwartzkroin PA (1987) Local circuit interactions between oriens/alveus interneurons and CA1 pyramidal cells in hippocampal slices: Electrophysiology and morphology. J Neurosci 7:1,979-1,993
25. Liu Y, Disterhoft JF, Slater NT (1993) Activation of metabotropic glutamate receptors induces long-term depression of GABAergic inhibition in hippocampus. J Neurophysiol 69:1,000-1,004
26. Lonart G, Alagarsamy S, Johnson KM (1993) (R,S)-α-amino-3- hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors mediate a calcium-dependent inhibition of the metabotropic glutamate receptor-stimulated formation of inositol 1,4,5-triphosphate. J Neurochem 60:1,739-1,745
27. Luo D, Leung E, Vincent SR (1994) Nitric oxide-dependent efflux of cGMP in rat cerebellar cortex: An in vivo microdialysis study. J Neurosci 14:263-271
28. Malinski T, Bailey F, Zhang ZG, Chopp M (1993). Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 13:355-358
29. Martin LJ, Blackstone CD, Huganir RL, Price DL (1992) Cellular localization of a metabotropic glutamate receptor in the rat brain. Neuron 9:259-270
30. Northington FJ, Tobin JR, Koehler RC, Traystman RJ (1995) In vivo production of nitric oxide correlates with NMDA-induced cerebral hyperemia in newborn sheep. Am J Physiol 269:H215-H221
31. Ohishi H, Shigemoto R, Nakanishi S, Mizuno N (1993) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study. J Comp Neurol 335:252-266
32. Okada D (1992) Two pathways of cyclic GMP production through glutamate receptor-mediated nitric oxide synthesis. J Neurochem 59:1,203-1,210
33. Palmer E, Monaghan DT, Cotman CW (1989) Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor. Eur J Pharmacol 166:585-587
34. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. 2nd ed. San Diego, Academic Press Inc
35. Schoepp DD, Conn JP (1993) Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol Sci 14:13-19
36. Schoepp DD, Johnson BG, Salhoff CR, McDonald JW, Johnston MV (1991) In vitro and in vivo pharmacology of trans- and cis-(±)-1-amino-1,3-cyclopentanedicarboxylic acid: Dissociation of metabotropic and ionotropic excitatory amino acid receptor effects. J Neurochem 56:1,789-1,796
37. 2+ release channels in rat brain. J Neurosci 13:3,051-3,063
38. Simmons ML, Murphy S (1992) Induction of nitric oxide synthase in glial cells. J Neurochem 59:897-905
39. 2+ responses to N-methyl-D-aspartate and depolarization in cerebellar granule cells. J Neurochem 61:760-763
40. Southam E, East SJ, Garthwaite J (1991) Excitatory amino acid receptors coupled to the nitric oxide/cyclic GMP pathway in rat cerebellum during development. J Neurochem 56:2,072-2,081
41. Vallebuona F, Raiteri M (1994) Extracellular cGMP in the hippocampus of freely moving rats as an index of nitric oxide (NO) synthase activity. J Neurosci 14:134-139
42. Vallebuona F, Raiteri M (1995) Age-related changes in the NMDA receptor/nitric oxide cGMP pathway in the hippocampus and cerebellum of freely moving rats subjected to trancerebral microdialysis. Eur J Neurosci 7:694-701
43. Valtschanoff JG, Weinberg RJ, Kharazia VN, Nakane M, Schmidt H (1993) Neurons in the rat hippocampus that synthesize nitric oxide. J Comp Neurol 331:111-121
44. 3H]arginine in cultured neurons: Characteristics and inhibition by nitric oxide synthase inhibitors. J Neurochem 61: 364-367
45. Winder DG, Conn JP (1992) Activation of metabotropic glutamate receptors in hippocampus increases cyclic AMP accumulation. J Neurochem 59:375-378
46. Zheng F, Gallagher JP (1992) Burst firing of rat septal neurons induced by 1S,3R-ACPD requires influx of extracellular calcium. Eur J Pharmacol 211:261-262