메뉴 건너뛰기




Volumn 28, Issue 1, 1996, Pages 41-49

Acute MPTP treatment produces no changes in mitochondrial complex activities and indices of oxidative damage in the common marmoset ex vivo one week after exposure to the toxin

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; DOPAMINE; UBIQUINONE;

EID: 0029656203     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(95)00063-E     Document Type: Article
Times cited : (27)

References (60)
  • 1
  • 2
    • 0026030199 scopus 로고
    • Biochemical mechanisms of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine toxicity. Could oxidative stress be involved in the brain?
    • Adams J. D. and Odunze I. N. (1991) Biochemical mechanisms of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine toxicity. Could oxidative stress be involved in the brain? Biochem. Pharmac. 41, 1099-1105.
    • (1991) Biochem. Pharmac. , vol.41 , pp. 1099-1105
    • Adams, J.D.1    Odunze, I.N.2
  • 5
    • 0027236406 scopus 로고
    • Chronic administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine to monkeys: Behavioural, morphological and biochemical correlates
    • Albanese A., Granata R., Gregori B., Piccardi M. P., Colsimo C. and Tonali P. (1993) Chronic administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine to monkeys: behavioural, morphological and biochemical correlates. Neuroscience 55, 823-832.
    • (1993) Neuroscience , vol.55 , pp. 823-832
    • Albanese, A.1    Granata, R.2    Gregori, B.3    Piccardi, M.P.4    Colsimo, C.5    Tonali, P.6
  • 6
    • 0028064964 scopus 로고
    • Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria : Evidence for a primary involvement of energy depletion
    • Bates T. E., Heales S. J. R., Davies E. E. C., Boakye P. and Clark J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria : evidence for a primary involvement of energy depletion. J. Neurochem. 63, 640-648.
    • (1994) J. Neurochem. , vol.63 , pp. 640-648
    • Bates, T.E.1    Heales, S.J.R.2    Davies, E.E.C.3    Boakye, P.4    Clark, J.B.5
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem. 72, 248-254.
    • (1976) Analyt. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0001496694 scopus 로고
    • A primate model of Parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
    • Burns R. S., Chiueh C. C., Markey S. P., Ebert M. H., Jacobowitz D. M. and Kopin I. J. (1983) A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. Proc. natn. Acad. Sci. U.S.A. 80, 4546-4550.
    • (1983) Proc. Natn. Acad. Sci. U.S.A. , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 9
    • 0025945089 scopus 로고
    • Rapid ATP loss caused by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in mouse brain
    • Chan P., DeLanney L. E., Irwin I., Langston J. W. and Di Monte D. (1991) Rapid ATP loss caused by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in mouse brain. J. Neurochem. 57, 348-351.
    • (1991) J. Neurochem. , vol.57 , pp. 348-351
    • Chan, P.1    DeLanney, L.E.2    Irwin, I.3    Langston, J.W.4    Di Monte, D.5
  • 10
    • 0027344407 scopus 로고
    • Role of dopamine autoxidation, hydroxyl radical generation and calcium overload in underlying mechanism involved in MPTP-induced parkinsonism
    • Chiueh C. C., Miyake H. and Peng M. T. (1993) Role of dopamine autoxidation, hydroxyl radical generation and calcium overload in underlying mechanism involved in MPTP-induced parkinsonism. Adv. Neurol. 60, 251-258.
    • (1993) Adv. Neurol. , vol.60 , pp. 251-258
    • Chiueh, C.C.1    Miyake, H.2    Peng, M.T.3
  • 11
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter M. W., Cooper J. M. and Schapira A. H. (1992) Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J. Neurochem. 58, 786-789.
    • (1992) J. Neurochem. , vol.58 , pp. 786-789
    • Cleeter, M.W.1    Cooper, J.M.2    Schapira, A.H.3
  • 13
    • 0026694525 scopus 로고
    • Glutathione in Parkinson's disease: A link between oxidative stress and mitochondrial damage
    • Di Monte D. A., Chan, P. and Sandy S. M. (1992) Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage. Ann. Neurol. 32, 111-115.
    • (1992) Ann. Neurol. , vol.32 , pp. 111-115
    • Di Monte, D.A.1    Chan, P.2    Sandy, S.M.3
  • 14
    • 0027234508 scopus 로고
    • Ubiquinol: An endogenous antioxidant in aerobic organisms
    • Ernster L. and Forsmark-Andrée P. (1993) Ubiquinol: an endogenous antioxidant in aerobic organisms. Clin. Invest. 71, 60-65.
    • (1993) Clin. Invest. , vol.71 , pp. 60-65
    • Ernster, L.1    Forsmark-Andrée, P.2
  • 16
    • 0025988085 scopus 로고
    • MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease
    • Molec. Pharmac. Sect.
    • Gerlach M., Riederer P., Przuntek H. and Youdim M. B. H. (1991) MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease. Eur. J. Pharmac. (Molec. Pharmac. Sect.) 208, 273-286.
    • (1991) Eur. J. Pharmac. , vol.208 , pp. 273-286
    • Gerlach, M.1    Riederer, P.2    Przuntek, H.3    Youdim, M.B.H.4
  • 17
    • 0028000825 scopus 로고
    • Altered brain metabolism of iron as a cause of neurodegenerative diseases?
    • Gerlach M., Ben-Shachar D., Riederer P. and Youdim M. B. H. (1994) Altered brain metabolism of iron as a cause of neurodegenerative diseases? J. Neurochem. 63, 793-807.
    • (1994) J. Neurochem. , vol.63 , pp. 793-807
    • Gerlach, M.1    Ben-Shachar, D.2    Riederer, P.3    Youdim, M.B.H.4
  • 18
    • 0027478197 scopus 로고
    • The thiobarbituric acid reflects susceptibility to oxygen induced lipid peroxidation in vitro rather than levels of lipid hydroperoxides in vivo: A methodological approach
    • Götz M. E., Dirr A., Freyberger A., Burger R. and Riederer P. (1993) The thiobarbituric acid reflects susceptibility to oxygen induced lipid peroxidation in vitro rather than levels of lipid hydroperoxides in vivo: a methodological approach. Neurochem. Int. 22, 255-262.
    • (1993) Neurochem. Int. , vol.22 , pp. 255-262
    • Götz, M.E.1    Dirr, A.2    Freyberger, A.3    Burger, R.4    Riederer, P.5
  • 19
    • 0027951044 scopus 로고
    • Effect of lipoic acid on redox state of coenzyme Q in mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrdine and diethyl-dithiocarbamate
    • Molec. Pharmac. Sect.
    • Götz M. E., Dirr A., Burger R., Janetzky B., Weinmüller M., Chan W. W., Chen S. C., Reichmann H., Rausch W. -D. and Riederer P. (1994a) Effect of lipoic acid on redox state of coenzyme Q in mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrdine and diethyl-dithiocarbamate. Eur. J. Pharmac. (Molec. Pharmac. Sect.) 266, 291-300.
    • (1994) Eur. J. Pharmac. , vol.266 , pp. 291-300
    • Götz, M.E.1    Dirr, A.2    Burger, R.3    Janetzky, B.4    Weinmüller, M.5    Chan, W.W.6    Chen, S.C.7    Reichmann, H.8    Rausch, W.D.9    Riederer, P.10
  • 20
    • 0027937548 scopus 로고
    • Oxidative stress : Free radical production in neural degeneration
    • Götz M. E., Künig G., Riederer P. and Youdim M. B. H. (1994b). Oxidative stress : free radical production in neural degeneration. Pharmac. Ther. 63, 37-122.
    • (1994) Pharmac. Ther. , vol.63 , pp. 37-122
    • Götz, M.E.1    Künig, G.2    Riederer, P.3    Youdim, M.B.H.4
  • 21
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. (1992). Reactive oxygen species and the central nervous system J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 22
    • 0028799706 scopus 로고
    • Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration
    • Heales S. J. R., Davies S. E. C., Bates T. E. and Clark J. B. (1995). Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochem. Res. 20, 31-38.
    • (1995) Neurochem. Res. , vol.20 , pp. 31-38
    • Heales, S.J.R.1    Davies, S.E.C.2    Bates, T.E.3    Clark, J.B.4
  • 23
    • 0024381035 scopus 로고
    • Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse
    • Heikkila R. E., Sieber B.-A., Manzino L. and Sonsalla P. K. (1989). Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Molec. Chem. Neuropath. 10, 171-183.
    • (1989) Molec. Chem. Neuropath. , vol.10 , pp. 171-183
    • Heikkila, R.E.1    Sieber, B.-A.2    Manzino, L.3    Sonsalla, P.K.4
  • 25
    • 0026352710 scopus 로고
    • +) within catecholaminergic neurons
    • +) within catecholaminergic neurons. Neurotoxicology 12, 285-302.
    • (1991) Neurotoxicology , vol.12 , pp. 285-302
    • Johannessen, J.N.1
  • 26
    • 0023576260 scopus 로고
    • The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its relevance to Parkinson's disease
    • Kinemuchi H., Fowler C. J. and Tipton K. F. (1987). The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its relevance to Parkinson's disease. Neurochem. Int. 11, 359-373.
    • (1987) Neurochem. Int. , vol.11 , pp. 359-373
    • Kinemuchi, H.1    Fowler, C.J.2    Tipton, K.F.3
  • 27
    • 77956999492 scopus 로고
    • Preparation and properties of soluble NADH dehydrogenase from cardiac muscle
    • King T. E. and Howard R. L. (1967). Preparation and properties of soluble NADH dehydrogenase from cardiac muscle. Meth. Enzym. 10, 275-294.
    • (1967) Meth. Enzym. , vol.10 , pp. 275-294
    • King, T.E.1    Howard, R.L.2
  • 28
    • 0026597186 scopus 로고
    • Electrochemical determination of femtomole amounts of free reduced and oxidized glutathione
    • Krien P. M., Margon V. and Kermici M. (1992). Electrochemical determination of femtomole amounts of free reduced and oxidized glutathione. J. Chromatogr. 576, 255-261.
    • (1992) J. Chromatogr. , vol.576 , pp. 255-261
    • Krien, P.M.1    Margon, V.2    Kermici, M.3
  • 29
    • 0021337873 scopus 로고
    • Selective nigral toxicity after administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey
    • Langston J. W., Forno L. S., Rebert C. S. and Irwin I. (1984). Selective nigral toxicity after administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey. Brain Res. 292, 390-394.
    • (1984) Brain Res. , vol.292 , pp. 390-394
    • Langston, J.W.1    Forno, L.S.2    Rebert, C.S.3    Irwin, I.4
  • 30
    • 0027486512 scopus 로고
    • Experimental Parkinson's disease in monkeys. Effect of ergort alkaloid derivative on lipid peroxidation in different brain areas
    • Marzatico F., Café C., Taborelli M. and Benzi G. (1993). Experimental Parkinson's disease in monkeys. Effect of ergort alkaloid derivative on lipid peroxidation in different brain areas. Neurochem. Res. 18, 1101-1106.
    • (1993) Neurochem. Res. , vol.18 , pp. 1101-1106
    • Marzatico, F.1    Café, C.2    Taborelli, M.3    Benzi, G.4
  • 32
    • 0026720018 scopus 로고
    • Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes
    • Mithöfer K., Sandy M. S., Smith M. T. and Di Lonte D. (1992). Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes. Archs Biochem. Biophys. 295, 132-136.
    • (1992) Archs Biochem. Biophys. , vol.295 , pp. 132-136
    • Mithöfer, K.1    Sandy, M.S.2    Smith, M.T.3    Di Lonte, D.4
  • 33
    • 0023186383 scopus 로고
    • Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain
    • Mizuno Y., Sone N. and Saitoh T. (1987). Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain. J. Neurochem. 48, 1787-1793.
    • (1987) J. Neurochem. , vol.48 , pp. 1787-1793
    • Mizuno, Y.1    Sone, N.2    Saitoh, T.3
  • 34
    • 0023694019 scopus 로고
    • Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain in vivo
    • Mizuno Y., Susuki K., Sone N. and Saitoh T. (1988). Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain in vivo. Neurosci. Lett. 91, 349-353.
    • (1988) Neurosci. Lett. , vol.91 , pp. 349-353
    • Mizuno, Y.1    Susuki, K.2    Sone, N.3    Saitoh, T.4
  • 35
    • 0024589671 scopus 로고
    • Mitochondria covered with a net of parallel and latticed filaments in nigral neurons of monkeys with experimental parkinsonism
    • Nakamura H., Kato S. and Tanaka J. (1989). Mitochondria covered with a net of parallel and latticed filaments in nigral neurons of monkeys with experimental parkinsonism. Acta Neuropath. 77, 489-493.
    • (1989) Acta Neuropath. , vol.77 , pp. 489-493
    • Nakamura, H.1    Kato, S.2    Tanaka, J.3
  • 36
    • 0021810979 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenylpyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Nicklas W. J., Vyas I. and Heikkila R. E. (1985). Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenylpyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Life Sci. 36, 2503-2508.
    • (1985) Life Sci. , vol.36 , pp. 2503-2508
    • Nicklas, W.J.1    Vyas, I.2    Heikkila, R.E.3
  • 38
    • 0027361063 scopus 로고
    • Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse
    • P.-D.Sect.
    • Oishi T., Hasegawa E. and Murai Y. (1993). Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. J. Neural Transm. (P.-D.Sect.) 6, 45-52.
    • (1993) J. Neural Transm. , vol.6 , pp. 45-52
    • Oishi, T.1    Hasegawa, E.2    Murai, Y.3
  • 39
    • 0020398594 scopus 로고
    • A method for quantitative extraction of enzymes and metabolites from tissue samples in the milligram range
    • Pette D. and Reichmann H. (1982). A method for quantitative extraction of enzymes and metabolites from tissue samples in the milligram range. J. Histochem. Cytochem. 30, 401-402.
    • (1982) J. Histochem. Cytochem. , vol.30 , pp. 401-402
    • Pette, D.1    Reichmann, H.2
  • 40
    • 0023503459 scopus 로고
    • +, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase
    • +, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase. Archs Biochem. Biophys. 259, 645-649.
    • (1987) Archs Biochem. Biophys. , vol.259 , pp. 645-649
    • Ramsay, R.R.1    Kowal, A.T.2    Johnson, M.D.3    Salach, J.I.4    Singer, T.P.5
  • 41
    • 0021837948 scopus 로고
    • Biochemical and structural changes of skeletal muscle mitochondria after chronic electrical stimulation in rabbits
    • Reichmann H., Hoppeler H., Matthieu-Costello O., von Bergen F. and Pette D. (1985) Biochemical and structural changes of skeletal muscle mitochondria after chronic electrical stimulation in rabbits. Pflügers Arch. 404, 1-9.
    • (1985) Pflügers Arch. , vol.404 , pp. 1-9
    • Reichmann, H.1    Hoppeler, H.2    Matthieu-Costello, O.3    Von Bergen, F.4    Pette, D.5
  • 42
    • 0027356272 scopus 로고
    • Parkinson's disease and the electron transport chain in post mortem brain
    • Narabayashi H., Nagatsu T., Yanagisawa N. and Mizuno Y., eds, Raven Press, New York
    • Reichmann H., Lestienne P., Jellinger K. and Riederer P. (1993) Parkinson's disease and the electron transport chain in post mortem brain. In Advances in Neurology, (Narabayashi H., Nagatsu T., Yanagisawa N. and Mizuno Y., eds), Vol. 60, pp. 297-299. Raven Press, New York.
    • (1993) Advances in Neurology , vol.60 , pp. 297-299
    • Reichmann, H.1    Lestienne, P.2    Jellinger, K.3    Riederer, P.4
  • 44
    • 0026099265 scopus 로고
    • Neurochemical and behavioural features induced by chronic low dose treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset: Implications for Parkinson's disease?
    • Russ H., Mihatsch W., Gerlach M., Riederer P. and Przuntek H. (1991) Neurochemical and behavioural features induced by chronic low dose treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset: implications for Parkinson's disease? Neurosci. Lett. 123, 115-118.
    • (1991) Neurosci. Lett. , vol.123 , pp. 115-118
    • Russ, H.1    Mihatsch, W.2    Gerlach, M.3    Riederer, P.4    Przuntek, H.5
  • 45
    • 0026696122 scopus 로고
    • Effects of cryopreservation on survival and function of intrastriatal fetal mesencephalic grafts
    • Sauer H., Frodl E. M., Kupsch A., ten Bruggencate G. and Oertel W. H. (1992) Effects of cryopreservation on survival and function of intrastriatal fetal mesencephalic grafts. Exp. Brain Res. 90, 54-62.
    • (1992) Exp. Brain Res. , vol.90 , pp. 54-62
    • Sauer, H.1    Frodl, E.M.2    Kupsch, A.3    Ten Bruggencate, G.4    Oertel, W.H.5
  • 46
    • 0024349630 scopus 로고
    • Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Sayre L. M. (1989) Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxic. Lett. 48, 121-149.
    • (1989) Toxic. Lett. , vol.48 , pp. 121-149
    • Sayre, L.M.1
  • 47
    • 0028274216 scopus 로고
    • Review: Evidence for mitochondrial dysfunction in Parkinson's disease - A critical appraisal
    • Schapira A. H. V. (1994) Review: evidence for mitochondrial dysfunction in Parkinson's disease - a critical appraisal. Mov. Disord. 9, 125-138.
    • (1994) Mov. Disord. , vol.9 , pp. 125-138
    • Schapira, A.H.V.1
  • 49
    • 0023142883 scopus 로고
    • Reduced and oxidized glutathione in human and monkey brain
    • Slivka A., Spina M. B. and Cohen G. (1987) Reduced and oxidized glutathione in human and monkey brain. Neurosci. Lett. 74, 112-118.
    • (1987) Neurosci. Lett. , vol.74 , pp. 112-118
    • Slivka, A.1    Spina, M.B.2    Cohen, G.3
  • 50
    • 0026644192 scopus 로고
    • Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
    • Sofic E., Lange K. W., Jellinger K. and Riederer P. (1992) Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci. Lett. 142, 128-130.
    • (1992) Neurosci. Lett. , vol.142 , pp. 128-130
    • Sofic, E.1    Lange, K.W.2    Jellinger, K.3    Riederer, P.4
  • 52
    • 0026719208 scopus 로고
    • 1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism
    • Storey E., Hyman B. T., Jenkins B., Brouillet E., Miller J. M., Rosen B. R. and Beal M. F. (1992) 1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism. J. Neurochem. 58, 1975-1978.
    • (1992) J. Neurochem. , vol.58 , pp. 1975-1978
    • Storey, E.1    Hyman, B.T.2    Jenkins, B.3    Brouillet, E.4    Miller, J.M.5    Rosen, B.R.6    Beal, M.F.7
  • 53
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton K. and Singer T. P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem. 61, 1191-1206.
    • (1993) J. Neurochem. , vol.61 , pp. 1191-1206
    • Tipton, K.1    Singer, T.P.2
  • 54
    • 0026757291 scopus 로고
    • Mitochondrial factors involved in Parkinson's disease by MPTP toxicity in Macaca fascicularis and drug effect
    • Villa R. F., Arnaboldi R., Ghigini B. and Gorini A. (1992) Mitochondrial factors involved in Parkinson's disease by MPTP toxicity in Macaca fascicularis and drug effect. Neurochem. Res. 17, 1147-1154.
    • (1992) Neurochem. Res. , vol.17 , pp. 1147-1154
    • Villa, R.F.1    Arnaboldi, R.2    Ghigini, B.3    Gorini, A.4
  • 55
    • 0020321824 scopus 로고
    • Simultaneous determination of 3,4,-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindole acetic acid in rat cerebrospinal fluid and brain by high performance liquid chromatography with electrochemical detection
    • Wagner J., Vitali P., Palfreyman M. G., Zraika M. and Hout S. (1982) Simultaneous determination of 3,4,-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindole acetic acid in rat cerebrospinal fluid and brain by high performance liquid chromatography with electrochemical detection. J. Neurochem. 38, 1241-1254.
    • (1982) J. Neurochem. , vol.38 , pp. 1241-1254
    • Wagner, J.1    Vitali, P.2    Palfreyman, M.G.3    Zraika, M.4    Hout, S.5
  • 56
    • 0026071272 scopus 로고
    • Intramitochondrial formation of oxidized glutathione during the oxidation of benzylamine by monoamine oxidase
    • Werner P. and Cohen G. (1991) Intramitochondrial formation of oxidized glutathione during the oxidation of benzylamine by monoamine oxidase. FEBS Lett. 280, 44-46.
    • (1991) FEBS Lett. , vol.280 , pp. 44-46
    • Werner, P.1    Cohen, G.2
  • 57
    • 0001884644 scopus 로고
    • Individual comparisons by ranking methods
    • Wilcoxon F. (1945) Individual comparisons by ranking methods. Biometrics 1, 80-83.
    • (1945) Biometrics , vol.1 , pp. 80-83
    • Wilcoxon, F.1
  • 59
    • 0027351360 scopus 로고
    • The neurotoxicity of iron and nitric oxide: Relevance to the etiology of Parkinson's disease
    • Narabayashi H., Nagatsu T., Yanagisawa N. and Mizuno Y., eds, Raven Press, New York
    • Youdim M. B. H., Ben-Shachar D., Eshel G., Finberg J. P. M. and Riederer P. (1993) The neurotoxicity of iron and nitric oxide: relevance to the etiology of Parkinson's disease. In Advances in Neurology, (Narabayashi H., Nagatsu T., Yanagisawa N. and Mizuno Y., eds), Vol. 60, pp. 259-266. Raven Press, New York.
    • (1993) Advances in Neurology , vol.60 , pp. 259-266
    • Youdim, M.B.H.1    Ben-Shachar, D.2    Eshel, G.3    Finberg, J.P.M.4    Riederer, P.5
  • 60
    • 0026752794 scopus 로고
    • MK-801 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in primates
    • Zuddas A., Oberto G., Vaglini F., Fascetti F., Fornai F. and Corsini G. U. (1992) MK-801 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in primates. J. Neurochem. 59, 733-739.
    • (1992) J. Neurochem. , vol.59 , pp. 733-739
    • Zuddas, A.1    Oberto, G.2    Vaglini, F.3    Fascetti, F.4    Fornai, F.5    Corsini, G.U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.