Topology of CD38

Chemical Immunology

Volumn 75, Issue , 2000, Pages 79-98

  De Flora, Antonio ^a   Franco, Luisa ^a   Guida, Lucrezia ^a   Bruzzone, Santina ^a   Usai, Cesare ^b   Zocchi, Elena ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE DIPHOSPHATE RIBOSYL CYCLASE; CALCIUM ION; CARRIER PROTEIN; CD38 ANTIGEN; CELL SURFACE RECEPTOR; MEMBRANE ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

CALCIUM MOBILIZATION; CONFERENCE PAPER; ENZYME LOCALIZATION; INTERNALIZATION; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN TRANSPORT;

EID: 0033974722     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: 10.1159/000058764     Document Type: Conference Paper

References (33)

1. Mehta K, Shahid U, Malavasi F: Human CD38, a cell-surface protein with multiple functions. FASEB J 1996;10:1408-1417.
2. Deaglio S, Morra M, Mallone R, Ausiello CM, Prager E, Garbarino G, Dianzani U, Stockinger H, Malavasi F: Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member. J Immunol 1998;160:395-402.
3. Kontani K, Kukimoto I, Nishina H, Hoshino S, Hazeki O, Kanaho Y, Katada T: Tyrosine phosphorylation of c-cbl proto-oncogene product mediated by cell surface antigen CD38 in HL60 cells. J Biol Chem 1996;271:1534-1537.
4. Silvennoinen O, Nishigaki H, Kitanaka A, Kumagai M, Ito C, Malavasi F, Lin Q, Conley ME, Campana D: CD38 signal transduction in human B cell precursors. J Immunol 1996;156:100-107.
5. Lee HC, Graeff R, Walseth TF: Cyclic ADP-ribose and its metabolic enzymes. Biochimic 1995;77: 345-355.
6. Lee HC: Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP. Physiol Rev 1997; 77:1134-1164.
7. De Flora A, Guida L, Franco L, Zocchi E, Bruzzone S, Benatti U, Damonte G, Lee HC: CD38 and ADP-ribosyl cyclase catalyze the synthesis of a dimeric ADP-ribose that potentiates the calcium-mobilizing activity of cyclic ADP-ribose. J Biol Chem 1997;272:12945-12951.
8. Lee HC, Galione A, Walseth TF: Cyclic ADP-ribose: Metabolism and calcium mobilizing function; in Litwack G (ed): Vitamins and Hormones. Orlando, Academic Press, 1994, vol 48, pp 199-254.
9. Kontani K, Nishina H, Ohoka J, Takahashi K, Katada T: NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells: Identification of the NAD glycohydrolase as leukocyte cell surface antigen CD38. J Biol Chem 1993;268:16895-16898.
10. De Flora A, Guida L, Franco L, Zocchi E: The CD38/cyclic ADP-ribose system: A topological paradox. Int J Biochem Cell Biol 1997;29:1149-1166.
11. 2+-mobilizing activity of cyclic ADP-ribose. Cell Biochem Biophys 1998;28: 45-62.
12. Lund FE, Cockayne DA, Randall TD, Solvason N, Schuber F, Howard MC: CD38: A new paradigm in lymphocyte activation and signal transduction. Immunol Rev 1998;161:79-93.
13. Lee HC, Zocchi E, Guida L, Franco L, Benatti U, De Flora A: Production and hydrolysis of cyclic ADP-ribose at the outer surface of human erythrocytes. Biochem Biophys Res Commun 1993;191: 639-645.
14. Zocchi E, Daga A, Usai C, Franco L, Guida L, Bruzzone S, Costa A, Marchetti C, De Flora A: Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. J Biol Chem 1998;273:8017-8024.
15. Howard M, Grimaldi JC, Bazan JF, Lund FE, Santos-Argumedo L, Parkhouse RME, Walseth TF, Lee HC: Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 1993;262:1056-1059.
16. De Flora A, Guida L, Franco L, Zocchi E, Pestarino M, Usai C, Marchetti C, Fedele E, Fontana G, Raiteri M: Ectocellular in vitro and in vivo metabolism of cyclic ADP-ribose in cerebellum. Biochem J 1996;320:665-672.
17. +-dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells. FEES Lett 1996;396:327-332.
18. Funaro A, Reiniš M, Trubiani O, Santi S, Di Primio R, Malavasi F: CD38 functions are regulated through an internalization step. J Immunol 1998;160:2238-2247.
19. Franco L, Zocchi E, Calder L, Guida L, Benatti U, De Flora A: Self-aggregation of the transmembrane glycoprotein CD38 purified from human erythrocytes. Biochem Biophys Res Commun 1994; 202:1710-1718.
20. Guida L, Franco L, Zocchi E, De Flora A: Structural role of disulfide bridges in the cyclic ADP-ribose related bifunctional ectoenzyme CD38. FEBS Lett 1995;368:481-484.
21. Zocchi E, Franco L, Guida L, Calder L, De Flora A: Self-aggregation of purified and membrane-bound erythrocyte CD38 induces extensive decrease of its ADP-ribosyl cyclase activity. FEBS Lett 1995;359:35-10.
22. Tohgo A, Takasawa S, Noguchi N, Koguma T, Nata K, Sugimoto T, Furuya Y, Yonekura H, Okamoto H: Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38. J Biol Chem 1994;269:28555-28557.
23. Prasad GS, McRee DE, Stura EA, Levitt DG, Lee HC, Stout CD: Crystal structure of Aplysia ADP-ribosyl cyclase, a homologue of the bifunctional ectoenzyme CD38. Nat Struct Biol 1996;3: 957-967.
24. Lund F, Solvason N, Grimaldi JC, Parkhouse RME, Howard M: Murine CD38: An immunoregulatory ectoenzyme. Immunol Today 1995;16:469-473.
25. Graeff RM, Franco L, De Flora A, Lee HC: Cyclic GMP dependent and independent effects on the synthesis of the calcium messengers cyclic ADP-ribose and NAADP. J Biol Chem 1998;273: 118-125.
26. Franco L, Guida L, Bruzzone S, Zocchi E, Usai C, De Flora A: The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB J 1998;12:1507-1520.
27. Graeff RM, Walseth TF, Fryxell K, Branton DW, Lee HC: Enzymatic synthesis and characterization of cyclic GDP-ribose. J Biol Chem 1994;269:30260-30267.
28. Bruzzone S, Guida L, Franco L, Zocchi E, Corte G, De Flora A: Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells. FEBS Lett 1998;433:275-278.
29. + transport across cell membranes. FASEB J 1999;13:273-283.
30. Ueda K, Hayaishi O: Leukemia and cancer; in Hayaishi O, Ueda K (eds): ADP-Ribosylation Reactions. Biology and Medicine. New York, Academic Press, 1982, pp 561-572.
31. 2+], in porcine tracheal smooth muscle. Am J Physiol 1998;274:C1653-C1660.
32. Meldolesi J: Oscillation, activation, expression. Nature 1998;392:863-866.
33. Kaisho T, Ishikawa J, Oritani K, Inazawa J, Tomizawa H, Murcoka O, Ochi T, Hirano T: BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth. Proc Natl Acad Sci USA 1994;91:5325-5329.