Ligand-induced internalization of CD38 results in intracellular Ca2+ mobilization: Role of NAD+ transport across cell membranes

FASEB Journal

Volumn 13, Issue 2, 1999, Pages 273-283

  Zocchi, Elena ^a   Usai, Cesare ^b   Guida, Lucrezia ^a   Franco, Luisa ^a   Bruzzone, Santina ^a   Passalacqua, Mario ^a   De Flora, Antonio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b CNR   (Italy)

Author keywords

Cyclic ADP ribose; Intracellular calcium homeostasis; NAD+ transporter; Pyridine nucleotides

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; CALCIUM ION; CARRIER PROTEIN; CD38 ANTIGEN; LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRIDINE NUCLEOTIDE;

ARTICLE; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECOND MESSENGER;

VERTEBRATA;

EID: 0033005753     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.2.273     Document Type: Article

References (43)

1. Jackson, D. G., and Bell, J. I. (1990) Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. J. Immunol. 144, 2811-2817
2. Malavasi, F., Funaro, A., Roggero, S., Horenstein, A., Calosso, L., and Mehta, K. (1994) Human CD38: a glycoprotein in search of a function. Immunol. Today 15, 95-97
3. Lund, F., Solvason, N., Grimaldi, J. C., Parkhouse, R. M. E., and Howard, M. (1995) Murine CD38: an immunoregulatory ectoenzyme. Immunol. Today 16, 469-473
4. Mehta, K., Shahid, U., and Malavasi F. (1996) Human CD38, a cell-surface protein with multiple functions. FASEB J. 10, 1408-1417
5. Lee, H. C., Graeff, R., and Walseth, T. F. (1995) Cyclic ADP-ribose and its metabolic enzymes. Biochimie 77, 345-355
6. De Flora, A., Guida, L., Franco, L., Zocchi, E., Pestarino, M., Usai, C., Marchetti, C., Fedele, E., Fontana, G., and Raiteri, M. (1996) Ectocellular in vitro and in vivo metabolism of cADP-ribose in cerebellum. Biochem. J. 320, 665-672
7. Takasawa, S., Tohgo, A., Noguchi, N., Koguma, T., Nata, K., Sugimoto, T., Yonekura, H., and Okamoto, S. (1993) Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of hydrolysis by ATP. J. Biol. Chem. 268, 26052-26054
8. + glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes.Biochem. Biophys. Res. Commun. 196, 1459-1465
9. Howard, M., Grimaldi, J. C., Bazan, J. F., Lund, F. E., Santos-Argumedo, L., Parkhouse, R. M. E., Walseth, T. F., and Lee, H. C. (1993) Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 262, 1056-1059
10. Kontani, K., Nishina, H., Ohoka, J., Takahashi, K., and Katada, T. (1993) NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells: identification of the NAD glycohydrolase as leukocyte cell surface antigen CD38. J. Biol. Chem. 268, 16895-16898
11. Summerhill, R. J., Jackson, D. G., and Galione, A. (1993) Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose. FEBS Lett. 355, 231-233
12. Aarhus, R., Graeff, R. M., Dickey, D. M., Walseth, T. F., and Lee, H. C. (1995) ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium mobilizing metabolite from NADP. J. Biol. Chem. 270, 30327-30334
13. Lee, H. C. (1997) Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP. Physiol. Rev. 77, 1133-1164
14. 2+ signaling. In: ADP-Ribosylation in Animal Tissues (Haag, F., and Koch-Nolte, F., eds) pp. 411-419, Plenum Press, New York
15. Wu, Y., Kuzma, J., Marechal, E., Graeff., R., Lee, H. C., Foster, R., and Chua, N. H. (1997) Abscisic acid signaling through cyclic ADP-ribose in plants. Science 278, 2126-2129
16. 2+ mobilizing activity. J. Biol. Chem. 264, 1608-1615
17. Lee, H. C., Galione, A., and Walseth, T. F. (1994) Cyclic ADP-ribose: metabolism and calcium mobilizing function. In: Vitamins and Hormones (Litwack, G., ed) Vol. 48, pp. 199-258, Academic Press, Orlando, Florida
18. Carafoli, E. (1987) Intracellular calcium homeostasis. Annu. Rev. Biochem. 56, 395-433
19. De Flora, A., Guida, L., Franco, L., and Zocchi, E. (1997) The CD38/cyclic ADP-ribose system: a topological paradox. Int. J. Biochem. Cell. Biol. 29, 1149-1166
20. 2+-mobilizing activity of cyclic ADP-ribose. Cell Biochem. Biophys. 28, 45-62
21. +-dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells. FEBS Lett. 369, 327-332
22. Franco, L., Guida, L., Bruzzone, S., Zocchi, E., Usai, C., and De Flora, A. (1998) The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB J. 13, 1507-1520
23. Zocchi, E., Daga, A., Usai, C., Franco., L., Guida, L., Bruzzone, S., Costa, A., Marchetti, C., and De Flora, A. (1998) Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. J. Biol. Chem. 273, 8017-8024
24. Lee, H. C. (1991) Specific binding of cyclic ADP-ribose to calcium-storing microsomes from sea urchin eggs. J. Biol. Chem. 266, 2276-2281
25. Lee, H. C., Aarhus, R., and Walseth, T. F. (1993) Calcium mobilization by dual receptors during fertilization of sea urchin eggs. Science 261, 352-355
26. Walseth, T. F., Aarhus, R., Kerr, J. A., and Lee, H. C. (1993) Identification of cyclic ADP-ribose binding proteins by photoaffinity labeling. J. Biol. Chem. 268, 26686-26691
27. Lee, H. C., Aarhus, R., Graeff, R., Guarnack, M. E., and Walseth, T. F. (1994) Cyclic ADP-ribose activation of the ryanodine receptor is mediated by calmodulin. Nature (London) 370, 307-309
28. 2+ release. Biochim. Biophys. Acta 1178, 235-242
29. Walseth, T. F., Aarhus, R., Gurnack, M. E., Wong, L., Breitinger, H.-G., Gee, K. R., and Lee, H.C. (1997) Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP-ribose. In: Methods in Enzymology (Abelson, J. N., and Simon, M. I., eds) Vol. 280, 294-305
30. Higgings, D. G., and Sharp, P. M. (1988) CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. Gene 73, 237-244
31. Bradford, M. (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biorhem. 72, 248-252
32. Beutler, E. (1984) Red Cell Metabolism: A Manual of Biochemical Methods, 3rd Ed, Grune & Stratton, New York
33. Zerez, C. R., Lee, S. J., and Tanaka, K. R. (1987) Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure. Anal. Biochem. 164, 367-373
34. Guida, L., Franco, L., Zocchi, E., and De Flora, A. (1995) Structural role of disulfide bridges in cyclic ADP-ribose related bifunctional ectoenzyme CD38. FEBS Lett. 368, 481-484
35. Bruzzone, S., Guida, L., Franco, L., Zocchi, E., Corte, G., and De Flora, A. (1998) Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells. FEBS Lett. 433, 275-278
36. Stryer, L. (1995) Biochemistry, 4th Ed, W.H. Freeman and Company, New York
37. + between intact isolated plant mitochondria and suspending medium. Biochem. J. 216, 443-450
38. Rustin, P., Parfait, B., Chretien, D., Bourgeron, T., Djouadi, F., Bastin, J., Rōtig, A., and Munnich, A. (1996) Fluxes of Nicotinamide adenine dinucleotides through mitochondrial membranes in human cultured cells. J. Biol. Chem. 271, 14785-14790
39. Haley, B. E. (1991) Nucleotide photoaffinity labeling of protein kinase subunits. In: Methods in Enzymology (Hunter, T., and Sefton, B. M., eds) Vol. 200, 477-487
40. Zupo, S., Rugarli, S., Dono, M., Tamborelli, G., Malavasi, F., and Ferrarini, M. (1994) CD38 signalling by agonistic monoclonal antibodies prevents apoptosis of human germinal center B cells. Eur. J. Immunol. 24, 1218-1222
41. Dolmetsch, R. E., Xu, K., and Lewis, R. S. (1998) Calcium oscillation increase the efficiency and specificity of gene expression. Nature (London) 392, 933-936
42. 2+ spike frequency can optimize gene expression. Nature (London) 392, 936-941
43. Meldolesi, J. (1998) Oscillation, activation, expression. Nature (London) 392, 863-866