-
1
-
-
0027249519
-
Evaluating the effect of P210 BCR/ABL on growth of hematopoietic progenitor cells and its role in the pathogenesis of human chronic myelogenous leukemia
-
Gishizky, M. L., Johnson-White, J., and Witte, O. N. Evaluating the effect of P210 BCR/ABL on growth of hematopoietic progenitor cells and its role in the pathogenesis of human chronic myelogenous leukemia. Semin. Hematol., 30: 6-8, 1993.
-
(1993)
Semin. Hematol.
, vol.30
, pp. 6-8
-
-
Gishizky, M.L.1
Johnson-White, J.2
Witte, O.N.3
-
2
-
-
0032999728
-
Chronic myelogenous leukemia. Update on biology and treatment
-
Faderl, S., Kantaijian, H. M., and Talpaz, M. Chronic myelogenous leukemia. Update on biology and treatment. Oncology, 13: 169-180, 1999.
-
(1999)
Oncology
, vol.13
, pp. 169-180
-
-
Faderl, S.1
Kantaijian, H.M.2
Talpaz, M.3
-
3
-
-
0033614446
-
Chronic myeloid leukemia
-
Sawyers, C. L. Chronic myeloid leukemia. N. Engl. J. Med., 340: 1330-1340, 1999.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
4
-
-
0025117392
-
bcr/abl gene of the Philadelphia chromosome
-
Washington DC
-
bcr/abl gene of the Philadelphia chromosome. Science (Washington DC), 247: 824-830, 1990.
-
(1990)
Science
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
Van Etten, R.A.2
-
5
-
-
0025271543
-
Bcr-abl, the hallmark of chronic myeloid leukaemia in man, induced multiple haemopoietic neoplasms in mice
-
Elfanty, A. G., Hariharan, I. K., and Cory, S. Bcr-abl, the hallmark of chronic myeloid leukaemia in man, induced multiple haemopoietic neoplasms in mice. EMBO J., 9: 1069-1078, 1990.
-
(1990)
EMBO J.
, vol.9
, pp. 1069-1078
-
-
Elfanty, A.G.1
Hariharan, I.K.2
Cory, S.3
-
6
-
-
0025187837
-
Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL
-
Kelliher, M. A., McLaughlin, J., Witte, O. N., and Rosenberg, N. Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL. Proc. Natl. Acad. Sci. USA, 87: 6649-6653, 1990.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6649-6653
-
-
Kelliher, M.A.1
McLaughlin, J.2
Witte, O.N.3
Rosenberg, N.4
-
7
-
-
0032533257
-
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/ abl-transduced bone marrow
-
Pear, W. S., Miller, J. P., Zu, L., Pui, J. C., Soffer, B., Quackenbush, R. C., Pendergast, A. M., Bronson, R., Aster, J. C., Scott, M. L., and Baltimore, D. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/ abl-transduced bone marrow. Blood, 92: 3780-3792, 1998.
-
(1998)
Blood
, vol.92
, pp. 3780-3792
-
-
Pear, W.S.1
Miller, J.P.2
Zu, L.3
Pui, J.C.4
Soffer, B.5
Quackenbush, R.C.6
Pendergast, A.M.7
Bronson, R.8
Aster, J.C.9
Scott, M.L.10
Baltimore, D.11
-
8
-
-
0024353722
-
The mouse Type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
-
Van Etten, R. A., Jackson, P., and Baltimore, D. The mouse Type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell, 58: 669-678, 1989.
-
(1989)
Cell
, vol.58
, pp. 669-678
-
-
Van Etten, R.A.1
Jackson, P.2
Baltimore, D.3
-
9
-
-
0025038410
-
BCR-ABL and BCR proteins. Biochemical characterization and localization
-
Baltimore
-
Dhut, S., Chaplin, T., and Young, B. D. BCR-ABL and BCR proteins. Biochemical characterization and localization. Leukemia (Baltimore), 4: 745-750, 1990.
-
(1990)
Leukemia
, vol.4
, pp. 745-750
-
-
Dhut, S.1
Chaplin, T.2
Young, B.D.3
-
10
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of Bcr-Abl oncogene products
-
Washington DC
-
Lugo, T. G., Pendergast, A. M., Muller, A. J., and Witte, O. N. Tyrosine kinase activity and transformation potency of Bcr-Abl oncogene products. Science (Washington DC), 247: 1079-1082, 1990.
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
11
-
-
0031105070
-
Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL
-
Sattler, M., and Salgia, R. Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL. Cytokine Growth Factor Reviews, 8: 63-79, 1997.
-
(1997)
Cytokine Growth Factor Reviews
, vol.8
, pp. 63-79
-
-
Sattler, M.1
Salgia, R.2
-
12
-
-
0031038744
-
The function of BCR/ABL and related proto-oncogenes
-
Gotoh, A., and Broxmeyer, H. E. The function of BCR/ABL and related proto-oncogenes. Curr. Opin. Hematol., 4: 3-11, 1997.
-
(1997)
Curr. Opin. Hematol.
, vol.4
, pp. 3-11
-
-
Gotoh, A.1
Broxmeyer, H.E.2
-
13
-
-
0030725775
-
The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates Gl-to-S phase transition in hematopoietic cells
-
Cortez, D., Reuther, G., and Pendergast, A. M. The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates Gl-to-S phase transition in hematopoietic cells, Oncogene, 15: 2333-2342, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 2333-2342
-
-
Cortez, D.1
Reuther, G.2
Pendergast, A.M.3
-
14
-
-
0028181371
-
BCR/ABL expression in 32D c13 (G) cells inhibits apoptosis induced by protein tyrosine kinase inhibitors
-
Laneuville, P., Timm, M., and Hudson, A. T. BCR/ABL expression in 32D c13 (G) cells inhibits apoptosis induced by protein tyrosine kinase inhibitors. Cancer Res., 54: 1360-1366, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1360-1366
-
-
Laneuville, P.1
Timm, M.2
Hudson, A.T.3
-
15
-
-
0027979832
-
Bcr-Abl maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
-
McGahon, A., Bissonnette, R., Schmitt, M., Cotter, K. M., Green, D. R., and Cotter, T. G. Bcr-Abl maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood, 83: 1179-1187, 1994.
-
(1994)
Blood
, vol.83
, pp. 1179-1187
-
-
McGahon, A.1
Bissonnette, R.2
Schmitt, M.3
Cotter, K.M.4
Green, D.R.5
Cotter, T.G.6
-
16
-
-
0028256425
-
Inhibition of apoptosis by Bcr-Abl in chronic myeloid leukemia
-
Bedi, A., Zehnbauer, B. A., Barber, J. P., Sharkis, S. J., and Jones, R. J. Inhibition of apoptosis by Bcr-Abl in chronic myeloid leukemia. Blood, 83: 2038-2044, 1994.
-
(1994)
Blood
, vol.83
, pp. 2038-2044
-
-
Bedi, A.1
Zehnbauer, B.A.2
Barber, J.P.3
Sharkis, S.J.4
Jones, R.J.5
-
17
-
-
0029036445
-
The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors
-
Baltimore
-
Dubrez, L., Goldwasser, F., Genne, P., Pommier, Y., and Solary, E. The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors. Leukemia (Baltimore), 9: 1013-1024, 1995.
-
(1995)
Leukemia
, vol.9
, pp. 1013-1024
-
-
Dubrez, L.1
Goldwasser, F.2
Genne, P.3
Pommier, Y.4
Solary, E.5
-
18
-
-
0029852727
-
s induced differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-β-D-arabinofuranosylcytosine-mediated differentiation and apoptosis
-
s induced differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-β-D-arabinofuranosylcytosine-mediated differentiation and apoptosis. Cell Growth Differ., 7: 1617-1623, 1996.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 1617-1623
-
-
Ray, S.1
Bullock, G.2
Nunez, G.3
Tang, C.4
Ibrado, A.M.5
Huang, Y.6
Bhalla, K.7
-
19
-
-
0030471795
-
The BCR-ABL tyrosine kinase inhibits apoptosis by activating a ras-dependent signaling pathway
-
Cortez, D., Stoica, G., Pierce, J. H., and Pendergast, A. M. The BCR-ABL tyrosine kinase inhibits apoptosis by activating a ras-dependent signaling pathway. Oncogene, 13: 2589-2594, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 2589-2594
-
-
Cortez, D.1
Stoica, G.2
Pierce, J.H.3
Pendergast, A.M.4
-
20
-
-
0030701895
-
Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis
-
Martins, L. M., Mesner, P. W., Kottke, T. J., Basi, G. S., Sinha, S., Tung, J. S., Svingen, P. A., Madden, B. J., Takahashi, A., McCormick, D. J., Earnshaw, W. C., and Kaufmann, S. H. Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis. Blood, 90: 4283-4296, 1997.
-
(1997)
Blood
, vol.90
, pp. 4283-4296
-
-
Martins, L.M.1
Mesner, P.W.2
Kottke, T.J.3
Basi, G.S.4
Sinha, S.5
Tung, J.S.6
Svingen, P.A.7
Madden, B.J.8
Takahashi, A.9
McCormick, D.J.10
Earnshaw, W.C.11
Kaufmann, S.H.12
-
21
-
-
0032032270
-
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3
-
Amarante-Mendes, G. P., Kim, C. N., Liu, L., Huang, Y., Perkins, C., Green, D. R., and Bhalla, K. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood, 91: 1700-1705, 1998.
-
(1998)
Blood
, vol.91
, pp. 1700-1705
-
-
Amarante-Mendes, G.P.1
Kim, C.N.2
Liu, L.3
Huang, Y.4
Perkins, C.5
Green, D.R.6
Bhalla, K.7
-
22
-
-
0032055535
-
Bcr-Abl delays apoptosis upstream of procaspase-3 activation
-
Dubrez, L., Eymin. B., Sordet, O., Droin, N., Turhan, A. G., and Solary, E. Bcr-Abl delays apoptosis upstream of procaspase-3 activation. Blood, 91: 2415-2422, 1998.
-
(1998)
Blood
, vol.91
, pp. 2415-2422
-
-
Dubrez, L.1
Eymin, B.2
Sordet, O.3
Droin, N.4
Turhan, A.G.5
Solary, E.6
-
23
-
-
0028980342
-
Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis
-
Cortez, D., Kadlec, L., and Pendergast, A. M. Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Mol. Cell. Biol., 15: 5531-5541, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5531-5541
-
-
Cortez, D.1
Kadlec, L.2
Pendergast, A.M.3
-
24
-
-
0028895008
-
Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation
-
Gishizky, M. L., Cortez, D., and Pendergast, A. M. Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation. Proc. Natl. Acad. Sci. USA, 92: 10889-10893, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10889-10893
-
-
Gishizky, M.L.1
Cortez, D.2
Pendergast, A.M.3
-
25
-
-
0029063970
-
Phosphatidylinositol 3-kinase activity is regulated by Bcr/Abl and is required for the growth of Philadelphia chromosome-positive cells
-
Skorski, T., Kanakaraj, P., Nieborowska-Skorska, M., Ratajczak, M. Z., Wen, S. C., Zon, G., Gerwirtz, A. M., Perussia, B., and Calabretta, B. Phosphatidylinositol 3-kinase activity is regulated by Bcr/Abl and is required for the growth of Philadelphia chromosome-positive cells. Blood, 86: 726-736, 1995.
-
(1995)
Blood
, vol.86
, pp. 726-736
-
-
Skorski, T.1
Kanakaraj, P.2
Nieborowska-Skorska, M.3
Ratajczak, M.Z.4
Wen, S.C.5
Zon, G.6
Gerwirtz, A.M.7
Perussia, B.8
Calabretta, B.9
-
26
-
-
0033585485
-
A Bcr/Abl kinase antagonist for chronic myelogenous leukemia. a promising path for progress emerges
-
Sausville, E. A. A Bcr/Abl kinase antagonist for chronic myelogenous leukemia. A promising path for progress emerges. J. Natl. Cancer Inst., 91: 102-103, 1999.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 102-103
-
-
Sausville, E.A.1
-
27
-
-
0026746308
-
Effect of herbimycin A. an antagonist of tyrosine kinase, on Bcr/Abl oncoprotein-associated cell proliferations: Abrogative effect on the transformation of murine hematopoietic cells by transfection of a retroviral vector expressing onco-protein P210Bcr/Abl and preferential inhibition on Phi-positive leukemia cell growth
-
Okabe, M., Uehara, Y., Miyagishima, T., Itaya, T., Tanaka, M., Kuni Eda, Y., Kurosawa, M., and Miyazaki, T. Effect of herbimycin A. an antagonist of tyrosine kinase, on Bcr/Abl oncoprotein-associated cell proliferations: abrogative effect on the transformation of murine hematopoietic cells by transfection of a retroviral vector expressing onco-protein P210Bcr/Abl and preferential inhibition on Phi-positive leukemia cell growth. Blood, 80: 1330-1338, 1992.
-
(1992)
Blood
, vol.80
, pp. 1330-1338
-
-
Okabe, M.1
Uehara, Y.2
Miyagishima, T.3
Itaya, T.4
Tanaka, M.5
Kuni Eda, Y.6
Kurosawa, M.7
Miyazaki, T.8
-
28
-
-
10244255276
-
Selection of myeloid progenitors lacking Bcr/Abl mRNA in chronic myelogenous leukemia patients after in vitro treatment with the tyrosine kinase inhibitor genistein
-
Carlo-Stella, C., Dotti, G., Mangoni, E., Regazzi, E., Garau, D., Bonati, A., Almici, C., Sammarelli, G., Savoldo, B., Rizzo, M. T., and Rizzoli, V. Selection of myeloid progenitors lacking Bcr/Abl mRNA in chronic myelogenous leukemia patients after in vitro treatment with the tyrosine kinase inhibitor genistein. Blood, 88: 3091-3100, 1996.
-
(1996)
Blood
, vol.88
, pp. 3091-3100
-
-
Carlo-Stella, C.1
Dotti, G.2
Mangoni, E.3
Regazzi, E.4
Garau, D.5
Bonati, A.6
Almici, C.7
Sammarelli, G.8
Savoldo, B.9
Rizzo, M.T.10
Rizzoli, V.11
-
29
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker, B. J., Tamura, S., Buchdunger, E., Ohno, S., Segal, G. M., Fanning, S., Zimmermann, J., and Lydon, N. B. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med., 2: 561-566, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
30
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger, E., Zimmermann, J., Mett, H., Meyer, T., Müller, M., Druker, B. J., and Lydon, N. B. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res., 56: 100-104, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 100-104
-
-
Buchdunger, E.1
Zimmermann, J.2
Mett, H.3
Meyer, T.4
Müller, M.5
Druker, B.J.6
Lydon, N.B.7
-
31
-
-
0030853063
-
The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of Bcr-Abl-positive cells
-
Deininger, M. W., Goldman, J. M., Lydon, N., and Melo, J. V. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of Bcr-Abl-positive cells. Blood, 90: 3691-3698, 1997.
-
(1997)
Blood
, vol.90
, pp. 3691-3698
-
-
Deininger, M.W.1
Goldman, J.M.2
Lydon, N.3
Melo, J.V.4
-
32
-
-
0003347281
-
Phase I trial of a specific Abl tyrosine inhibitor, CGP 57148, in interferon refractory chronic myelogenous leukemia patients
-
Druker, B. J., Sawyers, C. L., Talpaz, M., Resta, D., Peng, B., and Ford, J. Phase I trial of a specific Abl tyrosine inhibitor, CGP 57148, in interferon refractory chronic myelogenous leukemia patients. Blood, 92: 252a, 1998.
-
(1998)
Blood
, vol.92
-
-
Druker, B.J.1
Sawyers, C.L.2
Talpaz, M.3
Resta, D.4
Peng, B.5
Ford, J.6
-
33
-
-
0028968949
-
Tyrosine kinase inhibition. An approach to drug development
-
Washington DC
-
Levitzki, A., and Gazit, A. Tyrosine kinase inhibition. An approach to drug development. Science (Washington DC), 267: 1782-1788, 1995.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
34
-
-
0028227405
-
Tyrphostin induced growth inhibition: Correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia
-
Kaur, G., Gazit, A., Levitzki, A., Stowe, E., Cooney, D. A., and Sausville, E. A. Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia. Anti-Cancer Drugs, 5: 213-222, 1994.
-
(1994)
Anti-Cancer Drugs
, vol.5
, pp. 213-222
-
-
Kaur, G.1
Gazit, A.2
Levitzki, A.3
Stowe, E.4
Cooney, D.A.5
Sausville, E.A.6
-
35
-
-
0032913704
-
Leukemia cell lines. in vitro models for the study of Philadelphia chromosome-positive leukemia
-
Drexler, H. G., MacLeod, R. A., and Uphoff, C. C. Leukemia cell lines. In vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res., 23: 207-215, 1999.
-
(1999)
Leuk. Res.
, vol.23
, pp. 207-215
-
-
Drexler, H.G.1
MacLeod, R.A.2
Uphoff, C.C.3
-
36
-
-
0029750057
-
Altered physical state of p21 Obcr/abl in tyrphostin AG957-treated K562 cells
-
Kaur, G., and Sausville, E. A. Altered physical state of p21 Obcr/abl in tyrphostin AG957-treated K562 cells. Anti-Cancer Drugs, 7: 815-824, 1996.
-
(1996)
Anti-Cancer Drugs
, vol.7
, pp. 815-824
-
-
Kaur, G.1
Sausville, E.A.2
-
37
-
-
0033547873
-
Protein kinase C iota activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis
-
Jamieson, L., Carpenter, L., Biden, T. J., and Fields, A. P. Protein kinase C iota activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis. J. Biol. Chem., 274: 3927-3930, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3927-3930
-
-
Jamieson, L.1
Carpenter, L.2
Biden, T.J.3
Fields, A.P.4
-
38
-
-
0031752846
-
Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores β1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors
-
Baltimore
-
Bhatia, R., Munthe, H. A., and Verfaillie, C. M. Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores β1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors. Leukemia (Baltimore), 12: 1708-1717, 1998.
-
(1998)
Leukemia
, vol.12
, pp. 1708-1717
-
-
Bhatia, R.1
Munthe, H.A.2
Verfaillie, C.M.3
-
39
-
-
0028115911
-
Antisense Bcr-Abl oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173
-
Baltimore
-
Smetsers, T. F., Skorski, T., van de Locht, L. T., Wessels, H. M., Pennings, A. H., de Witte, T., Calabretta, B., and Mensink, E. J. Antisense Bcr-Abl oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173. Leukemia (Baltimore), 8: 129-140, 1994.
-
(1994)
Leukemia
, vol.8
, pp. 129-140
-
-
Smetsers, T.F.1
Skorski, T.2
Van De Locht, L.T.3
Wessels, H.M.4
Pennings, A.H.5
De Witte, T.6
Calabretta, B.7
Mensink, E.J.8
-
40
-
-
0031409736
-
+ leukemic cells and induces apoptosis
-
+ leukemic cells and induces apoptosis. Blood Cells Mol. Dis., 23: 380-394, 1997.
-
(1997)
Blood Cells Mol. Dis.
, vol.23
, pp. 380-394
-
-
Gambacorti-Passerini, C.1
Le Coutre, P.2
Mologni, L.3
Fanelli, M.4
Bertazzoli, C.5
Marchesi, E.6
Di Nicola, M.7
Biondi, A.8
Corneo, G.M.9
Belotti, D.10
Pogliani, E.11
Lydon, N.B.12
-
41
-
-
0031869466
-
Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR-ABL tyrosine kinase. CGP 57148
-
Dan. S., Naito, M., and Tsuruo, T. Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR-ABL tyrosine kinase. CGP 57148. Cell Death Differ., 5: 710-715, 1998.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 710-715
-
-
Dan, S.1
Naito, M.2
Tsuruo, T.3
-
43
-
-
12044256844
-
Tumour induction by activated Abl involves tyrosine phosphorylation of the product of the Cbl oncogene
-
Andoniou, C. E., Thien, C. B., and Langdon, W. Y. Tumour induction by activated Abl involves tyrosine phosphorylation of the product of the Cbl oncogene. EMBO J., 13: 4515-4523, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 4515-4523
-
-
Andoniou, C.E.1
Thien, C.B.2
Langdon, W.Y.3
-
44
-
-
0029669975
-
The proto-oncogene produce p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol 3-kinase pathway
-
Sattler, M., Salgia, R., Okuda, K., Uemura, N., Durstin, M. A., Pisick, E., Xu, G., Li, J. L., Prasad, K. V., and Griffin, J. D. The proto-oncogene produce p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol 3-kinase pathway. Oncogene, 12: 839-846, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 839-846
-
-
Sattler, M.1
Salgia, R.2
Okuda, K.3
Uemura, N.4
Durstin, M.A.5
Pisick, E.6
Xu, G.7
Li, J.L.8
Prasad, K.V.9
Griffin, J.D.10
-
45
-
-
4243673307
-
Evaluation of the effect of AG957 (NSC 654705) on chronic myelogenous leukemia cells in vitro
-
Kaufmann, S. H., Svingen, P. A., Kottke, T. J., Sausville, E. A., and Tefferi. A. Evaluation of the effect of AG957 (NSC 654705) on chronic myelogenous leukemia cells in vitro. Blood, 92 (Suppl. I): 627A, 1998.
-
(1998)
Blood
, vol.92
, Issue.1 SUPPL.
-
-
Kaufmann, S.H.1
Svingen, P.A.2
Kottke, T.J.3
Sausville, E.A.4
Tefferi, A.5
-
46
-
-
0040799906
-
Characterization of caspase processing and activation of HL-60 cell cytosol under cell-free conditions: Nucleotide requirement and inhibitor profile
-
Mesner, P. W., Jr., Bible, K. C., Martins, L. M., Kottke, T. J., Srinivasula, S. M., Svingen, P. A., Chilcote, T. J., Basi, G. S., Tung, J. S., Karjewski, S., Reed, J. C., Alnemri, E. S., Earnshaw, E. C., and Kaufmann, S. H. Characterization of caspase processing and activation of HL-60 cell cytosol under cell-free conditions: nucleotide requirement and inhibitor profile. J. Biol. Chem., 274: 22635-22645, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22635-22645
-
-
Mesner P.W., Jr.1
Bible, K.C.2
Martins, L.M.3
Kottke, T.J.4
Srinivasula, S.M.5
Svingen, P.A.6
Chilcote, T.J.7
Basi, G.S.8
Tung, J.S.9
Karjewski, S.10
Reed, J.C.11
Alnemri, E.S.12
Earnshaw, E.C.13
Kaufmann, S.H.14
-
47
-
-
0014831414
-
Human bone marrow colony growth in agar-gel
-
Pike, B. L., and Robinson, W. A. Human bone marrow colony growth in agar-gel. J. Cell. Physiol., 76: 77-84, 1970.
-
(1970)
J. Cell. Physiol.
, vol.76
, pp. 77-84
-
-
Pike, B.L.1
Robinson, W.A.2
-
48
-
-
0026054953
-
Topoisomerase II levels during granulocytic maturation in vitro and in vivo
-
Kaufmann, S. H., McLaughlin, S. J., Kastan, M., Liu, L. F., Karp, J. E., and Burke, P. J. Topoisomerase II levels during granulocytic maturation in vitro and in vivo. Cancer Res., 51: 3534-3543, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 3534-3543
-
-
Kaufmann, S.H.1
McLaughlin, S.J.2
Kastan, M.3
Liu, L.F.4
Karp, J.E.5
Burke, P.J.6
-
49
-
-
0033055735
-
Comparison of paclitaxel-, 5-fluoro-2′-deoxyuridine- And epidermal growth factor-induced apoptosis: Evidence for EGF-induced anoikis
-
Kottke, T. J., Blajeski, A. L., Martins, L. M., Mesner, P. W., Jr., Davidson, N. E., Earnshaw, W. C., Armstrong, D. K., and Kaufmann, S. H. Comparison of paclitaxel-, 5-fluoro-2′-deoxyuridine- and epidermal growth factor-induced apoptosis: evidence for EGF-induced anoikis. J. Biol. Chem., 274: 15927-15936, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15927-15936
-
-
Kottke, T.J.1
Blajeski, A.L.2
Martins, L.M.3
Mesner P.W., Jr.4
Davidson, N.E.5
Earnshaw, W.C.6
Armstrong, D.K.7
Kaufmann, S.H.8
-
50
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. Measurement of protein using bicinchoninic acid. Anal. Biochem., 150: 76-85, 1985.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
51
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell, 1: 949-957, 1998.
-
(1998)
Mol. Cell
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
52
-
-
0032518446
-
Dominant-negative FADD inhibits TNFR60-, Fas/Apol-, and TRAIL-R/Apo2-mediated cell death but not gene induction
-
Wajant, H., Johannes, F. J., Haas, E., Siemienski, K., Schwenzer, R., Schubert, G., Weiss, T., Grell. M., and Scheurich, P. Dominant-negative FADD inhibits TNFR60-, Fas/Apol-, and TRAIL-R/Apo2-mediated cell death but not gene induction. Curr. Biol., 8: 113-116, 1998.
-
(1998)
Curr. Biol.
, vol.8
, pp. 113-116
-
-
Wajant, H.1
Johannes, F.J.2
Haas, E.3
Siemienski, K.4
Schwenzer, R.5
Schubert, G.6
Weiss, T.7
Grell, M.8
Scheurich, P.9
-
53
-
-
0028144249
-
Topoisomerase II levels and drug sensitivity in adult acute myelogenous leukemia
-
Kaufmann, S. H., Karp, J. E., Jones, R. J., Miller, C. B., Schneider, E., Zwelling, L. A., Cowan, K., Wendel, K., and Burke, P. J. Topoisomerase II levels and drug sensitivity in adult acute myelogenous leukemia. Blood, 83: 517-530, 1994.
-
(1994)
Blood
, vol.83
, pp. 517-530
-
-
Kaufmann, S.H.1
Karp, J.E.2
Jones, R.J.3
Miller, C.B.4
Schneider, E.5
Zwelling, L.A.6
Cowan, K.7
Wendel, K.8
Burke, P.J.9
-
54
-
-
0004252445
-
-
Englewood Cliffs, NJ: Prentice-Hall, Inc.
-
Zar, J. H. Biostatistical Analysis. Englewood Cliffs, NJ: Prentice-Hall, Inc., 1974.
-
(1974)
Biostatistical Analysis
-
-
Zar, J.H.1
-
55
-
-
0028084328
-
The COOH terminus of c-Abl tyrosine kinase contains distinct F- And G-actin binding domains with bundling activity
-
Van Etten, R. A., Jackson, P. K., Baltimore, D., Sanders, M. C., Matsudaira, P. T., and Janmey, P. A. The COOH terminus of c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. J. Cell Biol., 124: 325-340, 1994.
-
(1994)
J. Cell Biol.
, vol.124
, pp. 325-340
-
-
Van Etten, R.A.1
Jackson, P.K.2
Baltimore, D.3
Sanders, M.C.4
Matsudaira, P.T.5
Janmey, P.A.6
-
56
-
-
0029845079
-
P210BCR/ABL, p190BCR/ABL. and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines
-
Okuda, K., Golub, T. R., Gilliland, D. G., and Griffin, J. D. p210BCR/ABL, p190BCR/ABL. and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines. Oncogene, 13: 1147-1152, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 1147-1152
-
-
Okuda, K.1
Golub, T.R.2
Gilliland, D.G.3
Griffin, J.D.4
-
57
-
-
0027255417
-
Specific proteolytic fragmentation of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. Specific proteolytic fragmentation of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res., 53: 3976-3985, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
58
-
-
0032885388
-
Mammalian caspases. Structure, activation, substrates, and functions during apoptosis
-
Earnshaw, W. C., Martins, L. M., and Kaufmann, S. H. Mammalian caspases. Structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem., 68: 383-424, 1999.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
59
-
-
0032575752
-
Mitochondria and apoptosis
-
Washington DC
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Washington DC), 281: 1309-1312, 1998.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
60
-
-
0032532653
-
Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- Or etoposide-treated HL-60 cells
-
Perkins, C., Kim, C. N., Fang, G., and Bhalla, K. N. Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells. Cancer Res., 58: 4561-4566, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4561-4566
-
-
Perkins, C.1
Kim, C.N.2
Fang, G.3
Bhalla, K.N.4
-
61
-
-
0033582526
-
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
-
Sun, X. M., MacFarlane, M., Zhuang, J., Wolf, B. B., Green, D. R., and Cohen, G. M. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem., 274: 5053-5060, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5053-5060
-
-
Sun, X.M.1
MacFarlane, M.2
Zhuang, J.3
Wolf, B.B.4
Green, D.R.5
Cohen, G.M.6
-
62
-
-
0029935682
-
Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen, C., Herr, I., Krammer, P. H., and Debatin, K-M. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat. Med., 2: 574-577, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.-M.4
-
63
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
-
Muller, M., Strand, S., Hug, H., Heinemann, E. M., Walczak, H., Hofmann, W. J., Stremmel, W., Krammer, P. H., and Galle, P. R. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J. Clin. Investig., 99: 403-413, 1997.
-
(1997)
J. Clin. Investig.
, vol.99
, pp. 403-413
-
-
Muller, M.1
Strand, S.2
Hug, H.3
Heinemann, E.M.4
Walczak, H.5
Hofmann, W.J.6
Stremmel, W.7
Krammer, P.H.8
Galle, P.R.9
-
64
-
-
0030752603
-
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells
-
Fulda, S., Sieverts, H., Friesen, C., Herr, I., and Debatin, K. M. The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res., 57: 3823-3829, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3823-3829
-
-
Fulda, S.1
Sieverts, H.2
Friesen, C.3
Herr, I.4
Debatin, K.M.5
-
65
-
-
0031966318
-
Chemosensilivity of solid tumor cells in vitro is related to activation of the CD95 system
-
Fulda, S., Los, M., Friesen, C., and Debatin, K. M. Chemosensilivity of solid tumor cells in vitro is related to activation of the CD95 system. Int. J. Cancer, 76: 105-114, 1998.
-
(1998)
Int. J. Cancer
, vol.76
, pp. 105-114
-
-
Fulda, S.1
Los, M.2
Friesen, C.3
Debatin, K.M.4
-
66
-
-
0033044686
-
A fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells
-
Tillman, D. M., Petak, I., and Houghton, J. A. A fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells. Clin. Cancer Res., 5: 425-430, 1999.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 425-430
-
-
Tillman, D.M.1
Petak, I.2
Houghton, J.A.3
-
67
-
-
0030892234
-
Apoptosis by death factor
-
Nagata, S. Apoptosis by death factor. Cell, 88: 355-365, 1997.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
68
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Washington DC
-
Ashkenazi, A., and Dixit, V. M. Death receptors: signaling and modulation. Science (Washington DC). 281: 1305-1308, 1998.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
69
-
-
0032143986
-
Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apol, and DR3 and is lethal prenatally
-
Varfolomeev, E. E., Schuchmann, M., Luria, V., Chiannilkulchai, N., Beckmann, J. S., Mett, I. L., Rebrikov, D., Brodianski, V. M., Kemper, O. C., Kollet, O., Lapidot, T., Soffer, D., Sobe, T., Avraham, K. B., Goncharov, T., Holtmann, H., Lonai, P., and Wallach, D. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apol, and DR3 and is lethal prenatally. Immunity, 9: 267-276, 1998.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
Lapidot, T.11
Soffer, D.12
Sobe, T.13
Avraham, K.B.14
Goncharov, T.15
Holtmann, H.16
Lonai, P.17
Wallach, D.18
-
70
-
-
7144263731
-
FADD. Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Washington DC
-
Yeh, W-C., de la Pompa, J. L., McCurrach, M. E., Shu, H-B., Elia, A. J., Shahinian, A., Ng, M., Wakeham, A., Khoo, W., Mitchell, K., El-Deiry, W. S., Lowe, S. W., Goeddel, D. V., and Mak, T. W. FADD. Essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science (Washington DC), 279: 1954-1958, 1998.
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.-C.1
De La Pompa, J.L.2
McCurrach, M.E.3
Shu, H.-B.4
Elia, A.J.5
Shahinian, A.6
Ng, M.7
Wakeham, A.8
Khoo, W.9
Mitchell, K.10
El-Deiry, W.S.11
Lowe, S.W.12
Goeddel, D.V.13
Mak, T.W.14
-
71
-
-
0028596203
-
Involvement of apoptosis antigen fas in clonal deletion of human thymocytes
-
Yonehara, S., Nishimura, Y., Kishil, S., Yonehara, M., Takazawa, K., Tamatani, T., and Ishii, A. Involvement of apoptosis antigen fas in clonal deletion of human thymocytes. Int. Immunol., 6: 1849-1856, 1994.
-
(1994)
Int. Immunol.
, vol.6
, pp. 1849-1856
-
-
Yonehara, S.1
Nishimura, Y.2
Kishil, S.3
Yonehara, M.4
Takazawa, K.5
Tamatani, T.6
Ishii, A.7
-
72
-
-
0030806351
-
Comparison of apoptosis in wild-type and fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on fas/fas ligand interactions
-
Eischen, C. M., Kottke, T. J., Martins, L. M., Basi, G. S., Tung, J. S., Earnshaw, W. C., Leibson, P. J., and Kaufmann, S. H. Comparison of apoptosis in wild-type and fas-resistant cells: chemotherapy-induced apoptosis is not dependent on fas/fas ligand interactions. Blood, 90: 935-943, 1997.
-
(1997)
Blood
, vol.90
, pp. 935-943
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
Basi, G.S.4
Tung, J.S.5
Earnshaw, W.C.6
Leibson, P.J.7
Kaufmann, S.H.8
-
73
-
-
0031427452
-
The fas signaling pathway is functional in colon carcinoma cells and induces apoptosis
-
Houghton, J. A., Harwood, F. G., Gibson, A. A., and Tillman, D. M. The fas signaling pathway is functional in colon carcinoma cells and induces apoptosis. Clin. Cancer Res., 3: 2205-2209, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 2205-2209
-
-
Houghton, J.A.1
Harwood, F.G.2
Gibson, A.A.3
Tillman, D.M.4
-
74
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
-
Chaudhary, P. M., Eby, M., Jasmin, A., Bookwalter, A., Murray, J., and Hood, L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity, 7: 821-830, 1997.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
75
-
-
14344254868
-
Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice
-
Liu, M., Bryant, M. S., Chen, J., Lee, S., Yaremko, B., Lipari, P., Malkowski, M., Ferrari, E., Nielsen, L., Prioli, N., Dell, J., Sinha, D., Syed, J., Korfmacher, W. A., Nomeir, A. A., Lin, C. C., Wang, L., Taveras, A. G., Doll, R. J., Njoroge, F. G., Mallams, A. K., Remis-zewski, S., Catino, J. J., Girijavallabhan, V. M., and Bishop, W. R. Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice. Cancer Res., 58: 4947-4956, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4947-4956
-
-
Liu, M.1
Bryant, M.S.2
Chen, J.3
Lee, S.4
Yaremko, B.5
Lipari, P.6
Malkowski, M.7
Ferrari, E.8
Nielsen, L.9
Prioli, N.10
Dell, J.11
Sinha, D.12
Syed, J.13
Korfmacher, W.A.14
Nomeir, A.A.15
Lin, C.C.16
Wang, L.17
Taveras, A.G.18
Doll, R.J.19
Njoroge, F.G.20
Mallams, A.K.21
Remis-zewski, S.22
Catino, J.J.23
Girijavallabhan, V.M.24
Bishop, W.R.25
more..
-
76
-
-
0027374488
-
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
-
Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y., and Matsuda, Y. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem., 268: 25846-25856, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 25846-25856
-
-
Yano, H.1
Nakanishi, S.2
Kimura, K.3
Hanai, N.4
Saitoh, Y.5
Fukui, Y.6
Nonomura, Y.7
Matsuda, Y.8
-
77
-
-
0028217223
-
Wortmannin, a potent and selective inhibitor of phosphatidylinositol3-kinase
-
Powis, G., Bonjoulkian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., and Grindey, G. Wortmannin, a potent and selective inhibitor of phosphatidylinositol3-kinase. Cancer Res., 54: 2419-2423, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 2419-2423
-
-
Powis, G.1
Bonjoulkian, R.2
Berggren, M.M.3
Gallegos, A.4
Abraham, R.5
Ashendel, C.6
Zalkow, L.7
Matter, W.F.8
Dodge, J.9
Grindey, G.10
-
78
-
-
0029034774
-
Inhibition of MAP kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
-
Pang, L., Sawada, T., Decker, S. J., and Saltiel, A. R. Inhibition of MAP kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem., 270: 13585-13588, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13585-13588
-
-
Pang, L.1
Sawada, T.2
Decker, S.J.3
Saltiel, A.R.4
-
79
-
-
0024458557
-
Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition
-
Chang, M. P., Bramhall, J., Graves, S., Bonavida, B., and Wisnieski, B. J. Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition. J. Biol. Chem., 264: 15261-15267, 1989.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 15261-15267
-
-
Chang, M.P.1
Bramhall, J.2
Graves, S.3
Bonavida, B.4
Wisnieski, B.J.5
-
80
-
-
0031882339
-
6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin
-
Budihardjo, I. I., Walker, D. L., Svingen, P. A., Buckwalter, C. A., Desnoyers. S., Eckdahl, S., Shah, G. M., Poirier, G. G., Reid. J. M., Ames, M. M., and Kaufmann, S. H. 6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin. Clin. Cancer Res., 4: 117-130, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 117-130
-
-
Budihardjo, I.I.1
Walker, D.L.2
Svingen, P.A.3
Buckwalter, C.A.4
Desnoyers, S.5
Eckdahl, S.6
Shah, G.M.7
Poirier, G.G.8
Reid, J.M.9
Ames, M.M.10
Kaufmann, S.H.11
-
81
-
-
0029067452
-
In vitro cultivation of tumor cells in hollow fibers
-
Hollingshead, M. G., Alley, M. C., Camalier, R. F., Abbott, B. .1., Mayo, J. G., Malspeis, L., and Grever. A. L. In vitro cultivation of tumor cells in hollow fibers. Life Sci., 57: 131-141, 1995.
-
(1995)
Life Sci.
, vol.57
, pp. 131-141
-
-
Hollingshead, M.G.1
Alley, M.C.2
Camalier, R.F.3
Abbott B. I4
Mayo, J.G.5
Malspeis, L.6
Grever, A.L.7
-
82
-
-
0033152362
-
+ chronic myelogenous leukemia progenitor cells
-
+ chronic myelogenous leukemia progenitor cells. Blood, 93: 3973-3982, 1999.
-
(1999)
Blood
, vol.93
, pp. 3973-3982
-
-
Carlo-Stella, C.1
Regazzi, E.2
Sammarelli, G.3
Colla, S.4
Garau, D.5
Gazit, A.6
Savoldo, B.7
Cilloni, D.8
Tabilio, A.9
Levitzki, A.10
Rizzoli, V.11
-
83
-
-
0030584729
-
Treatment of chronic myelogenous leukemia: Current status and investigational options
-
Kantarjian, H. M., O'Brien, S., Anderlini, P., and Talpaz, M. Treatment of chronic myelogenous leukemia: current status and investigational options. Blood, 87: 3069-3081, 1996.
-
(1996)
Blood
, vol.87
, pp. 3069-3081
-
-
Kantarjian, H.M.1
O'Brien, S.2
Anderlini, P.3
Talpaz, M.4
-
84
-
-
0030884436
-
Biology and treatment of chronic myelogenous leukemia
-
Enright, H., and McGlave, P. B. Biology and treatment of chronic myelogenous leukemia. Oncology, 11: 295-1300, 1997.
-
(1997)
Oncology
, vol.11
, pp. 295-1300
-
-
Enright, H.1
McGlave, P.B.2
-
85
-
-
0030902062
-
Autologous transplantation therapy for chronic myelogenous leukemia
-
Bhatia, R., Verfaillie, C. M., Miller, J. S., and McGlave, P. H. Autologous transplantation therapy for chronic myelogenous leukemia. Blood, 89: 2623-2634, 1997.
-
(1997)
Blood
, vol.89
, pp. 2623-2634
-
-
Bhatia, R.1
Verfaillie, C.M.2
Miller, J.S.3
McGlave, P.H.4
-
86
-
-
85041132416
-
Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML
-
Deisseroth, A. B., Zu, Z., Claxton, D., Hanania, E. G., Fu, S., Ellerson, D., Goldberg, L., Thomas, M., Janicek, K., Anderson, W. F., Hester, J., Korbling, M., Durett, A., Moen, R., Berenson, R., Heimfeld, S., Hamer, J., Calvert, L., Tibbits, P., Talpaz, M., Kantarjian, H., Champlin, R., and Reading, C. Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood, 83: 3068-3076, 1994.
-
(1994)
Blood
, vol.83
, pp. 3068-3076
-
-
Deisseroth, A.B.1
Zu, Z.2
Claxton, D.3
Hanania, E.G.4
Fu, S.5
Ellerson, D.6
Goldberg, L.7
Thomas, M.8
Janicek, K.9
Anderson, W.F.10
Hester, J.11
Korbling, M.12
Durett, A.13
Moen, R.14
Berenson, R.15
Heimfeld, S.16
Hamer, J.17
Calvert, L.18
Tibbits, P.19
Talpaz, M.20
Kantarjian, H.21
Champlin, R.22
Reading, C.23
more..
-
87
-
-
0032170989
-
Comparative analysis of autografting in chronic myelogenous leukemia: Effects of priming regimen and marrow or blood origin of stem cells
-
Verfaillie, C. M., Bhatia, R., Steinbuch, M., DeFor, T., Hirsch, B., Miller, J. S., Weisdorf, D., and McGlave, P. B. Comparative analysis of autografting in chronic myelogenous leukemia: effects of priming regimen and marrow or blood origin of stem cells. Blood, 92: 1820-1831, 1998.
-
(1998)
Blood
, vol.92
, pp. 1820-1831
-
-
Verfaillie, C.M.1
Bhatia, R.2
Steinbuch, M.3
DeFor, T.4
Hirsch, B.5
Miller, J.S.6
Weisdorf, D.7
McGlave, P.B.8
-
88
-
-
15644384377
-
Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution
-
Samajima, K., Tone, S., Kottke, T. J., Enari, M., Sakahira, H., Cooke, C. A., Durrein, F., Martins, L. M., Nagata, S., Kaufmann, S. H., and Earnshaw, W. F. Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution. J. Cell Biol., 143: 225-239, 1998.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 225-239
-
-
Samajima, K.1
Tone, S.2
Kottke, T.J.3
Enari, M.4
Sakahira, H.5
Cooke, C.A.6
Durrein, F.7
Martins, L.M.8
Nagata, S.9
Kaufmann, S.H.10
Earnshaw, W.F.11
-
89
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria, J. N., Tibbetts, R. S., Busby, E. C., Kennedy, A. P., Hill, D. E., and Abraham, R. T. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res., 58: 4375-4382, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Tibbetts, R.S.2
Busby, E.C.3
Kennedy, A.P.4
Hill, D.E.5
Abraham, R.T.6
-
90
-
-
0033548484
-
A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-raf and a-raf
-
Sutor, S. L., Vroman, B. T., Armstrong, E. A., Abraham, R. T., and Karnitz, L. M. A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-raf and a-raf. J. Biol. Chem., 274: 7002-7010, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7002-7010
-
-
Sutor, S.L.1
Vroman, B.T.2
Armstrong, E.A.3
Abraham, R.T.4
Karnitz, L.M.5
-
91
-
-
0027163397
-
The biology of normal and neoplastic stem cells in CML
-
Eaves, C., Udomsakdi, C., Cashman, J., Barnett, M., and Eaves, A. The biology of normal and neoplastic stem cells in CML. Leuk. Lymphoma, 11: 245-253, 1993.
-
(1993)
Leuk. Lymphoma
, vol.11
, pp. 245-253
-
-
Eaves, C.1
Udomsakdi, C.2
Cashman, J.3
Barnett, M.4
Eaves, A.5
|