Serum-starvation-induced changes in protein synthesis and morphology of Borrelia burgdorferi

Microbiology

Volumn 146, Issue 1, 2000, Pages 119-127

  Alban, P Scott ^a   Johnson, Paul W ^a   Nelson, David R ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Borrelia burgdorferi; Cysts; Lyme disease; Serum starvation; Spirochaete

Indexed keywords

BACTERIAL PROTEIN; TETRACYCLINE;

ARTICLE; BACTERIAL INFECTION; BACTERIUM CULTURE; BORRELIA BURGDORFERI; CELL LABELING; CELL SHAPE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; FLUOROGRAPHY; HUMAN; MONKEY; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

BACTERIA (MICROORGANISMS); BORRELIA; BORRELIA BURGDORFERI; ORYCTOLAGUS CUNICULUS; SPIROCHAETA;

EID: 0033969719     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-146-1-119     Document Type: Article

References (43)

1. Aberer, E., Koszik, F. & Silberer, M. (1997). Why is chronic Lyme borreliosis chronic? Clin Infect Dis 25 (Suppl 1), S64-S70.
2. Akins, D. R., Bourell, K. W., Caimano, M. J., Norgard, M. V. & Radolf, J. D. (1998). A new animal model for studying Lyme disease spirochetes in a mammalian host adapted state. J Clin Invest 101, 2240-2250.
3. American Public Health Association (1975). Standard Methods for the Examination of Water and Wastewater, 14th edn, pp. 923-927. New York: American Public Health Association.
4. Barbour, A. G. (1984). Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med 57, 521-525.
5. Barbour, A. & Hayes, S. F. (1986). Biology of Borrelia species. Microbiol Rev 50, 381-400.
6. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254.
7. Brorson, O. & Brorson, S. H. (1997). Transformation of cystic forms of Borrelia burgdorferi to normal, motile spirochetes. Infection 25, 240-245.
8. Brorson, O. & Brorson, S. H. (1998a). In vitro conversion of Borrelia burgdorferi to cystic forms in spinal fluid, and transformation to mobile spirochetes by incubation in BSK-H media. Infection 26, 144-150.
9. Brorson, O. & Brorson, S. H. (1998b). A rapid method for generation of cystic forms of Borrelia burgdorferi, and their reversal to mobile spirochetes. APMIS 106, 1131-1141.
10. Burgdorfer, W. & Hayes, S. F. (1989). Vector-spirochete relationship in louse-borne and tickborne borreliosis with emphasis on Lyme disease. In Advances of Disease Vector Research, pp. 127-150. Edited by K. F. Harris. New York: Springer.
11. Burgdorfer, W., Barbour, A. G., Hayes, S. F., Benach, J. L., Grunwaldt, E. & Davis, J. P. (1982). Lyme disease, a tick-borne spirochetosis? Science 216, 1317-1319.
12. Carreiro, M. M., Laux, D. C. & Nelson, D. R. (1990). Characterization of the heat shock response and identification of heat shock antigens of B. burgdorferi. Infect Immun 58, 2186-2191.
13. Cashel, M. & Rudd, K. E. (1987). The stringent response. In Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, pp. 1410-1438. Edited by F. C. Neidhardt and others. Washington, DC: American Society for Microbiology.
14. Das, S., Barthold, S. W., Giles, S. S., Montgomery, R. R., Telford, S. R., III & Fikrig, E. (1997). Temporal pattern of Borrelia burgdorferi p21 expression in ticks and mammalian hosts. J Clin Invest 99, 987-995.
15. Fikrig, E., Feng, W., Aversa, J., Schoen, R. T. & Flavell, R. A. (1998). Differential expression of Borrelia burgdorferi genes during erythema migrans and Lyme arthritis. J Infect Dis 178, 1198-1201.
16. Fraser, C. M., Casjens, S., Huang, W. M. & 35 other authors (1997). Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390, 580-586.
17. Garcia, T., Otto, K., Kjelleberg, S. & Nelson, D. R. (1997). Growth of Vibrio anguillarum in salmon intestinal mucus. Appl Environ Microbiol 63, 1034-1039.
18. Garon, C. F., Dorward, D. W. & Corwin, M. D. (1989). Structural features of Borrelia burgdorferi - the Lyme disease spirochete: silver staining for nucleic acids. Scanning Microsc (Suppl 3), 109-115.
19. Girouard, L., Laux, D. C., Jindal, S. & Nelson, D. R. (1993). Immune recognition of human Hsp60 by Lyme disease patient sera. Microb Pathog 14, 287-297.
20. Hulinska, D., Bartak, P., Hercogova, J., Hancil, J., Basta, J. & Schramlova, J. (1994). Electron microscopy of Langerhans cells and Borrelia burgdorferi in Lyme disease patients. Zentbl Bakteriol 280, 348-359.
21. Johnson, R. C. & Norton Hughes, C. A. (1992). The Genus Borrelia. In The Prokaryotes: a Handbook on Habitats, Isolation and Identification of Bacteria, pp. 3560-3566. Edited by M. P. Starr, H. Stolp, A. Trüper & H. G. Balows. New York: Springer.
22. Kaiser, D. (1984). Regulation of multicellular development in Myxobacteria. In Microbial Development, pp. 197-218. Edited by R. Losick & L. Shapiro. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
23. Kersten, A., Poitscheck, S., Rauch, S. & Aberer, E. (1995). Effects of penicillin, ceftriaxone, and doxycycline on morphology of Borrelia burgdorferi. Antimicrob Agents Chemother 39, 1127-1133.
24. Kjelleberg, S., Hermansson, P., Marden, P. & Jones, G. W. (1987). The transient phase between growth and nongrowth of heterotrophic bacteria, with emphasis on the marine environment. Annu Rev Microbiol 41, 25-49.
25. Laemmli, U. K. (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Mature 227, 680-685.
26. Losick, R. & Youngman, P. (1984). Endospore formation in Bacillus. In Microbial Development, pp. 63-88. Edited by R. Losick & L. Shapiro. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
27. Nyström, T. (1993). Global systems approach to the physiology of the starved cell. In Starvation in Bacteria, pp. 129-150. Edited by S. Kjelleberg. New York: Plenum.
28. Nyström, T. & Kjelleberg, S. (1989). Role of protein synthesis in the cell division and starvation-induced resistance to autolysis of a marine Vibrio during the initial phases of starvation. J Gen Microbiol 135, 1599-1606.
29. Ostling, J., Holmquist, L. & Kjelleberg, S. (1996). Global analysis of the carbon starvation response of a marine Vibrio species with disruptions in genes homologous to relA and spoT. J Bacterial 178, 4901-4908.
30. Philipp, M. T., Aydintug, M. K., Bohm, R. P. & 7 other authors (1993). Early and early disseminated phases of Lyme disease in the rhesus monkey: a model for infection in humans. Infect Immun 61, 3047-3059.
31. Preac Mursic, V., Weber, K., Pfister, H. W., Wilske, B., Gross, B., Baumann, A. & Prokop, J. (1989). Formation and cultivation of Borrelia burgdorferi spheroplast L-form variants. Infection 17, 355-359.
32. Roberts, E. D., Bohm, R. P., Lowrie, R. C., Habicht G., Katona, L., Piesman, J. & Philipp, M. (1998). Pathogenesis of Lyme neuroborreliosis in the rhesus monkey: the early disseminated and chronic phases of disease in the peripheral nervous system. J Infect Dis 178, 722-732.
33. Schwan, T. G., Piesman, J., Golde, W. T., Dolan, M. C. & Rosa, P. A. (1995). Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc Natl Acad Sci USA 92, 2909-2913.
34. Scorpio, A., Johnson, P., Laquerre, A. & Nelson, D. R. (1994). Subcellular localization and chaperone functions of Hsp60 and Hsp70 in Borrelia burgdorferi. J Bacteriol 176, 6449-6456.
35. Seyfzadeh, M., Keener, J. & Nomura, M. (1993). spoT-dependent accumulation of guanosine tetraphosphate in response to fatty acid starvation in Escherichia coli. Proc Natl Acad Sci USA 90, 11004-11008.
36. Siegele, D. A. & Kolter, R. (1992). Life after log. J Bacteriol 174, 345-348.
37. de Silva, A. M. & Fikrig, E. (1997). Arthropod and host-specific gene expression by Borrelia burgdorferi. J Clin Invest 99, 377-379.
38. de Silva, A. M., Telford, S. R., Brunet, L. R., Barthold, S. W. & Fikrig, E. (1996). Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J Exp Med 183, 271-275.
39. Steere, A. C. (1989). Lyme disease. N Engl J Med 321, 586-596.
40. Suk, K., Das, S., Sun, W., Jwang, B., Barthold, S. W., Flavell, R. A. & Fikrig, E. (1995). Borrelia burgdorferi genes selectively expressed in the infected host. Proc Natl Acad Sci USA 92, 4269-4273.
41. Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76, 4350-4354.
42. Williams, K. R., Samandar, S. M., Stone, K. L., Saylor, M. & Rush, J. (1996). Matrix assisted-laser desorption ionization mass spectrometry as a complement to internal protein sequencing. In The Protein Protocols Handbook, pp. 541-555. Edited by J. M. Walker. Totowa: Humana Press.
43. Zhang, J.-R., Hardham, J. M., Barbour, A. G. & Norris, S. J. (1997). Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89, 275-285.