메뉴 건너뛰기




Volumn 32, Issue 2, 2000, Pages 307-316

Persistence of viral replication after anti-HBe seroconversion during antiviral therapy for chronic hepatitis B

Author keywords

Antiviral therpay; Hepatitis B virus; Immune response; Pre core mutants; Viral resistance

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; FAMCICLOVIR; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; VIRUS DNA;

EID: 0033967714     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(00)80077-X     Document Type: Article
Times cited : (59)

References (41)
  • 1
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Lee WM. Hepatitis B virus infection. N Engl J Med. 337:1997;1733-1745.
    • (1997) N Engl J Med , vol.337 , pp. 1733-1745
    • Lee, W.M.1
  • 2
    • 0023184948 scopus 로고
    • Chronic type B hepatitis and the healthy HBs Ag carrier state
    • Hoofnagle JH, Shafritz DA, Popper H. Chronic type B hepatitis and the healthy HBs Ag carrier state. Hepatology. 7:1987;758-763.
    • (1987) Hepatology , vol.7 , pp. 758-763
    • Hoofnagle, J.H.1    Shafritz, D.A.2    Popper, H.3
  • 3
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle JH, Di Bisceglie AM. The treatment of chronic viral hepatitis. N Engl J Med. 336:1997;347-356.
    • (1997) N Engl J Med , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1    Di Bisceglie, A.M.2
  • 5
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman W, Hadziyannis S, Mc Garvey MJ, Jacyna M, Karayiannis P, Makris A, et al. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet. ii:1989;588-591.
    • (1989) Lancet , vol.2 , pp. 588-591
    • Carman, W.1    Hadziyannis, S.2    Mc Garvey, M.J.3    Jacyna, M.4    Karayiannis, P.5    Makris, A.6
  • 6
    • 0025236260 scopus 로고
    • Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen
    • Okamoto H, Yotsumoto S, Akahane Y, Yamanaka T, Miyazaki Y, Sugai Y, et al. Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen. J Virol. 64:1990;1298-1303.
    • (1990) J Virol , vol.64 , pp. 1298-1303
    • Okamoto, H.1    Yotsumoto, S.2    Akahane, Y.3    Yamanaka, T.4    Miyazaki, Y.5    Sugai, Y.6
  • 7
    • 0025360675 scopus 로고
    • Active hepatitis B virus replication in the presence of anti-HBe is associated with viral variants containing an inactive pre-C region
    • Tong S, Li J, Vivitski L, Trépo C. Active hepatitis B virus replication in the presence of anti-HBe is associated with viral variants containing an inactive pre-C region. Virology. 176:1990;596-603.
    • (1990) Virology , vol.176 , pp. 596-603
    • Tong, S.1    Li, J.2    Vivitski, L.3    Trépo, C.4
  • 8
    • 0028222146 scopus 로고
    • Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pregenome encapsidation signal
    • Lok A, Akarca U, Greene S. Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pregenome encapsidation signal. Proc Natl Acad Sci USA. 91:1994;4077-4081.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4077-4081
    • Lok, A.1    Akarca, U.2    Greene, S.3
  • 9
    • 0029817029 scopus 로고    scopus 로고
    • Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication
    • Buckwold VE, Xu Z, Chen M, Yen TSB, Ou J-H. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol. 70:1996;5845-5851.
    • (1996) J Virol , vol.70 , pp. 5845-5851
    • Buckwold, V.E.1    Xu, Z.2    Chen, M.3    Yen, T.S.B.4    Ou, J.-H.5
  • 10
    • 0027992963 scopus 로고
    • Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen
    • Okamoto H, Tsuda F, Akahane Y, Sugai Y, Yoshiba M, Moriyama K, et al. Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol. 68:1994;8102-8110.
    • (1994) J Virol , vol.68 , pp. 8102-8110
    • Okamoto, H.1    Tsuda, F.2    Akahane, Y.3    Sugai, Y.4    Yoshiba, M.5    Moriyama, K.6
  • 11
    • 0029914072 scopus 로고    scopus 로고
    • Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease
    • Günther S, Piwon N, Iwanska A, Schilling R, Meisel H, Will H. Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease. J Virol. 70:1996;8318-8331.
    • (1996) J Virol , vol.70 , pp. 8318-8331
    • Günther, S.1    Piwon, N.2    Iwanska, A.3    Schilling, R.4    Meisel, H.5    Will, H.6
  • 12
    • 17544403729 scopus 로고    scopus 로고
    • Analysis of hepatitis B virus populations in an interferon-alpha-treated patient reveals predominant mutations in the C-gene and changing e-antigenicity
    • Günther S, Paulij W, Meisel H, Will H. Analysis of hepatitis B virus populations in an interferon-alpha-treated patient reveals predominant mutations in the C-gene and changing e-antigenicity. Virology. 244:1998;146-160.
    • (1998) Virology , vol.244 , pp. 146-160
    • Günther, S.1    Paulij, W.2    Meisel, H.3    Will, H.4
  • 15
    • 0030004556 scopus 로고    scopus 로고
    • Analysis of hepatitis B virus genotypes and pre-core region variability during interferon treatment of HBe antigen negative chronic hepatitis B
    • Zhang X, Zoulim F, Habersetzer F, Xiong S, Trépo C. Analysis of hepatitis B virus genotypes and pre-core region variability during interferon treatment of HBe antigen negative chronic hepatitis B. J Med Virol. 48:1996;8-16.
    • (1996) J Med Virol , vol.48 , pp. 8-16
    • Zhang, X.1    Zoulim, F.2    Habersetzer, F.3    Xiong, S.4    Trépo, C.5
  • 16
    • 0028888409 scopus 로고
    • Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance
    • Lok ASF, Akarca US, Greene S. Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance. Hepatology. 21:1995;19-24.
    • (1995) Hepatology , vol.21 , pp. 19-24
    • Lok, A.S.F.1    Akarca, U.S.2    Greene, S.3
  • 17
    • 0032979682 scopus 로고    scopus 로고
    • Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion
    • Chan HL, Hussain M, Lok AS. Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion. Hepatology. 29:1999;976-984.
    • (1999) Hepatology , vol.29 , pp. 976-984
    • Chan, H.L.1    Hussain, M.2    Lok, A.S.3
  • 20
    • 0032125193 scopus 로고    scopus 로고
    • Drug therapy for chronic hepatitis B: Antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy
    • Zoulim F, Trépo C. Drug therapy for chronic hepatitis B: antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy. J Hepatol. 29:1998;151-168.
    • (1998) J Hepatol , vol.29 , pp. 151-168
    • Zoulim, F.1    Trépo, C.2
  • 22
    • 0030905343 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation
    • Aye TT, Bartholomeusz A, Shaw T, Bowden S, Breschkin A, McMillan J, et al. Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation. J Hepatol. 1997;1148-1153.
    • (1997) J Hepatol , pp. 1148-1153
    • Aye, T.T.1    Bartholomeusz, A.2    Shaw, T.3    Bowden, S.4    Breschkin, A.5    McMillan, J.6
  • 23
    • 0000987382 scopus 로고    scopus 로고
    • The emergence of famciclovir resistant mutations in the hepatitis B virus polymerase during therapy following liver transplantation
    • abstract 958
    • Locarnini SA, Aye TT, Shaw T, De Man R, Angus PW, McCaughan GW, et al. The emergence of famciclovir resistant mutations in the hepatitis B virus polymerase during therapy following liver transplantation. Hepatology. 26:((N04 Pt2)):1997;. abstract 958.
    • (1997) Hepatology , vol.26 , Issue.N04 PT2
    • Locarnini, S.A.1    Aye, T.T.2    Shaw, T.3    De Man, R.4    Angus, P.W.5    McCaughan, G.W.6
  • 24
    • 0032173354 scopus 로고    scopus 로고
    • The sequential occurrence of viral mutations in a liver transplant recipient re-infected with hepatitis B: Hepatitis B immune globulin escape, famciclovir non-response, followed by lamivudine resistance resulting in graft loss
    • de Man RA, Bartholomeusz AI, Niesters HGM, Zondervan PE, Locarnini SA. The sequential occurrence of viral mutations in a liver transplant recipient re-infected with hepatitis B: hepatitis B immune globulin escape, famciclovir non-response, followed by lamivudine resistance resulting in graft loss. J Hepatol. 29:1998;669-675.
    • (1998) J Hepatol , vol.29 , pp. 669-675
    • De Man, R.A.1    Bartholomeusz, A.I.2    Niesters, H.G.M.3    Zondervan, P.E.4    Locarnini, S.A.5
  • 25
    • 0031739868 scopus 로고    scopus 로고
    • Clinical evaluation of the branched DNA assay for hepatitis B virus DNA detection in patients with chronic hepatitis B lacking hepatitis B e antigen and treated with interferon alpha
    • Habersetzer F, Zoulim F, Jusot JF, Zhang X, Trabaud MA, Chevallier P, et al. Clinical evaluation of the branched DNA assay for hepatitis B virus DNA detection in patients with chronic hepatitis B lacking hepatitis B e antigen and treated with interferon alpha. J Viral Hepatitis. 5:1998;407-414.
    • (1998) J Viral Hepatitis , vol.5 , pp. 407-414
    • Habersetzer, F.1    Zoulim, F.2    Jusot, J.F.3    Zhang, X.4    Trabaud, M.A.5    Chevallier, P.6
  • 28
    • 0032193013 scopus 로고    scopus 로고
    • Clinical evaluation and applications of the amplicor HBV monitorTM test, a quantitative HBV DNA PCR assay
    • Gerken G, Gomes J, Lampertico P, Colombo M, Rothaar T, Trippler M, et al. Clinical evaluation and applications of the amplicor HBV monitorTM test, a quantitative HBV DNA PCR assay. J Virol Methods. 74:1998;155-165.
    • (1998) J Virol Methods , vol.74 , pp. 155-165
    • Gerken, G.1    Gomes, J.2    Lampertico, P.3    Colombo, M.4    Rothaar, T.5    Trippler, M.6
  • 29
    • 0028009905 scopus 로고
    • PreS1 antigen/antibody patterns following interferon therapy in acute and chronic hepatitis B
    • Petit M, Zoulim F, Berthillon P, Capel F, Li J, Dauguet C, et al. PreS1 antigen/antibody patterns following interferon therapy in acute and chronic hepatitis B. J Hepatol. 20:1994;47-56.
    • (1994) J Hepatol , vol.20 , pp. 47-56
    • Petit, M.1    Zoulim, F.2    Berthillon, P.3    Capel, F.4    Li, J.5    Dauguet, C.6
  • 30
    • 0025299816 scopus 로고
    • Variable expression of pre-S1 antigen in serum during chronic hepatitis B virus infection: An accurate marker for the level of hepatitis B virus replication
    • Petit M, Zoulim F, Capel F, Dubanchet S, Dauguet C, Trépo C. Variable expression of pre-S1 antigen in serum during chronic hepatitis B virus infection: an accurate marker for the level of hepatitis B virus replication. Hepatology. 11:1990;809-814.
    • (1990) Hepatology , vol.11 , pp. 809-814
    • Petit, M.1    Zoulim, F.2    Capel, F.3    Dubanchet, S.4    Dauguet, C.5    Trépo, C.6
  • 32
    • 0002475105 scopus 로고    scopus 로고
    • A line probe assay for hepatitis B virus genotypes
    • In: Schinazi RFS, Sommadossi J-P, Thomas HC, editors London: International Medical Press
    • Van Geyt C, De Gendt S, Rombout A, Wyseur A, Maertens G, Rossau R, et al. A line probe assay for hepatitis B virus genotypes. In: Schinazi RFS, Sommadossi J-P, Thomas HC, editors. Therapies for Viral Hepatitis. London: International Medical Press. p. 139-45.
    • Therapies for Viral Hepatitis , pp. 139-145
    • Van Geyt, C.1    De Gendt, S.2    Rombout, A.3    Wyseur, A.4    Maertens, G.5    Rossau, R.6
  • 33
    • 0032897955 scopus 로고    scopus 로고
    • Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance
    • Pichoud C, Seignères B, Wang Z, Trepo C, Zoulim F. Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance. Hepatology. 29:1999;230-237.
    • (1999) Hepatology , vol.29 , pp. 230-237
    • Pichoud, C.1    Seignères, B.2    Wang, Z.3    Trepo, C.4    Zoulim, F.5
  • 34
    • 0025347975 scopus 로고
    • A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B
    • Perillo R, Schiff E, Davis G, Bodenheimer HC, Lindsay K, Payne J, et al. A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. N Engl J Med. 323:1990;295-301.
    • (1990) N Engl J Med , vol.323 , pp. 295-301
    • Perillo, R.1    Schiff, E.2    Davis, G.3    Bodenheimer, H.C.4    Lindsay, K.5    Payne, J.6
  • 35
    • 0001242733 scopus 로고    scopus 로고
    • Efficacy of famciclovir in chronic hepatitis B: Results of a dose finding study
    • (abstract 247)
    • Trépo C, Jezek P, Atkinson G, Boon R. Efficacy of famciclovir in chronic hepatitis B: results of a dose finding study. Hepatology. 24:(188A):1996;. (abstract 247).
    • (1996) Hepatology , vol.24 , Issue.188 A
    • Trépo, C.1    Jezek, P.2    Atkinson, G.3    Boon, R.4
  • 37
    • 0026573670 scopus 로고
    • New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection
    • Zoulim F, Mimms L, Floreani M, Pichoud C, Chemin I, Kay A, et al. New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection. J Clin Microbiol. 30:1992;1111-1119.
    • (1992) J Clin Microbiol , vol.30 , pp. 1111-1119
    • Zoulim, F.1    Mimms, L.2    Floreani, M.3    Pichoud, C.4    Chemin, I.5    Kay, A.6
  • 38
    • 85031640316 scopus 로고    scopus 로고
    • Rapid detection of mutations in the promoter and the pre-core region of HBV genome: Correlation with viral persistence and disease activity
    • abstract 294
    • Grandjacques C, Pradat P, Stuyver L, Chevallier M, Chevallier P, Pichoud C, et al. Rapid detection of mutations in the promoter and the pre-core region of HBV genome: correlation with viral persistence and disease activity. Hepatology. 28:((4 (pt2))):1998;. abstract 294.
    • (1998) Hepatology , vol.28 , Issue.4 PART 2
    • Grandjacques, C.1    Pradat, P.2    Stuyver, L.3    Chevallier, M.4    Chevallier, P.5    Pichoud, C.6
  • 39
    • 0021365713 scopus 로고
    • Spontaneous reactivation of chronic hepatitis B virus infection
    • Davis GL, Hoofnagle JH, Waggoner JG. Spontaneous reactivation of chronic hepatitis B virus infection. Gastroenterology. 86:1984;230-235.
    • (1984) Gastroenterology , vol.86 , pp. 230-235
    • Davis, G.L.1    Hoofnagle, J.H.2    Waggoner, J.G.3
  • 41
    • 0030772798 scopus 로고    scopus 로고
    • Lamivudine therapy for chronic hepatitis B: A six month randomized dose-ranging study
    • Nevens F, Main J, Honkoop P, Tyrrell DL, Barber J, Sullivan MT, et al. Lamivudine therapy for chronic hepatitis B: a six month randomized dose-ranging study. Gastroenterology. 113:1997;1258-1263.
    • (1997) Gastroenterology , vol.113 , pp. 1258-1263
    • Nevens, F.1    Main, J.2    Honkoop, P.3    Tyrrell, D.L.4    Barber, J.5    Sullivan, M.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.