IGF-1 bioavailability is increased by resistance training in older women with low bone mineral density

Mechanisms of Ageing and Development

Volumn 113, Issue 2, 2000, Pages 75-83

  Parkhouse, Wade S ^a   Li, Chunmei ^a   Vanderhoek, Kimberly J ^a   Coupland, Dave C ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Ageing; Insulin like growth factor 1; Osteopenia; Resistance exercise

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

AGED; AGING; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; BONE DENSITY; BONE MINERAL; BONE STRENGTH; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; FEMALE; HUMAN; OSTEOPENIA; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRAINING;

AGED; AGED, 80 AND OVER; AGING; BIOLOGICAL AVAILABILITY; BONE DENSITY; EXERCISE THERAPY; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MIDDLE AGED; WEIGHT LIFTING;

EID: 0033967378     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(99)00103-7     Document Type: Article

References (25)

1. Baxter R.C., Martin J.L. Binding proteins of insulin like growth factors: structure, regulation and function. Prog. Growth Factor Res. 1:1989;49-68.
2. Benbassat C.A., Maki K.C., Unterman T.G. Circulating levels of insulin-like growth factor (IGF) binding protein-1 and -3 ageing men: Relationship to insulin, glucose, IGF, and dehydroepiandrosterone sulfate and antFopometric measures. J Clin Endocrin. 82:1997;1484-1491.
3. Bermon S., Ferrari P., Bernard P., Altare S., Dolisi C. Responses of total and free insulin-like growth factor-1 and insulin-like growth factor binding protein-3 after resistance exercise and training in elderly subjects. Acta Physiol. Scand. :51-56. 165:1999;1999.
4. Boonen S., Lesaffre E., Dequeker J., Aerssens J., Nijs J., Pelemans W., Bouillon R. Relationship between baseline insulin-like growth factor-I (IGF-I) and femoral bone density in women aged over 70 years: potential implications for the prevention of age-related bone loss. J Am Geriatr Soc. 44. 1996:1996;1301-1306.
5. Breier B.H., Gallaher B.W., Cluckman P.D. Radioimmunoassay for insulin-like growth factor-1: solutions to some potential problems and pitfalls. J Endocrinol. 128:1991;347-357.
6. Chadan S.G., Dill R.P., Vanderhoek K., Parkhouse W.S. Influence of physical activity on plasma insulin-like growth factor-1 and insulin-like growth factor binding proteins in healthy older women. Mech. Ageing Dev. 109:1999;21-34.
7. Cohich W.S., Clemmons D.R. The insulin-like growth factors. Annu Rev Physiol. 55:1993;131-153.
8. Donahue L.R., Hunter S.J., Sherblom A.P., Rosen C. Age-related changes in serum insulin-like growth factor binding proteins in women. J. Clin. Endocrinol. Metab. 71:1990;575-579.
9. Hilding A., Hall K., Wivall-Helleryd I.L., Saaf M., Melin A.L., Thoren M. Serum levels of insulin-like growth factor I in 152 patients with growth hormone deficiency, aged 19-82 years, in relation to those in healthy subjects. J. Clin. Endocrinol. 84:1999;2013-2019.
10. Jones J.I., Clemmons D.R. Insulin-like growth factor-s and their binding proteins: biological actions. Endocrine Rev. 16:1995;3-34.
11. Kelijman M. Age-related alterations of growth hormone/insulin-like-growth-factor I axis. J. Clin. Endocrinol. Metab. : 1081-. 72:1991;1087.
12. Kraemer W.J., Marchitelli L., Gordon S.E. Hormonal and growth factor responses to heavy resistance exercise protocols. J. Appl. Physiol. 69:1990;1442-1450.
13. Kraemer W.J., Aquilera B.A., Terada M., Newton R.U., Lynch J.M., Rosendaal G., McBride J.M., Gordon S.E., Hakkien K. Responses of IGF-I to endogenous increases in growth hormone after heavy-resistance exercise. J. Appl. Physiol. 79(4):1995;1310-1315.
14. Kraemer R.R., Kilgor J.L., Kraemer G.R., Castracane V.D. Growth hormone, IGF-1 and testosterone responses to resistive exercise. Med. Sci. Sport Ex. 24:1992;1346-1352.
15. Langlois J.A., Rosen C.J., Visser M., Hannan M.T., Harris T., Wilson P.W.F., Kiel D.P. Association between insulin-like growth factor-1 and bone mineral density in older women and men: The Framington Heart Study. J. Clin. Endocrinol. Metab. 83:1998;4257-4262.
16. Laughlin G.A., Yen S.S.C. Nutrional and endocrine-metabolic aberrations in ammenorrheic athletes. J. Clin. Endocrin. Metab. 81:1996;4301-4309.
17. Nicklas B.J., Ryan A.J., Treuth M.M. Testosterone, growth hormone and IGF-1 responses to acute and chronic resistive exercise in men aged 55-70 years. Int. J. Sports Med. 16:1995;445-450.
18. Nyomba B.L., Berard L., Murphy L.J. Free insulin-like growth factor-1 (IGF-1) in healthy subjects: relationship with IGF-binding proteins and insulin sensitivity. J. Clin. Endocrinol. Metab. 82:1997;2177-2181.
19. Poehlman E.T., Copeland K.C. Influence of physical activity on insulin-like growth factor-1 in healthy younger and older men. J. Clin. Endocrinol. Metab. 71:1990;1468-1473.
20. Poehlam E.T., Rosen L.J., Copeland K.C. The influence of endurance training on IGF-1 in older individuals. Metabolism. 43(1):1994;1401-1405.
21. Pyka G., Wisell R.A., Marcus R. Age-dependent effects of resistance exercise on growth hormone secretion in people. J. Clin. Endrocrin. Metab. 75:1992;404-407.
22. Ravn P., Overgaard K., Spencer E.M., Christiansen C. Insulin-like growth factors I and II in healthy women with and without established osteoporosis. Eur. J. Endocrinol. 132:1995;313-319.
23. Rudman D. Growth hormone, body composition and aging. J. Am. Geriatr. Soc. 12:1985;800-807.
24. Ryan A.S., Treuth M.S., Rubin M.A., Millar J.P., Nicklas B.J., Landis D.M., Pratley R.E., Libanati C.R., Gundberg C.M., Hurley B.F. Effects of strength training on bone mineral density: hormonal and bone turnover relationships. J. Appl. Physiol. 77:1994;1678-1684.
25. Wood W.I., Cachianes G., Henzel W.J., Winslow G.A., Spencer S.A., Hellmiss R., Martin J., Baxter R.C. Cloning and expression of the growth hormone dependant insulin like growth factor-binding protein. Mol. Endocrin. 2:1988;1175-1185.