Clinical significance of the t(14; 18) and BCL2 overexpression in follicular large cell lymphoma

Leukemia and Lymphoma

Volumn 36, Issue 5-6, 2000, Pages 513-523

  Weisenburger, Dennis D ^a,b   Gascoyne, Randy D ^d   Bierman, Philip J ^a   Shenkier, Tamara ^d   Horsman, Douglas E ^d   Lynch, James C ^c   Chan, Wing C ^a   Greiner, Timothy C ^a   Connors, Joseph M ^d   Vose, Julie M ^a   Armitage, James O ^a   Sanger, Warren G ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

BCL2; Cytogenetics; Follicular large cell lymphoma; Follicular lymphoma; Non Hodgkin's lymphoma; T(14; 18)

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; PROTEIN BCL 2;

ADULT; ARTICLE; B CELL LYMPHOMA; CANCER GRADING; CANCER SURVIVAL; CHROMOSOME 17P; CHROMOSOME TRANSLOCATION 14; CHROMOSOME TRANSLOCATION 18; CLINICAL ARTICLE; FOLLICULAR LYMPHOMA; HUMAN; HUMAN TISSUE; LARGE CELL LYMPHOMA; PREDICTION; PRIORITY JOURNAL; PROTO ONCOGENE; TRISOMY 21;

EID: 0033966462     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009148399     Document Type: Article

References (47)

1. The Non-Hodgkin's Lymphoma Pathologic Classification Project. (1981) National Cancer Institute sponsored study of classification of non-Hodgkin's lymphomas. Summary and description of a working formulation for clinical usage. Cancer, 49, 2112-35.
2. Kantarjian, H.M., McLaughlin, P., Fuller, L.M., Dixon, D.O., Osborne, B.M. and Cabanillas, F.F. (1984) Follicular large cell lymphoma: Analysis and prognostic factors in 62 patients. J. Clin. Oncol., 2, 811-19.
3. Bartlett, N.L., Rizeq, M., Dorfman, R.F., Halpern, J. and Horning, S.J. (1994) Follicular large-cell lymphoma: Intermediate or low grade? J. Clin. Oncol, 12, 1349-57.
4. Martin, A.R., Weisenburger, D.D., Chan, W.C., Ruby, E.I., Anderson, J.R., Vose, J.M., Bierman, P.J., Bast, M.A., Daley, D.T. and Armitage, J.O. (1995) Prognostic value of cellular proliferation and histologic grade in follicular lymphoma. Blood, 85, 3671-78.
5. Wendum, D., Sebban, C., Gaulard, P., Coiffier, B., Tilly, H., Cazals, D., Boehn, A., Casasnovas, R.O., Bouabdallah, R., Jaubert, J., Ferrant, A., Diebold, J., de Mascarel, A. and Gisselbrecht, C., for the Group d'Etude des Lymphomes de l'Adulte. (1997) Follicular large-cell lymphoma treated with intensive chemotherapy: Analysis of 89 cases included in the LNH87 trial and comparison with the outcome of diffuse large B-cell lymphoma. J. Clin. Oncol., 15, 1654-63.
6. Armitage, J.O. and Weisenburger, D.D., for the Non-Hodgkin's Lymphoma Classification Project. (1998) New approach to classifying non-Hodgkin's lymphomas: Clinical features of the major histologic types. J. Clin. Oncol., 16, 2780-95.
7. Miller, T.P., LeBlanc, M., Grogan, T.M. and Fischer, R.I. (1997) Follicular lymphomas: Do histologic subtypes predict outcome? Hematol. Oncol. Clin. North Am., 11, 893-900.
8. Yunis, J.J., Frizzera, G., Oken, M.M., McKenna, J., Theologides, A. and Arneson, M. (1987) Multiple recurrent genomic defects in follicular lymphoma. N. Engl. J. Med., 316, 79-84.
9. Weiss, L.M., Warnke, R.A., Sklar, J. and Cleary, M.L. (1987) Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas. N. Engl. J. Med., 317, 1185-89.
10. Offit, K., Jhanwar, S.C., Ladanyi, M., Filippa, D.A. and Chaganti, R.S.K. (1991) Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: Correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment. Genes Chrom. Cancer, 3, 189-201.
11. Zelenetz, A.D., Chu, G., Galili, N., Bangs, C.D., Horning, S.J., Donlon, T.A., Cleary, M.L. and Levy, R. (1991) Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis. Blood, 78, 1552-60.
12. Tilly, H., Rossi, A., Stomatoullas, A., Lenormand, B., Bigorgne, C., Kunlin, A., Monconduit, M. and Bustard, C. (1994) Prognostic value of chromosomal abnormalities in follicular lymphoma. Blood, 84, 1043-49.
13. Turner, G.E., Ross, F.M. and Krajewski, A.S. (1995) Detection of t(14;18) in British follicular lymphoma using cytogenetics, Southern blotting and the polymerase chain reaction. Br. J. Haematol., 89, 223-25.
14. Horsman, D.E., Gascoyne, R.D., Coupland, R.W., Coldman, A.J. and Adomat, S.E. (1995) Comparison of cytogenetic analysis, Southern analysis, and polymerase chain reaction for the detection of t(14;18) in follicular lymphoma. Am. J. Clin. Pathol., 103, 472-78.
15. Poetsch, M., Weber-Matthiesen, K., Plendl, H.J., Grote, W. and Schlegelberger, B. (1996) Detection of the t(14;18) chro7 mosomal translocation by interphase cytogenetics with yeast-artificial chromosome probes in follicular lymphoma and nonneoplastic lymphoproliferation. J. Clin. Oncol., 14, 963-69.
16. Meijerink, J.P.P. (1997) t(14;18), a journey to eternity. Leuk., 11, 2175-87.
17. Shibata, D., Hu, E. Weiss, L.M., Brynes, R.K. and Nathwani, B.N. (1990) Detection of specific t(14;18) chromosomal translocations in fixed tissues. Hum. Pathol., 21, 199-203.
18. Pezzella, F., Jones, M., Ralfkiaer, E., Ersboll, J., Gatter, K.C. and Mason, D.Y. (1992) Evaluation of bcl-2 protein expression and 14;18 translocations as prognostic markers in follicular lymphoma. Br. J. Cancer, 65, 87-89.
19. Gaulard, P., d'Agay, M.F., Peuchmaur, M., Brousse, N., Gisselbrecht, C., Solol-Celigny, P., Diebold, J. and Mason, D.Y. (1992) Expression of the bcl-2 gene product in follicular lymphoma. Am. J. Pathol., 140, 1089-95.
20. Liu, J., Johnson, R.M. and Traweek, S.T. (1993) Rearrangement of the bcl-2 gene in follicular lymphoma. Diagn. Mol. Pathol., 2, 241-47.
21. Utz, G.L. and Swerdlow, S.H. (1993) Distinction of follicular hyperplasia from follicular lymphoma in B5-fixed tissues: Comparison of MT2 and bcl-2 antibodies. Hum. Pathol., 24, 1155-58.
22. Gelb, A.B., Rouse, R.V., Dorfman, R.F. and Warnke, R.A. (1994) Detection of immunophenotypic abnormalities in paraffin-embedded B-lineage non-Hodgkin's lymphomas. Am. J. Clin. Pathol., 102, 825-34.
23. Lai, R., Arber, D.A., Chang, K.L., Wilson, C.S. and Weiss, L.M. (1998) Frequency of bcl-2 expression in non-Hodgkin's lymphoma: A study of 778 cases with comparison of marginal zone lymphoma and monocytoid B-cell hyperplasia. Mod. Pathol., 11, 864-69.
24. Hermine, O., Haioun, C., Lepage, E., d'Agay, M.F., Brieve, J., Lavignac, C., Fillet, G., Salles, G., Marolleau, J.P., Diebold, J., Reyes, F., Gaulard, P., for the Groupe d'Etude des Lymphomes de l'Adulte (GELA). (1996) Prognostic significance of bcl-2 protein expression in aggressive non-Hodgkin's lymphoma. Blood, 87, 265-72.
25. Hill, M.E., MacLennan, K.A. Cunningham, D.C., Vaughan Hudson, B., Burke, M., Clarke, P., Di Stefano, F., Anderson, L., Vaughn Hudson, G., Mason, D., Selby, P. and Linch, D.C. (1996) Prognostic significance of BCL-2 expression and bcl-2 major breakpoint region rearrangement in diffuse large cell non-Hodgkin's lymphoma: A British National Lymphoma Investigation study. Blood, 88, 1046-51.
26. Gascoyne, R.D., Adomat, S.A., Krajewski, S., Krajewski, M., Horsman, D.E., Tolcher, A.W., O'Reilly, S.E., Hoskins, P., Coldman, A.J., Reed, J.C. and Connors, J.M. (1997) Prognostic significance of BCL-2 protein expression and BCL-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma. Blood, 90, 244-51.
27. Kramer, M.H.H., Hermans, J., Wijburg, E., Phillipo, K., Geelen, E., vanKrieken, J.H.J.M., de Jong, D., Maartense, E., Schuuring, E. and Kluin, P.M. (1998) Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood, 92, 3152-62.
28. Yunis, J.J., Mayer, M.G., Arnesen, M.A., Aeppli, D.P., Oken, M.M. and Frizzera, G. (1989) bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma. N. Engl. J. Med., 320, 1047-54.
29. Mann, R.B. and Berard, C.W. (1983) Criteria for the cytologic subclassification of follicular lymphomas: A proposed alternative method. Hematol, Oncol., 1, 187-92.
30. Vose, J.M., Anderson, J.R., Bierman, P.J., Bast, M., Weisenburger, D.D., Chan, W.C., Bishop, M.R. and Armitage, J.O. (1994) Comparison of front-line chemotherapy for aggressive non-Hodgkin's lymphoma using the CAP-BOP regimens. Sem. Hematol., 31, 4-8.
31. Hoskins, P.J., Le, N., Gascoyne, R.D., Klasa, R., Shenkier, T., O'Reilly, S.E. and Connors, J.M. (1997) Advanced diffuse large-cell lymphoma treated with 12-week combination chemotherapy: Natural history of relapse after initial complete response and prognostic variables defining outcome after relapse. Ann. Oncol., 8, 1125-32.
32. Nashelsky, M.B., Hess, M.M., Weisenburger, D.D., Pierson, J.C., Bast, M.A., Armitage, J.O. and Sanger, W.G. (1994) Cytogenetic abnormalities in B-immunoblastic lymphoma. Leuk. Lymphoma. 14, 415-20.
33. Cancer Cytogenetics: Supplement to An International System tbr Human Cytogenetic Nomenclature. (1991) Basel: S Karger Publishers, Inc.
34. Gribben, J.G., Freedman, A.S., Woo, S.D., Blake, K., Shu, R.S., Freeman, G., Longtine, J.A., Pinkus, G.S. and Nadler, L.M. (1991) All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment. Blood, 78, 3275-80.
35. Sharp, J.G., Bishop, M., Chan, W.C., Joshi, S.S., Kessinger, A., Mann, S.L., Murphy, B.O., Pirruccello, S., Reed, B., Sanger, W., Traystman, M., Vose, J., Weekes, C. and Wu, G. (1997) Application of malignant cell detection techniques to improve the outcome of high-dose therapy and transplantation for lymphoma, leukemia and breast cancer. In Hematopoietic Stem Cell: The Method Manual, edited by E. Wunder, Basel: Karger (in press).
36. Hsu, S.M., Raine, L. and Fanger, H. (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. Histochem. Cytochem., 29, 577-80.
37. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. (1993) A predictive model for aggressive non-Hodgkin's lymphoma. N. Engl. J. Med., 329, 987-94.
38. Kaplan, G.L. and Meier, P. (1958) Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc., 53, 457-81.
39. Monni, O., Joensuu, H., Fransilla, K., Klefstrom, J., Alitalo, K. and Knuutila, S. (1997) BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma. Blood, 90, 1168-74.
40. Levine, E.G., Arthur, D.C., Frizzera, G., Peterson, B.A., Hurd. D.D. and Bloomfield, C.D. (1988) Cytogenetic abnormalities predict clinical outcome in non-Hodgkin's lymphoma. Ann. Int. Med., 108, 14-20.
41. Johnson, A., Brun, A., Dictor, M., Rambech, E., Akerman, M. and Anderson, H. (1995) Incidence and prognostic significance of the t(14;18) in follicle center cell lymphoma of low and high grade. Ann. Oncol., 6, 789-94.
42. Simonian, P.L., Didier, A.M., Grillot, A.M. and Nunez, G. (1997) Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. Blood, 90, 1208-16.
43. Zhou, P., Qian, L., Kozopas, K.M. and Craig, R.N. (1997) Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood, 89, 630-43.
44. Sander, C.A., Yono, T., Clark, H.M., Harris, C., Longo, D.L., Jaffe, E.S. and Raffeld, M. (1993) p53 mutation is associated with progression in follicular lymphoma. Blood, 82, 1994-2004.
45. Lo Coco, F., Gaidano, G., Louie, D.C., Offit, K., Chaganti, R.S.K. and Dalla-Favera, R. (1993) p53 mutations are associated with histologic transformation of follicular lymphoma. Blood, 82, 2289-95.
46. Lister, T.A. (1997) Follicular lymphoma: Grounds for optimism. Ann. Oncol., 8 (Suppl. 1), S89-S92.
47. Tormo, M., Tari, A.M., McDonnell, T.J., Cabanillas, F., Garcia-Conde, T. and Lopez-Berestein, G. (1998) Apoptotic induction in transformed follicular lymphoma cells by bcl-2 downregulation. Leuk. Lymphoma, 30, 367-79.