T cells expressing the γδ T cell receptor induce apoptosis in cardiac myocytes

Cardiovascular Research

Volumn 45, Issue 3, 2000, Pages 579-587

  Huber, Sally A ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Apoptosis; Cell culture isolation; Immunology; Myocarditis; Myocytes

Indexed keywords

FAS ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CELL CULTURE; CELL ISOLATION; COXSACKIE VIRUS B3; FLOW CYTOMETRY; HEART MUSCLE CELL; HEART MUSCLE INJURY; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; VIRUS PATHOGENESIS;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOTOXICITY TESTS, IMMUNOLOGIC; FLOW CYTOMETRY; IN SITU NICK-END LABELING; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDITIS; MYOCARDIUM; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 0033964817     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(99)00267-9     Document Type: Article

References (52)

1. Huber S.A., Gauntt C.J., Sakkinen P. Enteroviruses and myocarditis: Viral pathogenesis through replication, cytokine induction and immunopathogenicity. Advances in Virus Research. 51:1998;35-80.
2. Huber S. Animal models of human disease - Autoimmunity in myocarditis: Relevance of animal models. Clin Immunol Immunopathol. 83:1997;93-102.
3. Bowles N., Richardson P., Olsen E., Archard L. Detection of coxsackie B virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy. Lancet. I:1986;1120-1122.
4. Kandolf R., Hofschneider P. Viral heart diseases. Springer Semin Immunopathol. 11:1989;1-13.
5. Archard L., Bowles N., Cunningham L., et al. Molecular probes for detection of persisting enterovirus infection of human heart and their prognostic value. Eur Heart J. 12:1991;56-59.
6. Olsen E. Prognosis of dilated cardiomyopathy: The value of endomyocardial biopsies. Sekiguchi M. Prognosis and treatment of cardiomyopathies and myocarditis. 1994;121-127 University of Tokyo Press, Tokyo.
7. Hiramitsu S., Morimoto S., Uemura A., et al. Long term outcome of 28 patients with viral or idiopathic myocarditis. 1994;University of Tokyo Press, Tokyo.
8. McManus B., Chow L., Wilson J., et al. Direct myocardial injury by enterovirus: A central role in the evolution of murine myocarditis. Clin Immunol Immunopathol. 68:1993;159-169.
9. Badorff C., Lee G., Lamphear B., et al. Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nature Med. 5:1999;320-326.
10. Wessely R., Klingel K., Santana L., et al. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J Clin Invest. 102:1998;1444-1453.
11. Neumann D., Rose N., Ansari A., Herkowitz A. Induction of multiple heart autoantibodies in mice with coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis. J Immunol. 152:1994;343-350.
12. Neu N., Beisel K., Traystman M., Rose N., Craig S. Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3-induced myocarditis. J Immunol. 138:1987;2488-2492.
13. Huber S., Lodge P. Coxsackievirus B3 myocarditis in Balb/c mice: Evidence for autoimmunity to myocyte antigens. Am J Path. 116:1984;21.
14. Lowenstein C., Hill S., Lafond-Walker A., et al. Nitric oxide inhibits viral replication in murine myocarditis. J Clin Invest. 97:1996;1837-1843.
15. Iwasaki A., Matsumori A., Yamada T., et al. Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthetase in a murine model of viral myocarditis. J Am Coll Cardiol. 33:1999;1400-1407.
16. Matsumori A. The use of cytokine inhibitors. A new therapeutic insight into heart failure. Int J Cardiol. 62:(Suppl. 1):1997;S3-S12.
17. Kasjtura J., Mansukhani M., Cheng W., et al. Programmed cell death and the expression of the protooncogene Bcl-2 in myocytes during postnatal maturation of the heart. Exp Cell Res. 219:1995;110-121.
18. James T. Normal and abnormal consequences of apoptosis in the human heart: From postnatal morphogenesis to paroxysmal arrhythmias. Circ. 90:1994;556-573.
19. James T., Nichols M., Sapire D., DiParre P., Lopez S. Complete heart block and fatal right ventricular failure in an infant. Circ. 93:1996;1588-1600.
20. Kajstura J., Cheng W., Reiss K., et al. Apoptotic and necrotic myocyte deaths are independent contributing variables of infarct size in rats. Lab Invest. 74:1996;86-107.
21. Mallat Z., Tedgui A., Fontaliran F., et al. Evidence of apoptosis in arrhythmogenic right ventricular dysplasia. N Engl J Med. 335:1996;1190-1196.
22. Narula J., Haider N., Virmani R., et al. Apoptosis in myocytes in end-stage heart failure. N Engl J Med. 335:1996;1182-1189.
23. Kawano H., Okada R., Kawano Y., Sueyoshi N., Shirai T. Apoptosis in acute and chronic myocarditis. Jpn Heart J. 35:1994;745-750.
24. Seki Y., Kai H., Muraishi A., Adachi K., Imaizumi T. Myocardial DNA strand breaks are detected in biopsy tissues from patients with dilated cardiomyopathy. Clin Cardiol. 21:1998;591-596.
25. Toyozaki T., Hiroe M., Tanaka M., et al. Levels of soluble Fas ligand in myocarditis. Am J Cardiol. 82:1998;246-248.
26. Huber S. Coxsackievirus-induced myocarditis is dependent on distinct immunopathogenic responses in different strains of mice. Lab Invest. 76:1997;691-701.
27. Hamrell B., Huber S., Leslie K. Reduced unloaded sarcomere shortening velocity and a shift to a slower myosin isoform in acute murine coxsackievirus myocarditis. Circ Res. 75:1994;462-472.
28. Huber S, Hamrell B, Knowlton K. Lessons from animal models of viral myocarditis. In: Schultheiss H-P, Schwimmbeck P (Eds.), Role of Immune Mechanism in Heart Disease. Springer-Verlag, Berlin, 1996:35-43.
29. Huber S., Mortensen A., Moulton G. Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of Balb/c mice initiated by cells expressing the y8+ T cell receptor. J Virol. 70:1996;3039-3045.
30. Born W., Happ M., Dallas A., et al. Recognition of heat shock proteins and gamma delta cell function. Immunol Today. 11:1990;40-43.
31. Suda T., Okazaki Y., Naito T., et al. Expression of the Fas ligand in cells of the T lineage. J Immunol. 154:1995;3806-3813.
32. LeMeur M., Gerlinger P., Benoit C., Mathis D. Correcting an immune-response deficiency by creating Ea gene transgenic mice. Nature. 316:1985;38-42.
33. Huber S., Stone J., Wagner D. Jr., et al. Gamma delta-positive T cells regulate MHC class II (IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis. J Virol. 73:1999;5630-5636.
34. Knowlton K., Jeon E., Berkley N., Wessely R., Huber S. A mutation in the puff region of VP2 attenuates the myocarditic penotype of an infectious cDNA of the Woodruff variant of coxsackievirus B3. J Virol. 70:1996;7811-7818.
35. Huber S., Job L., Woodruff J. Sex-related differences in the pattern of coxsackievirus B3-induced immune spleen cell cytotoxicity against virus-infected myofibers. Infect Immunology. 32:1981;68-73.
36. Huber S., Job L., Woodruff J. Lysis of infected myofibers by coxsackievirus B3 immune T lymphocytes. Am J Pathol. 98:1979;681-694.
37. Henke A., Huber S., Stelzner A., Whitton J. The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis. J Virol. 69:1995;6720-6728.
38. Kataoka T., Shinohara N., Takayama H., et al. A powerful tool for characterization and estimation of contribution of perforin and Fas based lytic pathways in cell mediated cytotoxicity. J Immunol. 156:1996;3678.
39. Tschopp J., Nabholz M. Perforin-mediated target cell lysis by cytolytic T lymphocytes. Ann Rev Immunol. 8:1996;279-302.
40. Nagata S., Golstein P. The Fas death factor. Science. 267:1995;1449-1456.
41. Zakeri Z., Bursch W., Tenniswood M., Lockshin R. Cell death: Programmed, apoptosis, necrosis, or other. Cell death and differentiation. Cell Death Diff. 2:1995;87-94.
42. Raff M. Cell suicide for beginners. Nature. 396:1998;119-122.
43. Talanian R., Yange X., Turbov J., et al. Granule-mediated killing: Pathways for granzyme B-initiated apoptosis. J Exp Med. 186:1997;1323-1331.
44. Seko T., Shinkai Y., Kawasaki A. Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3. Circulation. 84:1991;788-795.
45. Young L., Joag S., Zheng L., Lee Y., Young J. Perforin-mediated myocardial damage in acute myocarditis. Lancet. 336:1990;1019-1021.
46. Gebhard J., Perry C., Harkins S., et al. Coxsackievirus B3-induced myocarditis: Perforin exacerbates disease, but plays no detectable role in virus clearance. Am J Pathol. 153:1998;417-428.
47. Felzen B., Shilkrut M., Less H., et al. Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytolytic T lymphocytes from perforin-deficient mice: A major role for inositol 1,4,5-triphosphate. Circ Res. 82:1998;438-450.
48. Colston J., Chandrasekar B., Freeman G. Expression of apoptosis-related proteins in experimental coxsackievirus myocarditis. Cardiovasc Res. 38:1998;158-168.
49. Huber S. Heat-shock protein induction in adriamycin and picornavirus-infected cardiocytes. Lab Invest. 67:1992;218-224.
50. Sciammas R., Johnson R.M., Sperling A.I., et al. Unique antigen recognition by a herpes virus-specific gamma delta cell. J Immunol. 152:1994;5392-5397.
51. Heng M.K., Heng M.C. Heat-shock protein 65 and activated gamma/delta T cells in injured arteries. Lancet. 344:1994;921-923.
52. Kanda T., Nakano M., Yokoyama T., et al. Heat stress aggravates viral myocarditis in mice. Life Sci. 64:1999;93-101.