A note on a conditional-likelihood approach for family-based association studies of candidate genes

Human Heredity

Volumn 50, Issue 3, 2000, Pages 194-200

  Hsu, Li ^a   Zhao, Lue Ping ^a   Aragaki, Corinne ^a  

^a USA   (United States)

Author keywords

Ascertainment adjusted likelihood; Association analysis; Candidate genes; Conditional likelihood; Family studies; Penetrance function

Indexed keywords

ARTICLE; FAMILY STUDY; GENETIC HETEROGENEITY; GENOTYPE; HUMAN;

EID: 0033963924     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000022914     Document Type: Article

References (17)

1. Lander ES, Schork NJ: Genetic dissection of complex traits. Science 1994;265:2037-2048.
2. Elston RC: Linkage and association. Genet Epidemiol 1998;15:565-576.
3. Knowler WC, Williams RC, Pettitt DJ, et al: Gm and type II diabetes mellitus: An association in American Indians with genetic admixture. Am J Hum Genet 1988;43:520-526.
4. Blum K, Noble EP, Sheridan PJ, et al: Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA 1990;263:2055-2060.
5. Gelernter J, Goldman D, Risch N: The A1 allele at the D2 dopamine receptor gene and alcoholism: A reappraisal. JAMA 1993;169: 1673-1677.
6. Goldstein AM, Hodge SE, Haile RW: Selection bias in case-control studies using relatives as the controls. Int J Epidemiol 1989;18:985-989.
7. Curtis D, Sham PC: Population stratification can cause false positive linkage results if founders are untyped. Ann Hum Genet 1996;60: 261-263.
8. Witte JS, Gauderman WJ, Elston RC, Thomas DC: Bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs. Am J Epidemiol 1999;149:693-705.
9. Thomas DC, Gauderman WJ, Witte JS: Bias and efficiency in case-control studies of measured genes and gene-environment interactions: Multiple-case family designs (manuscript), 1998.
10. Thomas DC, Gauderman WJ, Witte JS: Bias and efficiency of measured genes and gene-environment interactions: Prospective vs. retrospective likelihoods (manuscript), 1998.
11. Breslow NE, Day NE: Statistical Methods in Cancer Research. Lyon, International Agency for Research on Cancer, 1980, vol 1.
12. Andrieu N, Goldstein AM: Use of relatives of cases as controls to identify risk factors when an interaction between environmental and genetic factors exists. Int J Epidemiol 1996;25: 649-657.
13. Prentice RL, Pyke R: Logistic disease incidence models and case-control studies. Biometrika 1979;66:403-411.
14. Prentice RL, Breslow NE: Retrospective studies and failure time models. Biometrika 1978: 65:153-158.
15. Liang K-Y: Odds ratio inference with dependent data. Biometrika 1985;72:678-682.
16. Zhao LP, Quiaoit F, Hsu L, Aragaki C: An efficient robust and unified framework for mapping complex trails. I. Two-point analysis. Am J Med Genet 1998;77:366-383.
17. Hodge SE, Elston RC: Lods, wrods, and mods: The interpretation of lod scores calculated under different models. Genet Epidemiol 1994; 11:329-342.