Altered reactivity of pulmonary vessels in postobstructive pulmonary vasculopathy

Journal of Applied Physiology

Volumn 88, Issue 1, 2000, Pages 17-25

  Shi, Weibin ^a   Hu, Fu ^a   Kassouf, Wassim ^a   Michel, René P ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Histamine; Pulmonary arteries; Pulmonary veins; Serotonin; Vascular remodeling

Indexed keywords

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY INJURY; ARTERY LIGATION; ARTICLE; CONTROLLED STUDY; EXPLANT; GUINEA PIG; HISTOPATHOLOGY; IMAGE ANALYSIS; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY DISEASE;

EID: 0033963215     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.88.1.17     Document Type: Article

References (33)

1. Abacioglu, N., Z. S. Ercan, L. Kanzik, H. Zengil, T. Demiryurek, and R. K. Turker. Endothelium-dependent relaxing effect of histamine on the isolated guinea pig main pulmonary artery strips. Agents Actions 22: 30-35, 1987.
2. Baumgartner, R. A., M. Wills-Karp, M. J. Kaufman, M. Munakata, and C. Hirshman. Serotonin induces constriction and relaxation of the guinea pig airway. J. Pharmacol. Exp. Ther. 255: 165-173, 1990.
3. Cowley, E. A., and D. H. Eidelman. Lung explants. In: Methods in Pulmonary Research, edited by S. Uhlig, and A. E. Taylor. Basel: Birkhauser, 1998, p. 57-70.
4. Cushing, D. J., and M. L. Cohen. Serotonin-induced relaxation in canine coronary artery smooth muscle. J. Pharmacol. Exp. Ther. 263: 123-129, 1992.
5. Dandurand, R. J., C. G. Wang, N. C. Phillips, and D. H. Eidelman. Responsiveness of individual airways to methacholine in adult rat lung explants. J. Appl. Physiol. 75: 364-372, 1993.
6. Furchgott, R. F., and P. M. Vanhoutte. Endothelium-derived relaxing and contracting factors. FASEB J. 3: 2007-2018, 1989.
7. Hofman, W. F., W. F. Jackson, H. el-Kashef, and I. C. Ehrhart. Modulation of vascular reactivity to serotonin in the dog lung. J. Appl. Physiol. 71: 217-222, 1991.
8. Hoshino, J., T. Sakamaki, T. Nakamura, M. Kobayashi, M. Kato, H. Sakamoto, T. Kurashina, A. Yagi, K. Sato, and Z. Ono. Exaggerated vascular response due to endothelial dysfunction and role of the renin-angiotensin system at early stage of renal hypertension in rats. Circ. Res. 74: 130-138, 1994.
9. Isaacson, T. C., V. Hample, E. K. Weir, D. P. Nelson, and S. L. Archer. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J. Appl. Physiol. 76: 933-940, 1994.
10. Ito, A., K. Egashira, T. Kadokami, Y. Fukumoto, T. Takayanagi, R. Nakaike, T. Kuga, K. Sueishi, H. Shimokawa, and A. Takeshito. Chronic inhibition of endothelium-derived nitric oxide synthesis causes coronary microvascular structural changes and hyperreactivity to serotonin in pigs. Circulation 92: 2636-2644, 1995.
11. Kelly, S. M., J. H. T. Bates, and R. P. Michel. Altered mechanical properties of lung parenchyma in postobstructive pulmonary vasculopathy. J. Appl. Physiol. 77: 2543-2551, 1994.
12. Kelly, S. M., J. H. T. Bates, and R. P. Michel. Respiratory mechanics and gas exchange in postobstructive pulmonary vasculopathy. Eur. Respir. J. 8: 202-208, 1995.
13. Michel, R. P. Arteries and veins of the normal dog lung: qualitative and quantitative structural differences. Am. J. Anat. 164: 227-241, 1982.
14. Michel, R. P., and T. S. Hakim. Increased resistance in postobstructive pulmonary vasculopathy: structure-function relationships. J. Appl. Physiol. 71: 601-610, 1991.
15. Michel, R. P., T. S. Hakim, and D. Petsikas. Segmental vascular resistance in postobstructive pulmonary vasculopathy. J. Appl. Physiol. 69: 1022-1032, 1990.
16. Michel, R. P., F. Hu, and B. O. Meyrick. Myoendothelial junctional complexes in postobstructive pulmonary vasculopathy: a quantitative electron microscopic study. Exp. Lung. Res. 21: 437-452, 1995.
17. Mulvany, M. J. Geometry, structure, and mechanics of resistance arteries. In: The Resistance Vasculature, edited by J. B. Bevan, W. Halpern, and M. J. Mulvany. New York: Humana, 1991, p. 115-125.
18. Mulvany, M. J., O. K. Hansen, and C. Aalkjaer. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ. Res. 43: 854-864, 1978.
19. Ortiz, J. L., C. Labat, X. Norel, I. Gorenne, J. Verley, and C. Brink. Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors. J. Pharmacol. Exp. Ther. 260: 762-767, 1992.
20. Orton, E. C., J. T. Reeves, and K. R. Stenmark. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension. J. Appl. Physiol. 65: 2459-2467, 1988.
21. Palmer, R. M. J., A. G. Ferrige, and S. Moncada. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526, 1987.
22. Rao, D. N., and A. I. Cederbaum. Production of nitric oxide and other iron-containing metabolites during the reductive metabolism of nitroprusside by microsomes and by thiols. Arch. Biochem. Biophys. 321: 363-371, 1995.
23. Sakuma, I., D. J. Stuehr, S. S. Gross, C. Nathan, and R. Levi. Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. USA. 85: 8664-8667, 1988.
24. Shi, W., P. Cernacek, F. Hu, and R. P. Michel. Endothelin reactivity and receptor profile of pulmonary vessels in postobstructive pulmonary vasculopathy. Am. J. Physiol. Heart Circ. Physiol. 273: H2558-H2564, 1997.
25. Shi, W., D. H. Eidelman, and R. P. Michel. Differential relaxant responses of pulmonary arteries and veins in lung explants of guinea pigs. J. Appl. Physiol. 83: 1476-1481, 1997.
26. Shi, W., A. Giaid, F. Hu, and R. P. Michel. Increased reactivity to endothelin of pulmonary arteries in long-term postobstructive pulmonary vasculopathy in rats. Pulm. Pharmacol. Ther. 11: 189-196, 1998.
27. Shi, W., C.-G. Wang, R. J. Dandurand, D. H. Eidelman, and R. P. Michel. Differential responses of pulmonary arteries and veins to histamine and 5-HT in lung explants of guinea pigs. Br. J. Pharmacol. 123: 1525-1532, 1998.
28. Stepp, D. W., and T. N. Tulenko. Alterations in basal and serotonin-stimulated calcium permeability and vasoconstriction in atherosclerotic aorta. Arterioscler. Thromb. 14: 1854-1859, 1994.
29. Vidone, R. A., and A. A. Liebow. Anatomical and functional studies of the lung deprived of pulmonary arteries and veins, with an application in the therapy of transposition of the great vessels. Am. J. Pathol. 33: 539-571, 1957.
30. Wang, C.-G., J. J. Almirall, C. S. Dolman, R. J. Dandurand, and D. H. Eidelman. In vitro bronchial responsiveness in two highly inbred rat strains. J. Appl. Physiol. 82: 1445-1452, 1997.
31. Wanstall, J. C., J. S. Thompson, and A. H. Morice. Effects of atrial natriuretic peptide and nitroprusside on isolated pulmonary resistance and conduit arteries from rats with pulmonary hypertension. Br. J. Pharmacol. 110: 1363-1368, 1993.
32. Weibel, E. R. Early stages in the development of collateral circulation to the lung in the rat. Circ. Res. 8: 353-376, 1960.
33. Wright, J. L., J. P. Sun, and A. Churg. Site of methacholine reactivity in the peripheral airways: analysis using lung explants. Am. J. Physiol.Lung Cell. Mol. Physiol. 272: L68-L72, 1997.