Differential relaxant responses of pulmonary arteries and veins in lung explants of guinea pigs

Journal of Applied Physiology

Volumn 83, Issue 5, 1997, Pages 1476-1481

  Shi, Weibin ^a   Eidelman, David H ^a   Michel, René P ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Acetylcholine; Endothelium; Histamine; Nitric oxide

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ACETYLCHOLINE; HISTAMINE; INDOMETACIN; N(G) NITROARGININE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PAPAVERINE;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL TONE; GUINEA PIG; IMAGE ANALYSIS; ISOLATED LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; VASODILATATION;

EID: 0030667319     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.5.1476     Document Type: Article

References (31)

1. Abacioglu, N., Z. S. Ercan, L. Kanzik, H. Zengil, T. Demiryurek, and R. K. Turker. Endothelium-dependent relaxing effect of histamine on the isolated guinea-pig main pulmonary artery strips. Agents Actions 22: 30-35, 1987.
2. 2. J. Pharmacol. Exp. Ther. 236: 535-541, 1986.
3. Aoki, H., J. Nishimura, S. Kobayashi, and H. Kanaide. Relationship between cytosolic calcium concentration and force in the papaverine-induced relaxation of medial strips of pig coronary artery. Br. J. Pharmacol. 111: 489-496, 1994.
4. Bansal, V., H. Toga, and J. U. Raj. Tone dependent nitric oxide production in ovine vessels in vitro. Respir. Physiol. 93: 249-260, 1993.
5. Bradley, J. D., P. B. Zanaboni, and T. E. Dahms. Species differences in pulmonary vasoactive responses to histamine, 5-hydroxytryptamine, and KCl. J. Appl. Physiol. 74: 139-146, 1993.
6. Cheng, D. Y., B. J. DeWitt, T. J. McMahon, and P. J. Kadowitz. Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H2416-H2422, 1994.
7. Cigarini, I., S. Adnot, P., E. Chabrier, I. Viossat, P. Braquet, and B. Gaujour. Pulmonary vasodilator responses to arterial natriuretic factor and sodium nitroprusside. J. Appl. Physiol. 67: 2269-2275, 1989.
8. Cumiskey, W. R., and M. E. Feigenson. Spasmolytic activity of cinnamedrine and papaverine in isolated rat uterine muscle. Arch. Int. Pharmacodyn. Ther. 263: 113-119, 1983.
9. Dandurand, R. J., C. G. Wang, N. C. Phillips, and D. H. Eidelman. Responsiveness of individual airways to methacholine in adult rat lung explants. J. Appl. Physiol. 75: 364-372, 1993.
10. Davidson, D., and A. Eldemerdash. Endothelium-derived relaxing factor: presence in pulmonary and systemic arteries of the newborn guinea pigs. Pediatr. Res. 27: 128-132, 1990.
11. Feletou, M., V. Girard, and E. Canet. Different involvement of nitric oxide in endothelium-dependent relaxation of porcine pulmonary artery and vein: influence of hypoxia. J. Cardiovasc. Pharmacol. 25: 665-673, 1995.
12. Ferrario, L., H. M. Amin, K. Sugimori, E. M. Camporesi, and T. S. Hakim. Site of action of endogenous nitric oxide on pulmonary vasculature in rats. Pflug. Arch. Eur. J. Physiol. 432: 523-527, 1996.
13. Furchgott, R. F., and P. M. Vanhoutte. Endothelium-derived relaxing and contracting factors. FASEB J. 3: 2007-2018, 1989.
14. Gao, Y., H. Zhao, and J. U. Raj. Endothelium-derived nitric oxide plays a larger role in pulmonary veins than in arteries of newborn lambs. Circ. Res. 76: 559-565, 1995.
15. Gao, Y., H. Zhao, and J. U. Raj. PAF induces relaxation of pulmonary arteries but contraction of pulmonary veins in the ferret. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H704-H709, 1995.
16. Ignarro L. J., G. M. Buga, and G. Chaudhuri. EDRF generation and release from perfused bovine pulmonary artery and vein. Eur. J. Pharmacol. 149: 79-88, 1988.
17. Ignarro, L. J., G. Ross, and J. Tillisch. Pharmacology of endothelium-derived nitric oxide and nitrovasodilators. West. J. Med. 154: 51-62, 1991.
18. Kalsner, S. Cholinergic constriction in the general circulation and its role in coronary artery spasm. Circ. Res. 65: 237-257, 1989.
19. Kramer, G. L., and J. N. Wells. Effects of phosphodiesterase inhibitors on cyclic nucleotide levels and relaxation of pig coronary arteries. Mol. Pharmacol. 16: 813-822, 1979.
20. Leeman, M., V. Z. de Beyl, M. Delcroix, and R. Naeije. Effects of endogenous nitric oxide on pulmonary vascular tone in intact dogs. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H2343-H2347, 1994.
21. Miller, V. M., and P. M. Vanhoutte. Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase. Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H432-H437, 1985.
22. Rao, D. N., and A. I. Cederbaum. Production of nitric oxide and other iron-containing metabolites during the reductive metabolism of nitroprusside by microsomes and by thiols. Arch. Biochem. Biophys. 321: 363-371, 1995.
23. Roos, C. M., G. F. Rich, D. R. Uncles, M. O. Daugherty, and D. U. Frank. Sites of vasodilation by inhaled nitric oxide vs. sodium nitroprusside in endothelin-constricted isolated rat lungs. J. Appl. Physiol. 77: 51-57, 1994.
24. Sakuma, I., D. J. Stuehr, S. S. Gross, C. Nathan, and R. Levi. Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. USA 85: 8664-8667, 1988.
25. Sata, T., E. Kubota, S. I. Said, and H. P. Misra. EPR spectroscopic studies of detection of a carbon-centered free radical during acetylcholine-induced and endothelium-dependent relaxation of guinea pig pulmonary artery. Free Radic. Res. Commun. 9: 213-222, 1990.
26. Satoh, H., and J. Inui. Endothelial cell-dependent relaxation and contraction induced by histamine in the isolated guinea-pig pulmonary artery. Eur. J. Pharmacol. 97: 321-324, 1984.
27. Shi, W., and R. P. Michel. Modulation of vasoreactivity to histamine in pulmonary vessels of guinea pigs (Abstract). Am. J. Respir. Crit. Care Med. 155: A789, 1997.
28. Stork, A. P., and T. M. Cocks. Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor. Br. J. Pharmacol. 113: 1099-1104, 1994.
29. Wennmalm, A. Endothelial nitric oxide and cardiovascular disease. J. Intern. Med. 235: 317-327, 1994.
30. Yang, Z. H., L. von Segesser, E. Bauer, P. Stulz, M. Turina, and T. F. Luscher. Different activation of the endothelial L-arginine and cyclooxygenase pathway in the human internal mammary artery and saphenous vein. Circ. Res. 68: 52-60, 1991.
31. Zhao, Y., C. S. Packer, and R. A. Rhoades. Pulmonary vein contracts in response to hypoxia. Am. J. Physiol. 265 (Lung Cell. Mol. Physiol. 9): L87-L92, 1993.