Differential responses of pulmonary arteries and veins to histamine and 5-HT in lung explants of guinea-pigs

British Journal of Pharmacology

Volumn 123, Issue 8, 1998, Pages 1525-1532

  Shi, Weibin ^a   Wang, Chong Gang ^b   Dandurand, Ron J ^b   Eidelman, David H ^b   Michel, René P ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

5 HT; Histamine; Lung culture; Morphometry; Nitric oxide; Pulmonary artery; Pulmonary vein; Vasoconstriction

Indexed keywords

AGAROSE; CHLORPHENIRAMINE; CIMETIDINE; HISTAMINE; HISTAMINE H2 RECEPTOR; INDOMETACIN; KETANSERIN; N(G) NITROARGININE; POTASSIUM CHLORIDE; SEROTONIN;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DIAMETER; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; GUINEA PIG; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; VASCULAR ENDOTHELIUM; VEIN DIAMETER; VENOCONSTRICTION;

ANIMALS; CYCLOOXYGENASE INHIBITORS; ENZYME INHIBITORS; GUINEA PIGS; HISTAMINE; HISTAMINE H1 ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE SYNTHASE; POTASSIUM CHLORIDE; PULMONARY ARTERY; PULMONARY VEINS; SEROTONIN;

EID: 0031916897     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701759     Document Type: Article

References (34)

1. ABACIOGLU, N., ERCAN, Z.S., KANZIK, L., ZENGIL, H., DEMIRYUREK, T. & TURKER, R.K. (1987). Endothelium-dependent relaxing effect of histamine on the isolated guinea-pig main pulmonary artery strips. Agents Actions, 22, 30-35.
2. ALBERT, R.K., LAMM, W.J., HENDERSON, W.R. & BOLIN, R.W. (1989). Effect of leukotrienes B4, C4, and D4 on segmental pulmonary vascular pressures. J. Appl. Physiol., 66, 458-464.
3. BEST, P.V. & HEATH, D. (1961). Interpretation of the appearances of the small pulmonary blood vessels in animals. Circ. Res., 9, 288-294.
4. BRADLEY, J.D., ZANABONI, P.B. & DAHMS, T.E. (1993). Species differences in pulmonary vasoactive responses to histamine, 5-hydroxytryptamine and KCl. J. Appl. Physiol., 74, 139-146.
5. CHEUNG, D.W. (1981). Electrical activity of the pulmonary veins and its interaction with the right atrium in the guinea-pig. J. Physiol., 314, 445-456.
6. CUSHING, D.J. & COHEN, M.L. (1992). Serotonin-induced relaxation in canine coronary artery smooth muscle. J. Pharmacol. Exp. Ther., 263, 123-129.
7. DANDURAND, R.J., WANG, C.G., PHILLIPS, N.C. & EIDELMAN, D.H. (1993). Responsiveness of individual airways to methacholine in adult rat lung explants. J. Appl. Physiol., 75, 364-372.
8. DOORNEKAMP, F.N.G., BORST, C. & POST, M.J. (1996). Endothelial cell recoverage and intimal hyperplasia after endothelium removal with or without smooth muscle cell necrosis in the rabbit carotid artery. J. Vasc. Res., 33, 146-155.
9. EL-KASHEF, H. (1996). Hyperglycemia increased the responsiveness of isolated rabbit's pulmonary arterial rings to serotonin. Pharmacology, 53, 151-159.
10. FELETOU, M., GIRARD, V. & CANET, E. (1995). Differential involvement of nitric oxide in endothelium-dependent relaxation of porcine pulmonary artery and vein: influence of hypoxia. J. Cardiovasc. Pharmacol., 25, 665-673.
11. FERENCZ, C. (1969). Pulmonary arterial design in mammals: morphologic variation and physiologic constancy. Johns Hopkins Med. J., 125, 207-224.
12. FURCHGOTT, R.F. & VANHOUTTE, P.M. (1989). Endothelium-derived relaxing and contracting factors. FASEB. J., 3, 2007-2018.
13. GAO, Y., ZHAO, H. & RAJ, J.U. (1995). PAF induces relaxation of pulmonary arteries but contraction of pulmonary veins in the ferret. Am. J. Physiol., 269, H704-H709.
14. GAO, Y., ZHAO, H. & RAJ, J.U. (1995). Endothelium-derived nitric oxide plays a larger role in pulmonary veins than in arteries of newborn lambs. Circ. Res., 76, 559-565.
15. HAKIM, T.S., MICHEL, R.P. & CHANG, H.K. (1982). Partitioning of pulmonary vascular resistance in dogs by arterial and venous occlusion. J. Appl. Physiol., 52, 710-715.
16. HOFMAN, W.F., JACKSON, W.F., EL-KASHEF, H. & EHRHART, I.C. (1991). Modulation of vascular reactivity to serotonin in the dog lung. J. Appl. Physiol., 71, 217-222.
17. HOLECYOVA, A., GEROVA, M., SMIESKO, V. & DOLEZEL, S. (1993). Contractility of the rabbit abdominal aorta 4 days after endothelium denudation. J. Vasc. Res., 30, 224-230.
18. HOYER, D., CLARKE, D.E., FOZARD, J.R., HARTIG, P.R., MARTIN, G.R., MYLECHARANE, E.J., SAXENA, P.R. & HUMPHREY, P.P. (1994). International Union of pharmacology classification of receptors for 5-hydroxytryptamine. Pharmacol. Rev., 46, 157-203.
19. KARAKI, H. & WEISS, G.B. (1988). Calcium release in smooth muscle. Life Sci., 42, 111-122.
20. KIMURA, M., MAEDA, K., HARASAWA, Y., OHNO, Y., NAKAMURA, M., SAKURAI, I. & HAYASHI, S. (1992). Recovery of endothelium-dependent responses by reseeding endothelial cells in culture onto the denuded coronary artery. J. Pharmacol. Exp. Ther., 262, 841-849.
21. LEVIN, E.R. (1995). Endothelins. N. Engl. J. Med., 333, 356-363.
22. MCLAUGHLIN, R.F., Jr. TYLER, W.S. & CANADA, R.O. (1966). Subgross pulmonary anatomy of the rabbit, rat, and guinea pig, with additional notes on the human lung. Am. Rev. Respir. Dis., 94, 380-387.
23. MICHEL, R.P. (1982). Arteries and veins of the normal dog lung: qualitative and quantitative structural differences. Am. J. Anat., 164, 227-241.
24. MICHEL, R.P. & HAKIM, T.S. (1991). Increased resistance in postobstructive pulmonary vasculopathy: structure-function relationships. J. Appl. Physiol., 71, 601-610.
25. MICHEL, R.P., HAKIM, T.S. & PETSIKAS, D. (1990). Segmental vascular resistance in postobstructive pulmonary vasculopathy. J. Appl. Physiol., 69, 1022-1032.
26. NEELY, C.F., HAILE, D. & MATOT, I. (1993). Tone-dependent responses of 5-hydroxytryptamine in the feline pulmonary vascular bed are mediated by two different 5-hydroxytryptamine receptors. J. Pharmacol. Exp. Ther., 264, 1315-1326.
27. PATON, W.D.M. (1975). The recording of mechanical responses of smooth muscle. In Methods in Pharmacology, ed. Daniel, E.E. & Paton, D.M. pp. 261-264. New York: Plenum press.
28. SAKUMA, L. STUEHR, D.J., GROSS, S.S., NATHAN, C. & LEVI, R. (1988). Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. U.S.A., 85, 8664-8667.
29. SELIG, W.M., BLOOMQUIST, M.A., COHEN, M.L. & FLEISCH, J.H. (1988). Serotonin-induced pulmonary responses in the perfused guinea pig lung: evidence for 5-HT2 receptor-mediated pulmonary vascular and airway smooth muscle constriction. Pulm. Pharmacol., 1, 93-99.
30. SHI, W., EIDELMAN, D.H. & MICHEL, R.P. (1997). Indomethacin potentiates acetylcholine (ACh)-induced relaxation in pulmonary arteries and veins of guinea pigs (Abstract). Am. J. Respir. Dis. Crit. Care Med., 155, 785A.
31. TODA, N. (1990). Mechanism underlying responses to histamine of isolated monkey and human cerebral arteries. Am. J. Physiol., 258, H311-H317.
32. 2-receptors in the guinea pig pulmonary vascular bed. Pharmacology, 9, 306-311.
33. VAN NUETEN, J.M., LEYSEN, J.E., DE CLERCK, F. & VANHOUTTE, P.M. (1984). Serotonergic receptor subtypes and vasoreactivity. J. Cardiovasc. Pharmacol., 6, S564-S574.
34. ZHAO, Y., PACKER, C.S. & RHOADES, R.A. (1993). Pulmonary vein contracts in response to hypoxia. Am. J. Physiol., 265, L87-L92.