Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells

British Journal of Pharmacology

Volumn 129, Issue 2, 2000, Pages 367-373

  Yamashita, Masamichi ^a,c   Kushihara, Mikie ^a   Hirasawa, Noriyasu ^a   Takasaki, Wataru ^b   Takahagi, Hidekuni ^b   Takayanagi, Motoaki ^c   Ohuchi, Kazuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

5 Lipoxygenase; Degranulation; Leukotriene; RBL 2H3 cell; Troglitazone; Zileuton

Indexed keywords

2,4 DINITROPHENOL; ANTIASTHMATIC AGENT; ANTIGEN; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; IMMUNOGLOBULIN E; LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE E4; MEMBRANE PHOSPHOLIPID; ORAL ANTIDIABETIC AGENT; PROSTAGLANDIN D2; SERUM ALBUMIN; TROGLITAZONE; ZILEUTON;

ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENCY; ENZYME IMMUNOASSAY; ENZYME INHIBITION; MAST CELL; MAST CELL DEGRANULATION; NEUTROPHIL; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL; RAT; SUPERNATANT;

EID: 0033960111     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703044     Document Type: Article

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