Neutrophils in induced sputum arise from central airways

European Respiratory Journal

Volumn 15, Issue 1, 2000, Pages 36-40

  Moodley, Y P ^a   Krishnan, V ^a   Lalloo, U G ^a  

^a UNIVERSITY OF NATAL   (South Africa)

Author keywords

Bronchial washings; Bronchoalveolar lavage; Central airways; Hypertonic saline nebulization; Induced sputum; Neutrophil

Indexed keywords

SODIUM CHLORIDE;

AIRWAY; ARTICLE; BRONCHUS SECRETION; CONTROLLED STUDY; FIBEROPTIC BRONCHOSCOPY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LEUKOCYTE COUNT; LUNG LAVAGE; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; SALIVA ANALYSIS; SPUTUM ANALYSIS; TISSUE DISTRIBUTION; TRACHEA MUCUS; TRACHEOBRONCHIAL TOILET;

ADULT; BRONCHI; BRONCHIAL PROVOCATION TESTS; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LEUKOCYTE COUNT; MALE; NEUTROPHILS; REFERENCE VALUES; SPUTUM; TRACHEA;

EID: 0033959712     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3003.2000.15a08.x     Document Type: Article

References (22)

1. Iredale MJ, Wanklyn AR, Phillips IP, Krausz T, Ind PW. Non-invasive assessment of bronchial inflammation in asthma: no correlation between eosinophilia of induced sputum and bronchial responsiveness to inhaled hypertonic saline. Clin Exp Allergy 1994; 24: 940-945.
2. Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996; 153: 530-534.
3. Pizzichini E, Pizzichini MM, Ethimiadis A. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 1996; 154: 308-317.
4. Fahy JV, Liu J, Wong H, Boushey HA. Analysis of cellular and biochemical constituents in induced sputum after allergen challenges: a method for studying allergic airway inflammation. J Allergy Clin Immunol 1994; 93: 1031-1039.
5. Keatings VM, Evans DJ, O'Connor BJ, Barnes PJ. Cellular profile in asthmatic airways: a comparison of induced sputum, bronchial washings and bronchoalveolar lavage fluid. Thorax 1997; 52: 372-374.
6. Maestrelli P, Saetta M, Di Stefano A, et al. Comparison of leukocyte counts in sputum, bronchial biopsies and bronchoalveolar lavage. Am J Respir Crit Care Med 1995; 152: 1926-1931.
7. Grootendorst DC, Sont JK, Willems LNA, et al. Comparison of inflammatory cell counts in asthma: induced sputum versus bronchoalveolar lavage and bronchial biopsies. Clin Exp Allergy 1997; 27: 769-779.
8. Holz O, Richter K, Jorres RA, Speckin P, Mucke M, Magnussen H. Changes in sputum composition between two inductions performed on consecutive days. Thorax 1998; 53: 83-86.
9. Nightingale JA, Rogers DF, Barnes PJ. Effect of repeated sputum induction on cell counts in normal volunteers. Thorax 1998; 53: 87-90.
10. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; i: 307-310.
11. Pizzichini MMM, Popov TA, Efthmiadis A, et al. Spontaneous and induced sputum to measure indices of airway inflammation in asthma. Am Rev Respir Dis 1996; 154: 866-869.
12. Rennard SI, Ghafouri MO, Thompson AB, et al. Fractional processing of sequential bronchoalveolar lavage to separate bronchial and alveolar samples. Am Rev Respir Dis 1990; 141: 208-217.
13. Diaz P, Galleguillos FR, Gonzalez MC, Pantin CFA, Kay AB. Bronchoalveolar lavage in asthma: the effect of disodium cromoglycate (cromolyn) on leukocyte counts, immunoglobulins and complement. J Allergy Clin Immunol 1984; 74: 41-48.
14. Jeffery PK, Wardlaw J, Nelson FC, Collins JV, Kay AB. Bronchial biopsies in asthma: an ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 1989; 140: 1745-1753.
15. Daviskas E, Anderson SD, Gonda I, et al. Inhalation of hypertonic saline aerosol enhances mucocilliary clearance in asthmatic and healthy subjects. Eur Respir J 1996; 9: 725-732.
16. Pizzichini E, Pizzichini MM, Efthimiadis A, Hargreave FE, Dolovich J. Measurement of inflammatory indices in induced sputum: effects of selection of sputum to minimize salivary contamination. Eur Respir J 1996; 9: 1174-1180.
17. Gershman NH, Wong HH, Liu JT, Mahlmeister MJ, Fahy JV. Comparison of two methods of collecting induced sputum in asthmatic subjects. Eur Respir J 1996; 9: 2448-2453.
18. In't Veen JCCM, de Gouw HWFM, Smits HH, et al. Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J 1996; 9: 2441-2447.
19. Pin J, Gibson PG, Kolendowicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47: 25-29.
20. Saltini C, Hance AJ, Ferrans VJ, Basset F, Bitterman PB, Crystal RG. Accurate quantification of cells recovered by bronchoalveolar lavage. Am Rev Respir Dis 1984; 130: 650-658.
21. Popov T, Gottschalk R, Kolendowicz R, Dolovich J, Powers P, Hargreave FE. The evaluation of a cell dispersion method of sputum examination. Clin Exp Allergy 1994; 24: 778-783.
22. Kips JC, Peleman RA, Pauwels RA. Methods of examining induced sputum: do differences matter? Eur Respir J 1998; 11: 529-533.