-
1
-
-
76549234433
-
Antibiotic substances from Basidiomycetes. VII. Clitocybe illudens
-
Anchel M, Hervey A, Robbins WJ. Antibiotic substances from Basidiomycetes. VII. Clitocybe illudens. Proc Natl Acad Sci USA 1950; 36: 30-36.
-
(1950)
Proc Natl Acad Sci USA
, vol.36
, pp. 30-36
-
-
Anchel, M.1
Hervey, A.2
Robbins, W.J.3
-
2
-
-
33947481529
-
The structures of the Basidiomycete metabolites Illudin S and Illudin M
-
McMorris TC, Anchel M. The structures of the Basidiomycete metabolites Illudin S and Illudin M. J Amer Chem Soc 1963; 85: 831-832.
-
(1963)
J Amer Chem Soc
, vol.85
, pp. 831-832
-
-
McMorris, T.C.1
Anchel, M.2
-
3
-
-
8244228308
-
Fungal metabolites. The structure of the novel sesquiterpenoids Illudin-S and -M
-
McMorris TC, Anchel M. Fungal metabolites. The structure of the novel sesquiterpenoids Illudin-S and -M. J Amer Chem Soc 1965; 87: 1594-1600.
-
(1965)
J Amer Chem Soc
, vol.87
, pp. 1594-1600
-
-
McMorris, T.C.1
Anchel, M.2
-
4
-
-
0023244069
-
Preclinical evaluation of illudins as anticancer agents
-
Kelner MJ, McMorris TC, Beck WT, Zamora IM, Taetle R. Preclinical evaluation of illudins as anticancer agents. Cancer Res 1987; 47: 3186-3189.
-
(1987)
Cancer Res
, vol.47
, pp. 3186-3189
-
-
Kelner, M.J.1
McMorris, T.C.2
Beck, W.T.3
Zamora, I.M.4
Taetle, R.5
-
5
-
-
0025168447
-
Preclinical evaluation of illudins as anticancer agents: Basis for selective cytotoxicity
-
Kelner MJ, McMorris TC, Taetle R. Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity. J Natl Cancer Inst 1990; 82: 1562-1565.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1562-1565
-
-
Kelner, M.J.1
McMorris, T.C.2
Taetle, R.3
-
6
-
-
0028168639
-
Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents
-
Kelner MJ, McMorris TC, Estes L, Rutherford M, Montoya M, Goldstein J, Samson K, Starr R, Taetle R. Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents. Biochem Pharmacol 1994; 48: 403-409.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 403-409
-
-
Kelner, M.J.1
McMorris, T.C.2
Estes, L.3
Rutherford, M.4
Montoya, M.5
Goldstein, J.6
Samson, K.7
Starr, R.8
Taetle, R.9
-
7
-
-
0029142483
-
In vitro and in vivo studies on the anticancer activity of dehydroilludin M
-
Kelner MJ, McMorris TC, Taetle R. In vitro and in vivo studies on the anticancer activity of dehydroilludin M. Anticancer Res 1995; 15: 873-878.
-
(1995)
Anticancer Res
, vol.15
, pp. 873-878
-
-
Kelner, M.J.1
McMorris, T.C.2
Taetle, R.3
-
8
-
-
0028883899
-
Efficacy of Acyltulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: Retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells
-
Kelner MJ, McMorris TC, Estes L, Starr RJ, Rutherford M, Montoya M, Samson KM, Taetle R. Efficacy of Acyltulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells. Cancer Res 1995; 55: 4936-4940.
-
(1995)
Cancer Res
, vol.55
, pp. 4936-4940
-
-
Kelner, M.J.1
McMorris, T.C.2
Estes, L.3
Starr, R.J.4
Rutherford, M.5
Montoya, M.6
Samson, K.M.7
Taetle, R.8
-
9
-
-
0029800935
-
Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents
-
Kelner MJ, McMorris TC, Estes L, Wang W, Samson KM, Taetle R. Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents. Invest New Drugs 1996; 14: 161-167.
-
(1996)
Invest New Drugs
, vol.14
, pp. 161-167
-
-
Kelner, M.J.1
McMorris, T.C.2
Estes, L.3
Wang, W.4
Samson, K.M.5
Taetle, R.6
-
10
-
-
0031031009
-
Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S
-
MacDonald JR, Muscoplat CC, Dexter DL, Mangold GL, Chen SF, Kelner MJ, McMorris TC, Von Hoff DD. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S. Cancer Res 1997; 57: 279-283.
-
(1997)
Cancer Res
, vol.57
, pp. 279-283
-
-
MacDonald, J.R.1
Muscoplat, C.C.2
Dexter, D.L.3
Mangold, G.L.4
Chen, S.F.5
Kelner, M.J.6
McMorris, T.C.7
Von Hoff, D.D.8
-
11
-
-
0032077401
-
Efficacy of MGI 114 against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft
-
Kelner MJ, McMorris TC, Estes L, Samson KM, Bagnell RD, Taetle R. Efficacy of MGI 114 against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft. Eur J Cancer 1998; 34: 908-913.
-
(1998)
Eur J Cancer
, vol.34
, pp. 908-913
-
-
Kelner, M.J.1
McMorris, T.C.2
Estes, L.3
Samson, K.M.4
Bagnell, R.D.5
Taetle, R.6
-
12
-
-
0000763311
-
In vitro antitumor activity of MGI 114 in combination with topotecan, cisplatin, etoposide, or gemcitabine
-
Barrera H, MacDonald JR, Hilsenbeck S, Weitman S. In vitro antitumor activity of MGI 114 in combination with topotecan, cisplatin, etoposide, or gemcitabine. Proc Amer Assoc Cancer Res 1998; 39: 527.
-
(1998)
Proc Amer Assoc Cancer Res
, vol.39
, pp. 527
-
-
Barrera, H.1
MacDonald, J.R.2
Hilsenbeck, S.3
Weitman, S.4
-
13
-
-
0002217967
-
Antitumor activity of MGI 114 against two human prostate tumor xenografts
-
Mangold G, MacDonald J, Von Hoff D, Weitman S. Antitumor activity of MGI 114 against two human prostate tumor xenografts. 10th NCI-EORTC Symposium Proceedings, 1998, p 37.
-
(1998)
10th NCI-EORTC Symposium Proceedings
, pp. 37
-
-
Mangold, G.1
MacDonald, J.2
Von Hoff, D.3
Weitman, S.4
-
14
-
-
0001103571
-
Evidence of synergistic antitumor activity with MGI 114 in combination with Irinotecan or 5-fluorouracil against a human colon tumor xenograft model
-
Marty J, MacDonald J, Mangold G, Weitman S, Von Hoff D. Evidence of synergistic antitumor activity with MGI 114 in combination with Irinotecan or 5-fluorouracil against a human colon tumor xenograft model. Proc Amer Assoc Cancer Res 1998; 39: 527.
-
(1998)
Proc Amer Assoc Cancer Res
, vol.39
, pp. 527
-
-
Marty, J.1
MacDonald, J.2
Mangold, G.3
Weitman, S.4
Von Hoff, D.5
-
15
-
-
0021955430
-
HL60/ascites tumor: A transplantable human tumor model for in vivo testing of differentiation inducers
-
Bogden AE, Cobb WR, Breitman TR, Wolpert-DeFilippes MK, DeLarco B, Vendetti JM, Plowman J, Shoemaker RH. HL60/ascites tumor: a transplantable human tumor model for in vivo testing of differentiation inducers. Proc Amer Assoc Cancer Res 1985; 26: 34.
-
(1985)
Proc Amer Assoc Cancer Res
, vol.26
, pp. 34
-
-
Bogden, A.E.1
Cobb, W.R.2
Breitman, T.R.3
Wolpert-DeFilippes, M.K.4
DeLarco, B.5
Vendetti, J.M.6
Plowman, J.7
Shoemaker, R.H.8
-
16
-
-
0023106388
-
Retinoid acid-induced monocytic differentiation of HL60/MRI, a cell lined derived from a transplantable HL60 tumor
-
Omasum M, Asemia J, Breitman TR. Retinoid acid-induced monocytic differentiation of HL60/MRI, a cell lined derived from a transplantable HL60 tumor. Cancer Res 1987; 47: 1434-1440.
-
(1987)
Cancer Res
, vol.47
, pp. 1434-1440
-
-
Omasum, M.1
Asemia, J.2
Breitman, T.R.3
-
17
-
-
0024213553
-
Changes in c-myc, c-f's, and N-ras proto-oncogene expression associated with retinoid acid-induced monocytic differentiation of human leukemia HL60/MRI cells
-
Omasum M, Breitman TR. Changes in c-myc, c-f's, and N-ras proto-oncogene expression associated with retinoid acid-induced monocytic differentiation of human leukemia HL60/MRI cells. Cancer Res 1988; 48: 6733-6738.
-
(1988)
Cancer Res
, vol.48
, pp. 6733-6738
-
-
Omasum, M.1
Breitman, T.R.2
-
18
-
-
0003030325
-
Applications of median-effects principle for the assessment of low-dose risk of carcinogens and for the quantitation of synergism and antagonism of chemotherapeutic agents
-
Harrap KR, Connors TA (eds). Academic Press: New York
-
Chou T-C, Talky P. Applications of median-effects principle for the assessment of low-dose risk of carcinogens and for the quantitation of synergism and antagonism of chemotherapeutic agents. In: Harrap KR, Connors TA (eds). New Avenues in Developmental Cancer Chemotherapy. Academic Press: New York, 1987, pp 37-64.
-
(1987)
New Avenues in Developmental Cancer Chemotherapy
, pp. 37-64
-
-
Chou, T.-C.1
Talky, P.2
-
19
-
-
0002658306
-
The median-effect principle and the combination index for quantification of synergism and antagonism
-
Chou T-C, Rideout DE (eds). Academic Press: New York
-
Chou T-C. The median-effect principle and the combination index for quantification of synergism and antagonism. In: Chou T-C, Rideout DE (eds). Synergism and Antagonism in Chemotherapy. Academic Press: New York, 1991, pp 61-102.
-
(1991)
Synergism and Antagonism in Chemotherapy
, pp. 61-102
-
-
Chou, T.-C.1
-
22
-
-
0030049896
-
Acylfulvenes, a new class of potent antitumor agents
-
McMorris TC, Kelner MJ, Wang W, Diaz MA, Estes LA, Taetle R. Acylfulvenes, a new class of potent antitumor agents. Experientia 1996; 52: 75-80.
-
(1996)
Experientia
, vol.52
, pp. 75-80
-
-
McMorris, T.C.1
Kelner, M.J.2
Wang, W.3
Diaz, M.A.4
Estes, L.A.5
Taetle, R.6
-
23
-
-
0029834306
-
(Hydroxymethyl)acylfulvene: An illudin derivative with superior antitumor properties
-
McMorris TC, Kelner MJ, Wang W, Yu J, Estes LA, Taetle R. (Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties. J Nat Prod 1996; 59: 896-899.
-
(1996)
J Nat Prod
, vol.59
, pp. 896-899
-
-
McMorris, T.C.1
Kelner, M.J.2
Wang, W.3
Yu, J.4
Estes, L.A.5
Taetle, R.6
-
24
-
-
0023146915
-
Use of nude mouse xenografts as preclinical drug screen: In vivo activity of established chemotherapeutic agents against melanomas and ovarian carcinoma xenografts
-
Taetle R, Rosen F, Abramson I, Bendetti J, Howell S. Use of nude mouse xenografts as preclinical drug screen: in vivo activity of established chemotherapeutic agents against melanomas and ovarian carcinoma xenografts. Cancer Treat Rep 1987; 71: 297-304.
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 297-304
-
-
Taetle, R.1
Rosen, F.2
Abramson, I.3
Bendetti, J.4
Howell, S.5
-
26
-
-
0001458215
-
Effects of more than one inhibitor
-
Webb JL (ed). Academic Press: New York
-
Webb JL. Effects of more than one inhibitor. In: Webb JL (ed). Enzymes and Metabolic Inhibitors, vol 1. Academic Press: New York, 1963, pp 66-79.
-
(1963)
Enzymes and Metabolic Inhibitors
, vol.1
, pp. 66-79
-
-
Webb, J.L.1
-
27
-
-
0029036955
-
The search for synergy: A critical review from a response surface perspective
-
Greco WR, Bravo G, Parsons JC. The search for synergy: a critical review from a response surface perspective. Pharmacol Rev 1995; 47: 331-385.
-
(1995)
Pharmacol Rev
, vol.47
, pp. 331-385
-
-
Greco, W.R.1
Bravo, G.2
Parsons, J.C.3
-
28
-
-
0028153260
-
Computerized quantitation of synergism and antagonism of Taxol, Topotecan, and Cisplatin against human teratocarcinoma cell growth: A rational approach to clinical protocol design
-
Chou T-C, Motzer JR, Tong Y, Bosl GJ. Computerized quantitation of synergism and antagonism of Taxol, Topotecan, and Cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J Natl Cancer Inst 1994; 86: 1517-1523.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1517-1523
-
-
Chou, T.-C.1
Motzer, J.R.2
Tong, Y.3
Bosl, G.J.4
-
29
-
-
0029945885
-
Cytotoxic effects of Topotecan combined with various anticancer agents in human cell lines
-
Kaufman SH, Peerebom D, Buckwalter CA, Svingen PA, Grochow LB, Donehower RC, Rowinsky EK. Cytotoxic effects of Topotecan combined with various anticancer agents in human cell lines. J Natl Cancer Inst 1996; 88: 734-741.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 734-741
-
-
Kaufman, S.H.1
Peerebom, D.2
Buckwalter, C.A.3
Svingen, P.A.4
Grochow, L.B.5
Donehower, R.C.6
Rowinsky, E.K.7
-
30
-
-
0030718488
-
Effect on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene, 6-hydroxymethylacylfulvene (HMAF, MGI 114)
-
Woynarowski JM, Napier C, Koester SK, Chen S-F, Troyer D, Chapman W, MacDonald JR. Effect on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene, 6-hydroxymethylacylfulvene (HMAF, MGI 114). Biochem Pharmacol 1997; 54: 1181-1193.
-
(1997)
Biochem Pharmacol
, vol.54
, pp. 1181-1193
-
-
Woynarowski, J.M.1
Napier, C.2
Koester, S.K.3
Chen, S.-F.4
Troyer, D.5
Chapman, W.6
MacDonald, J.R.7
-
31
-
-
0342284955
-
In vitro and in vivo interactions between cisplatin and topotecan
-
Romanelli S, Perego P, Pratesi G, Carenini N, Tortoreto M, Zunino F. In vitro and in vivo interactions between cisplatin and topotecan. Cancer Chemother Pharmacol 1998; 41: 185-390.
-
(1998)
Cancer Chemother Pharmacol
, vol.41
, pp. 185-390
-
-
Romanelli, S.1
Perego, P.2
Pratesi, G.3
Carenini, N.4
Tortoreto, M.5
Zunino, F.6
-
32
-
-
0030805565
-
When helicase and topoisomerase meet!
-
Duget M. When helicase and topoisomerase meet! J Cell Sci 1997; 110: 1345-1350.
-
(1997)
J Cell Sci
, vol.110
, pp. 1345-1350
-
-
Duget, M.1
-
33
-
-
0342284938
-
SKF 104864 (Topotecan): Preclinical studies of a new topoisomerase inhibitor
-
Burris H, Kuhn J, Johnson K, Von Hoff D. SKF 104864 (Topotecan): preclinical studies of a new topoisomerase inhibitor. Proc Am Soc Clin Oncol 1990; 11: 216.
-
(1990)
Proc Am Soc Clin Oncol
, vol.11
, pp. 216
-
-
Burris, H.1
Kuhn, J.2
Johnson, K.3
Von Hoff, D.4
-
34
-
-
0010263172
-
Phase I and pharmacologic study of topotecan (SKF 104864): A novel topoisomerase I inhibitor
-
Rowinsky E, Grochow L, Hendritks C. Phase I and pharmacologic study of topotecan (SKF 104864): a novel topoisomerase I inhibitor. Proc Am Soc Clin Oncol 1991; 10: 93.
-
(1991)
Proc Am Soc Clin Oncol
, vol.10
, pp. 93
-
-
Rowinsky, E.1
Grochow, L.2
Hendritks, C.3
-
35
-
-
0343590059
-
A phase II trial of MGI 114 in patients with hormone-refractory prostate cancer
-
Senser NN, Rakvica R, Chao H, Smith S. A phase II trial of MGI 114 in patients with hormone-refractory prostate cancer. Proc Am Soc Clin Oncol 1999; 18: 321A.
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Senser, N.N.1
Rakvica, R.2
Chao, H.3
Smith, S.4
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