Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: Biochemical, electrophysiological, and behavioral characterization

Journal of Pharmacology and Experimental Therapeutics

Volumn 292, Issue 1, 2000, Pages 215-227

  Snell, Lawrence D ^a   Claffey, David J ^b   Ruth, James A ^b   Valenzuela, C Fernando ^a   Cardoso, Rita ^a   Wang, Zejun ^a   Levinson, Simon R ^a   Sather, William A ^a   Williamson, Anna V ^a   Ingersoll, Nan C ^a   Ovchinnikova, Larissa ^a   Bhave, Sanjiv V ^a   Hoffman, Paula L ^a   Tabakoff, Boris ^a,c  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N,N (DIPHENYL) 4 UREIDO 5,7 DICHLORO 2 CARBOXY QUINOLINE; N,N (DIPHENYL) 4 UREIDO 5,7 DICHLORO 2 CARBOXYL METHYL ESTER; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ARTICLE; COMPETITIVE INHIBITION; DRUG EFFECT; DRUG PROTEIN BINDING; MALE; MOLECULAR RECOGNITION; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SEDATION; SEIZURE;

ANIMALS; ANTI-ANXIETY AGENTS; ATAXIA; BEHAVIOR, ANIMAL; BINDING SITES; BINDING, COMPETITIVE; CELLS, CULTURED; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLYCINE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; NEURONS; OOCYTES; PHENYLUREA COMPOUNDS; PROTEIN BINDING; QUINOLINES; RATS; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SOUND; STRYCHNINE; SUBSTANCE WITHDRAWAL SYNDROME; XENOPUS;

EID: 0033957729     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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