Insulin sensitivity and secretion influence the relationship between growth hormone-binding-protein and leptin

Clinical Endocrinology

Volumn 52, Issue 2, 2000, Pages 159-164

  Fernandez Real, José Manuel ^a   Granada, Maria Luisa ^b   Ruzafa, Ana ^b   Casamitjana, Roser ^b   Ricart, Wifredo ^b  

^a HOSPITAL JOSEP TRUETA   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE BINDING PROTEIN; INSULIN; LEPTIN;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; FEMALE; GLUCOSE INTOLERANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE PROTEIN COMPLEX; HUMAN; HUMAN CELL; HUMAN TISSUE; IMPEDANCE; INSULIN RELEASE; INSULIN SENSITIVITY; MALE; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADULT; BODY CONSTITUTION; CARRIER PROTEINS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; LEPTIN; LINEAR MODELS; MALE; OBESITY; PROSPECTIVE STUDIES;

EID: 0033955261     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2000.00907.x     Document Type: Article

References (29)

1. Argente, J., Caballo, N., Barrios, V., Muñoz, M.T., Pozo, J., Chowen, J.A., Morande, G. & Hernández, M. (1997) Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: effect of short- and long-term weight recuperation. Journal of Clinical Endocrinology and Metabolism, 82, 2084-2092.
2. Barnard, R., Chan, F.Y. & McIntyre, H.D. (1997) Growth hormone-binding protein in normal and pathologic gestation: correlations with maternal diabetes and fetal growth. Journal of Clinical Endocrinology and Metabolism, 82, 1879-1884.
3. Baumann, G. & Mercado, M. (1993) Growth hormone-binding proteins in plasma. Nutrition, 9, 546-553.
4. Bergman, R.N., Prager, R., Volund, A. & Olefsky, J.M. (1987) Equivalence of the insulin sensitivity index in man derived by the minimal model method and euglycaemic glucose clamp. Journal of Clinical Investigation, 79, 790-800.
5. Baxter, R.C. & Turtle, J.R. (1978) Regulation of hepatic growth hormone receptors by insulin. Biochemical and Biophysical Research Commununications, 84, 350-357.
6. Baxter, R.C., Brown, A.S. & Turtle, J.R. (1980) Association between serum insulin, serum somatomedin and liver receptors for human growth hormone in streptozotocin diabetes. Hormone and Metabolism Research, 12, 377-381.
7. Casper, R.C. (1996) Carbohydrate metabolism and its regulatory hormones in anorexia nervosa. Psychiatry Research, 62, 85-96.
8. Fernández-Real, J.M., Casamitjana, R. & Ricart, W. (1998) Leptin is involved in gender-related differences in insulin sensititivity. Clinical Endocrinology, 49, 505-512.
9. Ferrannini, E. & Mari, A. (1998) How to measure insulin sensitivity. Journal of Hypertension, 16, 895-906.
10. Florkowski, C.M., Barnard, R., Livesey, J.H., Veveris, T., Espiner, E.A. & Donald, R.A. (1999) Growth hormone binding protein correlates strongly with leptin and percentage body afat in GH-deficient adults, is increased by GH replacement but does not predict IGF-I response. Growth Hormone and IGF Research, 9, 35-40.
11. Hanaire-Broutin, H., Sallerin-Caute, B., Poncet, M.F., Tauber, M., Bastide, R., Rosenfeld, R. & Tauber, J.P. (1996) Insulin therapy and GH-IGF-I axis disorders in diabetes: impact of glycaemic control and hepatic insulinization. Diabetes and Metabolism, 22, 245-250.
12. Hochberg, Z., Hertz, P., Colin, V. et al. (1992) The distal axis of growth hormone (GH) in nutritional disorders: GH-binding protein, insulin-like growth factor-I (IGF-I), and IGF-I receptors in obesity and anorexia nervosa. Metabolism, 41, 106-112.
13. Holl, R.W., Snehotta, R., Siegler, B., Scherbaum, W. & Heinze, E. (1991) Binding protein for human growth hormone: effects of age and weight. Hormone Research, 35, 190-197.
14. Katsuki, A., Sumida, Y., Murashima, S. et al. (1996) Acute and chronic regulation of serum sex hormone-binding globulin levels by plasma insulin concentrations in male with noninsulin-dependent diabetes mellitus patients. Journal of Clinical Endocrinology and Metabolism, 81, 2515-2519.
15. Kennedy, A., Gettys, T.W., Watson, P., Wallace, P., Ganaway, E., Pan, Q. & Garvey, W.T. (1997) The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure. Journal of Clinical Endocrinology and Metabolism, 82, 1293-1300.
16. Ketelslegers, J.M., Maiter, D., Maes, M., Underwood, L.E. & Thissen, J.P. (1996) Nutritional regulation of the growth hormone and insulin-like growth factor-binding proteins. Hormone Research, 45, 252-257.
17. Kratzsch, J., Dehmel, B., Pulzer, F., Keller, E., Englaro, P., Blum, W.F. & Wabitsch, M. (1997) Increased serum GHBP levels in obese pubertal children and adolescents: relationship to body composition, leptin and indicators of metabolic disturbances. International Journal of Obesity and Related Metabolic Disorders, 21, 1130-1136.
18. Larsson, H., Elmstahl, S. & Ahrén, B. (1996) Plasma leptin levels correlate to islet function independently of body fat in postmenopausal women. Diabetes, 45, 1580-1584.
19. Lesniak, M.A., Roth, I., Gorden, P. & Gavin, J.R. (1973) Human growth hormone radioreceptor assay using cultured human lymphocytes. Nature, 241, 20-22.
20. Llopis, M.A., Granada, M.L., Audí, L., Sanmartí, A., Bel, J., Sánchez-Planell, L., Formiguera, X., Marin, F. & Corominas, A. (1997) Analytical performance and clinical usefulness of two binding assays for growth hormone binding protein (GHBP) measurement: high performance liquid chromatography (HPLC)-gel filtration and dextrin-coated charcoal adsorption. Clinica Chimica Acta, 267, 167-181.
21. Llopis, M.A., Granada, M.L., Cuatrecasas, G., Formiguera, X., Sánchez-Planell, L., Sanmartí, A., Alastrué, A., Rull, M., Corominas, A. & Foz, M. (1998) Growth hormone-binding protein directly depends on serum leptin levels in adults with different nutritional status. Journal of Clinical Endocrinology and Metabolism, 83, 2006-2011.
22. Martha, P.M., Rogol, A.D., Blizzard, R.M., Shaw, M.A. & Baumann, G. (1991) Growth hormone-binding protein activity is inversely related to 24-hour growth hormone release in normal boys. Journal of Clinical Endocrinology and Metabolism, 73, 175-181.
23. Nam, S.Y., Kim, K.R., Song, Y.D., Lim, S.K., Lee, H.C. & Huh, K.B. (1999) GH-binding protein in obese men with varying glucose tolerance: relationship to body fat distribution, insulin secretion and the GH-IGF-I axis. European Journal of Endocrinology, 140, 159-163.
24. National Diabetes Data Group. (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes, 28, 1039-1057.
25. Rasmussen, M.H., Ho, K.Y.K., Kjems, L. & Hilsted, J. (1996) Serum growth hormone-binding protein in obesity: effect of short-term, very low caloric diet and diet-induced weight loss. Journal of Clinical Endocrinology and Metabolism, 81, 1519-1524.
26. Roelen, C.A., Koppeschaar, H.P.D.E., Vries, W.R., Snel, Y.E.M., Doerga, M.E., Zelissen, P.M.J., Thijssen, J.H.H. & Blankenstein, M.A. (1997) Visceral adipose tissue is associated with circulating high affinity growth hormone binding protein. Journal of Clinical Endocrinology and Metabolism, 82, 760-764.
27. Tar, A., Hocquette, J.F., Souberbielle, J.C., Clop, J.P., Brauner, R. & Postel-Vinay, M.C. (1990) Evaluation of the growth hormone-binding proteins in human plasma using high pressure liquid chromatography gel filtration. Journal of Clinical Endocrinology and Metabolism, 71, 1202-1207.
28. Yasunaga, T., Furukawa, S., Katsumata, N., Horikawa, R., Tanaka, T., Tanae, A. & Hibi, I. (1998) Nutrition related hormonal changes in obese children. Endocrine Journal, 45, 221-227.
29. Yki-Jarvinen, H., Makimattila, S., Utriainen, T. & Rutanen, E.M. (1995) Portal insulin concentrations rather than insulin sensitivity regulate serum sex hormone-binding globulin and insulin-like growth factor binding protein 1 in vivo. Journal of Clinical Endocrinology and Metabolism, 80, 3227-3232.