Angiogenesis inhibitor, TNP-470, suppresses growth of peritoneal disseminating foci

Hepato-Gastroenterology

Volumn 47, Issue 31, 2000, Pages 298-302

  Yoshikawa, Takaki ^a   Yanoma, Syunsuke ^b   Tsuburaya, Akira ^b   Kobayashi, Osamu ^b   Sairenji, Motonori ^b   Motohashi, Hisahiko ^b   Noguchi, Yoshikazu ^b  

^a KANAGAWA CANCER CENTER   (Japan)

^b NONE

Author keywords

Angiogenesis; Gastric cancer; MKN 45; Peritoneal dissemination; TNP 470

Indexed keywords

FUMAGILLOL CHLOROACETYLCARBAMATE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SURVIVAL TIME; TUMOR GROWTH;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL DIVISION; CYCLOHEXANES; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PERITONEAL NEOPLASMS; SESQUITERPENES; STATISTICS, NONPARAMETRIC; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0033954398     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. 1 Parkin DM, Laara E, Muir CS: Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1988; 41:184-197.
2. 2 Koga S, Kishimoto H, Tanaka K, Kawaguchi H: Clinical and pathologic evaluation of patients with recurrence of gastric cancer more than five years postoperatively. Am J Surg 1978; 136:317-321.
3. 3 Jaehne J, Meyer HJ, Soudah B, Maschek H, Pichlmayr R: Peritoneal lavage in gastric carcinoma. Dig Surg 1989; 6:26-28.
4. 4 Dupont JB Jr, Lee JR, Burton GR, Cohn I Jr: Adenocarcinoma of the stomach: review of 1497 cases. Cancer 1987; 41:941-947.
5. 5 Kaibara N, Iitsuka Y, Kimura A, Kobayashi Y, Hirooka Y, Nishidoi H, Koga S: Relationships between area of serosal invasion and prognosis in patients with gastric carcinoma. Cancer 1987; 60:136-139.
6. 6 Boku T, Nakane Y, Minoura T, Takada H, Yamamura M, Hioki K, Yamamoto M: Prognostic significance of serosal invasion and free intraperitoneal cancer cells in gastric cancer. Br J Surg 1990; 77:436-439.
7. 7 Hart TR: 'Seed and soil' revisited: mechanisms of site-specific metastasis. Cancer Metastasis Rev 1982; 1:5-16.
8. 8 Fidler IJ, Balch CM: The biology of cancer metastasis and implications for therapy. Curr Probl Surg 1987; 24:129-209.
9. 9 Folkman J: Tumor angiogenesis. Advanc Cancer Res 1985; 43:175-203.
10. 10 Folkman J: Tumor angiogenesis: therapeutic implications. New Engl J Med 1971; 285:1182-1186.
11. 11 Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med 1995; 1:27-31.
12. 12 Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J: Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature 1990; 348:555-557.
13. 13 Kusaka M, Sudo K, Fujita T, Marui S, Itoh F, Ingber D, Folkman J: Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem Biophys Res Commun 1991; 174:1070-1076.
14. 14 Castronovo V and Belotti D: TNP-470 (AGM-1470): mechanisms of action and early clinical development. Eur J Cancer 1996; 32:2520-2527.
15. 15 Konno H, Tanaka T, Matsuda I, Kanai T, Maruo Y, Noshino N, Nakamura S, Baba S: Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, and mitomycin on the growth and liver metastasis of human colon cancer. Int J Cancer 1995; 61:268-271.
16. 16 Ahmed MH, Konno H, Nahar L, Tanaka T, Naito Y, Nakamura S, Baba S: The angiogenesis inhibitor TNP-470 (AGM-1470) improves long-term survival of rats with liver metastasis. J Surg Res 1996;64: 35-41.
17. 17 Kanai T, Konno H, Tanaka T, Matsumoto K, Baba M, Nakamura S, Baba S: Effect of angiogenesis inhibitor TNP-470 on the progression of human gastric cancer xenotransplanted into nude mice. Int J Cancer 1997; 71:838-841.
18. 18 Ahmed MH, Arai T, Konnno H, Nahar L, Tanaka T, Izumiyama N, Takubo K, Nakamura S, Baba S: Regression of metastatic liver tumors in rats treated with angiogenesis inhibitor TNP-470: Occurrence of apoptosis and necrosis. Jpn J Cancer Res 1997; 88:977-981.
19. 19 Hagiwara A, Takahashi T, Kojima O, Sawai K, Yamaguchi T, Yamane T, Taniguchi H, Kitamura K, Noguchi A, Seiki K, Sakakura C: Prophylaxis with carbon-absorbed mitomycin against recurrence of gastric cancer. Lancet 1992; 339:629-631.
20. 20 Yonemura Y, Fujimura T, Nishimura G, Falla R, Sawa T, Katayama K, Tsugawa K, Fushida S, Miyazaki I, Tanaka M, Endou Y, Sasaki T: Effects of intraoperative chemohyperthermia in patients with gastric cancer with peritoneal dissemination. Surgery 1996; 119:437-444.
21. 21 Yonemura Y, Fujimura T, Fushida S, Fujita H, Bando E, Taniguchi K, Nishimura K, Miwa K, Ohyama S, Sugiyama K, Sasaki T, Endo Y: Peritonectomy as a treatment modality for patients with peritoneal dissemination from gastric cancer. In: Nakajima T, Yamaguchi T (Eds.). Multimodality therapy for gastric cancer. Tokyo: Springer-Verlag, 1999; pp. 71-80.
22. 22 Ynagi K and Oshima N: Angiogenic vascular growth in the rat peritoneal disseminated tumor model. Microvascular Res 1996; 51:15-28.
23. 23 Tsujimoto H, Hagiwara A, Osaki K, Ohyama T, Sakakibara T, Sakuyama A, Ohgaki M, Imanishi T, Watanabe N, Yamazaki J: Therapeutic effects of the angiogenesis inhibitor TNP-470 against carcinomatous peritonitis in mice. Anti-Cancer Drugs, 1995; 6:438-442.
24. 24 Kato T, Sato K, Kakinoma H, Matsuda Y: Enhanced suppression of tumor growth by combination of angiogenesis inhibitor O-(chloroacetyl-carbamoyl) fumagillol (TNP-470) and cytotoxic agents in mice. Cancer Res 1994; 54:5143-5147.
25. 25 Wilson JT, Penar PL: The effect of AGM-1470 in an improved intracranial 9L gliosarcoma rat model. Neurol Res 1994; 16:121-124.