Effect of angiogenesis inhibitor TNP-470 on the progression of human gastric cancer xenotransplanted into nude mice

International Journal of Cancer

Volumn 71, Issue 5, 1997, Pages 838-841

  Kanak, Toshikazu ^a   Konno, Hiroyuki ^a   Tanaka, Tatsuo ^a   Matsumoto, Keigo ^a   Baba, Megumi ^a   Nakamura, Satoshi ^a   Baba, Shozo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER METASTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH CARCINOMA; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR GROWTH; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BODY WEIGHT; CELL DIVISION; CYCLOHEXANES; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PERITONEAL NEOPLASMS; SESQUITERPENES; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0030927584     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970529)71:5<838::AID-IJC23>3.0.CO;2-2     Document Type: Article

References (21)

1. AHMED, M.H., KONNO. H., NAHAR. L., TANAKA. T., NAITO, Y., NAKAMURA, S. and BABA, S., The angiogenesis inhibitorTNP-470 (AGM-1470) improves long-term survival of rats with liver metastasis. J. surg. Res., 64, 35-41 (1996).
2. BOKU, T., NAKANE, Y., MINOURA, T., TAKADA, H., YAMAMURA, M., HIOKI, K. and YAMAMOTO, M., Prognostic significance of serosal invasion and free intraperitoneal cancer cells in gastric cancer. Brit. J. Surg., 77, 436-439 (1990).
3. DVORAK, H.F., NAGY, J.A., DVORAK, J.T. and DVORAK, A.M., Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Amer. J. Pathol., 133, 95-109 (1988).
4. FIDLER, I.J. and BALCH, C.M., The biology of cancer metastasis and implications for therapy. Curr. Probl. Surg., 24, 129-209 (1987).
5. FOLKMAN, J., Tumor aneiosenesis: therapeutic implications. New Engl. J. Med., 285, 1182-1186 (1971).
6. FOLKMAN, J., Tumor angiogenesis. Advanc. Cancer Res., 43, 175-203 (1985).
7. FU, X., RESTERMAN, J.M., MONOSOV, A. and HUFFMAN, R.M., Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. Proc. mat. Acad. Sci. (Wash.), 88, 9345-9349 (1991).
8. FURUKAWA, T., Fu, X., KUBOTA, T., WATANABE, M., KITAJIMA, M. and HUFFMAN, R.M., Nude mouse metastatic models of human stomach cancer constructed using orthotopic implantation of histologically intact tissue. Cancer Res., 53, 1204-1208 (1993).
9. INGBER, D., FUJITA. T., KISHIMOTO, S., SUDO, K., KANAMARU, T., BREM, H. and FOLKMAN, J., Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature (Lond.), 348, 555-557 (1990).
10. KATO, T., SATO, K., KAKINUMA, H. and MATSUDA, Y., Enhanced suppression of tumor growth by combination of angiogenesis inhibitor O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and cytotoxic agents in mice. Cancer Res., 54, 5143-5147 (1994).
11. KIM, K.J., LI, B., WINER, J., ARMANINI, M., GILLETT, N., PHILLIPS, H.S. and FERRARA, N., Inhibition of vascular endothelial-growth-factor-induced anaiogenesis suppresses tumour arowth in vivo. Nature (Lond.), 362, 841-844 (1993).
12. KONNO, H., TANAKA, T., MATSUDA, I., KANAI, T., MARUO, Y., NISHINO, N., NAKAMURA, S. and BABA, S., Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, and mitomycin C on the growth and liver metastasis of human colon cancer. Int. J. Cancer, 61, 268-271 (1995).
13. KOOP, S., MACDONALD, I.C., LUZZI, K., SCHMIDT, E.E., MORRIS, V.L., GRATTAN, M., KHOKHA, R., CHAMBERS, A.F. and GROOM, A.C., Fate of melanoma cells entering the microcirculation: over 80% survive and extravasate. Cancer Res., 55, 2520-2523 (1995).
14. KUO, T.S., KUBOTA, T., WATANABE, M., FURUKAWA, T., TERAMOTO, T., ISHIBIKI, K., KITAJIMA, M. and HOFFMAN, R.M., Early resection of primary orthotopically growing human colon tumor in nude mouse prevents liver metastasis: further evidence for patient-like hematogenous metastatic route. Anticancer Res., 13, 293-298 (1993).
15. KUSAKA, M., SUDO, K., FUJITA, T., MARUI, S., ITOH, F., INOBER, D. and FOLKMAN, J., Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem. biophys. Res. Comm., 174, 1070-1076 (1991).
16. POSTE, G. and FIDLER, I.J., The pathogenesis of cancer metastasis. Nature (Lond.).283, 139-146 (1980).
17. SINGH, R.K., BUCANA, C.D., GUTMAN, M., FAN, D., WILSON, M.R. and FIDLER, I.J., Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells. Amer. J. Pathol., 145, 365-374 (1994).
18. TANAKA, T., KONNO, H., MATSUDA, I., NAKAMURA, S. and BABA, S., Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470. Cancer Res., 55, 836-839 (1995).
19. TSUJIMOTO, H. and 13 OTHERS. Therapeutic effects of the angiogenesis inhibitor TNP-470 against carcinomatous peritonitis in mice. Anti-Cancer Drugs, 6, 438-442 (1995).
20. WILMANNS, C., FAN, D., O'BRIAN, C.A., BUCANA, C.D. and FIDLER, I.J., Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil. Int. J. Cancer, 52, 98-104 (1992).
21. YANASE, T., TAMURA, M., FUJITA, K., KODAMA, S. and TANAKA, K., Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo. Cancer Res., 53, 2566-2570 (1993).