Differential effects of nicotine and aging on splenocyte proliferation and the production of Th1- versus Th2-type cytokines

Proceedings of the Society for Experimental Biology and Medicine

Volumn 224, Issue 3, 2000, Pages 141-146

  Hallquist, Nora ^a   Hakki, Amal ^a   Wecker, Lynn ^a   Friedman, Herman ^a   Pross, Susan ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 10; NICOTINE; NICOTINIC RECEPTOR;

AGE; AGING; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; IMMUNOCOMPETENCE; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

EID: 0033948493     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1373.2000.22412.x     Document Type: Article

References (40)

1. Bhandari N, Sylvester SL, Rogotti NA. Source Book of Substance Abuse and Addiction. Baltimore, MD: Williams & Wilkins, pp140-142, 1996.
2. Heusch WL, Maneckjee R. Signaling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 19:551-556, 1998.
3. Sopori ML, Kozak W. Immunomodulatory effects of cigarette smoke. J Neuroimmunol 83:148-156, 1998.
4. Li JS, Peat JK, Xuan W, Berry G. Meta-analysis on the association between environmental tobacco smoke (ETS) exposure and the prevalence of lower respiratory tract infection in early childhood. Pediatr Pulmonol 27:5-13, 1999.
5. Berglund DJ, Abbey DE, Lebowitz MD, Knutsen SF, McDonnell WF. Respiratory symptoms and pulmonary function in an elderly nonsmoking population [see comments]. Chest 115:49-59, 1999.
6. Willers S, Svenonius E, Skarping G. Passive smoking and childhood asthma: Urinary cotinine levels in children with asthma and in referents. Allergy 46:330-334, 1991.
7. De Swert LF. Risk factors for allergy. Eur J Pediatr 158:89-94, 1999.
8. Johnson BE. Tobacco and lung cancer. Prim Care 25:279-291, 1998.
9. Hecht SS. Tobacco and cancer: Approaches using carcinogen biomarkers and chemoprevention. Ann N Y Acad Sci 833:91-111, 1997.
10. Sopori ML, Kozak W, Savage SM, Geng Y, Soszynski D, Kluger MJ, Perryman EK, Snow GE. Effect of nicotine on the immune system: Possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology 23:189-204, 1998.
11. Mellon RD, Bayer BM. The effects of morphine, nicotine, and epibatidine on lymphocyte activity and hypothalamic-pituitary-adrenal axis responses. J Pharmacol Exp Ther 288:635-642, 1999.
12. Hiemke C, Stolp M, Reuss S, Wevers A, Reinhardt S, Maelicke A, Schlegel S, Schroder H. Expression of α subunit genes of nicotinic acetylcholine receptors in human lymphocytes. Neurosci Lett 214:171-174, 1996.
13. Mizuno Y, Dosch HM, Gelfand EW. Carbamycholine modulation of E-rosette formation: Identification of nicotinic acetylcholine receptors on a subpopulation of human T lymphocytes. J Clin Immunol 2:303-308, 1982.
14. Benowitz N. Pharmacology of nicotine: Addiction and therapeutics. Annu Rev Pharmacol Toxicol 36:597-613, 1996.
15. Sindermann J, Kruse A, Frercks HJ, Schutz RM, Kirchner H. Investigations of the lymphokine system in elderly individuals. Mech Ageing Dev 70:149-159, 1993.
16. Kubo M, Cinader B. Polymorphism of age-related changes in interleukin (IL) production: Differential changes of T-helper subpopulations, synthesizing IL-2, IL-3, and IL-4. Eur J Immunol 20:1289-1296, 1990.
17. Patel HR, Miller RA. Age-associated changes in mitogen-induced protein phosphorylation in murine T lymphocytes. Eur J Immunol 22:253-260, 1992.
18. Timiras PS. Physiological Basis of Aging and Geriatrics. Boca Raton, FL: CRC Press, 1994.
19. Kurihara S. Effect of age on blood pressure response to cigarette smoking. Cardiology 86:102-107, 1995.
20. Risser NL. Prevention of lung cancer: The key is to stop smoking. Semin Oncol Nurs 12:260-269, 1996.
21. Urakawa N, Nagata T, Kudo K, Kimura K, Imamura T. Simultaneous determination of nicotine and cotinine in various human tissues using capillary gas chromatography/mass spectrometry. Int J Legal Med 106:232-236, 1994.
22. Prokopczyk B, Cox JE, Hoffmann D, Waggoner SE. Identification of tobacco-specific carcinogen in the cervical mucus of smokers and nonsmokers. J Natl Cancer Inst 89:868-873, 1997.
23. Rowell PP, Hurst HE, Marlowe C, Bennett BD. Oral administration of nicotine: Its uptake and distribution after chronic administration to mice. J Pharmacol Meth 9:249-261, 1983.
24. Sastry BV, Chance MB, Singh G, Horn JL, Janson VE. Distribution and retention of nicotine and its metabolite, cotinine, in the rat as a function of time. Pharmacology 50:128-136, 1995.
25. Sharon N. Lectin receptors as lymphocyte surface markers. Adv Immunol 34:213-298, 1983.
26. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev 9:532-562, 1996.
27. 4 memory T cells differing in P- glycoprotein expression: Effects of aging. J Gerontol A Biol Sci Med Sci 52:B137-B145, 1997.
28. 4+ T cells from young and old mice. J Immunol 150:3602-3614, 1993.
29. Kurashima C, Utsuyama M. Age-related changes of cytokine production by murine helper T-cell subpopulations. Pathobiology 65:155-162, 1997.
30. Sher ME, Bank S, Greenberg R, Sardinha TC, Weissman S, Bailey B, Gilliland R, Wexner SD. The influence of cigarette smoking on cytokine levels in patients with inflammatory bowel disease. Inflamm Bowel Dis 5:73-78, 1999.
31. Russel MG, Volovics A, Schoon EJ, van Wijlick EH, Logan RF, Shivananda S, Stockbrugger RW. Inflammatory bowel disease: Is there any relation between smoking status and disease presentation? European Collaborative IBD Study Group. Inflamm Bowel Dis 4:182-186, 1998.
32. Baron JA. Beneficial effects of nicotine and cigarette smoking: The real, the possible, and the spurious. Br Med Bull 52:58-73, 1996.
33. Madretsma S, Wolters LM, van Dijk JP, Tak CJ, Feyerabend C, Wilson JH, Zijlstra FJ. In vivo effect of nicotine on cytokine production by human nonadherent mononuclear cells. Eur J Gastroenterol Hepatol 8:1017-1020, 1996.
34. Parronchi P, Romagnani P, Annunziato F, Sampognaro S, Becchio A, Giannarini L, Maggi E, Pupilli C, Tonelli F, Romagnani S. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol 150:823-832, 1997.
35. Le Cam L, Lagier B, Bousquet J, Pene J. Nicotine does not modulate IL-4 and interferon-γ release from peripheral blood mononuclear cells and T-cell clones activated by phorbol myristate acetate and calcium ionophore. Int Arch Allergy Immunol 111:372-375, 1996.
36. Davies BD, Hoss W, Lin JP, Lionetti F. Evidence for a noncholinergic nicotine receptor on human phagocytic leukocytes. Mol Cell Biochem 44:23-31, 1982.
37. Adem A, Nordberg A, Bucht G, Winblad B. Extraneural cholinergic markers in Alzheimer's and Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry 10:247-257, 1986.
38. Sato KZ, Fujii T, Watanabe Y, Yamada S, Ando T, Kazuko F, Kawashima K. Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines. Neurosci Lett 266:17-20, 1999.
39. Geng Y, Savage SM, Johnson LJ, Seagrave J, Sopori ML. Effects of nicotine on the immune response. I. Chronic exposure to nicotine impairs antigen receptor-mediated signal transduction in lymphocytes. Toxicol Appl Pharmacol 135:268-278, 1995.
40. 2+ concentration in human lymphocytes. Neuroimmunomodulation 3:247-253, 1996.