Nicotine does not modulate il-4 and interferon-γ release from peripheral blood mononuclear cells and t cell clones activated by phorbol myristate acetate and calcium lonophore

International Archives of Allergy and Immunology

Volumn 111, Issue 4, 1996, Pages 372-375

  Le Cam, Laurent ^a   Lagier, Béatrice ^a   Bousquet, Jean ^a   Pène, Jérôme ^a  

^a HÔPITAL ARNAUD DE VILLENEUVE   (France)

Author keywords

IgE; Interferon ; Interleukin 4; Nicotine

Indexed keywords

CALCIUM IONOPHORE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; NICOTINE; PHORBOL 13 ACETATE 12 MYRISTATE; TOBACCO SMOKE;

ALLERGY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; LYMPHOCYTE CLONE; MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; SMOKING; SUPERNATANT; T LYMPHOCYTE;

CALCIMYCIN; CARCINOGENS; CLONE CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-4; IONOPHORES; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; NICOTINE; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE;

EID: 0029837630     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237395     Document Type: Article

References (18)

1. Johnson JD, llouchcns DP, Kluwc WM, Craig DK, Fishcr GL: Effects of mainstream and environmental tobacco smoke on the immune system in animals and humans: A review, Crit Rev Toxicol 1990;20:369-395.
2. Riedel F, Niisslein T, Riischoff J, Ricgcl C: Tobacco smoke enhances allergic bronchial sensitization in the guinea pig, Pediatr Allergy Immunol 1990;1:26-33.
3. Venables KM, Upton JL, Hawkins ER, Tee RD, Longbottom JL, Newman-Taylor AJ: Smoking, atopy, and laboratory animal allergy, Br J Ind Med 1988;45:667-671.
4. Tagcr IB: Passive smoking - bronchial responsiveness and atopy, Am Rev Respir Dis 1988; 138:507-509.
5. Martinez FD, Antognoni G, Macri F, Bonci E, Midulla F, De Castro G, Ronchetti R: Parental smoking enhances bronchial responsiveness in nine-year-old children, Am Rev Respir Dis 1988;138:518-523.
6. Byron KA, Varigos GA, Wootton AM: IL-4 production is increased in cigarette smokers, Clin Exp Immunol 1994;95:333-336.
7. Benowitz NL: Clinical pharmacology of nicotine, Annu Rev Med 1986;37:21- 32.
8. Menard L, Rola-Pleszczynski M: Nicotine induces T-supprcssor cells: Modulation by the nicotinic antagonist D-tubocurarine and myasthenic serum, Clin Immunol Immunopathol 1987;44:107-113.
9. Fischer A, Konig W: Modulation of in vitro immunoglobulin synthesis of human peripheral blood mononuclear cells by nicotine and coti-nine, Clin Invest 1994;72:225-232.
10. Pène J, Roussct F, Brière F, Chretien I, Bonne-joy JY, Spits H, Yokota T, Arai N, Arai KI, Ban-chereau J, Dc Vries JE: IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2, Proc Natl Acad Sci USA 1988;85:6880-6884.
11. Romagnani S: Human TH1 and TH2 subsets: Doubt no more, Immunol Today 1991; 12:256-257.
12. Pène J, Rivier A, Lagier B, Becker WM, Michel FB, Bousquct J: Differences in IL-4 release by PBMC are related with heterogeneity of atopy, Immunology 1994;81:58-64.
13. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchicri G, Romagnani S: Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 The I-specific immune responses and inhibits the development of IL-4-producing Th cells, J Exp Med 1993;177:1199-1204.
14. Pènc J, Lagier B, Rivier A, Chanez P, Vendrcll JP, Bousquet J: Phenotype of T cell clones obtained from bronchial biopsies and peripheral blood from three asthmatics, Cell Biol Int 1993; 17:353-357.
15. Morcvra AE, Lacy CR, Wilson AC, Kumar A, KostisJB: Arterial blood nicotine concentration and coronary' vasoconstrictive effect of low-nic-otine cigarette smoking, Am Heart J 1992; 124: 392-397.
16. Mundal HH, lljemdahl P, Gjesdal K: Acute effects of low dose nicotine gum on platelet function in non-smoking hypertensive and normo-tensivs men, Eur J Clin Pharmacol I995;47: 411-416.
17. Klemsdal TO, Gjesdal K, Zahlsen K: Physical exercise increases plasma concentrations of nicotine during treatment with a nicotine patch, Br J Clin Pharmacol 1995:39:677-679.
18. Takenaka H, Zhang K, Diaz-Sanchez D, Tsien A, Saxon A: Enhanced human IgE results from exposure to the aromatic hydrocarbons in diesel exhaust: Direct effects on B cell IgE production, J Allergy Clin Immunol 1995;95:103-115.