Interleukin-18 enhances lipopolysaccharide-induced interferon-γ production in human whole blood cultures

Journal of Infectious Diseases

Volumn 178, Issue 6, 1998, Pages 1830-1834

  Puren, Adrian J ^a   Razeghi, Peter ^a   Fantuzzi, Giamila ^a   Dinarello, Charles A ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD CULTURE; CELL INTERACTION; CONCENTRATION (PARAMETERS); DISEASE ACTIVITY; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; PRIORITY JOURNAL;

ADULT; BLOOD CELLS; CELLS, CULTURED; DRUG SYNERGISM; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-18; INTERLEUKIN-6; INTERLEUKIN-8; KINETICS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; REFERENCE VALUES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031766791     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314481     Document Type: Article

References (13)

1. Billiau A. Interferon-γ: biology and role in pathogenesis. Adv Immunol 1996;62:61-130.
2. Nakamura K, Okamura H, Wada M, Nagata K, Tamura T. Endotoxin-induced serum factor that stimulates gamma interferon production. Infect Immun 1989;57:590-5.
3. Okamura H, Nagata K, Komatsu T, et al. A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock. Infect Immun 1995;63:3966-72.
4. Okamura H, Tsutsui H, Komatsu T, et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995;378:88-91.
5. Heremans H, van Damme J, Dillen C, Dikman R, Billiau A. Interferon-γ, a mediator of lethal lipopolysaccharide-induced Shwartzman-like shock in mice. J Exp Med 1990;171:1853-61.
6. Car BD, Eng VM, Schnyder B, et al. Interferon γ receptor deficient mice are resistant to endotoxic shock. J Exp Med 1994;179:1437-44.
7. + human blood mononuclear cells. J Clin Invest 1998;101:711-24.
8. Fuchs AC, Granowitz EV, Shapiro L, et al. Clinical, hematologic, and immunologic effects of interleukin-10 in humans. J Clin Immunol 1996;16:291-303.
9. Converse PJ, Jones SL, Asemborski J, Vlahov D, Graham NMH. Comparison of a tuberculin interferon-γ assay with the tuberculin skin test in high-risk adults: effect of human immunodeficiency virus infection. J Infect Dis 1997;176:144-50.
10. Nerad JL, Griffiths JK, van der Meer JWM, et al. Interleukin-1β (IL-1β), IL-1 receptor antagonist, and TNF-α production in whole blood. J Leukoc Biol 1992;52:687-92.
11. Petrovsky N, Harrison LC. HLA class II-associated polymorphism of interferon-γ production. Hum Immunol 1997;53:12-6.
12. Elsässer-Beile U, von Kleist S, Gallati H. Evaluation of a test system for measuring cytokine production in human whole blood cultures. J Immunol Methods 1991;139:191-5.
13. Dettke M, Scheidt P, Prange H, Kirchner H. Correlation between interferon production and clinical disease activity in patients with multiple sclerosis.