Cancer vaccine: Identification of human tumor antigens by serex

Cancer Journal

Volumn 6, Issue SUPPL. 3, 2000, Pages

  Chen, Yao Tseng ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR ANTIGEN;

ANTIGEN EXPRESSION; CANCER IMMUNOTHERAPY; CANCER SCREENING; CONFERENCE PAPER; DNA DETERMINATION; GENE LIBRARY; GENE OVEREXPRESSION; IMMUNOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; SEROLOGY;

ANTIGENS, NEOPLASM; CANCER VACCINES; HUMANS; MALE; NEOPLASMS; SEROLOGIC TESTS;

EID: 0033942936     PISSN: 15289117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (46)

1. Boon T, van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J Exp Med 1996;183:725-729.
2. Rosenberg SA. A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity 1999;10:281-287.
3. Sahin U, Türeci Ö, Schmitt H et al. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Natl Acad Sci USA 1995;92:11810-11813.
4. Türeci Ö, Schmitt H, Fadle N et al. Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. J Biol Chem 1997;272:6416-6422.
5. Güre AO, Türeci Ö, Sahin U et al. SSX, a multigene family with several members transcribed in normal testis and human cancer. Int J Cancer 1997;72:965-971.
6. Sahin U, Türeci O, Dahin U et al. Identification of a meiosis-specific protein as a new member of the class of cancer/testis antigens. Proc Natl Acad Sci USA 1998;95:5211-5216.
7. Chen YT, Güre AO, Tsang S et al. Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library. Proc Natl Acad Sci USA 1998;95:6919-6923.
8. Güre AO, Stockert E, Scanlan MJ et al. Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer. Proc Natl Acad Sci USA, in press.
9. O'Neill MJ, Sinclair AH. Isolation of rare transcripts by representational difference analysis. Nucleic Acids Res 1997;25:2681-2682.
10. Güre A, Stockert E, Arden KC et al. CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational difference analysis. Int J Cancer 2000;85:726-732.
11. Chen YT, Scanlan M, Sahin U et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Natl Acad Sci USA 1997;94:1914-1918.
12. Scanlan MJ, Chen YT, Williamson B et al. Characterization of human colon cancer antigens recognized by autologous antibodies. Int J Cancer 1998;76:652-658.
13. Brass N, Heckel D, Sahin U et al. Translation initiation factor eIF-4gamma is encoded by an amplified gene and induces an immune response in squamous cell lung carcinoma. Hum Mol Genet 1997;6:33-39.
14. Brass N, Racz A, Bauer C et al. Role of amplified genes in the production of autoantibodies. Blood 1999;93:2158-2166.
15. Güre AO, Altorki NK, Stockert E et al. Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21. Cancer Res 1998;58:1034-1041.
16. Scanlan MJ, Gordan JD, Williamson B et al. Antigens recognized by autologous antibody in patients with renal cell carcinoma. Int J Cancer, 1999;83:456-464.
17. Obata Y. SEREX analysis of gastric cancer antigens. In: Cancer Vaccine 1998. New York: Cancer Research Institute.
18. Jäger D, Stockert E, Scanlan MJ et al. Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue specific ING1 transcripts and a homolog gene. Cancer Res 1999;59:6197-6204.
19. Ling M, Wen YJ, Lim SH. Prevalence of antibodies against proteins derived from chronic myeloid leukemia. Blood 1998;92:4764-4770.
20. Van den Eynde BJ, van der Bruggen P. T cell defined tumor antigens. Curr Opin Immunol 1997;9:684-693.
21. Lucas S, De Smet C, Arden KC et al. Identification of a new MAGE gene with tumor-specific expression by representational difference analysis. Cancer Res 1998;58:743-752.
22. Lethé B, Lucas S, Michaux L et al. LAGE-1: a new gene with tumor specificity. Int J Cancer 1998;76:903-908.
23. Scanlan MJ, Altorki NK, Güre AO et al. Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene CT9. Cancer Lett, in press.
24. Zorn E, Hercend T. A MAGE-6-encoded peptide is recognized by expanded lymphocyte. 1999;29:602-607.
25. Crew AJ, Clark J, Fisher C et al. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. EMBO J 1994;14:2333-2340.
26. De Smet C, De Backer O, Faraoni I et al. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. Proc Natl Acad Sci USA 1996;93:7149-7153.
27. Meuwissen RJL, Meerts I, Hoovers JMN et al. Human synaptonemal protein 1 (SCP1): isolation and characterization of the cDNA and chromosomal localization of the gene. Genomics 1997;39:377-384.
28. Jones MH, Numata M, Shimane M. Identification and characterization of BRDT: a testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh. Genomics 1997;45:529-534.
29. Geiger B, Ayalon O. Cadherins. Annu Rev Cell Biol 1992;8:307-332.
30. Takeichi M. Cadherins in cancer: implications for invasion and metastasis. Curr Opin Cell Biol 1993;5:806-811.
31. Guilford P, Hopkins J, Harraway J et al. E-cadherin germline mutations in familial gastric cancer. Nature 1998;392:402-405.
32. Kok K, Naylor SL, Buys CH. Deletions of the short arm of chromosome 3 in solid tumors and the search for tumor suppressor genes. Adv Cancer Res 1997;71:27-92.
33. Van den Berg A, Hulsbeek MF, de Jong D et al. Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis. Genes Chromosomes Cancer 1996;15:64-72.
34. Schlichtholz B, Legros Y, Gillet D et al. The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot. Cancer Res 1992;52:6380-6384.
35. Türeci Ö, Sahin U, Vollmar E et al. Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers. Proc Natl Acad Sci USA 1998;95:7608-7613.
36. Zhang JY, Chan EKL, Peng XX et al. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med 1999;189:1101-1110.
37. Reich NC, Oren M, Levine AJ. Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol Cell Biol 1983;3:2143-2150.
38. Müller-Pillasch F, Lacher U, Wallrapp C et al. Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein. Oncogene 1997;14:2729-2733.
39. Scanlan, MJ, Williamson B, Jungbluth A et al. Isoforms of the human PDZ-73 protein exhibit differential tissue expression. Biochim Biophys Acta 1999;1445:39-52.
40. Herrmann M, Hagenhofer M, Kalden JR. Retrovirus and systemic lupus erythematosus. Immunol Rev 1996;152:145-156.
41. Walchner M, Leib-Mosch C, Messer G et al. Endogenous retroviral sequences in rhe pathogenesis of systemic autoimmune disease. Arch Dermatol 1997;133:767-771.
42. Herbst H, Sauter M, Mueller-Lantzsch N. Expression of human endogenous retrovirus K elements in germ cell and trophoblastic tumors. Am J Pathol 1996;149:1727-1735.
43. Boller K, Janssen O, Schuldes H et al. Characterization of the antibody response specific for the human endogenous retrovirus HTDV/HERV-K. J Virol 1997;71:4581-4588.
44. Jäger E, Chen YT, Drijfout JW et al. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of HLA-A2-binding peptide epitopes. J Exp Med 1998;187:265-270.
45. Jäger E, Jäger D, Karbach J et al. Identification of NY-ESO-1 epitopes presenred by HLA-DRB40101-0103 and recognized by CD4+ T lymphocytes of patients with NY-ESO-1 expressing melanomas. J Exp Med 2000;191:625-630.
46. Stockert E, Jäger E, Chen YT et al. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J Exp Med 1998;187:1349-1354.