메뉴 건너뛰기




Volumn 48, Issue 1, 2000, Pages 49-59

Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression

Author keywords

Cytochrome P450; Liver cholestasis; P glycoprotein; Taurochenodeoxycholic acid; Taurohyodeoxycholic acid

Indexed keywords

AMINOPYRINE N DEMETHYLASE; CYTOCHROME P450 3A; CYTOCHROME P450 REDUCTASE; GLYCOPROTEIN P; HYODEOXYCHOLIC ACID; LIVER PROTECTIVE AGENT; TAUROCHENODEOXYCHOLIC ACID; TESTOSTERONE; VINBLASTINE;

EID: 0033940813     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (58)
  • 2
    • 0342662084 scopus 로고
    • Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat
    • Kitani K, Ohta M, Kanai S. Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat. Am J Physiol 1985;248:G407-G417.
    • (1985) Am J Physiol , vol.248
    • Kitani, K.1    Ohta, M.2    Kanai, S.3
  • 3
    • 0009824490 scopus 로고
    • Tauro α-muricholate is as effective as Tauro β-muricholate and tauroursodeoxycholate in preventing the hepatocyte damage caused by continuous infusion of taurochenodeoxycholate in the rat
    • Kitani K, Kanai S, Sato Y, Ohta M. Tauro α-muricholate is as effective as Tauro β-muricholate and tauroursodeoxycholate in preventing the hepatocyte damage caused by continuous infusion of taurochenodeoxycholate in the rat. Hepatology 1994;19:1011-12.
    • (1994) Hepatology , vol.19 , pp. 1011-1012
    • Kitani, K.1    Kanai, S.2    Sato, Y.3    Ohta, M.4
  • 4
    • 0021054763 scopus 로고
    • Glycoursodeoxycholate is as effective as taurochenodeoxycholate in preventing the taurocholate-induced cholestasis in the rat
    • Kanai S, Kitani K. Glycoursodeoxycholate is as effective as taurochenodeoxycholate in preventing the taurocholate-induced cholestasis in the rat. Res Commun Chem Pathol Pharmacol 1983;42:423-30.
    • (1983) Res Commun Chem Pathol Pharmacol , vol.42 , pp. 423-430
    • Kanai, S.1    Kitani, K.2
  • 6
    • 0029894488 scopus 로고    scopus 로고
    • Synthesis and physicochemical, biological and pharmacological properties of new bile acids amidated with cyclic amino acids
    • Roda A, Cerré C, Manetta AC, Cainelli G, Umani-Ronchi A, Panunzio M. Synthesis and physicochemical, biological and pharmacological properties of new bile acids amidated with cyclic amino acids. J Med Chem 1996;39:2270-6.
    • (1996) J Med Chem , vol.39 , pp. 2270-2276
    • Roda, A.1    Cerré, C.2    Manetta, A.C.3    Cainelli, G.4    Umani-Ronchi, A.5    Panunzio, M.6
  • 7
    • 0020626591 scopus 로고
    • The influence of bile salt structure on self association in aqueous solutions
    • Roda A, Hofmann AF, Mysels KJ. The influence of bile salt structure on self association in aqueous solutions. J Biol Chem 1983; 258:6362-70.
    • (1983) J Biol Chem , vol.258 , pp. 6362-6370
    • Roda, A.1    Hofmann, A.F.2    Mysels, K.J.3
  • 8
    • 0025025867 scopus 로고
    • Bile acids structure-activity relationship: Evaluation of bile acid lipophilicity using 1-octanol/ water partition coefficient and reverse phase HPLC
    • Roda A, Minutello A, Angelotti MA, Fini A. Bile acids structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/ water partition coefficient and reverse phase HPLC. J Lipid Res 1990; 31:1433-43.
    • (1990) J Lipid Res , vol.31 , pp. 1433-1443
    • Roda, A.1    Minutello, A.2    Angelotti, Ma.3    Fini, A.4
  • 9
    • 0020031555 scopus 로고
    • Tauroursodeoxycholate prevents taurocholate-induced cholestasis in the rat
    • Kitani K, Kanai S, Ohhta M. Tauroursodeoxycholate prevents taurocholate-induced cholestasis in the rat. Life Sci 1982;30:515-23.
    • (1982) Life Sci , vol.30 , pp. 515-523
    • Kitani, K.1    Kanai, S.2    Ohhta, M.3
  • 12
    • 0025247125 scopus 로고
    • Hepatic injury induced by bile salts: Correlation between biochemical and morphological events
    • Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K. Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology 1990;12:1216-21.
    • (1990) Hepatology , vol.12 , pp. 1216-1221
    • Schmucker, D.L.1    Ohta, M.2    Kanai, S.3    Sato, Y.4    Kitani, K.5
  • 13
    • 0021335877 scopus 로고
    • Ursodeoxycholic acid: A review of its pharmacological properties and therapeutic efficacy
    • Ward A, Brogden AN, Heel RC, Speight TM, Avery GS. Ursodeoxycholic acid: a review of its pharmacological properties and therapeutic efficacy. Drugs 1984;27:95-131.
    • (1984) Drugs , vol.27 , pp. 95-131
    • Ward, A.1    Brogden, A.N.2    Heel, R.C.3    Speight, T.M.4    Avery, G.S.5
  • 14
    • 0014752462 scopus 로고
    • Induction of rat liver alkaline phosphatase: The mechanism of the serum elevation in bile duct obstruction
    • Kaplan MM, Righetti A. Induction of rat liver alkaline phosphatase: the mechanism of the serum elevation in bile duct obstruction. J Clin Invest 1970;49:508-16.
    • (1970) J Clin Invest , vol.49 , pp. 508-516
    • Kaplan, M.M.1    Righetti, A.2
  • 15
    • 0020581616 scopus 로고
    • Increased synthesis of rat liver alkaline phosphatase by bile duct ligation
    • Kaplan MM, Onkubo A, Quaroni EG, Sze-Tu D. Increased synthesis of rat liver alkaline phosphatase by bile duct ligation. Hepatology 1983;3:433-9.
    • (1983) Hepatology , vol.3 , pp. 433-439
    • Kaplan, M.M.1    Onkubo, A.2    Quaroni, E.G.3    Sze-Tu, D.4
  • 16
    • 0025732697 scopus 로고
    • Hypercholeresis induced by unconjugated bile acids infusion correlates with recovery in bile of unconjugated bile acids
    • Gurantz D, Schteingart CD, Hagey LR, Steinbach JH, Grotmol T, Hofmann AF. Hypercholeresis induced by unconjugated bile acids infusion correlates with recovery in bile of unconjugated bile acids. Hepatology 1991;13:340-50.
    • (1991) Hepatology , vol.13 , pp. 340-350
    • Gurantz, D.1    Schteingart, C.D.2    Hagey, L.R.3    Steinbach, J.H.4    Grotmol, T.5    Hofmann, A.F.6
  • 17
    • 0032519643 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression by cytochrome P450 inducers in male and female rat livers
    • Salphati L, Bernet LZ. Modulation of P-glycoprotein expression by cytochrome P450 inducers in male and female rat livers. Biochemical Pharmacol 1998;55:387-95.
    • (1998) Biochemical Pharmacol , vol.55 , pp. 387-395
    • Salphati, L.1    Bernet, L.Z.2
  • 18
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistence mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistence mediated by the multidrug transporter. Annu Rev Biochem 1993;62: 385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 19
    • 0027345632 scopus 로고
    • Function and regulation of the human multidrug transporter
    • Chin KV, Pastan I, Gottesman MM. Function and regulation of the human multidrug transporter. Adv Cancer Res 1993;60:157-80.
    • (1993) Adv Cancer Res , vol.60 , pp. 157-180
    • Chin, K.V.1    Pastan, I.2    Gottesman, M.M.3
  • 20
    • 0028958628 scopus 로고
    • The biology of the P-glycoproteins
    • Leveille WC, Arias IM. The biology of the P-glycoproteins. J Membr Biol 1995;143:89-102.
    • (1995) J Membr Biol , vol.143 , pp. 89-102
    • Leveille, W.C.1    Arias, I.M.2
  • 22
  • 23
    • 0027714411 scopus 로고
    • Pharmacologic circumvention of multidrug resistance
    • Ford JM, Hait WN. Pharmacologic circumvention of multidrug resistance. Cytotechnology 1993;12:171-212.
    • (1993) Cytotechnology , vol.12 , pp. 171-212
    • Ford, J.M.1    Hait, W.N.2
  • 24
    • 0025253133 scopus 로고
    • Two members of the mouse mdr gene family confer multidrug resistence with overlapping but distinct drug specificities
    • Devault A, Gros P. Two members of the mouse mdr gene family confer multidrug resistence with overlapping but distinct drug specificities. Mol Cell Biol 1990;19:1652-63.
    • (1990) Mol Cell Biol , vol.19 , pp. 1652-1663
    • Devault, A.1    Gros, P.2
  • 26
    • 0030248322 scopus 로고    scopus 로고
    • Modulation of hepatic content and biliary excretion of P-glycoprotein in hepatocellular and obstructive cholestasis in rat
    • Accatino L, Pizarro M, Solis N, Koenig CS, Vollrath V, Chianale J. Modulation of hepatic content and biliary excretion of P-glycoprotein in hepatocellular and obstructive cholestasis in rat. J Hepatol 1996;25: 349-61.
    • (1996) J Hepatol , vol.25 , pp. 349-361
    • Accatino, L.1    Pizarro, M.2    Solis, N.3    Koenig, C.S.4    Vollrath, V.5    Chianale, J.6
  • 27
    • 0031965344 scopus 로고    scopus 로고
    • Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level
    • Smit WJ, Duin E, Steen H, Oosting R, Roggeveld J, Meijer DKF. Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level. Br J Pharm 1998;123:361-70.
    • (1998) Br J Pharm , vol.123 , pp. 361-370
    • Smit, W.J.1    Duin, E.2    Steen, H.3    Oosting, R.4    Roggeveld, J.5    Meijer, D.K.F.6
  • 29
    • 0025964121 scopus 로고
    • Expression and inducibility of drug-metabolising enzymes in novel murine liver epithelial cell lines and their ability to activate procarcinogens
    • . Paolini M, Barone M, Corsi C, Paganin C, Revoltella RP. Expression and inducibility of drug-metabolising enzymes in novel murine liver epithelial cell lines and their ability to activate procarcinogens. Cancer Res 1991;51:301-9.
    • (1991) Cancer Res , vol.51 , pp. 301-309
    • Paolini, M.1    Barone, M.2    Corsi, C.3    Paganin, C.4    Revoltella, R.P.5
  • 31
    • 77049138167 scopus 로고
    • Colorimetric estimation of formaldehyde by means of hantzsch reaction
    • Nash T. Colorimetric estimation of formaldehyde by means of Hantzsch reaction. Biochem J 1953;55:416-21.
    • (1953) Biochem J , vol.55 , pp. 416-421
    • Nash, T.1
  • 32
    • 0028897079 scopus 로고
    • Induction of CYP 2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers
    • Paolini M, Mesirca R, Pozzetti L, Sapone A, Cantelli-Forti G. Induction of CYP 2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers. Chem Biol Interact 1995;95:127-39.
    • (1995) Chem Biol Interact , vol.95 , pp. 127-139
    • Paolini, M.1    Mesirca, R.2    Pozzetti, L.3    Sapone, A.4    Cantelli-Forti, G.5
  • 33
    • 0024625072 scopus 로고
    • Genetically engineered V79 chinese hamster cell. Expression of purified cytochrome P4502b1 monooxygenase activity
    • Platt J, Molitor E, Doehmer I, Dogra S, Oesch F. Genetically engineered V79 Chinese hamster cell. Expression of purified cytochrome P4502B1 monooxygenase activity. Biochem Toxicol 1989;4:1-5.
    • (1989) Biochem Toxicol , vol.4 , pp. 1-5
    • Platt, J.1    Molitor, E.2    Doehmer, I.3    Dogra, S.4    Oesch, F.5
  • 34
    • 0021350036 scopus 로고
    • Assay of hepatic microsomal testosterone hydroxylases by high-performance liquid chromatography
    • Van der Hoeven TH. Assay of hepatic microsomal testosterone hydroxylases by high-performance liquid chromatography. Anal Biochem 1984;138:57-65.
    • (1984) Anal Biochem , vol.138 , pp. 57-65
    • Van Der Hoeven, T.H.1
  • 35
    • 0030772781 scopus 로고    scopus 로고
    • Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo
    • Paolini M, Pozzetti L, Sapone A, Biagi GL, Cantelli-Forti G. Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo. Br J Pharmacol 1997:;22:344-50.
    • (1997) Br J Pharmacol , vol.22 , pp. 344-350
    • Paolini, M.1    Pozzetti, L.2    Sapone, A.3    Biagi, G.L.4    Cantelli-Forti, G.5
  • 36
    • 0031587925 scopus 로고    scopus 로고
    • Oxidation of caffeine to theobromine and theophillyne is catalyzed primarily by flavin-containing monooxygenase in liver microsomes
    • Chung WA, Cha YN. Oxidation of caffeine to theobromine and theophillyne is catalyzed primarily by flavin-containing monooxygenase in liver microsomes. Biochem Biophys Res Comm 1997;235:685-8.
    • (1997) Biochem Biophys Res Comm , vol.235 , pp. 685-688
    • Chung, W.A.1    Cha, Y.N.2
  • 40
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 41
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Stachelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sei USA 1979;76:4350-4.
    • (1979) Proc Natl Acad Sei USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Stachelin, T.2    Gordon, J.3
  • 42
    • 0024532060 scopus 로고
    • Redox cycling of resorufin catalyzed by rat liver microsomal NADPH-cytochrome P450 reductase
    • Dutton DR, Reed GA, Parkinson A. Redox cycling of resorufin catalyzed by rat liver microsomal NADPH-cytochrome P450 reductase. Arch Biochem Biophys 1989;268:605-16.
    • (1989) Arch Biochem Biophys , vol.268 , pp. 605-616
    • Dutton, D.R.1    Reed, G.A.2    Parkinson, A.3
  • 43
    • 0016712763 scopus 로고
    • Quantitative determination of serum bile acids using a purified 3α dehydrogenase
    • Fausa O. Quantitative determination of serum bile acids using a purified 3α dehydrogenase. Scand J Gastroenterol 1975;10:747-51.
    • (1975) Scand J Gastroenterol , vol.10 , pp. 747-751
    • Fausa, O.1
  • 46
    • 0023238801 scopus 로고
    • High pressure liquid chromatographic analysis of conjugated bile acids in human bile: Simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids
    • Rossi SS, Converse JL, Hofmann AF. High pressure liquid chromatographic analysis of conjugated bile acids in human bile: simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids. J Lipid Res 1987;28:589-95.
    • (1987) J Lipid Res , vol.28 , pp. 589-595
    • Rossi, S.S.1    Converse, J.L.2    Hofmann, A.F.3
  • 47
    • 0028933740 scopus 로고
    • High-performance liquid chromatographic-electrospray mass spectrometric analysis of bile acids in biological fluids
    • Roda A, Gioacchini AM, Cerré C, Baraldini M. High-performance liquid chromatographic-electrospray mass spectrometric analysis of bile acids in biological fluids. J Chromatogr 1995;665: 281-94.
    • (1995) J Chromatogr , vol.665 , pp. 281-294
    • Roda, A.1    Gioacchini, A.M.2    Cerré, C.3    Baraldini, M.4
  • 49
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazake H, Mimura M, Inui Y, Guengerich FP. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994;270:414-23.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazake, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 50
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochromes P450 in the intestinal mucosa of rats and man
    • Watkins PB, Wrighton SA, Schuetz FG, Molowa DT, Guzelian PS. Identification of glucocorticoid-inducible cytochromes P450 in the intestinal mucosa of rats and man. J Clin Invest 1987;80: 1029-36.
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, F.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 53
    • 0025823086 scopus 로고
    • Lime course of mdr gene amplification during in vivo selection for dexorubicin-resistence and during reversed in murine leukemia L1210
    • Volm M, Mattern J, Pmmerenke EW. Lime course of mdr gene amplification during in vivo selection for dexorubicin-resistence and during reversed in murine leukemia L1210. Anticancer Res 1991;11: 579-85.
    • (1991) Anticancer Res , vol.11 , pp. 579-585
    • Volm, M.1    Mattern, J.2    Pmmerenke, E.W.3
  • 54
    • 0029115331 scopus 로고
    • Characterisation of taurochenodeoxycholic acid 6 alpha-hydroxylase from pig liver microsomes
    • Araya Z, Hellman U, Hansson R. Characterisation of taurochenodeoxycholic acid 6 alpha-hydroxylase from pig liver microsomes. Eur J Biochem 1995;231:855-61.
    • (1995) Eur J Biochem , vol.231 , pp. 855-861
    • Araya, Z.1    Hellman, U.2    Hansson, R.3
  • 55
    • 0028235746 scopus 로고
    • Bile acid inhibition of P-glycoprotein mediated transport in multidrug resistant cells and rat liver canalicular membrane vesicles
    • Mazzanti R, Fantappié O, Kamimoto Y, Gatmaitan Z, Gentilini P, Arias IM. Bile acid inhibition of P-glycoprotein mediated transport in multidrug resistant cells and rat liver canalicular membrane vesicles. Hepatology 1993;20:170-6.
    • (1993) Hepatology , vol.20 , pp. 170-176
    • Mazzanti, R.1    Fantappié, O.2    Kamimoto, Y.3    Gatmaitan, Z.4    Gentilini, P.5    Arias, I.M.6
  • 56
    • 0024371025 scopus 로고
    • The function of Gp170, the multidrug resistence gene product, in rat liver canalicular membrane vesicles
    • Kamimoto Y, Gatmaitan Z, Hsu J, Arias IM. The function of GP170, the multidrug resistence gene product, in rat liver canalicular membrane vesicles. J Biol Chem 1989;264:11693-8.
    • (1989) J Biol Chem , vol.264 , pp. 11693-11698
    • Kamimoto, Y.1    Gatmaitan, Z.2    Hsu, J.3    Arias, I.M.4
  • 57
    • 0029944613 scopus 로고    scopus 로고
    • Do intracellular organelles have any role in transport of bile acids by hepatocytes?
    • Erlinger S. Do intracellular organelles have any role in transport of bile acids by hepatocytes? J Hepatol 1996;24(suppl):88-93.
    • (1996) J Hepatol , vol.24 , Issue.SUPPL. , pp. 88-93
    • Erlinger, S.1
  • 58
    • 0029839564 scopus 로고    scopus 로고
    • Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: Relevance to drug metabolism in experimental cholestasis
    • Chen J, Farrell GC. Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis. J Gastoenterol Hepatology 1996;11:870-7.
    • (1996) J Gastoenterol Hepatology , vol.11 , pp. 870-877
    • Chen, J.1    Farrell, G.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.