Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level

British Journal of Pharmacology

Volumn 123, Issue 3, 1998, Pages 361-370

  Smit, Johan W ^a,b   Duin, Erik ^a   Steen, Herman ^a   Oosting, Roelof ^a   Roggeveld, Jan ^a   Meijer, Dirk K F ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Cationic drugs; Drug interaction; Hepatobiliary transport; Lipophilicity; P glycoprotein

Indexed keywords

AMMONIUM DERIVATIVE; ANTHRACYCLINE ANTIBIOTIC AGENT; DOXORUBICIN; GLYCOPROTEIN P; NEUROMUSCULAR BLOCKING AGENT; PROCAINAMIDE ETHOBROMIDE; QUINIDINE; QUININE; ROCURONIUM; TRIBUTYLMETHYLAMMONIUM; VERAPAMIL; VINBLASTINE; VINCRISTINE SULFATE;

ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; DRUG EXCRETION; ISOLATED LIVER; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANDROSTANOLS; ANIMALS; BILIARY TRACT; DOXORUBICIN; LIVER; MALE; P-GLYCOPROTEIN; PROTEIN BINDING; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR;

EID: 0031965344     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701606     Document Type: Article

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