Endoscopic treatment of acute esophageal variceal bleeding

Drugs of Today

Volumn 36, Issue 6, 2000, Pages 339-353

  Kovacs, Thomas O ^a   Jensen, Dennis M ^a  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYANOACRYLATE; MORRHUATE SODIUM; OCTREOTIDE; POLIDOCANOL; POLYMER; PROPRANOLOL; SCLEROSING AGENT; SOMATOSTATIN; TETRADECYL SULFATE SODIUM; VASODILATOR AGENT; VASOPRESSIN;

CLINICAL TRIAL; COST BENEFIT ANALYSIS; DIGESTIVE SYSTEM HEMORRHAGE; ENDOSCOPIC SCLEROTHERAPY; ENDOSCOPIC SURGERY; ENDOSCOPIC THERAPY; ESOPHAGUS PERFORATION; ESOPHAGUS STRICTURE; ESOPHAGUS ULCER; ESOPHAGUS VARICES BLEEDING; HEMOSTASIS; HUMAN; REVIEW; SHUNTING; VEIN LIGATION;

EID: 0033936356     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2000.36.6.584256     Document Type: Review

References (87)

1. Kovacs, T.O.G., Jensen, D.M. Endoscopic control of gastroduodenal hemorrhage. Ann Rev Med 1987, 38: 267-77.
2. Kovacs, T.O.G., Jensen, D.M. Therapeutic endoscopy in upper gastrointestinal bleeding. In: Gastrointestinal Emergencies, 2nd Ed. Taylor, M.B., Gollan, J.L., Steer, M.L., Wolfe, M.M. (Eds.). Williams & Wilkins: Philadelphia 1997, 181-98.
3. Garceau, A.J., Chalmers, T.C. The natural history of cirrhosis: I. Survival with esophageal varices. The Boston Inter-Hospital Liver Group. N Engl J Med 1963, 268: 469-73.
4. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study. The North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices.. N Engl J Med 1988, 319: 983-9.
5. Graham, D.Y., Smith, J.L. The course of patients after variceal hemorrhage. Gastroenterology 1981, 80: 800-9.
6. Liebler, J.M., Benner, K., Putnam, T., Vollmer, W. M. Respiratory complications in critically ill medical patients with acute upper gastrointestinal bleeding. Crit Care Med 1991, 19: 1152-7.
7. Sutton, R. Upper gastrointestinal bleeding in patients with esophageal varices. What is the most common source? Am J Med 1987, 83: 273-5.
8. Tabibian, N., Graham, D.Y. Source of upper gastrointestinal bleeding in patients with esophageal varices seen at endoscopy. J Clin Gastroenterol 1987, 9: 279-82.
9. Buset, M., Des Marez, B., Baize, M., Bourgeois, N., Cremer, M. Bleeding esophagogastric varices: An endoscopic study. Am J Gastroenterol 1987, 82: 241-4.
10. Jutabha, R., Jensen, D.M., Kovacs, T.O.G. et al. Prospective study of the causes and outcomes of severe UGI hemorrhage in cirrhotics. Gastrointest Endosc 1999, 49: Abst 167.
11. Cales, P., Zabotto, B., Meskens, C. et al. Gastroesophageal endoscopic features in cirrhosis: Observer variability, interassociations, and relationships to hepatic dysfunction. Gastroenterology 1990, 98: 156-62.
12. Lebrec, D., DeFleury, P., Rueff, B., Nahum, H., Benhamou, J.P. Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis. Gastroenterology 1980, 79: 1139.
13. D'Amico, G., Pagliaro, L., Bosch, J. The treatment of portal hypertension: A meta-analytic review. Hepatology 1995, 22: 332-54.
14. Burroughs, A.K., Hamilton, G., Phillips, A., Mezzanotte, G., McIntyre, N., Hobbs, K.E. A comparison of sclerotherapy with staple transection of the esophagus for emergency control of bleeding from esophageal varices. N Engl J Med 1989, 321: 857-62.
15. Hartigan, P.M., Gebhard, R.L., Gregory, P.B. Sclerotherapy for actively bleeding esophageal varices in male patients with cirrhosis. Veterans Affairs Cooperative Variceal Sclerotherapy Group. Gastroinest Endosc 1997, 46: 1-7.
16. Terblanche, J., Burroughs, A.K., Hobbs, K. Controversies in the management of bleeding esophageal varices (1). N Engl J Med 1989, 320: 1393-8.
17. Terblanche, J., Burroughs, A.K., Hobbs, K. Controversies in the management of bleeding esophageal varices (2). N Engl J Med 1989, 320: 1469-75.
18. Planas, R., Quer, J.C., Boix, J. et al. A prospective randomized trial comparing somatostatin and sclerotherapy in the treatment of acute variceal bleeding. Hepatology 1994, 20: 370-5.
19. Shields, R., Jenkins, S.A., Baxter, J.N. et al. A prospective randomized controlled trial comparing the efficacy of somatostatin with injection sclerotherapy in the control of bleeding esophageal varices. J Hepatol 1992, 15: 128-37.
20. Sung, J.J.Y., Chung, S.C.S., Lai, C.W. et al. Octreotide infusion or emergency sclerotherapy for variceal hemorrhage. Lancet 1993, 342: 637-41.
21. Barsoum, M.S., Bolous, F.I., El-Rooby, A.A., Rizk-Allah, M.A., Ibrahim, A.S. Tamponade and injection sclerotherapy in the management of bleeding esophageal varices. Br J Surg 1982, 69: 76-8.
22. Burroughs, A.K., McCormick, P.A., Siringo, S. et al. Prospective randomized trial of long term sclerotherapy for variceal rebleeding using the same protocol to treat rebleeding in all patients: Final report. Hepatology 1989, 10: Abst 579.
23. Sclerotherapy after first variceal hemorrhage in cirrhosis: A randomized multicenter trial. The Copenhagen Esophageal Varices Sclerotherapy Project. N Engl J Med 1984, 311: 1594-600.
24. Sclerotherapy for male alcoholics with cirrhosis who have bled from esophageal varices: Results of a randomized multicenter clinical trial. The Veterans Affairs Cooperative Variceal Sclerotherapy Group. Hepatology 1994, 20: 618-25.
25. Korula, J., Balart, L.A., Radvan, G. et al. A prospective randomized controlled trial of chronic esophageal variceal sclerotherapy. Hepatology 1985, 5: 584-9.
26. Soderlund, C., Ihre, T. Endoscopic sclerotherapy versus conservative management of bleeding esophageal varices: A 5 year prospective controlled trial of emergency and long term treatment. Acta Chir Scand 1985, 151: 449-56.
27. Terblanche, J., Bornman, P.C., Kahn, D. et al. Failure of repeated injection sclerotherapy to improve long-term survival after esophageal variceal bleeding: A five year prospective controlled clinical trial. Lancet 1983, 2: 1328-32.
28. Westaby, D., MacDougall, B.R., Williams, R. Improved survival following injection sclerotherapy for esophageal varices: Final analysis of a controlled trial. Hepatology 1985, 5: 827-30.
29. Rossi, V., Cales, P., Pascal, B. et al. Prevention of recurrent variceal bleeding in alcoholic cirrhotic patients: Prospective controlled trial of propranolol and sclerotherapy. J Hepatol 1991, 12: 283-9.
30. Dasarathy, S., Divinedi, M., Bharagava, D.K., Sundaram, K.R., Ramachandran, K. A prospective randomized trial comparing repeated endoscopic sclerotherapy and propranolol in decompensated (Child's B and C) cirrhosis patients. Hepatology 1992, 16: 89-94.
31. Teres, J., Bosch, J., Bordas, J.M. et al. Propranolol versus sclerotherapy in preventing variceal rebleeding: A randomized controlled trial. Gastroenterology 1993, 105: 1508-14.
32. Dollet, J.M., Champigneulle, B., Patgris, A., Bigard, M.A., Gaucher, P. Endoscopic sclerotherapy versus propranolol after hemorrhage caused by rupture of esophageal varices in patients with cirrhosis: Results of a 4-year randomized study. Gastroenterol Clin Biol 1988, 12: 234-9.
33. Westaby, D., Poison, R.J., Gimson, A.E., Hayes, P.C., Hayllar, K., Williams R. A controlled trial of oral propranolol compared with injection sclerotherapy for long term management of variceal bleeding. Hepatology 1990, 11: 353-9.
34. Fleig, W.E., Stange, E.F., Hunecke, R. et al. Prevention of recurrent bleeding in cirrhosis with recent variceal hemorrhage. Prospective, randomized comparison of propranolol and sclerotherapy. Hepatology 1987, 7: 355-61.
35. Alexandrino, P.T., Alves, M.M., Correia, J.P. Propranolol or endoscopic sclerotherapy in the prevention of recurrence of variceal bleeding: A prospective randomized controlled trial. J Hepatol 1988, 7: 175-85.
36. Lundell, L., Leth, R., Lind, T., Lonroth, H., Sjovall, M., Olbe, L. Evaluation of propranolol for prevention of recurrent bleeding from esophageal varices between sclerotherapy sessions. Acta Chir Scand 1990, 156: 711-5.
37. Vickers, C., Rhodes, J., Chesner, I. et al. Prevention of rebleeding from esophageal varices: Two year follow-up of a prospective controlled trial of propranolol in addition to sclerotherapy. J Hepatol 1994, 21: 81-7.
38. Acharya, S.K., Dasarathry, S., Saksena, S., Pande, J. N. A prospective randomized study to evaluate propranolol in patients undergoing long-term endoscopic sclerotherapy. J Hepatol 1993, 19: 291-300.
39. O'Connor, K.W., Lehman, G., Yune, H. et al. Comparison of three nonsurgical treatments for bleeding esophageal varices. Gastroenterology 1989, 96: 899-906.
40. Vinel, J.P., Lamouliatte, H., Cales, P. et al. Propranolol reduces the rebleeding rate during endoscopic sclerotherapy before variceal obliteration. Gastroenterology 1992, 102: 1760-3.
41. Avgerinos, A., Rekoumis, G., Klonis, C. et al. Propranolol in the prevention of recurrent upper gastrointestinal bleeding in patients with cirrhosis undergoing endoscopic sclerotherapy: A randomized controlled trial. J Hepatol 1993, 19: 301-11.
42. Westaby, D., Melia, W., Hegarty, J., Gimson, A.E., Stellon, A.J., Wiliams, R. Use of propranolol to reduce the rebleeding rate during injection sclerotherapy prior to variceal obliteration. Hepatology 1986, 6: 673-5.
43. Ink, O., Martin, T., Poynard, T. et al. Does elective sclerotherapy improve the efficacy of long-term propranolol for prevention of recurrent bleeding in patients with severe cirrhosis? A prospective multicenter randomized trial. Hepatology 1992, 16: 912-9.
44. Rikkers, L.F., Jin, G. Surgical management of acute variceal hemorrhage. World J Surg 1994, 18: 193-9.
45. Spina, G.P., Santambrogio, R., Opocher, E. et al. Distal splenorenal shunt versus endoscopic sclerotherapy in the prevention of variceal rebleeding: First stage of a randomized controlled trial. Ann Surg 1990, 211: 178-86.
46. Cello, J.P., Grendell, J.H., Crass, R.A. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and variceal hemorrhage. N Engl J Med 1984, 311: 1589-94.
47. Cello, J.P., Grendell, J.H., Crass, R.A. et al. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and acute variceal hemorrhage. Long term follow-up. N Engl J Med 1987, 316: 11-5.
48. Fass, R., Landau, O., Kovacs, T.O., Ippoliti, A. Esophageal motility abnormalities in cirrhotic patients before and after endoscopic variceal treatment. Am J Gastroenterol 1997, 92: 941-6.
49. Sauerbruch, T., Schepke, M. Sclerotherapy is out - nearly. Endoscopy 1997, 29: 281-2.
50. Soehendra, N., Binmoeller, K.F. Is sclerotherapy out? Endoscopy 1997, 29: 283-4.
51. Stiegmann, G.V., Goff, J.S., Michaletz-Onody, P.A. et al. Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices. N Engl J Med 1992, 326: 1527-32.
52. Gimson, A.E., Ramage, J.K., Panos, M.Z. et al. Randomized trial of variceal banding ligation versus injection sclerotherapy for bleeding esophageal varices. Lancet 1993, 342: 391-4.
53. Laine, L., El-Newihi, H.M., Migikovsky, B., Sloane, R., Garcia, F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Ann Intern Med 1993, 119: 1-7.
54. Lo, G.H., Lai, K.H., Cheng, J.S. et al. A prospective randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices. Hepatology 1995, 22: 466-71.
55. Hou, M.C., Liu, H.C., Kuo, B.I.T. et al. Comparison of endoscopic variceal injection sclerotherapy and ligation for the treatment of esophageal variceal hemorrhage: A prospective randomized trial. Hepatology 1995, 21: 1517-22.
56. Jensen, D.M., Kovacs, T.O., Randall, G.M. et al. Emergency sclerotherapy versus rubber band ligation for actively bleeding esophagogastric varices in a randomized, prospective study. Gastrointest Endosc 1994, 40: Abst 77.
57. Laine, L., Cook, D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding: A meta-analysis. Ann Intern Med 1995, 123: 280-7.
58. Baroncini, D., Milandri, G., Borioni, D. et al. A prospective randomized trial of sclerotherapy versus ligation in the elective treatment of bleeding esophageal varices. Endoscopy 1997, 29: 235-40.
59. Jensen, D.M., Kovacs, T.O., Randall, G.M. et al. A randomized prospective study of emergency sclerotherapy versus banding for bleeding gastric varices: Initial results. Am J Gastroenterol 1993, 88: Abst 150.
60. Jensen, D.M., Kovacs, T.O., Jutabha, R. Final results of a randomized prospective trial of combination rubber band ligation and sclerotherapy versus sclerotherapy alone for hemostasis of bleeding esophageal varices. Gastroenterology 1996, 110: A1222.
61. Koutsomanis, D. Endoscopic variceal ligation combined with low-volume sclerotherapy. Gastroenterology 1992, 102: A835.
62. Laine, L., Stein, C., Sharma, V. Randomized comparison of ligation versus ligation plus sclerotherapy in patients with bleeding esophageal varices. Gastroenterology 1996, 110: 529-33.
63. Saeed, Z.A., Stiegmann, G.V., Ramirez, R.C. et al. Endoscopic variceal ligation is superior to combined ligation and sclerotherapy: A multicenter prospective randomized trial. Hepatology 1997, 25: 71-4.
64. Al Traif, I., Fachartz, F.S., Al Jumah, A. et al. Randomized trial of ligation versus combined ligation and sclerotherapy for bleeding esophageal varices. Gastrointest Endosc 1999, 56: 1-6.
65. Argonz, J., Kravetz, D., Suarez, A. et al. Variceal band ligation and variceal band ligation plus sclerotherapy in the prevention of recurrent variceal bleeding in cirrhotic patients: A randomized, prospective and controlled trial. Gastrointest Endosc 2000, 51: 157-63.
66. Umehara, M., Onda, M., Tajiri, T., Toba, M., Yoshida, H., Yamashita, K. Sclerotherapy plus ligation versus ligation for the treatment of esophageal varices: A prospective randomized trial. Gastrointest Endosc 1999, 50: 7-12.
67. Gralnek, I.M., Jensen, D.M. Cost assessment in the management of variceal bleeding. Clin Liver Dis 1997, 1:45-58.
68. Gralnek, I.M., Jensen, D.M., Kovacs, T.O. et al. The economic impact of esophageal variceal hemorrhage: Cost-effectiveness implications of endoscopic therapy. Hepatology 1999, 29: 44-50.
69. Gotlib, J.P. Endoscopic obturation of esophageal and gastric varices with a cyanoacrylic tissue adhesive. Can J Gastroenterol 1990, 4: 637-8.
70. Lux, G., Retterspitz, M., Stabenow-Lahbauer, U., Langer, M., Altendorf-Hofmann, A., Bozkurt, T. Treatment of bleeding esophageal varices with cyanoacrylate and polidocanol, or polidocanol alone: Results of a prospective study of an unselected group of patients with cirrhosis of the liver. Endoscopy 1997, 29: 241-6.
71. Chan, L.Y., Sung, J.J.Y. Review article: The role of pharmaco-therapy for acute variceal hemorrhage in the era of endoscopic hemostasis. Aliment Pharmacol Ther 1997, 11: 45-50.
72. Bosch, J. Medical treatment of portal hypertension. Digestion 1998, 59: 547-55.
73. Kravetz, D., Bosch, J., Teres, J., Bruix, J., Rimola, A., Rodes, J. Comparison of intravenous somatostatin and vasopressin infusions in treatment of acute variceal hemorrhage. Hepatology 1984, 4: 442-6.
74. Jenkins, S.A., Baxter, J.N., Corbett, W., Devitt, P., Ware, J., Shields, R. A prospective randomized controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal hemorrhage. Br Med J 1985, 290: 275-8.
75. Walker, S., Kreichgauer, H.P., Bode, J.C. Terlipressin versus somatostatin in bleeding esophageal varices: A controlled, double blind study. Hepatology 1992, 15: 1023-30.
76. Jaramillo, J.L., de la Mata, M., Mino, G., Costan, G., Gomez-Camacho, F. Somatostatin versus Sengstaken balloon tamponade for primary hemostasis of bleeding esophageal varices: A randomized pilot study. J Hepatol 1991, 12: 100-5.
77. Avgerinos, A., Klonis, C., Rekoumis, G., Gouma, P., Papadimitriou, N., Raptis, S. A prospective randomized trial comparing somatostatin, balloon tamponade and the combination of both methods in the management of acute variceal hemorrhage. J Hepatol 1991, 13: 78-83.
78. Junquera, F., Lopez-Talavera, J.C., Mearin, F. et al. Somatostatin plus isosorbide-5-mononitrate versus somatostatin in the control of acute gastroesophageal variceal bleeding: A double blind, randomized, placebo-controlled clinical trial. Gut 2000, 46: 127-32.
79. Tarnasky, P.R., Kovacs, T.O., Leung, F.W., Hirabayashi, K., Jensen, D.M. Octreotide decreases gastric mucosal blood flow: A controlled assessment by endoscopic reflectance spectrophotometry. Gastrointest Endosc 1994, 40: 56-61.
80. Hwang, S.J., Lin, H.C., Chang, C.F. et al. A randomized controlled trial comparing octreotide and vasopressin in the control of acute esophageal variceal bleeding. J Hepatol 1992, 16: 320-5.
81. McKee, R. A study of octreotide in esophageal varices. Digestion 1990, 45: 60-5.
82. Prirnignani, M., Andreoni, B., Carpinelli, L. et al. Sclerotherapy plus octreotide versus sclerotherapy alone in the prevention of early rebleeding from esophageal varices: A randomized double-blind placebo-controlled multicenter trial. New Italian Endoscopic Club. Hepatology 1995, 21: 1322-7.
83. Jenkins, S.A., Shields, R., Davies, M. et al. A multicentre randomised trial comparing octreotide and injection sclerotherapy in the management and outcome of acute variceal haemorrhage. Gut 1997, 41: 526-33.
84. Besson, I., Ingrand, P., Person, B. et al. Sclerotherapy with or without octreotide for acute variceal bleeding. N Engl J Med 1995, 333: 555-60.
85. Sung, J.J., Chung, S.C., Yung, M.Y. Prospective randomized study of effects of octreotide on rebleeding from esophageal varices after endoscopic ligation. Lancet 1995, 346: 1666-9.
86. Bernard, B., Lebrec, D., Mathurin, P., Opolon, P., Poynard, T. β-Adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis: A meta-analysis. Hepatology 1997, 25: 63-70.
87. Grace, N.D. Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension. Am J Gastroenterol 1997, 92: 1081-91.