Recombinant pI(Cln) forms highly cation-selective channels when reconstituted into artificial and biological membranes

Journal of General Physiology

Volumn 112, Issue 6, 1998, Pages 727-736

  Canhui, L I ^a   Breton, Sylvie ^b   Morrison, Rebecca ^c   Cannon, Carolyn L ^d   Emma, Francesco ^d   Sanchez Olea, Roberto ^d   Bear, Christine ^a   Strange, Kevin ^c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Cell volume; Liposomes; Planar lipid bilayer; Recombinant protein; Swelling activated anion channels

Indexed keywords

CASEIN KINASE II; CATION CHANNEL; CHLORIDE ION; CHLORINE 36; GLUTAMIC ACID; LIPOSOME; MEGLUMINE; MEMBRANE PROTEIN; POTASSIUM CHLORIDE; POTASSIUM ION; RECOMBINANT PROTEIN; RUBIDIUM 86; CHLORIDE CHANNEL; CLNS1A PROTEIN, RAT; ION CHANNEL;

ANIMAL CELL; ARTICLE; ARTIFICIAL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL VOLUME; CONTROLLED STUDY; IMMUNOFLUORESCENCE MICROSCOPY; INSECT; ION CONDUCTANCE; LIGHT SCATTERING; LIPID BILAYER; NONHUMAN; PROTEIN PHOSPHORYLATION; ANIMAL; ARMYWORM; CELL LINE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHEMISTRY; DOG; GENETICS; IN VITRO STUDY; METABOLISM; PHOSPHORYLATION; RAT; SITE DIRECTED MUTAGENESIS;

ANIMALS; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHLORIDE CHANNELS; DOGS; ION CHANNELS; LIPID BILAYERS; LIPOSOMES; MEMBRANE POTENTIALS; MEMBRANES, ARTIFICIAL; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; RATS; RECOMBINANT PROTEINS; SPODOPTERA;

EID: 0032217047     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.112.6.727     Document Type: Article

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