Colorectal cancer vaccines: Antiidiotypic antibody, recombinant protein, and viral vector

Annals of the New York Academy of Sciences

Volumn 910, Issue , 2000, Pages 237-253

  Basak, S ^a   Eck, S ^b   Gutzmer, R ^b   Smith, A J ^b   Birebent, B ^a   Purev, E ^a   Staib, L ^c   Somasundaram, R ^a   Zaloudik, J ^a   Li, W ^a   Jacob, L ^a   Mitchell, E ^d   Speicher, D ^a   Herlyn, D ^a  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF ULM   (Germany)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; CANCER ANTIBODY; CANCER ANTIGEN GA 733; CANCER VACCINE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2; RECOMBINANT PROTEIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; BACULOVIRUS; CANCER IMMUNIZATION; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CANCER; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; HUMAN; MOLECULAR CLONING; MOUSE; NONHUMAN; VACCINATION; VACCINIA VIRUS;

ADENOVIRIDAE; ANIMALIA; MURINAE; UNIDENTIFIED BACULOVIRUS; VACCINIA; VACCINIA VIRUS;

EID: 0033930532     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06712.x     Document Type: Conference Paper

References (50)

1. 1. HAMBY, C.V., S.K. LIAO, T. KANAMURU & S. FERRONE. 1987. Immunogenicity of human melanoma-associated antigens defined by murine monoclonal antibodies in allogeneic and xenogeneic hosts. Cancer Res. 47: 5284-5289.
2. 2. HERLYN, D. & H. KOPROWSKI. 1988. Anti-idiotypic antibodies in cancer therapy. In Biological Applications of Anti-idiotypes, Vol. II. C.A. Bona, Ed.: 123-134. CRC Press. Boca Raton, FL.
3. 3. OLD, L.J. & Y.-T. CHEN. 1998. New paths in human cancer serology. J. Exp. Med. 187: 1163-1167.
4. 4. ROSENBERG, S.A. 1996. The immunotherapy of solid cancers based on cloning the genes encoding tumor-rejection antigens. Annu. Rev. Med. 47: 481-491.
5. 5. LINDAUER, M., T. STANISLAWSKI, A. HÄUSSLER, E. ANTUNES, A. CELLARY, C. HUBER & M. THEOBALD. 1998. The molecular basis of cancer immunotherapy by cytotoxic T lymphocytes. J. Mol. Med. 76: 32-47.
6. 6. JONES, V.E. & M.S. MITCHELL. 1996. Therapeutic vaccines for melanoma: progress and problems. Trends Biotechnol. 14: 349-355.
7. 7. MORTON, D.L., E.C. HOLMES & F R. EILBER. 1982. Adjuvant immunotherapy of malignant melanoma: results of a randomized trial in patients with lymph node metastases. In Immunotherapy of Human Cancer. W.D. Terry & S.A. Rosenberg, Eds.: 245-249. Elsevier North Holland. New York.
8. 8. HERLYN, M. & H. KOPROWSKI. 1988. Melanoma antigens: immunological and biological characterization and clinical significance. Annu. Rev. Immunol. 6: 283-308.
9. 9. HERLYN, M., A. MENRAD & H. KOPROWSKI. 1990. Structure, function, and clinical significance of human tumor antigens. J. Natl. Cancer Inst. 82: 1883-1889.
10. 10. HERLYN, D., J. POWE, A.H. ROSS, M. HERLYN & H. KOPROWSKI. 1985. Inhibition of human tumor growth by IgG2A monoclonal antibodies correlates with antibody density on tumor cells. J. Immunol. 134: 1300-1304.
11. 11. RIETHMULLER, G., E. HOLZ, G. SCHLIMOK, R. RAAB, K. HOFFKEN, P. GRUBER, I. FUNKE, H. PICHLMAIER, H. HIRCHE, P. BUGGISCH, J. WITTE & R. PICHLMAYR. 1998. Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial. J. Clin. Oncol. 16: 1788-1794.
12. 12. HERLYN, M., Z. STEPLEWSKI, D. HERLYN & H. KOPROWSKI. 1979. Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc. Natl. Acad. Sci. USA 76: 1438-1442.
13. 13. HERLYN, D., M. HERLYN, A.H. ROSS, C. ERNST, B. ATKINSON & H. KOPROWSKI. 1984. Efficient selection of human tumor growth-inhibiting monoclonal antibodies. J. Immunol. Methods 73: 157-167.
14. 14. ROSS, A.H., D. HERLYN, D. ILIOPOULOS & H. KOPROWSKI. 1986. Isolation and characterization of a carcinoma-associated antigen. Biochem. Biophys. Res. Commun. 135: 297-303.
15. 15. MACH, J.P., J.F. CHATAL, J.D. LUMBROSO, F. BUCHEGGER, M. FORNI, J. RITSCHARD, C. BERCHE, J.Y. DOUILLARD, S. CARREL, M. HERLYN, Z. STEPLEWSKI & H. KOPROWSKI. 1983. Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma. Cancer Res. 43: 5593-5600.
16. 16. SEARS, H.F., D. HERLYN, M. HERLYN, P.J. GROTZINGER, Z. STEPLEWSKI, W. GERHARD & H. KOPROWSKI. 1981. Ex vivo perfusion of a tumor-containing colon with monoclonal antibody. J. Surg. Res. 31: 145-150.
17. 17. SEARS, H.F., D. HERLYN, M. HERLYN, Z. STEPLEWSKI, P. GROTZINGER & H. KOPROWSKI. 1982. Ex vivo perfusion of human colon with monoclonal anti-colorectal cancer antibodies. Cancer 49: 1231-1235.
18. 18. POWE, J., D. HERLYN, A. ALAVI, D. MUNZ, Z. STEPLEWSKI & H. KOPROWSKI. 1985. Radioimmunodetection of human tumor xenografts by monoclonal antibodies correlates with antibody density and affinity. In Immunoscintigraphy. K. Button & L. Donato, Eds.: 135-152. Gordon and Breach Science. New York.
19. 19. ROSS, A.H., D. HERLYN, Z. STEPLEWSKI & H. KOPROWSKI. 1989. Monoclonal antibodies as applied to tumor-associated antigens. The CO17-1A antigen. In Human Immunogenetics. Basic Principles and Clinical Relevance. S.D. Litwin, Ed.: 107-122. Marcel Dekker. New York.
20. 20. RIETHMÜLLER, G., E. SCHNEIDER-GÄDICKE, G. SCHLIMOK, W. SCHMIEGEL, R. RAAB, K. HOFEKEN, R. GRUBER, H. PICHLMAIER, H. HIRCHE, R. PICHLMAYR, P. BUGGISCH, J. WITTE & THE GERMAN CANCER AID 17-1A STUDY GROUP. 1994. Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. Lancet 343: 1177-1183.
21. 21. HERLYN, D., A.H. ROSS & H. KOPROWSKI. 1986. Anti-idiotypic antibodies bear the internal image of a human tumor antigen. Science 232: 100-102.
22. 22. HERLYN, D., A.H. ROSS, D. ILIOPOULOS & H. KOPROWSKI. 1987. Induction of specific immunity to human colon carcinoma by anti-idiotype antibodies to monoclonal antibody CO17-1A. Eur. J. Immunol. 17: 1649-1652.
23. 23. HERLYN, D., D. HARRIS, J. ZALOUDIK, M. SPERLAGH, H. MARUYAMA, L. JACOB, M.P. KIENY, S. SCHECK, R. SOMASUNDARAM, E. HART, H. ERTL & M. MASTRANGELO. 1994. Immunomodulatory activity of monoclonal anti-idiotypic antibody to anticolorectal carcinoma antibody CO17-1A in animals and patients. J. Immunother. 15: 303-311.
24. 24. KOIDO, T., S. SCHECK & D. HERLYN. 1995. Induction of immunity to colon carcinoma antigen CO17-1A by monoclonal anti-idiotype (Ab2): effects of Ab2 fragmentation, carrier and adjuvant. Tumor Targeting 1: 115-124.
25. 25. MARUYAMA, H., A. BENDEN, J. ZALOUDIK, T. KOIDO, W. LI, J.-L. TAUPIN, B. ACRES, R. SOMASUNDARAM, M. PREWETT & D. HERLYN. 1996. Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733. Int. J. Cancer 65: 547-553.
26. 26. HERLYN, D., M. WETTENDORFF, E. SCHMOLL, D. ILIOPOULOS, I. SCHEDEL, U. DREIKHAUSEN, R. RAAB, A.H. ROSS, H. JAKSCHE, M. SCRIBA & H. KOPROWSKI. 1987. Anti-idiotype immunization of cancer patients: modulation of the immune response. Proc. Natl. Acad. Sci. USA 84: 8055-8059.
27. 27. HERLYN, D., A. BENDEN, M. KANE, R. SOMASUNDARAM, J. ZALOUDIK, M. SPERLAGH, G. MARKS, E. HART, C. RALPH, M. WETTENDORFF & M. MASTRANGELO. 1991. Anti-idiotype cancer vaccines: pre-clinical and clinical studies. In Vivo 5: 615-624.
28. 28. SOMASUNDARAM, R., J. ZALOUDIK, L. JACOB, A. BENDEN, M. SPERLAGH, E. HART, G. MARKS, M. KANE, M. MASTRANGELO & D. HERLYN. 1995. Induction of T-and B-cell immunity in colon carcinoma patients by anti-idiotypic antibody. J. Immunol. 155: 3253-3261.
29. 29. LIVINGSTON, P.O., S. ZHANG & K.O. LLOYD. 1997. Carbohydrate vaccines that induce antibodies against cancer. 1. Rationale. Cancer Immunol. Immunother. 45: 1-9.
30. 30. LIVINGSTON, P.O. & G. RAGUPATHI. 1997. Carbohydrate vaccines that induce antibodies against cancer. 2. Previous experience and future plans. Cancer Immunol. Immunother. 45: 10-19.
31. 31. BYSTRYN, J.C., S. JACOBSON, M. HARRIS, D. ROSES, J. SPEYER & M. LEVIN. 1986. Preparation and characterization of a polyvalent human melanoma antigen vaccine. J. Biol. Resp. Mod. 5: 211-224.
32. 32. ZBAR, A.P., N.R. LEMOINE, M. WADHWA, H. THOMAS, D. SNARY & W.A. KMIOT. 1998. Biological therapy: approaches in colorectal cancer. Br. J. Cancer 77: 683-693.
33. 33. ROSENBERG, S.A., Y. ZHAI, J.C. YANG, D.J. SCHWARTZENTRUBER, P. HWU, F.M. MARINCOLA, S.L. TOPALIAN, N.P. RESTIFO, C.A. SEIPP, J.H. EINHORN, B. ROBERTS & D.E. WHITE. 1998. Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens. J. Natl. Cancer Inst. 90: 1894-1900.
34. 34. SZALA, S., M. FROEHLICH, M. SCOLLON, Y. KASAI, Z. STEPLEWSKI, H. KOPROWSKI & A.J. LINNENBACH. 1990. Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2. Proc. Natl. Acad. Sci. USA 87: 3542-3546.
35. 35. STRASSBURG, C.P., Y. KASAI, B.A. SENG, P. MINIOU, J. ZALOUDIK, D. HERLYN, H. KOPROWSKI & A.J. LINNENBACH. 1992. Baculovirus recombinant expressing a secreted form of a trans-membrane carcinoma-associated antigen. Cancer Res. 52: 815-821.
36. 36. LI, W., K. BERENCSI, S. BASAK, R. SOMASUNDARAM, R.P. RICCIARDI, E. GONCZOL, J. ZALOUDIK, A. LINNENBACH, H. MARUYAMA, P. MINIOU & D. HERLYN. 1997. Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by recombinant adenovirus inhibits growth of established CRC cells in mice. J. Immunol. 159: 763-769.
37. 37. BIREBENT, B., L. PUREV, W. LI, N. AKIS, L. STAIB, R. SOMASUNDARAM, C. ANDL, E. MITCHELL, S. NAIR & D. HERLYN. 1999. Anti-idiotype and recombinant antigen (Ag) vaccines. Proc. Am. Assoc. Cancer Res. 40: Abstr. #2242.
38. 38. HAREUVENI, M., C. GAUTIER, M.P. KIENY, D. WRESCHNER, P. CHAMBON & R. LATHE. 1990. Vaccination against tumor cells expressing breast cancer epithelial tumor antigen. Proc. Natl. Acad. Sci. USA 87: 9498-9502.
39. 39. MARSHALL, G.S., R.P. RICCIARDI, R. RANDO, R. GE, J. PUCH, S.A. PLOTKIN & E. GONCZOL. 1990. An adenovirus recombinant that expresses the human cytomegalovirus major envelope glycoprotein and induces neutralizing antibodies. J. Infect. Dis. 162: 1177-1181.
40. 40. SMITH, J.G., S.E. RAPER, E. WHEELDON, D. HACKNEY, K. JUDY, J.M. WILSON & S.L. ECK. 1997. Intracranial administration of adenovirus expressing HSVTK in combination with ganciclovir produces a self-limited, dose-dependent inflammatory response. Hum. Gene Ther. 8: 943-954.
41. 41. BASAK, S.K., D.W. SPEICHER, S. ECK, W. WUNNER, G. MAUL, M. SIMMONS & D. HERLYN. 1998. Colorectal carcinoma growth and invasion inhibition by CO17-1A/ GA733 antigen and its murine homologue. J. Natl. Cancer Inst. 90: 691-697.
42. 42. ZALOUDIK, J., S. BASAK, E. MILLER, M. NESBIT, D. SPEICHER, W. WUNNER, C. ERNSTGROTKOWSKI, R. KENNEDY, P.L. BERGSAGEL, T. KOIDO & D. HERLYN. 1997. Expression of an antigen homologous to the human gastrointestinal carcinoma-associated antigen GA733 in normal tissues of experimental animals. Br. J. Cancer 76: 909-916.
43. 43. HERLYN, D., S. BASAK, W. LI, R. SOMASUNDARAM, B. BIREBENT, P. ENKHTSETSEG & S. ECK. 1999. Recombinant colorectal cancer (CRC) antigen vaccines. J. Hum. Virol. 2: 203.
44. 44. LOIBNER, H., R. PLOT, A. ROT, G. WERNER, M. WRANN, H. SAMONIGG, M. SCHMID, H. STOGER, M. TRUSCHNIG, D. HERLYN & H. KOPROWSKI. 1990. Immunoreactivity of patient with colorectal cancer metastasis after immunization with anti-idiotypes. Lancet 335: 171.
45. 45. SAMONIGG, H., M. WILDERS-TRUSCHNIG, H. LOIBNER, R. PLOT, A. ROT, I. KUSS, G. WERNER, H. STOGER, M. WRANN, D. HERLYN & H. KOPROWSKI. 1992. Immune response to tumor antigens in a patient with colorectal cancer after immunization with anti-idiotype antibody. Clin. Immunol. Immunopathol. 65: 271-277.
46. 46. HIRSHAUT, Y. & F. SLOVIN. 1985. Harnessing T-lymphocytes for human cancer immunotherapy. Cancer 56: 1366-1373.
47. 47. SAEKI, Y., J.J. CHEN, L.F. SHI & H. KOHLER. 1989. Idiotypic intramolecular idiotypic antibody with the help of Fc-specific T helper clones. J. Immunol. 142: 2629-2634.
48. 48. GÖTTLINGER, H.G., I. FUNKE, J.P. JOHNSON, J.M. GOKEI. & G. RIETHMULLER. 1986. The epithelial cell surface antigen 17-1A, a target for antibody-mediated tumor therapy: its biochemical nature, tissue distribution and recognition by different monoclonal antibodies. Int. J. Cancer 38: 47-53.
49. 49. DURRANT, L.G., D.J. BUKLEY, I. SPENDLOVE & R.A. ROBINS. 1997. Low doses of 105ad7 cancer vaccine preferentialy stimulate anti-tumor t-cell immunity. Hybridoma 16: 23-26.
50. 50. FOON, K.A., W.J. JOHN, M. CHJAKRABORTY, A. SHERRATT, J. GARRISON, M. FLETT & M. BHATTACHARYA-CHATTERJEE. 1997. Clinical and immune responses in advanced colorectal cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen. Clin. Cancer Res. 3: 1267-1276.